Search Results - "MIZISIN, Andrew P"

Homeostatic regulation of the endoneurial microenvironment during development, aging and in response to trauma, disease and toxic insult by Mizisin, Andrew P., Weerasuriya, Ananda

“…The endoneurial microenvironment, delimited by the endothelium of endoneurial vessels and a multi-layered ensheathing perineurium, is a specialized milieu…”
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The blood-nerve barrier: structure and functional significance by Weerasuriya, Ananda, Mizisin, Andrew P

“…The blood-nerve barrier (BNB) defines the physiological space within which the axons, Schwann cells, and other associated cells of a peripheral nerve function…”
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The MMP-9/TIMP-1 axis controls the status of differentiation and function of myelin-forming Schwann cells in nerve regeneration by Kim, Youngsoon, Remacle, Albert G, Chernov, Andrei V, Liu, Huaqing, Shubayev, Igor, Lai, Calvin, Dolkas, Jennifer, Shiryaev, Sergey A, Golubkov, Vladislav S, Mizisin, Andrew P, Strongin, Alex Y, Shubayev, Veronica I

“…Myelinating Schwann cells (mSCs) form myelin in the peripheral nervous system. Because of the works by us and others, matrix metalloproteinase-9 (MMP-9) has…”
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Nesprin 1 is critical for nuclear positioning and anchorage by Zhang, Jianlin, Felder, Amanda, Liu, Yujie, Guo, Ling T., Lange, Stephan, Dalton, Nancy D., Gu, Yusu, Peterson, Kirk L., Mizisin, Andrew P., Shelton, G. Diane, Lieber, Richard L., Chen, Ju

“…Nesprin 1 is an outer nuclear membrane protein that is thought to link the nucleus to the actin cytoskeleton. Recent data suggest that mutations in Nesprin 1…”
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Hypertension-induced peripheral neuropathy and the combined effects of hypertension and diabetes on nerve structure and function in rats by Gregory, Joshua A., Jolivalt, Corinne G., Goor, Jared, Mizisin, Andrew P., Calcutt, Nigel A.

“…Diabetic neuropathy includes damage to neurons, Schwann cells and blood vessels. Rodent models of diabetes do not adequately replicate all pathological…”
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MTM1 mutation associated with X-linked myotubular myopathy in Labrador Retrievers by Beggs, Alan H., Böhm, Johann, Snead, Elizabeth, Kozlowski, Marek, Maurer, Marie, Minor, Katie, Childers, Martin K., Taylor, Susan M., Hitte, Christophe, Mickelson, James R., Guo, Ling T., Mizisin, Andrew P., Buj-Bello, Anna, Tiret, Laurent, Laporte, Jocelyn, Shelton, G. Diane, Kunkel, Louis M.

“…Mutations in the MTM1 gene encoding myotubularin cause X-linked myotubular myopathy (XLMTM), a well-defined subtype of human centronuclear myopathy. Seven male…”
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Electrodiagnostic Testing and Histopathologic Changes Confirm Peripheral Nervous System Myelin Abnormalities in the Feline Model of Niemann-Pick Disease Type C by Bagel, Jessica H, Sikora, Tracey U, Prociuk, Maria, Pesayco, Jill P, Mizisin, Andrew P, Shelton, G Diane, Vite, Charles H

“…ABSTRACTNiemann-Pick disease type C (NPC disease) is an incurable, neurodegenerative, autosomal recessive disease caused by mutations in either the NPC1 or the…”
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Epidermal nerve fiber quantification in the assessment of diabetic neuropathy by Beiswenger, Kristina K., Calcutt, Nigel A., Mizisin, Andrew P.

“…Assessment of cutaneous innervation in skin biopsies is emerging as a valuable means of both diagnosing and staging diabetic neuropathy. Immunolabeling, using…”
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Secretion of amyloidogenic gelsolin progressively compromises protein homeostasis leading to the intracellular aggregation of proteins by Page, Lesley J, Suk, Ji Young, Bazhenova, Lyudmila, Fleming, Sheila M, Wood, Malcolm, Jiang, Yun, Guo, Ling T, Mizisin, Andrew P, Kisilevsky, Robert, Shelton, G. Diane, Balch, William E, Kelly, Jeffery W

“…Familial amyloidosis of Finnish type (FAF) is a systemic amyloid disease associated with the deposition of proteolytic fragments of mutant (D187N/Y) plasma…”
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Mechanisms of diabetic neuropathy: Schwann cells by Mizisin, Andrew P

“…As ensheathing and secretory cells, Schwann cells are a ubiquitous and vital component of the endoneurial microenvironment of peripheral nerves. The…”
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Ciliary Neurotrophic Factor Improves Nerve Conduction and Ameliorates Regeneration Deficits in Diabetic Rats by MIZISIN, Andrew P, VU, Yvonne, SHUFF, Michelle, CALCUTT, Nigel A

“…Ciliary Neurotrophic Factor Improves Nerve Conduction and Ameliorates Regeneration Deficits in Diabetic Rats Andrew P. Mizisin , Yvonne Vu , Michelle Shuff and…”
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Impaired Prosaposin Secretion During Nerve Regeneration in Diabetic Rats and Protection of Nerve Regeneration by a Prosaposin-Derived Peptide by Jolivalt, Corinne G, Vu, Yvonne, Mizisin, Leah M, Mizisin, Andrew P, Calcutt, Nigel A

“…Prosaposin is both a precursor of sphingolipid activator proteins and a secreted neurotrophic and myelinotrophic factor. Because peripheral nerve regeneration…”
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Novel sites of aldose reductase immunolocalization in normal and streptozotocin-diabetic rats by Jiang, Yun, Calcutt, Nigel A., Rames, Khara M., Mizisin, Andrew P.

“…Glucose metabolism by aldose reductase (AR) is implicated in the pathogenesis of many diabetic complications, including neuropathy. We have re‐evaluated the…”
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Neurotrophin-3 Prevents the Proximal Accumulation of Neurofilament Proteins in Sensory Neurons of Streptozocin-Induced Diabetic Rats by SAYERS, Nicola M, BESWICK, Lisa J, MIDDLEMAS, Alicia, CALCUTT, Nigel A, MIZISIN, Andrew P, TOMLINSON, David R, FERNYHOUGH, Paul

“…Neurotrophin-3 Prevents the Proximal Accumulation of Neurofilament Proteins in Sensory Neurons of Streptozocin-Induced Diabetic Rats Nicola M. Sayers 1 , Lisa…”
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The ER-bound RING finger protein 5 (RNF5/RMA1) causes degenerative myopathy in transgenic mice and is deregulated in inclusion body myositis by Delaunay, Agnès, Bromberg, Kenneth D, Hayashi, Yukiko, Mirabella, Massimiliano, Burch, Denise, Kirkwood, Brian, Serra, Carlo, Malicdan, May C, Mizisin, Andrew P, Morosetti, Roberta, Broccolini, Aldobrando, Guo, Ling T, Jones, Stephen N, Lira, Sergio A, Puri, Pier Lorenzo, Shelton, G Diane, Ronai, Ze'ev

“…Growing evidence supports the importance of ubiquitin ligases in the pathogenesis of muscular disorders, although underlying mechanisms remain largely elusive…”
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Dissociation of thermal hypoalgesia and epidermal denervation in streptozotocin-diabetic mice by Beiswenger, Kristina K., Calcutt, Nigel A., Mizisin, Andrew P.

“…The quantification of epidermal innervation, which consists primarily of heat-sensitive C-fibers, is emerging as a tool for diagnosing and staging diabetic…”
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Repeated monitoring of corneal nerves by confocal microscopy as an index of peripheral neuropathy in type-1 diabetic rodents and the effects of topical insulin by Chen, Debbie K., Frizzi, Katie E., Guernsey, Lucie S., Ladt, Kelsey, Mizisin, Andrew P., Calcutt, Nigel A.

“…We developed a reliable imaging and quantitative analysis method for in vivo corneal confocal microscopy (CCM) in rodents and used it to determine whether…”
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Reactive, degenerative, and proliferative Schwann cell responses in experimental galactose and human diabetic neuropathy by KALICHMAN, M. W, POWELL, H. C, MIZISIN, A. P

“…Despite early descriptions of hypertrophic Schwann cells and onion-bulb formation in patients with diabetic neuropathy, clinical and experimental studies have…”
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Degenerative myelopathy associated with a missense mutation in the superoxide dismutase 1 ( SOD1 ) gene progresses to peripheral neuropathy in Pembroke Welsh Corgis and Boxers by Shelton, G. Diane, Johnson, Gayle C, O'Brien, Dennis P, Katz, Martin L, Pesayco, Jill P, Chang, Brian J, Mizisin, Andrew P, Coates, Joan R

“…Abstract Canine degenerative myelopathy (DM) is an adult-onset, fatal neurodegenerative disease with many similarities to an upper-motor-neuron-onset form of…”
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Reduced heat sensitivity and epidermal nerve fiber immunostaining following single applications of a high-concentration capsaicin patch by Malmberg, Annika B., Mizisin, Andrew P., Calcutt, Nigel A., von Stein, Thorsten, Robbins, Wendye R., Bley, Keith R.

“…Capsaicin-containing plant extracts have been used as topical treatments for a variety of pain syndromes for many centuries. Current products containing…”
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