Search Results - "MIYOSHI, EIJI"

High Dye-Loaded and Thin-Shell Fluorescent Polymeric Nanoparticles for Enhanced FRET Imaging of Protein-Specific Sialylation on the Cell Surface by Zhao, Tingbi, Masuda, Tsukuru, Miyoshi, Eiji, Takai, Madoka

“…Nanoparticle-based probes have great potential for imaging specific biomolecules in signal distinguishing and amplification via Förster resonance energy…”
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Functional roles of N‐glycans in cell signaling and cell adhesion in cancer by Zhao, Yan‐Yang, Takahashi, Motoko, Gu, Jian‐Guo, Miyoshi, Eiji, Matsumoto, Akio, Kitazume, Shinobu, Taniguchi, Naoyuki

“…Glycosylation is one of the most common post‐translational modification reactions and nearly half of all known proteins in eukaryotes are glycosylated. In…”
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Application of glycoscience to the early detection of pancreatic cancer by Miyoshi, Eiji, Kamada, Yoshihiro

“…The prognosis of pancreatic cancer is extremely poor compared to other cancers. One of the reasons for this is the difficulty of early diagnosis. Surveillance…”
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Functional glycomics: Application to medical science and hepatology by Miyoshi, Eiji, Kamada, Yoshihiro, Suzuki, Tadashi

“…Glycomics refers to the comprehensive analysis of glycans. Recent progress in glycotechnology enables the determination of a variety of biological functions of…”
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Sweet modification and regulation of death receptor signalling pathway by Moriwaki, Kenta, Chan, Francis K M, Miyoshi, Eiji

“…Abstract Death receptors, members of the tumour necrosis factor receptor (TNFR) superfamily, are characterized by the presence of a death domain in the…”
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Simultaneous analysis of serum α2,3-linked sialylation and core-type fucosylation of prostate-specific antigen for the detection of high-grade prostate cancer by Hatano, Koji, Yoneyama, Tohru, Hatakeyama, Shingo, Tomiyama, Eisuke, Tsuchiya, Mutsumi, Nishimoto, Mitsuhisa, Yoshimura, Kazuhiro, Miyoshi, Eiji, Uemura, Hirotsugu, Ohyama, Chikara, Nonomura, Norio, Fujita, Kazutoshi

“…Background Altered prostate-specific antigen (PSA) glycosylation patterns can be useful biomarkers in detecting high-grade prostate cancer (HGPC). The…”
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Establishment of a novel 70K Mac-2 binding protein antibody through screening of fucosylation-related antibodies by Masuda, Mika, Asuka, Tatsuya, Terao, Naoko, Nishino, Shinsuke, Ikeda, Shun, Takamatsu, Shinji, Kondo, Jumpei, Miyoshi, Eiji

“…Mac-2 binding protein (Mac-2bp) is a serum glycoprotein that contains seven N-glycans, and Mac-2bp serum levels are increased in patients with several types of…”
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Possible involvement of Enterococcus infection in the pathogenesis of chronic pancreatitis and cancer by Maekawa, Tomohiro, Fukaya, Risako, Takamatsu, Shinji, Itoyama, Saki, Fukuoka, Tomoya, Yamada, Makoto, Hata, Tomoki, Nagaoka, Satoshi, Kawamoto, Koichi, Eguchi, Hidetoshi, Murata, Kohei, Kumada, Takashi, Ito, Toshifumi, Tanemura, Masahiro, Fujimoto, Kahoko, Tomita, Yasuhiko, Tobe, Toru, Kamada, Yoshihiro, Miyoshi, Eiji

“…(Aim) Bacterial infection underlies the pathogenesis of many human diseases, including acute and chronic inflammation. Here, we investigated a possible role…”
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Biological Function of Fucosylation in Cancer Biology by Miyoshi, Eiji, Moriwaki, Kenta, Nakagawa, Tsutomu

“…Fucosylation is one of the most common modifications involving oligosaccharides on glycoproteins or glycolipids. Fucosylation comprises the attachment of a…”
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Serum core‐type fucosylated prostate‐specific antigen index for the detection of high‐risk prostate cancer by Fujita, Kazutoshi, Hatano, Koji, Tomiyama, Eisuke, Hayashi, Yujiro, Matsushita, Makoto, Tsuchiya, Mutsumi, Yoshikawa, Tomoyasu, Date, Mutsuhiro, Miyoshi, Eiji, Nonomura, Norio

“…It is known that core‐type fucosylation is higher in prostate cancer cells than in other cancer cell types and is associated with high‐risk prostate cancer…”
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The Rab11-binding protein RELCH/KIAA1468 controls intracellular cholesterol distribution by Sobajima, Tomoaki, Yoshimura, Shin-Ichiro, Maeda, Tomomi, Miyata, Haruhiko, Miyoshi, Eiji, Harada, Akihiro

“…Cholesterol, which is endocytosed to the late endosome (LE)/lysosome, is delivered to other organelles through vesicular and nonvesicular transport mechanisms…”
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Branched-chain amino acids protect the liver from cirrhotic injury via suppression of activation of lipopolysaccharide-binding protein, toll-like receptor 4, and signal transducer and activator of transcription 3, as well as Enterococcus faecalis translocation by Eguchi, Akiko, Iwasa, Motoh, Tamai, Yasuyuki, Tempaku, Mina, Takamatsu, Shinji, Miyoshi, Eiji, Hasegawa, Hiroshi, Kobayashi, Yoshinao, Takei, Yoshiyuki

“…Branched-chain amino acids (BCAAs) are used as nutritional support and for improving prognosis in liver cirrhosis. Here we investigate the molecular mechanisms…”
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Fucosylation in Urological Cancers by Fujita, Kazutoshi, Hatano, Koji, Hashimoto, Mamoru, Tomiyama, Eisuke, Miyoshi, Eiji, Nonomura, Norio, Uemura, Hirotsugu

“…Fucosylation is an oligosaccharide modification that plays an important role in immune response and malignancy, and specific fucosyltransferases (FUTs)…”
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Metabolic clogging of mannose triggers dNTP loss and genomic instability in human cancer cells by Harada, Yoichiro, Mizote, Yu, Suzuki, Takehiro, Hirayama, Akiyoshi, Ikeda, Satsuki, Nishida, Mikako, Hiratsuka, Toru, Ueda, Ayaka, Imagawa, Yusuke, Maeda, Kento, Ohkawa, Yuki, Murai, Junko, Freeze, Hudson H, Miyoshi, Eiji, Higashiyama, Shigeki, Udono, Heiichiro, Dohmae, Naoshi, Tahara, Hideaki, Taniguchi, Naoyuki

“…Mannose has anticancer activity that inhibits cell proliferation and enhances the efficacy of chemotherapy. How mannose exerts its anticancer activity,…”
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Impact of fatty pancreas and lifestyle on the development of subclinical chronic pancreatitis in healthy people undergoing a medical checkup by Fujii, Makoto, Ohno, Yuko, Yamada, Makoto, Kamada, Yoshihiro, Miyoshi, Eiji

“…Although fat accumulation in human organs is associated with a variety of diseases, there is little evidence about the effect of a fatty pancreas on the…”
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Development of new colloid osmotic pressure measurement method using ultrafiltration membrane during cardiopulmonary bypass by Matsumoto, Takeshi, Yoshida, Kiyoshi, Shinohara, Tomotaka, Miyoshi, Eiji, Ueno, Takayoshi

“…Clinical practice of measuring colloid osmotic pressure (COP) was abandoned after correcting hypoosmolarity did not improve overall patient outcomes. However,…”
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Diagnostic accuracy of enhanced liver fibrosis test for nonalcoholic steatohepatitis‐related fibrosis: Multicenter study by Seko, Yuya, Takahashi, Hirokazu, Toyoda, Hidenori, Hayashi, Hideki, Yamaguchi, Kanji, Iwaki, Michihiro, Yoneda, Masato, Arai, Taeang, Shima, Toshihide, Fujii, Hideki, Morishita, Asahiro, Kawata, Kazuhito, Tomita, Kengo, Kawanaka, Miwa, Yoshida, Yuichi, Ikegami, Tadashi, Notsumata, Kazuo, Oeda, Satoshi, Kamada, Yoshihiro, Sumida, Yoshio, Fukushima, Hideaki, Miyoshi, Eiji, Aishima, Shinichi, Okanoue, Takeshi, Nakajima, Atsushi, Itoh, Yoshito

“…Aim The enhanced liver fibrosis (ELF) test is a noninvasive method for diagnosing hepatic fibrosis in patients with nonalcoholic fatty liver disease (NAFLD)…”
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Core Fucosylation Is Required for the Secretion of and the Enzymatic Activity of SOD3 in Nonsmall-Cell Lung Cancer Cells by Ohkawa, Yuki, Kitano, Masato, Maeda, Kento, Nakano, Miyako, Kanto, Noriko, Kizuka, Yasuhiko, Seike, Masahiro, Azuma, Arata, Yamaguchi, Yoshiki, Ookawara, Tomomi, Miyoshi, Eiji, Taniguchi, Naoyuki

“…The anticancer function of superoxide dismutases (SODs) is still controversial. SOD3 is an extracellular superoxide dismutase and contains a single -glycan…”
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Fucosylation and gastrointestinal cancer by Moriwaki, Kenta, Miyoshi, Eiji

“…Fucose (6-deoxy-L-galactose) is a monosaccharide that is found on glycoproteins and glycolipids in verteb rates, invertebrates, plants, and bacteria…”
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The scaffold-dependent function of RIPK1 in dendritic cells promotes injury-induced colitis by Moriwaki, Kenta, Park, Christa, Koyama, Kazuha, Balaji, Sakthi, Kita, Kohei, Yagi, Ryoko, Komazawa-Sakon, Sachiko, Semba, Manami, Asuka, Tatsuya, Nakano, Hiroyasu, Kamada, Yoshihiro, Miyoshi, Eiji, Chan, Francis K. M.

“…Receptor interacting protein kinase 1 (RIPK1) is a cytosolic multidomain protein that controls cell life and death. While RIPK1 promotes cell death through its…”
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