Search Results - "MIYAZATO, Paola"

Identification and characterization of a novel enhancer in the HTLV-1 proviral genome by Matsuo, Misaki, Ueno, Takaharu, Monde, Kazuaki, Sugata, Kenji, Tan, Benjy Jek Yang, Rahman, Akhinur, Miyazato, Paola, Uchiyama, Kyosuke, Islam, Saiful, Katsuya, Hiroo, Nakajima, Shinsuke, Tokunaga, Masahito, Nosaka, Kisato, Hata, Hiroyuki, Utsunomiya, Atae, Fujisawa, Jun-ichi, Satou, Yorifumi

“…Human T-cell leukemia virus type 1 (HTLV-1) is a retrovirus that causes adult T-cell leukemia/lymphoma (ATL), a cancer of infected CD4 + T-cells. There is both…”
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1mΨ influences the performance of various positive-stranded RNA virus-based replicons by Miyazato, Paola, Noguchi, Takafumi, Ogawa, Fumiyo, Sugimoto, Takeshi, Fauzyah, Yuzy, Sasaki, Ryo, Ebina, Hirotaka

“…Self-amplifying RNAs (saRNAs) are versatile vaccine platforms that take advantage of a viral RNA-dependent RNA polymerase (RdRp) to amplify the messenger RNA…”
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The retrovirus HTLV-1 inserts an ectopic CTCF-binding site into the human genome by Satou, Yorifumi, Miyazato, Paola, Ishihara, Ko, Yaguchi, Hiroko, Melamed, Anat, Miura, Michi, Fukuda, Asami, Nosaka, Kisato, Watanabe, Takehisa, Rowan, Aileen G., Nakao, Mitsuyoshi, Bangham, Charles R. M.

“…Human T-lymphotropic virus type 1 (HTLV-1) is a retrovirus that causes malignant and inflammatory diseases in ∼10% of infected people. A typical host has…”
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Safety and immunogenicity of parvovirus B19 virus-like particle vaccine lacking phospholipase A2 activity by Suzuki, Hidehiko, Noguchi, Takafumi, Matsugu, Noriko, Suzuki, Akio, Kimura, Sakika, Onishi, Misa, Kosaka, Mitsuyo, Miyazato, Paola, Morita, Eiji, Ebina, Hirotaka

“…•⊿PLA2 B19 VLPs-immunization did not cause inflammation in mice.•B19 PLA2 domain does not constitute an important human CD4+ T cell epitope.•⊿PLA2 B19 VLPs…”
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Fusion of parvovirus B19 receptor-binding domain and pneumococcal surface protein A induces protective immunity against parvovirus B19 and Streptococcus pneumoniae by Suzuki, Hidehiko, Noguchi, Takafumi, Ogawa, Keiji, Miyazato, Paola, Hatakeyama, Yu, Morita, Eiji, Ebina, Hirotaka

“…•B19 RBD alone could not induce neutralizing antibodies due to poor T cell-activation.•RBD-PspA enhanced immunogenicity of RBD, generating parvovirus…”
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HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo by Satou, Yorifumi, Yasunaga, Jun-Ichirou, Zhao, Tiejun, Yoshida, Mika, Miyazato, Paola, Takai, Ken, Shimizu, Kei, Ohshima, Koichi, Green, Patrick L, Ohkura, Naganari, Yamaguchi, Tomoyuki, Ono, Masahiro, Sakaguchi, Shimon, Matsuoka, Masao

“…Human T-cell leukemia virus type 1 (HTLV-1) is the causal agent of a neoplastic disease of CD4+ T cells, adult T-cell leukemia (ATL), and inflammatory diseases…”
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HIV-1 DNA-capture-seq is a useful tool for the comprehensive characterization of HIV-1 provirus by Iwase, Saori C., Miyazato, Paola, Katsuya, Hiroo, Islam, Saiful, Yang, Benjy Tan Jek, Ito, Jumpei, Matsuo, Misaki, Takeuchi, Hiroaki, Ishida, Takaomi, Matsuda, Kouki, Maeda, Kenji, Satou, Yorifumi

“…Regardless of recent advances in the development of anti-retroviral drugs, it is still extremely difficult to eradicate HIV-1 from infected individuals. The…”
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HTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors by Kinosada, Haruka, Yasunaga, Jun-Ichirou, Shimura, Kazuya, Miyazato, Paola, Onishi, Chiho, Iyoda, Tomonori, Inaba, Kayo, Matsuoka, Masao

“…Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia-lymphoma (ATL) and inflammatory diseases. To enhance cell-to-cell transmission of…”
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The Nature of the HTLV-1 Provirus in Naturally Infected Individuals Analyzed by the Viral DNA-Capture-Seq Approach by Katsuya, Hiroo, Islam, Saiful, Tan, Benjy Jek Yang, Ito, Jumpei, Miyazato, Paola, Matsuo, Misaki, Inada, Yuki, Iwase, Saori C., Uchiyama, Yoshikazu, Hata, Hiroyuki, Sato, Tomoo, Yagishita, Naoko, Araya, Natsumi, Ueno, Takaharu, Nosaka, Kisato, Tokunaga, Masahito, Yamagishi, Makoto, Watanabe, Toshiki, Uchimaru, Kaoru, Fujisawa, Jun-ichi, Utsunomiya, Atae, Yamano, Yoshihisa, Satou, Yorifumi

“…The retrovirus human T-cell leukemia virus type 1 (HTLV-1) integrates into the host DNA, achieves persistent infection, and induces human diseases. Here, we…”
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HTLV-1 bZIP factor induces inflammation through labile Foxp3 expression by Yamamoto-Taguchi, Nanae, Satou, Yorifumi, Miyazato, Paola, Ohshima, Koichi, Nakagawa, Masanori, Katagiri, Koko, Kinashi, Tatsuo, Matsuoka, Masao

“…Human T-cell leukemia virus type 1 (HTLV-1) causes both a neoplastic disease and inflammatory diseases, including HTLV-1-associated myelopathy/tropical spastic…”
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HTLV-1 contains a high CG dinucleotide content and is susceptible to the host antiviral protein ZAP by Miyazato, Paola, Matsuo, Misaki, Tan, Benjy J Y, Tokunaga, Michiyo, Katsuya, Hiroo, Islam, Saiful, Ito, Jumpei, Murakawa, Yasuhiro, Satou, Yorifumi

“…Human T cell leukaemia virus type 1 (HTLV-1) is a retrovirus associated with human diseases such as adult T-cell leukaemia/lymphoma and HTLV-1 associated…”
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Protocol to isolate temperature-sensitive SARS-CoV-2 mutants and identify associated mutations by Okamura, Shinya, Yoshida, Akiho, Miyazato, Paola, Matsumoto, Mai, Ebina, Hirotaka

“…An inability to proliferate at high temperatures typically gives viruses an attenuated phenotype. Here, we present a protocol to obtain and isolate…”
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Human T-cell leukemia virus type 1 and Foxp3 expression: viral strategy in vivo by Miyazato, Paola, Matsuoka, Masao

“…Human T-cell leukemia virus type 1 (HTLV-1) is the causal agent of adult T-cell leukemia (ATL) and inflammatory diseases, including HTLV-1-associated…”
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Transcriptional and Epigenetic Regulatory Mechanisms Affecting HTLV-1 Provirus by Miyazato, Paola, Matsuo, Misaki, Katsuya, Hiroo, Satou, Yorifumi

“…Human T-cell leukemia virus type 1 (HTLV-1) is a retrovirus associated with human diseases, such as adult T-cell leukemia (ATL) and HTLV-1-associated…”
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Clonality of HIV-1– and HTLV-1–Infected Cells in Naturally Coinfected Individuals by Katsuya, Hiroo, Cook, Lucy B M, Rowan, Aileen G, Melamed, Anat, Turpin, Jocelyn, Ito, Jumpei, Islam, Saiful, Miyazato, Paola, Jek Yang Tan, Benjy, Matsuo, Misaki, Miyakawa, Toshikazu, Nakata, Hirotomo, Matsushita, Shuzo, Taylor, Graham P, Bangham, Charles R M, Kimura, Shinya, Satou, Yorifumi

“…Abstract Background Coinfection with human immunodeficiency virus type 1 (HIV-1) and human T-cell leukemia virus type 1 (HTLV-1) diminishes the value of the…”
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Impact of HIV-1 infection pathways on susceptibility to antiviral drugs and on virus spread by Shimura, Kazuya, Miyazato, Paola, Oishi, Shinya, Fujii, Nobutaka, Matsuoka, Masao

“…Abstract The infection routes of HIV-1 can affect several viral properties, including dissemination, pathogenesis, and immune evasion. In this study, we…”
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IL-2/IL-2 Receptor Pathway Plays a Crucial Role in the Growth and Malignant Transformation of HTLV-1-Infected T Cells to Develop Adult T-Cell Leukemia by Maeda, Michiyuki, Tanabe-Shibuya, Junko, Miyazato, Paola, Masutani, Hiroshi, Yasunaga, Jun-Ichirou, Usami, Kazumasa, Shimizu, Akira, Matsuoka, Masao

“…T cells infected with human T-cell leukemia virus type 1 (HTLV-1) transform into malignant/leukemic cells and develop adult T-cell leukemia (ATL) after a long…”
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Dynamics and mechanisms of clonal expansion of HIV-1-infected cells in a humanized mouse model by Satou, Yorifumi, Katsuya, Hiroo, Fukuda, Asami, Misawa, Naoko, Ito, Jumpei, Uchiyama, Yoshikazu, Miyazato, Paola, Islam, Saiful, Fassati, Ariberto, Melamed, Anat, Bangham, Charles R. M., Koyanagi, Yoshio, Sato, Kei

“…Combination anti-retroviral therapy (cART) has drastically improved the clinical outcome of HIV-1 infection. Nonetheless, despite effective cART, HIV-1…”
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Versatile live-attenuated SARS-CoV-2 vaccine platform applicable to variants induces protective immunity by Yoshida, Akiho, Okamura, Shinya, Torii, Shiho, Komatsu, Sayuri, Miyazato, Paola, Sasaki, Hitomi, Ueno, Shiori, Suzuki, Hidehiko, Kamitani, Wataru, Ono, Chikako, Matsuura, Yoshiharu, Takekawa, Shiro, Yamanishi, Koichi, Ebina, Hirotaka

“…Live-attenuated vaccines are generally highly effective. Here, we aimed to develop one against SARS-CoV-2, based on the identification of three types of…”
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Correction: HTLV-1 bZIP Factor Enhances T-cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors by Kinosada, Haruka, Yasunaga, Jun-Ichirou, Shimura, Kazuya, Miyazato, Paola, Onishi, Chiho, Iyoda, Tomonori, Inaba, Kayo, Matsuoka, Masao

“…[This corrects the article DOI: 10.1371/journal.ppat.1006120.]…”
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