Search Results - "MIYAZATO, Mikiya"

Abnormal Microscopic Findings in the Placenta Correlate With the Severity of Fetal Heart Failure by Miyoshi, Takekazu, Matsuyama, Taka-aki, Nakai, Michikazu, Miyazato, Mikiya, Yoshimatsu, Jun, Hatakeyama, Kinta, Hosoda, Hiroshi

“…Background: This study investigated the association between placental pathology and fetal heart failure.Methods and Results: Singletons with a congenital heart…”
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Purification and identification of native forms of goldfish neuromedin U from brain and gut by Maruyama, Keisuke, Kaiya, Hiroyuki, Miyazato, Mikiya, Murakami, Noboru, Nakahara, Keiko, Matsuda, Kouhei

“…Neuromedin U (NMU) plays important roles in energy homeostasis in rodents and birds. Previously, our group has isolated four cDNAs encoding precursor proteins…”
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A newly developed glucagon sandwich ELISA is useful for more accurate glucagon evaluation than the currently used sandwich ELISA in subjects with elevated plasma proglucagon‐derived peptide levels by Kobayashi, Masaki, Maruyama, Nobuhiro, Yamamoto, Yukako, Togawa, Takeshi, Ida, Takanori, Yoshida, Morikatsu, Miyazato, Mikiya, Kitada, Masahisa, Hayashi, Yoshitaka, Kashiwagi, Atsunori, Kitamura, Tadahiro

“…Aims/Introduction Glucagon, a peptide hormone produced from proglucagon, is involved in the pathophysiology of diabetes. Plasma glucagon levels are currently…”
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What is the general action of ghrelin for vertebrates? – Comparisons of ghrelin’s effects across vertebrates by Kaiya, Hiroyuki, Kangawa, Kenji, Miyazato, Mikiya

“…Highlights ► Ghrelin is present in nonmammalian vertebrates, too. ► GH-releasing activity seems to be a common action of ghrelin. ► Sole action of ghrelin may…”
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Recent advances in the phylogenetic study of ghrelin by Kaiya, Hiroyuki, Miyazato, Mikiya, Kangawa, Kenji

“…► Ghrelin is a multifunctional hormone with more features than we have originally postulated. ► To understand what is ghrelin, it is also important to know the…”
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Identification and signaling characterization of four urotensin II receptor subtypes in the western clawed frog, Xenopus tropicalis by Konno, Norifumi, Takano, Moe, Miura, Koichi, Miyazato, Mikiya, Nakamachi, Tomoya, Matsuda, Kouhei, Kaiya, Hiroyuki

“…•Four functional UTR (UTR1, UTR3, UTR4, and UTR5) subtypes are present in X. tropicalis.•UTR1 and UTR5 are most likely linked to PLC/PKC and…”
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Endogenous Ghrelin Attenuates Pressure Overload–Induced Cardiac Hypertrophy via a Cholinergic Anti-Inflammatory Pathway by Mao, Yuanjie, Tokudome, Takeshi, Kishimoto, Ichiro, Otani, Kentaro, Nishimura, Hirohito, Yamaguchi, Osamu, Otsu, Kinya, Miyazato, Mikiya, Kangawa, Kenji

“…Cardiac hypertrophy, which is commonly caused by hypertension, is a major risk factor for heart failure and sudden death. Endogenous ghrelin has been shown to…”
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C-type natriuretic peptide (CNP) in endothelial cells attenuates hepatic fibrosis and inflammation in non-alcoholic steatohepatitis by Bae, Cho-Rong, Hino, Jun, Hosoda, Hiroshi, Miyazato, Mikiya, Kangawa, Kenji

“…Our previous study revealed that mice transgenic for endothelial-cell–specific overexpression of CNP (E-CNP Tg mice) are protected against the increased fat…”
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Combined evaluation of plasma B-type natriuretic peptide and urinary liver-type fatty acid-binding protein/creatinine ratio is related to worsening renal function in patients undergoing elective percutaneous coronary intervention by Yoshihara, Fumiki, Hosoda, Hiroshi, Doi, Takahito, Yoshida, Morikatsu, Kitamura, Kazuo, Yamamoto, Haruko, Asaumi, Yasuhide, Ishibashi-Ueda, Hatsue, Kishida, Masatsugu, Arisato, Tetsuya, Matsuo, Miki, Miyazato, Mikiya, Yasuda, Satoshi

“…Background There are few reports on the significance for the combined evaluation of blood humoral factors and urinary biomarkers in terms of worsening renal…”
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Luqin-like RYamide peptides regulate food-evoked responses in C. elegans by Ohno, Hayao, Yoshida, Morikatsu, Sato, Takahiro, Kato, Johji, Miyazato, Mikiya, Kojima, Masayasu, Ida, Takanori, Iino, Yuichi

“…Peptide signaling controls many processes involving coordinated actions of multiple organs, such as hormone-mediated appetite regulation. However, the extent…”
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Ghrelin: A multifunctional hormone in non-mammalian vertebrates by Kaiya, Hiroyuki, Miyazato, Mikiya, Kangawa, Kenji, Peter, Richard E., Unniappan, Suraj

“…In mammals, ghrelin is a non-amidated peptide hormone, existing in both acylated and non-acylated forms, produced mainly from the X/A or ghrelin cells present…”
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Endothelial Natriuretic Peptide Receptor 1 Play Crucial Role for Acute and Chronic Blood Pressure Regulation by Atrial Natriuretic Peptide by Tokudome, Takeshi, Otani, Kentaro, Mao, Yuanjie, Jensen, Lars Jørn, Arai, Yuji, Miyazaki, Takahiro, Sonobe, Takashi, Pearson, James T., Osaki, Tsukasa, Minamino, Naoto, Ishida, Junji, Fukamizu, Akiyoshi, Kawakami, Hayato, Onozuka, Daisuke, Nishimura, Kunihiro, Miyazato, Mikiya, Nishimura, Hirohito

“…ANP (atrial natriuretic peptide), acting through NPR1 (natriuretic peptide receptor 1), provokes hypotension. Such hypotension is thought to be due to ANP…”
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Characterization of putative tachykinin peptides in Caenorhabditis elegans by Sakai, Naoko, Ohno, Hayao, Yoshida, Morikatsu, Iwamoto, Eri, Kurogi, Akito, Jiang, Danfeng, Sato, Takahiro, Miyazato, Mikiya, Kojima, Masayasu, Kato, Johji, Ida, Takanori

“…Tachykinin-like peptides, such as substance P, neurokinin A, and neurokinin B, are among the earliest discovered and best-studied neuropeptide families, and…”
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Angiotensin II promotes pulmonary metastasis of melanoma through the activation of adhesion molecules in vascular endothelial cells by Ishikane, Shin, Hosoda, Hiroshi, Nojiri, Takashi, Tokudome, Takeshi, Mizutani, Tetsuya, Miura, Koichi, Akitake, Yoshiharu, Kimura, Toru, Imamichi, Yoshitaka, Kawabe, Shinya, Toyohira, Yumiko, Yanagihara, Nobuyuki, Takahashi-Yanaga, Fumi, Miyazato, Mikiya, Miyamoto, Kaoru, Kangawa, Kenji

“…[Display omitted] Hypertension is considered as one of the cancer progressive factors, and often found comorbidity in cancer patients. Renin-angiotensin system…”
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Atrial natriuretic peptide prevents cancer metastasis through vascular endothelial cells by Nojiri, Takashi, Hosoda, Hiroshi, Tokudome, Takeshi, Miura, Koichi, Ishikane, Shin, Otani, Kentaro, Kishimoto, Ichiro, Shintani, Yasushi, Inoue, Masayoshi, Kimura, Toru, Sawabata, Noriyoshi, Minami, Masato, Nakagiri, Tomoyuki, Funaki, Soichiro, Takeuchi, Yukiyasu, Maeda, Hajime, Kidoya, Hiroyasu, Kiyonari, Hiroshi, Shioi, Go, Arai, Yuji, Hasegawa, Takeshi, Takakura, Nobuyuki, Hori, Megumi, Ohno, Yuko, Miyazato, Mikiya, Mochizuki, Naoki, Okumura, Meinoshin, Kangawa, Kenji

“…Significance Postoperative cancer recurrence is a major problem following curative cancer surgery. Perioperative systemic inflammation induces the adhesion of…”
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Neuromedin U precursor-related peptide (NURP) exerts neuromedin U-like sympathetic nerve action in the rat by Ensho, Takuya, Maruyama, Keisuke, Mori, Kenji, Miyazato, Mikiya, Kangawa, Kenji, Nakahara, Keiko, Murakami, Noboru

“…It has been suggested that novel peptide that is produced from the neuromedin U (NMU) precursor may exist, as this precursor contains multiple consensus…”
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Moderate maternal food restriction in mice impairs physical growth, behavior, and neurodevelopment of offspring by Akitake, Yoshiharu, Katsuragi, Shinji, Hosokawa, Masato, Mishima, Kenichi, Ikeda, Tomoaki, Miyazato, Mikiya, Hosoda, Hiroshi

“…Abstract Intrauterine growth retardation (IUGR) occurs in 3% to 7% of all pregnancies. Recent human studies have indicated that neurodevelopmental…”
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Transnasal Delivery of the Peptide Agonist Specific to Neuromedin‑U Receptor 2 to the Brain for the Treatment of Obesity by Tanaka, Akiko, Takayama, Kentaro, Furubayashi, Tomoyuki, Mori, Kenji, Takemura, Yuki, Amano, Mayumi, Maeda, Chiaki, Inoue, Daisuke, Kimura, Shunsuke, Kiriyama, Akiko, Katsumi, Hidemasa, Miyazato, Mikiya, Kangawa, Kenji, Sakane, Toshiyasu, Hayashi, Yoshio, Yamamoto, Akira

“…Obesity and metabolic syndrome are threats to the health of large population worldwide as they are associated with high mortality, mainly linked to…”
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Adipocyte-specific expression of C-type natriuretic peptide suppresses lipid metabolism and adipocyte hypertrophy in adipose tissues in mice fed high-fat diet by Bae, Cho-Rong, Hino, Jun, Hosoda, Hiroshi, Son, Cheol, Makino, Hisashi, Tokudome, Takeshi, Tomita, Tsutomu, Hosoda, Kiminori, Miyazato, Mikiya, Kangawa, Kenji

“…C-type natriuretic peptide (CNP) is expressed in diverse tissues, including adipose and endothelium, and exerts its effects by binding to and activating its…”
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Deficiency of Cardiac Natriuretic Peptide Signaling Promotes Peripartum Cardiomyopathy-Like Remodeling in the Mouse Heart by Otani, Kentaro, Tokudome, Takeshi, Kamiya, Chizuko A., Mao, Yuanjie, Nishimura, Hirohito, Hasegawa, Takeshi, Arai, Yuji, Kaneko, Mari, Shioi, Go, Ishida, Junji, Fukamizu, Akiyoshi, Osaki, Tsukasa, Nagai-Okatani, Chiaki, Minamino, Naoto, Ensho, Takuya, Hino, Jun, Murata, Shunsuke, Takegami, Misa, Nishimura, Kunihiro, Kishimoto, Ichiro, Miyazato, Mikiya, Harada-Shiba, Mariko, Yoshimatsu, Jun, Nakao, Kazuwa, Ikeda, Tomoaki, Kangawa, Kenji

“…BACKGROUND:The maternal circulatory system and hormone balance both change dynamically during pregnancy, delivery, and the postpartum period. Although atrial…”
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