Search Results - "MIYAZAKI, Kohji"

Induction of hepatocyte growth factor activator gene expression under hypoxia activates the hepatocyte growth factor/c‐Met system via hypoxia inducible factor‐1 in pancreatic cancer by Kitajima, Yoshihiko, Ide, Takao, Ohtsuka, Takao, Miyazaki, Kohji

“…Hepatocyte growth facor activator (HGFA) is a serine protease that converts hepatocyte growth factor (HGF) into its active form. Our previous study…”
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Methylation-mediated gene silencing as biomarkers of gastric cancer:a review by Nakamura, Jun, Tanaka, Tomokazu, Kitajima, Yoshihiko, Noshiro, Hirokazu, Miyazaki, Kohji

“…Despite a decline in the overall incidence of gastric cancer(GC),the disease remains the second most common cause of cancer-related death worldwide and is thus…”
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Loss of ARID1A expression is related to shorter progression-free survival and chemoresistance in ovarian clear cell carcinoma by Katagiri, Atsuko, Nakayama, Kentaro, Rahman, Mohammed Tanjimur, Rahman, Munmun, Katagiri, Hiroshi, Nakayama, Naomi, Ishikawa, Masako, Ishibashi, Tomoka, Iida, Kouji, Kobayashi, Hiroshi, Otsuki, Yoshiro, Nakayama, Satoru, Miyazaki, Kohji

“…Recently, the ARID1A gene has been identified as a novel tumor suppressor in ovarian clear cell carcinoma. The prognostic significance of the loss of ARID1A…”
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Mechanisms of ovarian cancer metastasis: biochemical pathways by Nakayama, Kentaro, Nakayama, Naomi, Katagiri, Hiroshi, Miyazaki, Kohji

“…Ovarian cancer is the most lethal gynecologic malignancy. Despite advances in chemotherapy, the five-year survival rate of advanced ovarian cancer patients…”
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Evaluation of acoustic radiation force impulse elastography for fibrosis staging of chronic liver disease: a pilot study by Takahashi, Hirokazu, Ono, Naofumi, Eguchi, Yuichiro, Eguchi, Takahisa, Kitajima, Yoichiro, Kawaguchi, Yasunori, Nakashita, Shunya, Ozaki, Iwata, Mizuta, Toshihiko, Toda, Shuji, Kudo, Sho, Miyoshi, Atsushi, Miyazaki, Kohji, Fujimoto, Kazuma

“…Background: Acoustic radiation force impulse (ARFI) is a new technology integrated into conventional B‐mode ultrasonography. ARFI is used to evaluate tissue…”
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Clinicopathologic and biological analysis of PIK3CA mutation in ovarian clear cell carcinoma by Rahman, Munmun, MBBS, Nakayama, Kentaro, MD, PhD, Rahman, Mohammed Tanjimur, MBBS, Nakayama, Naomi, MD, Ishikawa, Masako, MD, PhD, Katagiri, Atsuko, MD, Iida, Kouji, BSc, Nakayama, Satoru, MD, Otsuki, Yoshiro, MD, Shih, Ie-Ming, MD, PhD, Miyazaki, Kohji, MD, PhD

“…Summary Somatic mutations of PIK3CA (phosphoinositide-3-kinase) have recently been shown playing an important role in the pathogenesis of ovarian clear cell…”
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Kisspeptin induces expression of gonadotropin-releasing hormone receptor in GnRH-producing GT1–7 cells overexpressing G protein-coupled receptor 54 by Sukhbaatar, Unurjargal, Kanasaki, Haruhiko, Mijiddorj, Tselmeg, Oride, Aki, Miyazaki, Kohji

“…Highlights • We found that kisspeptin, but not GnRH increases GnRHR promoter activity in GnRH-producing GT1–7 cells. • Kisspeptin stimulates both ERK and…”
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Clinical Significance of CEA and CA19-9 in Postoperative Follow-up of Colorectal Cancer by Yakabe, Tomomi, Nakafusa, Yuji, Sumi, Kenji, Miyoshi, Atsushi, Kitajima, Yoshihiko, Sato, Seiji, Noshiro, Hirokazu, Miyazaki, Kohji

“…Background We evaluated the efficiency of CEA and CA19-9 as tools for diagnosing recurrence in the postoperative surveillance of colorectal cancer. Materials…”
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Surface characterization of plasma-modified poly(ethylene terephthalate) film surfaces by Inagaki, Norihiro, Narushim, Kazuo, Tuchida, Norio, Miyazaki, Kohji

“…Poly(ethylene terephthalate) (PET) film surfaces were modified by argon (Ar), oxygen (O2), hydrogen (H2), nitrogen (N2), and ammonia (NH3) plasmas, and the…”
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Prognostic and therapeutic impact of the chromosome 20q13.2 ZNF217 locus amplification in ovarian clear cell carcinoma by Rahman, Mohammed Tanjimur, Nakayama, Kentaro, Rahman, Munmun, Nakayama, Naomi, Ishikawa, Masako, Katagiri, Atsuko, Iida, Kouji, Nakayama, Satoru, Otsuki, Yoshiro, Shih, Ie‐Ming, Miyazaki, Kohji

“…BACKGROUND: The goal of this study was to examine the clinical significance of ZNF217 amplification and assess whether ZNF217 could be a potential therapeutic…”
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Tumor–stromal cell interaction under hypoxia increases the invasiveness of pancreatic cancer cells through the hepatocyte growth factor/c‐Met pathway by Ide, Takao, Kitajima, Yoshihiko, Miyoshi, Atsushi, Ohtsuka, Takao, Mitsuno, Mayumi, Ohtaka, Kazuma, Koga, Yasuo, Miyazaki, Kohji

“…The hypoxic environment in tumor is reported to play an important role in pancreatic cancer progression. The interaction between stromal and cancer cells also…”
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The hypoxic environment in tumor-stromal cells accelerates pancreatic cancer progression via the activation of paracrine hepatocyte growth factor/c-Met signaling by Ide, Takao, Kitajima, Yoshihiko, Miyoshi, Atsushi, Ohtsuka, Takao, Mitsuno, Mayumi, Ohtaka, Kazuma, Miyazaki, Kohji

“…Pancreatic cancer is one of the representative solid tumors, in which the hypoxic microenvironment plays a crucial role in malignant progression. We previously…”
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Clinicopathologic analysis of loss of AT-rich interactive domain 1A expression in endometrial cancer by Rahman, Munmun, MBBS, Nakayama, Kentaro, MD, PhD, Rahman, Mohammed Tanjimur, MBBS, Katagiri, Hiroshi, MD, Katagiri, Atsuko, MD, Ishibashi, Tomoka, MD, Ishikawa, Masako, MD, PhD, Iida, Kouji, BSc, Miyazaki, Kohji, MD, PhD

“…Summary Loss of the AT-rich interactive domain 1A (a putative tumor suppressor) protein BAF250a has recently been described as a frequent event in endometrial…”
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Biological and clinical significance of NAC1 expression in cervical carcinomas: a comparative study between squamous cell carcinomas and adenocarcinomas/adenosquamous carcinomas by Yeasmin, Shamima, MD, PhD, Nakayama, Kentaro, MD, PhD, Rahman, Mohammed Tanjimur, MD, Rahman, Munmun, MD, Ishikawa, Masako, MD, PhD, Katagiri, Atsuko, MD, Iida, Kouji, MS, Nakayama, Naomi, MD, Otuski, Yoshiro, MD, PhD, Kobayashi, Hiroshi, MD, PhD, Nakayama, Satoru, MD, Miyazaki, Kohji, MD, PhD

“…Summary This study examined the biological and clinical significance of NAC1 (nucleus accumbens associated 1) expression in both cervical squamous cell…”
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Aberrant Gene Methylation Is a Biomarker for the Detection of Cancer Cells in Peritoneal Wash Samples from Advanced Gastric Cancer Patients by Hiraki, Masatsugu, Kitajima, Yoshihiko, Koga, Yasuo, Tanaka, Tomokazu, Nakamura, Jun, Hashiguchi, Kazuyoshi, Noshiro, Hirokazu, Miyazaki, Kohji

“…Purpose To assess whether gene methylation in peritoneal fluid (PF) is clinically feasible for determining micrometastasis to the peritoneum in gastric cancer…”
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KRAS and MAPK1 gene amplification in type II ovarian carcinomas by Rahman, Mohammed Tanjimur, Nakayama, Kentaro, Rahman, Munmun, Katagiri, Hiroshi, Katagiri, Atsuko, Ishibashi, Tomoka, Ishikawa, Masako, Sato, Emi, Iida, Kouji, Nakayama, Naomi, Ishikawa, Noriyuki, Miyazaki, Kohji

“…In this study, we examined the clinical significance of KRAS and MAPK1 amplification and assessed whether these amplified genes were potential therapeutic…”
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EphA4 is a prognostic factor in gastric cancer by Miyazaki, Kohji, Inokuchi, Mikito, Takagi, Yoko, Kato, Keiji, Kojima, Kazuyuki, Sugihara, Kenichi

“…Erythropoietin-producing hepatocellular (Eph) receptor, consisting of a family of receptor tyrosine kinases, plays critical roles in tumour development and is…”
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Nuclear localization signal in a cancer-related transcriptional regulator protein NAC1 by OKAZAKI, Kosuke, NAKAYAMA, Naomi, NARIAI, Yuko, NAKAYAMA, Kentaro, MIYAZAKI, Kohji, MARUYAMA, Riruke, KATO, Hiroaki, KOSUGI, Shunichi, URANO, Takeshi, SAKASHITA, Gyosuke

“…Nucleus accumbens-associated protein 1 (NAC1) might have potential oncogenic properties and participate in regulatory networks for pluripotency. Although NAC1…”
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Silencing effect of CpG island hypermethylation and histone modifications on O6-methylguanine-DNA methyltransferase ( ) gene expression in human cancer by Nakagawachi, Tetsuji, Soejima, Hidenobu, Urano, Takeshi, Zhao, Wei, Higashimoto, Ken, Satoh, Yuji, Matsukura, Shiroh, Kudo, Shinichi, Kitajima, Yoshihiko, Harada, Haruhito, Furukawa, Koichi, Matsuzaki, Hideki, Emi, Mitsuru, Nakabeppu, Yusaku, Miyazaki, Kohji, Sekiguchi, Mutsuo, Mukai, Tsunehiro

“…O6-methylguanine-DNA methyltransferase (MGMT) repairs the cytotoxic and mutagenic O6-alkylguanine produced by alkylating agents such as chemotherapeutic agents…”
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Disappearance of a uterine arteriovenous malformation following long‐term administration of oral norgestrel/ethinyl estradiol by Oride, Aki, Kanasaki, Haruhiko, Miyazaki, Kohji

“…Uterine arteriovenous malformation (AVM) can cause sudden massive hemorrhage. We report a case of uterine AVM following curettage in a patient treated…”
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