Search Results - "MIYAMOTO, Fumio"
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Dapagliflozin Reduces Fat Mass without Affecting Muscle Mass in Type 2 Diabetes
Published in Journal of Atherosclerosis and Thrombosis (01-06-2018)“…Aim: Sodium-glucose co-transporter 2 inhibitor (SGLT2i) therapy has been demonstrated to improve glycemic control and reduce body weight and fat mass in type 2…”
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The SGLT2 Inhibitor Dapagliflozin Significantly Improves the Peripheral Microvascular Endothelial Function in Patients with Uncontrolled Type 2 Diabetes Mellitus
Published in Internal Medicine (01-08-2018)“…Objective Sodium-glucose co-transporter 2 (SGLT2) inhibitors reduce cardiovascular events and decrease the body fat mass in patients with type 2 diabetes…”
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Reduced Number of Remaining or Healthy Teeth in Patients with Type 2 Diabetes Mellitus: A Cross-sectional Study Assessed by Dentists or Dental Hygienists in Japan
Published in Internal medicine (Tokyo, 1992) (01-01-2023)“…Objective This study assessed the relationships between oral health (number of remaining and healthy teeth and periodontal disease) and type 2 diabetes…”
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Elevation of the renal threshold for glucose is associated with insulin resistance and higher glycated hemoglobin levels
Published in Journal of diabetes investigation (01-05-2020)“…Aims/Introduction The renal threshold for glucose (RTg) corresponds to a blood glucose level of ~180 mg/dL; however, in hospitals, patients are often…”
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Calculated estimation of the metabolic clearance rate of insulin measured by glucose clamp examination in out-patient clinical practice
Published in Diabetology international (01-10-2024)“…Purpose A subpopulation of Japanese patients with type 2 diabetes mellitus (T2DM) who have elevated insulin clearance (IC) exists. We tested our hypothesis…”
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Severe periodontal disease in Japanese patients with high HbA1c levels: a cross-sectional study
Published in Diabetology international (01-07-2024)“…Objective This study aimed to investigate the relationship between plasma glucose profiles and periodontal disease (PD) severity in men and women Methods We…”
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Liraglutide, a Glucagon-Like Peptide-1 Analog, Increased Insulin Sensitivity Assessed by Hyperinsulinemic-Euglycemic Clamp Examination in Patients with Uncontrolled Type 2 Diabetes Mellitus
Published in Journal of diabetes research (01-01-2015)“…Aims. Glucagon-like peptide-1 (GLP-1) analog promotes insulin secretion by acting on pancreatic β-cells. This antihyperglycemic treatment for type 2 diabetes…”
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Dapagliflozin significantly reduced liver fat accumulation associated with a decrease in abdominal subcutaneous fat in patients with inadequately controlled type 2 diabetes mellitus
Published in Diabetes research and clinical practice (01-08-2018)“…We examined dapagliflozin-induced changes in liver fat accumulation. We prospectively recruited Japanese patients with inadequately controlled type 2 diabetes…”
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High frequency of defecation under metformin use may be a potential glucose-lowering factor independent of the dose-dependent effect of metformin in patients with type 2 diabetes mellitus
Published in Internal Medicine (25-10-2024)“…Objective Our previous study indicated that the efficacy of metformin in lowering glycated hemoglobin (HbA1c) levels may be influenced by the pretreatment…”
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Correlation of body muscle/fat ratio with insulin sensitivity using hyperinsulinemic-euglycemic clamp in treatment-naïve type 2 diabetes mellitus
Published in Diabetes research and clinical practice (01-10-2016)“…Highlights • Body composition assessed by InBody770 is significantly related to insulin resistance, particularly Muscle / Fat ratio. • The Muscle / Fat ratio…”
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Detection of wheat as an allergenic substance in food by a nested PCR method
Published in Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi) (01-02-2008)“…A nested PCR method was developed for the detection of DNAs extracted from allergenic substances (here, wheat) in food. Because of DNA fragmentation, detection…”
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Ratio of muscle mass to fat mass assessed by bioelectrical impedance analysis is significantly correlated with liver fat accumulation in patients with type 2 diabetes mellitus
Published in Diabetes research and clinical practice (01-05-2018)“…Obesity and ectopic fat accumulation are important conditions of type 2 diabetes mellitus (T2DM). Our aim was to determine whether bioelectrical impedance body…”
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Body muscle-to-fat ratio gender-specific cut-off values for impaired insulin sensitivity in patients with treatment-naïve type 2 diabetes mellitus
Published in Endocrine (01-12-2019)“…Purpose We previously reported that the body muscle-to-fat ratio (BMFR), measured using bioelectrical impedance, significantly correlated with whole-body…”
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Clinical usefulness of the body muscle-to-fat ratio for screening obstructive sleep apnea syndrome in patients with inadequately controlled type 2 diabetes mellitus
Published in Diabetes research and clinical practice (01-09-2018)“…To investigate whether body composition measures can be used for screening obstructive sleep apnea syndrome (OSAS) in patients with type 2 diabetes mellitus…”
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Characteristics of nephropathy in severely obese Japanese patients complicated with type 2 diabetes mellitus: a cross-sectional cohort study
Published in Endocrine (01-12-2020)“…Purpose We aimed to investigate the characteristics of kidney disease in severely obese Japanese patients with type 2 diabetes mellitus (T2DM). Methods This…”
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Clinical Factors Associated with Initial Decrease in Body-Fat Percentage Induced by Add-on Sodium-Glucose Co-transporter 2 Inhibitors in Patient with Type 2 Diabetes Mellitus
Published in Clinical drug investigation (01-01-2018)“…Background and objective Obesity is globally recognized as an important clinical problem and sodium-glucose co-transporter 2 (SGLT2) inhibitors are considered…”
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Potential Identification of Type 2 Diabetes with Elevated Insulin Clearance
Published in NEJM evidence (01-04-2022)“…BACKGROUND: Decreased blood insulin concentrations resulting from reduced pancreatic β-cell insulin secretion and elevated insulin clearance (IC) could be…”
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Body Muscle-to-Fat Ratio, Rather Than Fat-to-Muscle Ratio, Significantly Correlates With Measured Insulin Resistance in Patients With Type 2 Diabetes Mellitus
Published in Journal of clinical medicine research (01-07-2021)“…BACKGROUNDInsulin resistance (IR) assessment is important in treating type 2 diabetes mellitus (T2DM). We thus compared body muscle-to-fat ratio (BMFR) and…”
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Renoprotective Effects of Additional SGLT2 inhibitor Therapy in Patients With Type 2 Diabetes Mellitus and Chronic Kidney Disease Stages 3b-4: A Real World Report From A Japanese Specialized Diabetes Care Center
Published in Journal of clinical medicine research (01-04-2019)“…Large randomized clinical trials of patients with type 2 diabetes mellitus (T2DM) and at high risk for cardiovascular disease revealed that sodium-glucose…”
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