Search Results - "MIYAMOTO, AKIO"

The impact of calcitriol and estradiol on the SARS-CoV-2 biological activity: a molecular modeling approach by Mansouri, Alireza, Kowsar, Rasoul, Zakariazadeh, Mostafa, Hakimi, Hassan, Miyamoto, Akio

“…The novel coronavirus disease (COVID-19) is currently a big concern around the world. Recent reports show that the disease severity and mortality of COVID-19…”
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Understanding the hidden relations between pro- and anti-inflammatory cytokine genes in bovine oviduct epithelium using a multilayer response surface method by Kowsar, Rasoul, Keshtegar, Behrooz, Miyamoto, Akio

“…An understanding gene-gene interaction helps users to design the next experiments efficiently and (if applicable) to make a better decision of drugs…”
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Homology Modeling, Molecular Dynamics Simulation, and Prediction of Bovine TLR2 Heterodimerization by Mansouri, Alireza, Yousef, Mohamed Samy, Kowsar, Rasoul, Miyamoto, Akio

“…Toll-like receptor 2 (TLR2) is a major membrane-bound receptor with ligand and species specificity that activates the host immune response. Heterodimerization…”
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Epidermal growth factor alleviates the negative impact of urea on frozen-thawed bovine sperm, but the subsequent developmental competence is compromised by Kowsar, Rasoul, Ronasi, Shahrzad, Sadeghi, Nima, Sadeghi, Khaled, Miyamoto, Akio

“…Upon insemination, sperm cells are exposed to components of the female reproductive tract (FRT) fluids, such as urea and epidermal growth factor (EGF). It has…”
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Bone morphogenetic protein (BMP)-4 and BMP-7 suppress granulosa cell apoptosis via different pathways: BMP-4 via PI3K/PDK-1/Akt and BMP-7 via PI3K/PDK-1/PKC by Shimizu, Takashi, Kayamori, Takefumi, Murayama, Chiaki, Miyamoto, Akio

“…► BMP-4 suppresses granulosa cell apoptosis via PI3K/PDK-1/PKC pathway. ► BMP-7 suppressed granulosa cell apoptosis via PI3K/PDK-1/Akt pathway. ► BMP-4 and…”
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Sperm induce proinflammatory responses in the uterus and peripheral blood immune cells of artificially inseminated cows by MAREY, Mohamed A., MA, Dongxue, YOSHINO, Hitomi, ELESH, Ibrahim F., ZINNAH, Mohammad A., FIORENZA, Mariani F., MORIYASU, Satoru, MIYAMOTO, Akio

“…This in vivo study aimed to investigate local and systemic immune responses induced by sperm in cows after artificial insemination (AI). Initially, 12…”
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Sperm activate TLR2/TLR1 heterodimerization to induce a weak proinflammatory response in the bovine uterus by Mansouri, Alireza, Yousef, Mohamed Samy, Kowsar, Rasoul, Usui, Nonoka, Akthar, Ihshan, Miyamoto, Akio

“…Toll-like receptor 2 (TLR2) signaling pathway is involved in the sperm-triggered uterine inflammatory response at insemination, but its precise mechanism at…”
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Possible role of interferon tau on the bovine corpus luteum and neutrophils during the early pregnancy by Shirasuna, Koumei, Matsumoto, Haruka, Matsuyama, Shuichi, Kimura, Koji, Bollwein, Heinrich, Miyamoto, Akio

“…When pregnancy is established, interferon tau (IFNT), a well-known pregnancy recognition signal in ruminants, is secreted by embryonic trophoblast cells and…”
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Innate immunity and inflammation of the bovine female reproductive tract in health and disease by Sheldon, I Martin, Cronin, James G, Healey, Gareth D, Gabler, Christoph, Heuwieser, Wolfgang, Streyl, Dominik, Bromfield, John J, Miyamoto, Akio, Fergani, Chrys, Dobson, Hilary

“…Mammalian reproductive physiology and the development of viviparity co-evolved with inflammation and immunity over millennia. Many inflammatory mediators…”
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TLR2/4 signaling pathway mediates sperm-induced inflammation in bovine endometrial epithelial cells in vitro by Ezz, Mohamed Aboul, Marey, Mohamed Ali, Elweza, Ahmed Essam, Kawai, Tomoko, Heppelmann, Maike, Pfarrer, Christiane, Balboula, Ahmed Zaky, Montaser, Abdelmonem, Imakawa, Kazuhiko, Zaabel, Samy Moawad, Shimada, Masayuki, Miyamoto, Akio

“…We have recently shown that sperm attachment to bovine endometrial epithelial cells (BEECs) triggers uterine local innate immunity with induction of a…”
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Lipopolysaccharide (LPS) Inhibits Steroid Production in Theca Cells of Bovine Follicles In Vitro: Distinct Effect of LPS on Theca Cell Function in Pre- and Post-selection Follicles by MAGATA, Fumie, HORIUCHI, Maya, MIYAMOTO, Akio, SHIMIZU, Takashi

“…In postpartum dairy cows, lipopolysaccharide (LPS) derived from gram-negative bacteria such as Escherichia coli causes uterine inflammation and leads to…”
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A multilevel analysis identifies the different relationships between amino acids and the competence of oocytes matured individually or in groups by Kowsar, Rasoul, Mansouri, Alireza, Sadeghi, Nima, Abadi, Mohammad Heidaran Ali, Ghoreishi, Seyed Mehdi, Sadeghi, Khaled, Miyamoto, Akio

“…High-protein diets contribute to an increase in urea follicular concentrations associated with decreased fertility. Urea has been shown to interfere with the…”
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Sperm enter glands of preovulatory bovine endometrial explants and initiate inflammation by Akthar, Ihshan, Suarez, Susan S, Morillo, Vernadyn A, Sasaki, Motoki, Ezz, Mohamed A, Takahashi, Ken-ichi, Shimada, Masayuki, Marey, Mohamed A, Miyamoto, Akio

“…We previously reported that sperm binding to cultured monolayers of bovine uterine epithelial cells induces an acute inflammatory response involving the…”
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Roadmap to pregnancy in the first 7 days post-insemination in the cow: Immune crosstalk in the corpus luteum, oviduct, and uterus by Talukder, Anup K., Marey, Mohamed A., Shirasuna, Koumei, Kusama, Kazuya, Shimada, Masayuki, Imakawa, Kazuhiko, Miyamoto, Akio

“…The first 7 days post-insemination are critical for establishment of pregnancy. The pre-ovulatory luteinizing hormone (LH) surge induces ovulation through…”
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Sperm Binding to Oviduct Epithelial Cells Enhances TGFB1 and IL10 Expressions in Epithelial Cells as Well as Neutrophils In Vitro: Prostaglandin E2 As a Main Regulator of Anti-Inflammatory Response in the Bovine Oviduct by Yousef, Mohamed Samy, Marey, Mohamed Ali, Hambruch, Nina, Hayakawa, Hiroyuki, Shimizu, Takashi, Hussien, Hassan Ali, Abdel-Razek, Abdel-Razek Khalifa, Pfarrer, Christiane, Miyamoto, Akio

“…Sperm are allogenic to the female genital tract; however, oviducts provide optimal conditions for survival and capacitation of these non-self cells until…”
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Bovine embryo induces an anti-inflammatory response in uterine epithelial cells and immune cells in vitro: possible involvement of interferon tau as an intermediator by TALUKDER, Anup K., YOUSEF, Mohamed S., RASHID, Mohammad B., AWAI, Kensuke, ACOSTA, Tomas J., SHIMIZU, Takashi, OKUDA, Kiyoshi, SHIMADA, Masayuki, IMAKAWA, Kazuhiko, MIYAMOTO, Akio

“…Recent observations suggest that the bovine uterus starts to react to the early embryo immediately after its arrival from the oviduct. The present study aimed…”
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Hyaluronan regulates sperm-induced inflammatory response by enhancing sperm attachment to bovine endometrial epithelial cells via CD44: in-silico and in-vitro approaches by Ezz, Mohamed Aboul, Mansouri, Alireza, Akthar, Ihshan, Yousef, Mohamed Samy, Kowsar, Rasoul, Miyamoto, Akio

“…Recently, we reported that sperm induce cluster of differentiation 44 (CD44) expression and Toll-like receptor 2 (TLR2)-mediated inflammatory response in…”
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A proinflammatory response of bovine endometrial epithelial cells to active sperm in vitro by Elweza, Ahmed E., Ezz, Mohamed A., Acosta, Tomas J., Talukder, Anup K., Shimizu, Takashi, Hayakawa, Hiroyuki, Shimada, Masayuki, Imakawa, Kazuhiko, Zaghloul, Ahmed H., Miyamoto, Akio

“…In the cow, cryopreserved semen is inseminated into the uterus, and most of sperm are removed by backflow and phagocytes. Nevertheless, the mechanism…”
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Progesterone and Inflammatory Response in the Oviduct during Physiological and Pathological Conditions by McGlade, Emily A, Miyamoto, Akio, Winuthayanon, Wipawee

“…Progesterone has been shown to be a potent suppressor of several inflammatory pathways. During pregnancy, progesterone levels increase, allowing for normal…”
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Ovulatory follicular fluid induces sperm phagocytosis by neutrophils, but oviductal fluid around oestrus suppresses its inflammatory effect in the buffalo oviduct in vitro by Yousef, Mohamed S., Abd‐Elhafeez, Hanan H., Talukder, Anup K., Miyamoto, Akio

“…We have recently shown that the conditioned media from bovine oviductal epithelial cell culture suppress sperm phagocytosis by neutrophils, suggesting that the…”
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