Search Results - "MITTLER, Uwe"

von Willebrand Factor–Cleaving Protease in Thrombotic Thrombocytopenic Purpura and the Hemolytic–Uremic Syndrome by Furlan, Miha, Robles, Rodolfo, Galbusera, Miriam, Remuzzi, Giuseppe, Kyrle, Paul A, Brenner, Brigitte, Krause, Manuela, Scharrer, Inge, Aumann, Volker, Mittler, Uwe, Solenthaler, Max, Lämmle, Bernhard

“…Thrombotic thrombocytopenic purpura, a disseminated thrombotic microangiopathy, was initially described by Moschcowitz in 1924. 1 Three decades later, Gasser…”
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Prognostic Relevance of Clinical and Biological Risk Factors in Childhood Medulloblastoma: Results of Patients Treated in the Prospective Multicenter Trial HIT'91 by RUTKOWSKI, Stefan, VON BUEREN, André, MITTLER, Uwe, URBAN, Christian, BENESCH, Martin, KORTMANN, Rolf D, SCHLEGEL, Paul G, KUEHL, Joachim, PIETSCH, Torsten, GROTZER, Michael, HOFF, Katjavon, HARTMANN, Wolfgang, SHALABY, Tarek, DEINLEIN, Frank, WARMUTH-METZ, Monika, SOERENSEN, Niels, EMSER, Angela, BODE, Udo

“…Purpose: To identify better risk stratification systems in childhood medulloblastoma based on clinical factors and analysis of routinely processed…”
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Postoperative neoadjuvant chemotherapy before radiotherapy as compared to immediate radiotherapy followed by maintenance chemotherapy in the treatment of medulloblastoma in childhood: results of the German prospective randomized trial HIT '91 by Kortmann, R D, Kühl, J, Timmermann, B, Mittler, U, Urban, C, Budach, V, Richter, E, Willich, N, Flentje, M, Berthold, F, Slavc, I, Wolff, J, Meisner, C, Wiestler, O, Sörensen, N, Warmuth-Metz, M, Bamberg, M

“…The German Society of Pediatric Hematology and Oncology (GPOH) conducted a randomized, prospective, multicenter trial (HIT '91) in order to improve the…”
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Familial clustering of Langerhans cell histiocytosis by Aricò, Maurizio, Nichols, Kim, Whitlock, James A., Arceci, Robert, Haupt, Riccardo, Mittler, Uwe, Kühne, Thomas, Lombardi, Alessandra, Ishii, Eiichi, Egeler, R. Maarten, Danesino, Cesare

“…Langerhans cell histiocytosis (LCH) is considered a non‐hereditary disorder. Evaluation of the few familial cases might provide insight into its aetiology and…”
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Unusual endocrine pancreatic carcinoma (carcinoid tumor) in a 14‐year‐old girl by Lenze, Stefanie, Aumann, Volker, Kluba, Ute, Wagemann, Winfried, Evert, Matthias, Mittler, Uwe, Vorwerk, Peter

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Insulin-like growth factor-binding protein 4 in children with acute lymphoblastic leukemia by WEX, Heike, AHRENS, Dörte, HOHMANN, Bianka, REDLICH, Antje, MITTLER, Uwe, VORWERK, Peter

“…Insulin-like growth factor-binding protein 4 (IGFBP-4) is a potent inhibitor of IGF-mediated cell proliferation. To investigate the functional relevance of…”
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Plasma leptin and leptin receptor expression in childhood acute lymphoblastic leukemia by WEX, Heike, PONELIS, Edita, WEX, Thomas, DRESSENDÖRFER, Regina, MITTLER, Uwe, VORWERK, Peter

“…Recently, leptin has been shown to play a regulatory role for differentiation within the myeloid and erythroid cell lineage, whereas results of its regulatory…”
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Long-term outcome and clinical prognostic factors in children with medulloblastoma treated in the prospective randomised multicentre trial HIT'91 by VON HOFF, Katja, HINKES, Bernward, GOETTE, Heiko, SCHLEGEL, Paul G, PIETSCH, Torsten, KORTMANN, Rolf D, KUEHL, Joachim, RUTKOWSKI, Stefan, GERBER, Nicolas U, DEINLEIN, Frank, MITTLER, Uwe, URBAN, Christian, BENESCH, Martin, WARMUTH-METZ, Monika, SOERENSEN, Niels, ZWIENER, Isabella

“…To analyse long-term outcome and clinical prognostic factors in medulloblastoma. We analysed 280 patients with medulloblastoma (3-18 years) included from 1991…”
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p53 and ras Mutations in Ewing's Sarcoma by Radig, Kathrin, Schneider-Stock, Regine, Röse, Ingeborg, Mittler, Uwe, Oda, Yoshinao, Roessner, Albert

“…The role of tumor suppresser genes and oncogenes in the development of Ewing's sarcoma has not yet been fully clarified. In this study, we analyzed the…”
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A long duration of the prediagnostic symptomatic interval is not associated with an unfavourable prognosis in childhood medulloblastoma by Gerber, Nicolas U, von Hoff, Katja, von Bueren, André O, Treulieb, Wiebke, Deinlein, Frank, Benesch, Martin, Zwiener, Isabella, Soerensen, Niels, Warmuth-Metz, Monika, Pietsch, Torsten, Mittler, Uwe, Kuehl, Joachim, Kortmann, Rolf-Dieter, Grotzer, Michael A, Rutkowski, Stefan

“…Abstract Background Due to the lacking specificity of symptoms making a correct diagnosis can be a challenge in children with medulloblastoma. This can lead to…”
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Childhood pineoblastoma: experiences from the prospective multicenter trials HIT-SKK87, HIT-SKK92 and HIT91 by Hinkes, Bernward G, von Hoff, Katja, Deinlein, Frank, Warmuth-Metz, Monika, Soerensen, Niels, Timmermann, Beate, Mittler, Uwe, Urban, Christian, Bode, Udo, Pietsch, Torsten, Schlegel, Paul G, Kortmann, Rolf D, Kuehl, Joachim, Rutkowski, Stefan

“…To analyze the outcome of children with pineoblastoma (PB), treated within the prospective multicenter trials HIT-SKK87, HIT-SKK92 and HIT91 of German-speaking…”
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Insulin-Like Growth Factor Binding Protein-2 at Diagnosis of Childhood Acute Lymphoblastic Leukemia and the Prediction of Relapse Risk by Vorwerk, Peter, Mohnike, Klaus, Wex, Heike, Röhl, Friedrich-Wilhelm, Zimmermann, Martin, Blum, Werner F., Mittler, Uwe

“…Despite remarkable advances in the clinical outcome of most children with acute lymphoblastic leukemia, a substantial number of patients ultimately relapse or…”
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Near‐total splenectomy for hereditary spherocytosis: clinical prospects in relation to disease severity by Stoehr, Gerhard A., Sobh, Julian N., Luecken, Jan, Heidemann, Kathrin, Mittler, Uwe, Hilgers, Reinhard, Eber, Stefan W.

“…Summary We prospectively studied the efficacy of near total splenectomy (NTS) for managing hereditary spherocytosis (HS) based on haemoglobin (Hb), total…”
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P-32 EXPRESSION OF A PUTATIVE IGFBP-3 RECEPTOR IN MNC OF PATIENTS WITH MALIGNANT DISEASES by Vorwerk, Peter, Redlich, Antje, Bernheiden, Martin, Oh, Youngman, Mittler, Uwe

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Long-term outcome and clinical prognostic factors in children with medulloblastoma treated in the prospective randomised multicentre trial HIT‘91 by Hoff, Katja von, Hinkes, Bernward, Gerber, Nicolas U, Deinlein, Frank, Mittler, Uwe, Urban, Christian, Benesch, Martin, Warmuth-Metz, Monika, Soerensen, Niels, Zwiener, Isabella, Goette, Heiko, Schlegel, Paul G, Pietsch, Torsten, Kortmann, Rolf D, Kuehl, Joachim, Rutkowski, Stefan

“…Abstract Purpose To analyse long-term outcome and clinical prognostic factors in medulloblastoma. Methods We analysed 280 patients with medulloblastoma (3–18…”
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short report: Near-total splenectomy for hereditary spherocytosis: clinical prospects in relation to disease severity by Stoehr, Gerhard A, Sobh, Julian N, Luecken, Jan, Heidemann, Kathrin, Mittler, Uwe, Hilgers, Reinhard, Eber, Stefan W

“…We prospectively studied the efficacy of near total splenectomy (NTS) for managing hereditary spherocytosis (HS) based on haemoglobin (Hb), total bilirubin and…”
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Loss of imprinting of IGF-II gene in children with acute lymphoblastic leukemia by Vorwerk, Peter, Wex, Heike, Bessert, Cornelia, Hohmann, Bianka, Schmidt, Uwe, Mittler, Uwe

“…Insulin-like growth factor-II (IGF-II) is known to be involved in the regulation of growth, differentiation and cell death in normal human tissues. In a…”
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Chronic natural killer cell lymphocytosis is associated with elevated cytotoxic activity of natural killer cells by Wex, Heike, Aumann, Volker, Häusler, Martin, Vorwerk, Peter, Mittler, Uwe

“…The authors describe a 16-year-old girl who has suffered from chronic natural killer cell lymphocytosis (CNKL) for 12 years. From age 4 years, she has shown a…”
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Genetic heterogeneity of severe von Willebrand disease type III in the German population by Schneppenheim, R, Krey, S, Bergmann, F, Bock, D, Budde, U, Lange, M, Linde, R, Mittler, U, Meili, E, Mertes, G

“…The genetic heterogeneity of severe von Willebrand disease (vWd) type III was estimated by analysing extended haplotypes of eleven intragenic restriction…”
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Gliomatosis cerebri: post-mortem molecular and immunohistochemical analyses in a case treated with thalidomide by MAWRIN, Christian, AUMANN, Volker, KIRCHES, Elmar, SCHNEIDER-STOCK, Regine, SCHERLACH, Cordula, VOGEL, Siegfried, MITTLER, Uwe, DIETZMANN, Knut, KRAUSE, Guido, WEIS, Serge

“…Gliomatosis cerebri (GC) is a rare tumor of the central nervous system (CNS) characterized by widespread diffuse infiltration of the brain and spinal cord by…”
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