Search Results - "MITSUI, Hiroshi"

Progressive activation of TH2/TH22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis by Gittler, Julia K., Shemer, Avner, Suárez-Fariñas, Mayte, Fuentes-Duculan, Judilyn, Gulewicz, Kara J., Wang, Claire Q.F., Mitsui, Hiroshi, Cardinale, Irma, de Guzman Strong, Cristina, Krueger, James G., Guttman-Yassky, Emma

“…Atopic dermatitis (AD) is a common disease with an increasing prevalence. The primary pathogenesis of the disease is still elusive, resulting in the lack of…”
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Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection by Esaki, Hitokazu, MD, Ewald, David A., MSc, Ungar, Benjamin, BA, Rozenblit, Mariya, BA, Zheng, Xiuzhong, MSc, Xu, Hui, MSc, Estrada, Yeriel D., BS, Peng, Xiangyu, MSc, Mitsui, Hiroshi, MD, PhD, Litman, Thomas, PhD, Suárez-Fariñas, Mayte, PhD, Krueger, James G., MD, PhD, Guttman-Yassky, Emma, MD, PhD

“…Background The molecular signature of atopic dermatitis (AD) lesions is associated with TH 2 and TH 22 activation and epidermal alterations. However, the…”
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IL-17 and TNF Synergistically Modulate Cytokine Expression while Suppressing Melanogenesis: Potential Relevance to Psoriasis by Wang, Claire Q.F., Akalu, Yemsratch T., Suarez-Farinas, Mayte, Gonzalez, Juana, Mitsui, Hiroshi, Lowes, Michelle A., Orlow, Seth J., Manga, Prashiela, Krueger, James G.

“…Inflammation-associated pigmentation changes are extremely common, but the etiology underlying this clinical observation remains elusive. Particularly, it is…”
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Pancreaticoduodenal Artery Aneurysm Rupture Presenting as Duodenal Obstruction Successfully Treated with Early Transcatheter Arterial Embolization: A Case Report of Suspected Segmental Arterial Mediolysis by Ishihara, Tatsuhiko, Matsui, Toru, Katoh, Tomoji, Kobayashi, Katsuya, Sekigawa, Kenichiro, Suzuki, Takeo, Mitsui, Hiroshi

“…Visceral aneurysms are a rare but important form of abdominal vascular disease. Rupture of the aneurysms leads to serious symptoms, such as acute abdomen or…”
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Comparative Genomic Profiling of Synovium Versus Skin Lesions in Psoriatic Arthritis by Belasco, Jennifer, Louie, James S., Gulati, Nicholas, Wei, Nathan, Nograles, Kristine, Fuentes‐Duculan, Judilyn, Mitsui, Hiroshi, Suárez‐Fariñas, Mayte, Krueger, James G.

“…Objective To our knowledge, there is no broad genomic analysis comparing skin and synovium in psoriatic arthritis (PsA). Also, there is little understanding of…”
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IL-17 induces an expanded range of downstream genes in reconstituted human epidermis model by Chiricozzi, Andrea, Nograles, Kristine E, Johnson-Huang, Leanne M, Fuentes-Duculan, Judilyn, Cardinale, Irma, Bonifacio, Kathleen M, Gulati, Nicholas, Mitsui, Hiroshi, Guttman-Yassky, Emma, Suárez-Fariñas, Mayte, Krueger, James G

“…IL-17 is the defining cytokine of the Th17, Tc17, and γδ T cell populations that plays a critical role in mediating inflammation and autoimmunity. Psoriasis…”
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A Subpopulation of CD163-Positive Macrophages Is Classically Activated in Psoriasis by Fuentes-Duculan, Judilyn, Suárez-Fariñas, Mayte, Zaba, Lisa C., Nograles, Kristine E., Pierson, Katherine C., Mitsui, Hiroshi, Pensabene, Cara A., Kzhyshkowska, Julia, Krueger, James G., Lowes, Michelle A.

“…Macrophages are important cells of the innate immune system, and their study is essential to gain greater understanding of the inflammatory nature of…”
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Case of bullous pemphigoid refractory to corticosteroids by antiepileptic drug‐induced CYP3A4 by Asakawa, Riko, Ogawa, Youichi, Maejima, Eri, Honobe‐Tabuchi, Akiko, Okamoto, Takashi, Mitsui, Hiroshi, Kagawa, Yoshiyuki, Shimada, Shinji, Kawamura, Tatsuyoshi

“…The most common treatment option for patients with bullous pemphigoid is systemic corticosteroids. CYP3A4, a drug‐metabolizing enzyme in the liver, metabolizes…”
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Case of CIC‐DUX4 sarcoma of the skin: Histological simulant of epithelioid angiosarcoma by Maejima, Eri, Mitsui, Hiroshi, Ohnuma, Takehiro, Oishi, Naoki, Odate, Toru, Deguchi, Nobuhiro, Inozume, Takashi, Ogawa, Youichi, Shimada, Shinji, Kondo, Tetsuo, Kawamura, Tatsuyoshi

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Multiple bullous pilomatricomas in a patient with Rubinstein–Taybi syndrome by Minai, Lisa, Yagasaki, Hideaki, Ogawa, Youichi, Deguchi, Nobuhiro, Mitsui, Hiroshi, Shimada, Shinji, Kawamura, Tatsuyoshi

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Case of linear immunoglobulin A bullous dermatosis in a patient with prostate cancer by Mitsui, Hiroshi, Tanaka, Keiko, Okamoto, Takashi, Ogawa, Youichi, Shimada, Shinji, Kawamura, Tatsuyoshi

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Human Keratinocytes' Response to Injury Upregulates CCL20 and Other Genes Linking Innate and Adaptive Immunity by Kennedy-Crispin, Milène, Billick, Erika, Mitsui, Hiroshi, Gulati, Nicholas, Fujita, Hideki, Gilleaudeau, Patricia, Sullivan-Whalen, Mary, Johnson-Huang, Leanne M., Suárez-Fariñas, Mayte, Krueger, James G.

“…In the early stages of wound healing, keratinocytes (KCs) become “activated” and release inflammatory molecules such as IL-1 and IL-8, which are linked to…”
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Traditional serrated adenoma with superficially serrated adenoma: A case treated with endoscopic submucosal dissection with detailed endoscopic observation and pathological study by Sato, Momoka, Kato, Tomoji, Tezen, Yu, Hayashi, Takeshi, Matsui, Toru, Kobayashi, Katsuya, Sekigawa, Kenichiro, Tajiri, Ryosuke, Mitsui, Hiroshi

“…A new subtype of serrated lesions, superficially serrated adenoma (SuSA), has been proposed as a lesion that histopathologically exhibits the morphological…”
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Prenatal Torsion of Radial Polydactyly: A Gangrenous Mass at the Base of the Thumb by Watanabe, Daisuke, Hasebe, Yohei, Mitsui, Hiroshi, Oishi, Naoki, Kasai, Shin, Akahane, Koshi, Kojika, Satoru, Inukai, Takeshi

“…A patient was born with a mass at the base of the thumb approximately 1.5 cm in diameter on the radial side of the fingers. The mass had globular swelling…”
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Case of cutaneous sarcoidosis treated with delgocitinib 0.5% ointment by Muto, Yoshinori, Mitsui, Hiroshi, Ogawa, Youichi, Deguchi, Nobuhiro, Shimada, Shinji, Kawamura, Tatsuyoshi

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Combined Use of Laser Capture Microdissection and cDNA Microarray Analysis Identifies Locally Expressed Disease-Related Genes in Focal Regions of Psoriasis Vulgaris Skin Lesions by Mitsui, Hiroshi, Suárez-Fariñas, Mayte, Belkin, Daniel A., Levenkova, Natasha, Fuentes-Duculan, Judilyn, Coats, Israel, Fujita, Hideki, Krueger, James G.

“…Psoriasis vulgaris is a complex disease characterized by alterations in growth and differentiation of epidermal keratinocytes, as well as a marked increase in…”
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Case of trigeminal trophic syndrome secondary to endovascular treatment for internal carotid artery aneurysm by Minai, Lisa, Ogawa, Youichi, Kinoshita, Manao, Ito, Hidemichi, Kume, Miki, Mitsui, Hiroshi, Shimada, Shinji, Kawamura, Tatsuyoshi

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Pyoderma gangrenosum associated with ulcerative colitis: A recalcitrant case responded to adalimumab with granulocyte and monocyte adsorption apheresis by Isami, Yuki, Kawase, Yuriko, Kondo, Akari, Akita, Wataru, Yasuda, Koji, Matsutani, Takeshi, Mitsui, Hiroshi

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Development of pemphigus vegetans and exacerbation of pemphigus foliaceus after secukinumab loading in a patient with complicated generalized pustular psoriasis and pyoderma gangrenosum by Minai, Lisa, Takeichi, Takuya, Ogawa, Youichi, Honobe‐Tabuchi, Akiko, Okamoto, Takashi, Mitsui, Hiroshi, Shimada, Shinji, Akiyama, Masashi, Kawamura, Tatsuyoshi

“…In dermatology, biologics that block signaling pathways of TNF‐α, IL‐4/IL13, IL‐17s, and IL‐23 are widely used for the treatment of several inflammatory skin…”
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Increased Tc22 and Treg/CD8 ratio contribute to aggressive growth of transplant associated squamous cell carcinoma by Zhang, Shali, Fujita, Hideki, Mitsui, Hiroshi, Yanofsky, Valerie R, Fuentes-Duculan, Judilyn, Pettersen, Julia S, Suárez-Fariñas, Mayte, Gonzalez, Juana, Wang, Claire Q F, Krueger, James G, Felsen, Diane, Carucci, John A

“…Immune suppressed organ transplant recipients suffer increased morbidity and mortality from primary cutaneous SCC. We studied tumor microenvironment in…”
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