Search Results - "MITAS, Michael"

EpCAM is overexpressed in breast cancer and is a potential target for breast cancer gene therapy by OSTA, Walid A, YIAN CHEN, MIKHITARIAN, Kaidi, MITAS, Michael, SALEM, Mohamed, HANNUN, Yusuf A, COLE, David J, GILLANDERS, William E

“…EpCAM (epithelial cell adhesion molecule) is a cell surface molecule that is known to be highly expressed in colon and other epithelial carcinomas. EpCAM is…”
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Accurate discrimination of pancreatic ductal adenocarcinoma and chronic pancreatitis using multimarker expression data and samples obtained by minimally invasive fine needle aspiration by Chen, Yian, Zheng, Bin, Robbins, David H., Lewin, David N., Mikhitarian, Kaidi, Graham, Amanda, Rumpp, Laurrie, Glenn, Tammy, Gillanders, William E., Cole, David J., Lu, Xinghua, Hoffman, Brenda J., Mitas, Michael

“…To augment cytological diagnosis of pancreatic ductal adenocarcinoma (PDAC) in tissue samples obtained by minimally invasive endoscopic ultrasound‐guided fine…”
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Quantitative real‐time RT‐PCR detection of breast cancer micrometastasis using a multigene marker panel by Mitas, Michael, Mikhitarian, Kaidi, Walters, Christian, Baron, Paul L., Elliott, Bruce M., Brothers, Thomas E., Robison, Jay G., Metcalf, John S., Palesch, Yuko Y., Zhang, Zhen, Gillanders, William E., Cole, David J.

“…Real‐time RT‐PCR is a relatively new technology that uses an online fluorescence detection system to determine gene expression levels. It has the potential to…”
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Accurate molecular detection of non-small cell lung cancer metastases in mediastinal lymph nodes sampled by endoscopic ultrasound-guided needle aspiration by Wallace, Michael B, Block, Mark I, Gillanders, William, Ravenel, James, Hoffman, Brenda J, Reed, Carolyn E, Fraig, Mostafa, Cole, David, Mitas, Michael

“…The recurrence of disease after the complete resection of early stage non-small cell lung cancer (NSCLC) indicates that undetected metastases were present at…”
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Detection of mammaglobin mRNA in peripheral blood is associated with high grade breast cancer: interim results of a prospective cohort study by Mikhitarian, Kaidi, Martin, Renee Hebert, Ruppel, Megan Baker, Gillanders, William E, Hoda, Rana, Schutte, Del H, Callahan, Kathi, Mitas, Michael, Cole, David J

“…We sought to examine the detection rate of cancer cells in peripheral blood (PBL) and in bone marrow (BM) using an established 7-gene marker panel and…”
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Molecular Detection of Breast Cancer Cells in the Peripheral Blood of Advanced-Stage Breast Cancer Patients Using Multimarker Real-Time Reverse Transcription-Polymerase Chain Reaction and a Novel Porous Barrier Density Gradient Centrifugation Technology by Baker, Megan K, Mikhitarian, Kaidi, Osta, Walid, Callahan, Kathi, Hoda, Rana, Brescia, Frank, Kneuper-Hall, Rayna, Mitas, Michael, Cole, David J, Gillanders, William E

“…Purpose: The goal of this study was to develop a molecular diagnostic assay to detect circulating breast cancer cells in the peripheral blood for the purpose…”
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A simple two-gene prognostic model for adenocarcinoma of the lung by Reed, Carolyn E., MD, Graham, Amanda, MS, Hoda, Rana S., MD, Khoor, Andras, MD, Garrett-Mayer, Elizabeth, PhD, Wallace, Michael B., MD, Mitas, Michael, PhD

“…Objective We hypothesized that clinical outcome of resected early-stage adenocarcinoma of the lung can be predicted by the expression of a few critically…”
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An Innovative Microarray Strategy Identities Informative Molecular Markers for the Detection of Micrometastatic Breast Cancer by MIKHITARIAN, Kaidi, GILLANDERS, William E, ALMEIDA, Jonas S, MARTIN, Renee Hebert, VARELA, Juan C, METCALF, John S, COLE, David J, MITAS, Michael

“…There is increasing evidence that molecular detection of micrometastatic breast cancer in the axillary lymph nodes (ALN) of breast cancer patients can improve…”
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Detection of circulating tumor cells in the peripheral blood of patients with androgen‐independent, advanced or metastatic prostate cancer by Mitas, Michael C., Chaudhary, Uzair B., Marshall, David T., Gattoni‐Celli, Sebastiano

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Accurate Discrimination of Barrett's Esophagus and Esophageal Adenocarcinoma Using a Quantitative Three-Tiered Algorithm and Multimarker Real-time Reverse Transcription-PCR by MITAS, Michael, ALMEIDA, Jonas S, COLE, David J, HAWES, Robert, REED, Carolyn E, HOFFMAN, Brenda J, MIKHITARIAN, Kaidi, GILLANDERS, William E, LEWIN, David N, SPYROPOULOS, Demetri D, HOOVER, Loretta, GRAHAM, Amanda, GLENN, Tammy, KING, Peter

“…Esophageal adenocarcinoma (EA) is increasing faster than any other cancer in the U.S. In this report, we first show that EA can be distinguished from normal…”
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Hairpin properties of single-stranded DNA containing a GC-rich triplet repeat: (CTG)15 by Mitas, Michael, Yu, Adong, Dill, Jeffrey, Kamp, Timothy J., Chambers, Eric J., Haworth, Ian S.

“…ABSTRACT Although triplet repeat DNA sequences are scattered throughout the human genome, their biological function remains obscure. To aid in correlating…”
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Enhanced detection of RNA from paraffin-embedded tissue using a panel of truncated gene-specific primers for reverse transcription by Mikhitarian, Kaidi, Reott, Steve, Hoover, Loretta, Allen, Ann, Cole, David J, Gillanders, William E, Mitas, Michael

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At Physiological pH, d(CCG)15 Forms a Hairpin Containing Protonated Cytosines and a Distorted Helix by Yu, Adong, Barron, Maria D, Romero, Rebecca M, Christy, Mellisa, Gold, Barry, Dai, Jianli, Gray, Donald M, Haworth, Ian S, Mitas, Michael

“…To investigate potential structures of d(CGG/CCG) n that might relate to their biological function and association with triplet repeat expansion diseases…”
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ZEB1-responsive genes in non-small cell lung cancer by Gemmill, Robert M, Roche, Joëlle, Potiron, Vincent A, Nasarre, Patrick, Mitas, Michael, Coldren, Chris D, Helfrich, Barbara A, Garrett-Mayer, Elizabeth, Bunn, Paul A, Drabkin, Harry A

“…Abstract The epithelial to mesenchymal transition (EMT) is a developmental process enabling epithelial cells to gain a migratory mesenchymal phenotype. In…”
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Trinucleotide repeats associated with human disease by Mitas, M

“…Triplet repeat expansion diseases (TREDs) are characterized by the coincidence of disease manifestation with amplification of d(CAG·CTG), d(CGG·CCG) or…”
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Molecular detection of micrometastatic breast cancer in histopathology-negative axillary lymph nodes correlates with traditional predictors of prognosis: an interim analysis of a prospective multi-institutional cohort study by Gillanders, William E, Mikhitarian, Kaidi, Hebert, Renee, Mauldin, Patrick D, Palesch, Yuko, Walters, Christian, Urist, Marshall M, Mann, G Bruce, Doherty, Gerard, Herrmann, Virginia M, Hill, Arnold D, Eremin, Oleg, El-Sheemy, Mohamed, Orr, Richard K, Valle, Alvaro A, Henderson, Michael A, Dewitty, Robert L, Sugg, Sonia L, Frykberg, Eric, Yeh, Karen, Bell, Richard M, Metcalf, John S, Elliott, Bruce M, Brothers, Thomas, Robison, Jay, Mitas, Michael, Cole, David J

“…We sought to establish the clinical relevance of micrometastatic disease detected by reverse transcription polymerase chain reaction (RT-PCR) in axillary lymph…”
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The expression ratio of Map7/B2M is prognostic for survival in patients with stage II colon cancer by Blum, Craig, Graham, Amanda, Yousefzadeh, Matt, Shrout, Jessica, Benjamin, Katie, Krishna, Murli, Hoda, Raza, Hoda, Rana, Cole, David J, Garrett-Mayer, Elizabeth, Reed, Carolyn, Wallace, Michael, Mitas, Michael

“…Colorectal cancer (CRC) is the second most frequent cause of cancer-related death in the United States. To determine whether certain molecular markers might be…”
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Molecular Detection of Micrometastatic Breast Cancer in Histopathology—Negative Axillary Lymph Nodes Fails to Predict Breast Cancer Recurrence: A Final Analysis of a Prospective Multi-Institutional Cohort Study by Fisher, Carla Suzanne, Cole, David J., Mitas, Michael, Garrett-Meyer, Elizabeth, Metcalf, John S., Gillanders, William E., Mikhitarian, Kaidi, Urist, Marshall M., Mann, G. Bruce, Doherty, Gerard, Herrmann, Virginia M., Hill, Arnold D., Eremin, Oleg, El-Sheemy, Mohamed, Orr, Richard K., Valle, Alvaro A., Henderson, Michael A., Dewitty, Robert L., Sugg, Sonia L., Frykberg, Eric, Yeh, Karen, Bell, Richard M., Baker, Megan K.

“…Background To address the clinical relevance of molecular detection of occult breast cancer in sentinel lymph nodes and nonsentinel axillary lymph nodes (ALN),…”
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The Trinucleotide Repeat Sequence d(CGG)15 Forms a Heat-Stable Hairpin Containing Gsyn.cntdot.Ganti Base Pairs by Mitas, Michael, Yu, Adong, Dill, Jeffrey, Haworth, Ian S

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Detection of Telomerase Expression in Mediastinal Lymph Nodes of Patients with Lung Cancer by Wallace, Michael B, Block, Mark, Hoffman, Brenda J, Hawes, Robert H, Silvestri, Gerard, Reed, Carolyn E, Mitas, Michael, Ravenel, James, Fraig, Mostafa, Miller, Scott, Jones, Edward T, Boylan, Alice

“…Mediastinal lymph nodes are the most common site of tumor spread in non-small cell lung cancer (NSCLC). We hypothesized that micrometastatic disease could be…”
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