Search Results - "MISRA, Anjan"

Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis by Phillips, Heidi S., Kharbanda, Samir, Chen, Ruihuan, Forrest, William F., Soriano, Robert H., Wu, Thomas D., Misra, Anjan, Nigro, Janice M., Colman, Howard, Soroceanu, Liliana, Williams, P. Mickey, Modrusan, Zora, Feuerstein, Burt G., Aldape, Ken

“…Previously undescribed prognostic subclasses of high-grade astrocytoma are identified and discovered to resemble stages in neurogenesis. One tumor class…”
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Advanced glycation end product (AGE) targeting antibody SIWA318H is efficacious in preclinical models for pancreatic cancer by Rossi, Gabriela R., Jensen, Ashley, Ng, Serina, Yin, Zhirong, Li, Aimin, Misra, Anjan, Von Hoff, Daniel D., Gruber, Lewis, Gruber, Misty, Han, Haiyong

“…SIWA318H is a novel monoclonal antibody that selectively targets an advanced glycation end product biomarker found in damaged/dysfunctional cells exhibiting…”
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Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma by NIGRO, Janice M, MISRA, Anjan, YUNG, W. K, FEUERSTEIN, Burt G, ALDAPE, Kenneth D, ZHANG, Li, SMIRNOV, Ivan, COLMAN, Howard, GRIFFIN, Chandi, OZBURN, Natalie, CHEN, Mingang, PAN, Edward, KOUL, Dimpy

“…Glioblastoma, the most aggressive primary brain tumor in humans, exhibits a large degree of molecular heterogeneity. Understanding the molecular pathology of a…”
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The Wnt inhibitory factor 1 (WIF1) is targeted in glioblastoma and has a tumor suppressing function potentially by induction of senescence by Lambiv, Wanyu L., Vassallo, Irene, Delorenzi, Mauro, Shay, Tal, Diserens, Annie-Claire, Misra, Anjan, Feuerstein, Burt, Murat, Anastasia, Migliavacca, Eugenia, Hamou, Marie-France, Sciuscio, Davide, Burger, Raphael, Domany, Eytan, Stupp, Roger, Hegi, Monika E.

“…Gene expression-based prediction of genomic copy number aberrations in the chromosomal region 12q13 to 12q15 that is flanked by MDM2 and CDK4 identified Wnt…”
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Angiogenesis-Independent Tumor Growth Mediated by Stem-Like Cancer Cells by Sakariassen, Per Ø., Prestegarden, Lars, Wang, Jian, Skaftnesmo, Kai-Ove, Mahesparan, Rupavathana, Molthoff, Carla, Sminia, Peter, Sundlisæter, Eirik, Misra, Anjan, Tysnes, Berit Bølge, Chekenya, Martha, Peters, Hans, Lende, Gabriel, Kalland, Karl Henning, Øyan, Anne M., Petersen, Kjell, Jonassen, Inge, van der Kogel, Albert, Feuerstein, Burt G., Terzis, A. Jorge A., Bjerkvig, Rolf, Enger, Per Øyvind

“…In this work, highly infiltrative brain tumors with a stem-like phenotype were established by xenotransplantation of human brain tumors in immunodeficient nude…”
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Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma by Soroceanu, Liliana, Kharbanda, Samir, Chen, Ruihuan, Soriano, Robert H, Aldape, Ken, Misra, Anjan, Zha, Jiping, Forrest, William F, Nigro, Janice M, Modrusan, Zora, Feuerstein, Burt G, Phillips, Heidi S

“…Amplification or overexpression of growth factor receptors is a frequent occurrence in malignant gliomas. Using both expression profiling and in situ…”
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AKT pathway genes define 5 prognostic subgroups in glioblastoma by Joy, Anna, Ramesh, Archana, Smirnov, Ivan, Reiser, Mark, Misra, Anjan, Shapiro, William R, Mills, Gordon B, Kim, Seungchan, Feuerstein, Burt G

“…Activity of GFR/PI3K/AKT pathway inhibitors in glioblastoma clinical trials has not been robust. We hypothesized variations in the pathway between tumors…”
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Functional inactivation of the KLF6 tumor suppressor gene by loss of heterozygosity and increased alternative splicing in glioblastoma by Camacho‐Vanegas, Olga, Narla, Goutham, Teixeira, Miriam S., DiFeo, Analisa, Misra, Anjan, Singh, Gobind, Chan, Andrew M., Friedman, Scott L., Feuerstein, Burt G., Martignetti, John A.

“…Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor and possesses a high incidence of 10p loss. The KLF6 (Kruppel‐like…”
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Isochromosome 17q Is a Negative Prognostic Factor in Poor-Risk Childhood Medulloblastoma Patients by PAN, Edward, PELLARIN, Malgorzata, HOLMES, Emi, SMIRNOV, Ivan, MISRA, Anjan, EBERHART, Charles G, BURGER, Peter C, BIEGEL, Jaclyn A, FEUERSTEIN, Burt G

“…Background: Medulloblastomas are the most common primary malignant childhood intracranial neoplasms. Patients are currently sorted into three risk groups based…”
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Frequent loss of heterozygosity and altered expression of the candidate tumor suppressor gene 'FAT' in human astrocytic tumors by Chosdol, Kunzang, Misra, Anjan, Puri, Sachin, Srivastava, Tapasya, Chattopadhyay, Parthaprasad, Sarkar, Chitra, Mahapatra, Ashok K, Sinha, Subrata

“…We had earlier used the comparison of RAPD (Random Amplification of Polymorphic DNA) DNA fingerprinting profiles of tumor and corresponding normal DNA to…”
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Chromosomal imbalances detected by array comparative genomic hybridization in human oligodendrogliomas and mixed oligoastrocytomas by Kitange, Gaspar, Misra, Anjan, Law, Mark, Passe, Sandra, Kollmeyer, Thomas M., Maurer, Matthew, Ballman, Karla, Feuerstein, Burt G., Jenkins, Robert B.

“…Loss of heterozygosity and fluorescence in situ hybridization (FISH) studies have shown that deletions of 1p and 19q are highly prevalent in oligodendroglioma…”
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Array Comparative Genomic Hybridization Identifies Genetic Subgroups in Grade 4 Human Astrocytoma by MISRA, Anjan, PELLARIN, Malgorzata, NIGRO, Janice, SMIRNOV, Ivan, MOORE, Dan, LAMBORN, Kathleen R, PINKEL, Daniel, ALBERTSON, Donna G, FEUERSTEIN, Burt G

“…Alterations of DNA copy number are believed to be important indicators of tumor progression in human astrocytoma. We used an array of bacterial artificial…”
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Amplifying small amounts of tumor DNA allows detection of DNA copy number aberrations with array-CGH by Lars Prestegarden, Anjan Misra, Marcus L. Ware, Ru-Fang Yeh, Rolf Bjerkvig, Burt G. Feuerstein

“…Array comparative genomic hybridization (aCGH) is a powerful tool to detect relative DNA copy number at a resolution limited only by the coverage of bacterial…”
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Clonal mutations in primary human glial tumors: evidence in support of the mutator hypothesis by Misra, Anjan, Chattopadhyay, Parthaprasad, Chosdol, Kunzang, Sarkar, Chitra, Mahapatra, Ashok K, Sinha, Subrata

“…A verifiable consequence of the mutator hypothesis is that even low grade neoplasms would accumulate a large number of mutations that do not influence the…”
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Phage Displayed Antibodies to Heat Stable Alkaline Phosphatase: Framework Region as a Determinant of Specificity by Kala, Mrinalini, Misra, Anjan, Saini, Deepti, Bajaj, Kiran, Sinha, Subrata

“…Human antibodies against specific targets of tumor cells are the most desirable molecules for possible immunotherapy. They could be developed by using the…”
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Pituicytoma: characterization of a unique neoplasm by histology, immunohistochemistry, ultrastructure, and array-based comparative genomic hybridization by Phillips, Joanna J, Misra, Anjan, Feuerstein, Burt G, Kunwar, Sandeep, Tihan, Tarik

“…The pituicytoma is a rare neoplasm whose histogenesis is debated partly because of the diversity of tissue types present in the sellar region. In this article…”
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Abstract 433: Role of AQP1 in invasion of GBM by Samuelson, Gay, Feuerstein, Burt, Misra, Anjan, Bennett, Kevin

“…Abstract There has been little improvement in glioblastoma multiforme (GBM) patient prognosis over the past 20 years despite advances in imaging, neurosurgery,…”
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Abstract 3688: Akt pathway genes classify GBM into 6 prognostic subgroups with different clinical and molecular features by Joy, Anna M., Ramesh, Archana, Smirnov, Ivan, Misra, Anjan, Shapiro, William, Phillips, Heidi, Aldape, Ken, Mills, Gordon, Kim, Seungchan, Feuerstein, Burt

“…Abstract The Akt pathway is a therapeutic target in Glioblastoma Multiforme (GBM) and an important determinant of patient outcome. However, it is not known if…”
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Integrated genomic and epigenomic analyses pinpoint biallelic gene inactivation in tumors by Costello, Joseph F, Zardo, Giuseppe, Tiirikainen, Maarit I, Hong, Chibo, Misra, Anjan, Feuerstein, Burt G, Volik, Stanislav, Collins, Colin C, Lamborn, Kathleen R, Bollen, Andrew, Pinkel, Daniel, Albertson, Donna G

“…Aberrant methylation of CpG islands and genomic deletion are two predominant mechanisms of gene inactivation in tumorigenesis, but the extent to which they…”
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Abstract 1132: PTPRD is a frequent tumor suppressor in malignant astrocytoma by Misra, Anjan, Smirnov, Ivan, Morrow, Colin, Eschbacher, Jenny, Schendel, Cheryl, Kharbanda, Samir, Phillips, Heidi, Coons, Stephen, Feuerstein, Burt G.

“…Abstract A slew of loss of heterozygosity studies for over more than a decade indicated existance of tumor suppressor/s other than p16 on 9p. With high…”
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