Search Results - "MISHIMA, Yuji"

Platelets promote tumor growth and metastasis via direct interaction between Aggrus/podoplanin and CLEC-2 by Takagi, Satoshi, Sato, Shigeo, Oh-hara, Tomoko, Takami, Miho, Koike, Sumie, Mishima, Yuji, Hatake, Kiyohiko, Fujita, Naoya

“…The platelet aggregation-inducing factor Aggrus, also known as podoplanin, is frequently upregulated in several types of tumors and enhances hematogenous…”
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Antibody-Dependent Cellular Phagocytosis by Macrophages is a Novel Mechanism of Action of Elotuzumab by Kurdi, Ahmed T, Glavey, Siobhan V, Bezman, Natalie A, Jhatakia, Amy, Guerriero, Jennifer L, Manier, Salomon, Moschetta, Michele, Mishima, Yuji, Roccaro, Aldo, Detappe, Alexandre, Liu, Chia-Jen, Sacco, Antonio, Huynh, Daisy, Tai, Yu-Tzu, Robbins, Michael D, Azzi, Jamil, Ghobrial, Irene M

“…Elotuzumab, a recently approved antibody for the treatment of multiple myeloma, has been shown to stimulate Fcγ receptor (FcγR)-mediated antibody-dependent…”
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Metabolic signature identifies novel targets for drug resistance in multiple myeloma by Maiso, Patricia, Huynh, Daisy, Moschetta, Michele, Sacco, Antonio, Aljawai, Yosra, Mishima, Yuji, Asara, John M, Roccaro, Aldo M, Kimmelman, Alec C, Ghobrial, Irene M

“…Drug resistance remains a major clinical challenge for cancer treatment. Multiple myeloma is an incurable plasma cell cancer selectively localized in the bone…”
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Efficacy of mirabegron, a β3‐adrenoreceptor agonist, in Japanese women with overactive bladder and either urgency urinary incontinence or mixed urinary incontinence: Post‐hoc analysis of pooled data from two randomized, placebo‐controlled, double‐blind studies by Takahashi, Satoru, Mishima, Yuji, Kuroishi, Kentaro, Ukai, Masashi

“…Objective To confirm if mirabegron 50 mg shows efficacy in women with overactive bladder and either urgency urinary incontinence or mixed urinary incontinence…”
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Development of antigen‐prediction algorithm for personalized neoantigen vaccine using human leukocyte antigen transgenic mouse by Charneau, Jimmy, Suzuki, Toshihiro, Shimomura, Manami, Fujinami, Norihiro, Mishima, Yuji, Hiranuka, Kazushi, Watanabe, Noriko, Yamada, Takashi, Nakamura, Norihiro, Nakatsura, Tetsuya

“…Immunotherapy is currently recognized as the fourth modality in cancer therapy. CTL can detect cancer cells via complexes involving human leukocyte antigen…”
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Engineered nanomedicine for myeloma and bone microenvironment targeting by Swami, Archana, Reagan, Michaela R., Basto, Pamela, Mishima, Yuji, Kamaly, Nazila, Glavey, Siobhan, Zhang, Sufeng, Moschetta, Michele, Seevaratnam, Dushanth, Zhang, Yong, Liu, Jinhe, Memarzadeh, Masoumeh, Wu, Jun, Manier, Salomon, Shi, Jinjun, Bertrand, Nicolas, Lu, Zhi Ning, Nagano, Kenichi, Baron, Roland, Sacco, Antonio, Roccaro, Aldo M., Farokhzad, Omid C., Ghobrial, Irene M.

“…Bone is a favorable microenvironment for tumor growth and a frequent destination for metastatic cancer cells. Targeting cancers within the bone marrow remains…”
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C1013G/CXCR4 acts as a driver mutation of tumor progression and modulator of drug resistance in lymphoplasmacytic lymphoma by Roccaro, Aldo M., Sacco, Antonio, Jimenez, Cristina, Maiso, Patricia, Moschetta, Michele, Mishima, Yuji, Aljawai, Yosra, Sahin, Ilyas, Kuhne, Michelle, Cardarelli, Pina, Cohen, Lewis, San Miguel, Jesus F., Garcia-Sanz, Ramon, Ghobrial, Irene M.

“…The C-X-C chemokine receptor type 4 (CXCR4) plays a crucial role in modulating cell trafficking in hematopoietic stem cells and clonal B cells. We screened 418…”
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Blocking IFNAR1 inhibits multiple myeloma-driven Treg expansion and immunosuppression by Kawano, Yawara, Zavidij, Oksana, Park, Jihye, Moschetta, Michele, Kokubun, Katsutoshi, Mouhieddine, Tarek H, Manier, Salomon, Mishima, Yuji, Murakami, Naoka, Bustoros, Mark, Pistofidis, Romanos Sklavenitis, Reidy, Mairead, Shen, Yu J, Rahmat, Mahshid, Lukyanchykov, Pavlo, Karreci, Esilida Sula, Tsukamoto, Shokichi, Shi, Jiantao, Takagi, Satoshi, Huynh, Daisy, Sacco, Antonio, Tai, Yu-Tzu, Chesi, Marta, Bergsagel, P Leif, Roccaro, Aldo M, Azzi, Jamil, Ghobrial, Irene M

“…Despite significant advances in the treatment of multiple myeloma (MM), most patients succumb to disease progression. One of the major immunosuppressive…”
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The clonal evolution during long-term clinical course of multiple myeloma by Mishima, Yuko, Mishima, Yuji, Shirouchi, Yuko, Nishimura, Noriko, Yokoyama, Masahiro, Okabe, Takashi, Inoue, Norihito, Uryu, Hideki, Fukuta, Takanori, Hatake, Kiyohiko, Terui, Yasuhito

“…Somatic gene mutations related to acceleration disease and clonal evolution in multiple myeloma strongly influence severe clinical outcomes. In this study, we…”
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Platelets Enhance Multiple Myeloma Progression via IL-1β Upregulation by Takagi, Satoshi, Tsukamoto, Shokichi, Park, Jihye, Johnson, Kelly E, Kawano, Yawara, Moschetta, Michele, Liu, Chia-Jen, Mishima, Yuji, Kokubun, Katsutoshi, Manier, Salomon, Salem, Karma Z, Huynh, Daisy, Sacco, Antonio, Forward, Jodi, Roccaro, Aldo M, Battinelli, Elisabeth M, Ghobrial, Irene M

“…Tumor cell-platelet interactions contribute to tumor progression and metastasis in solid tumors. However, the role of platelets in hematological malignancies…”
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Circulating tumor cells as a surrogate marker for determining response to chemotherapy in patients with advanced gastric cancer by Matsusaka, Satoshi, Chìn, Keisho, Ogura, Mariko, Suenaga, Mitsukuni, Shinozaki, Eiji, Mishima, Yuji, Terui, Yasuhito, Mizunuma, Nobuyuki, Hatake, Kiyohiko

“…The purpose of this study was to quantify circulating tumor cells (CTCs) in advanced gastric cancer (AGC) patients, and to demonstrate the role of CTCs in…”
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Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model by Reagan, Michaela R., Mishima, Yuji, Glavey, Siobhan V., Zhang, Yong, Manier, Salomon, Lu, Zhi Ning, Memarzadeh, Masoumeh, Zhang, Yu, Sacco, Antonio, Aljawai, Yosra, Shi, Jiantao, Tai, Yu-Tzu, Ready, John E., Kaplan, David L., Roccaro, Aldo M., Ghobrial, Irene M.

“…Clonal proliferation of plasma cells within the bone marrow (BM) affects local cells, such as mesenchymal stromal cells (MSCs), leading to osteolysis and…”
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CXCR4 Regulates Extra-Medullary Myeloma through Epithelial-Mesenchymal-Transition-like Transcriptional Activation by Roccaro, Aldo M., Mishima, Yuji, Sacco, Antonio, Moschetta, Michele, Tai, Yu-Tzu, Shi, Jiantao, Zhang, Yong, Reagan, Michaela R., Huynh, Daisy, Kawano, Yawara, Sahin, Ilyas, Chiarini, Marco, Manier, Salomon, Cea, Michele, Aljawai, Yosra, Glavey, Siobhan, Morgan, Elizabeth, Pan, Chin, Michor, Franziska, Cardarelli, Pina, Kuhne, Michelle, Ghobrial, Irene M.

“…Extra-medullary disease (EMD) in multiple myeloma (MM) is associated with poor prognosis and resistance to chemotherapy. However, molecular alterations that…”
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The Mutational Landscape of Circulating Tumor Cells in Multiple Myeloma by Mishima, Yuji, Paiva, Bruno, Shi, Jiantao, Park, Jihye, Manier, Salomon, Takagi, Satoshi, Massoud, Mira, Perilla-Glen, Adriana, Aljawai, Yosra, Huynh, Daisy, Roccaro, Aldo M., Sacco, Antonio, Capelletti, Marzia, Detappe, Alexandre, Alignani, Diego, Anderson, Kenneth C., Munshi, Nikhil C., Prosper, Felipe, Lohr, Jens G., Ha, Gavin, Freeman, Samuel S., Van Allen, Eliezer M., Adalsteinsson, Viktor A., Michor, Franziska, San Miguel, Jesus F., Ghobrial, Irene M.

“…The development of sensitive and non-invasive “liquid biopsies” presents new opportunities for longitudinal monitoring of tumor dissemination and clonal…”
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The sialyltransferase ST3GAL6 influences homing and survival in multiple myeloma by Glavey, Siobhan V., Manier, Salomon, Natoni, Alessandro, Sacco, Antonio, Moschetta, Michele, Reagan, Michaela R., Murillo, Laura S., Sahin, Ilyas, Wu, Ping, Mishima, Yuji, Zhang, Yu, Zhang, Wenjing, Zhang, Yong, Morgan, Gareth, Joshi, Lokesh, Roccaro, Aldo M., Ghobrial, Irene M., O'Dwyer, Michael E.

“…Glycosylation is a stepwise procedure of covalent attachment of oligosaccharide chains to proteins or lipids, and alterations in this process, especially…”
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SDF-1 inhibition targets the bone marrow niche for cancer therapy by Roccaro, Aldo M, Sacco, Antonio, Purschke, Werner G, Moschetta, Michele, Buchner, Klaus, Maasch, Christian, Zboralski, Dirk, Zöllner, Stefan, Vonhoff, Stefan, Mishima, Yuji, Maiso, Patricia, Reagan, Michaela R, Lonardi, Silvia, Ungari, Marco, Facchetti, Fabio, Eulberg, Dirk, Kruschinski, Anna, Vater, Axel, Rossi, Giuseppe, Klussmann, Sven, Ghobrial, Irene M

“…Bone marrow (BM) metastasis remains one of the main causes of death associated with solid tumors as well as multiple myeloma (MM). Targeting the BM niche to…”
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Thermal Decomposition Behavior of a Chelating Resin Immobilizing Carboxymethylated Polyethyleneimine: Possibility of Estimation of Carboxymethylation Rate by KAGAYA, Shigehiro, MISHIMA, Yuji, OBATA, Issei, GEMMEI-IDE, Makoto, INOUE, Yoshinori, TSUGOSHI, Takahisa

“…Chelating resins immobilizing carboxymethylated polyethyleneimine (CM-PEI) with different carboxymethylation rates were prepared. The thermal decomposition…”
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Circulating tumor cells as a surrogate marker for determining response to chemotherapy in Japanese patients with metastatic colorectal cancer by Matsusaka, Satoshi, Suenaga, Mitsukuni, Mishima, Yuji, Kuniyoshi, Ryoko, Takagi, Koichi, Terui, Yasuhito, Mizunuma, Nobuyuki, Hatake, Kiyohiko

“…The purpose of this study was to investigate the potential of circulating tumor cells (CTC) as a surrogate marker of the clinical outcome in metastatic…”
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Pyk2 promotes tumor progression in multiple myeloma by Zhang, Yu, Moschetta, Michele, Huynh, Daisy, Tai, Yu-Tzu, Zhang, Yong, Zhang, Wenjing, Mishima, Yuji, Ring, Jennifer E., Tam, Winnie F., Xu, Qunli, Maiso, Patricia, Reagan, Michaela, Sahin, Ilyas, Sacco, Antonio, Manier, Salomon, Aljawai, Yosra, Glavey, Siobhan, Munshi, Nikhil C., Anderson, Kenneth C., Pachter, Jonathan, Roccaro, Aldo M., Ghobrial, Irene M.

“…Proline-rich tyrosine kinase 2 (Pyk2) is a member of the focal adhesion kinase family that has been recently linked to tumor development. However, its role in…”
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MEM Charge Density Study of Olivine LiMPO4 and MPO4 (M = Mn, Fe) as Cathode Materials for Lithium-Ion Batteries by Mishima, Yuji, Hojo, Takuma, Nishio, Takahisa, Sadamura, Hideaki, Oyama, Noboru, Moriyoshi, Chikako, Kuroiwa, Yoshihiro

“…We have investigated the electron-density distributions in LiMPO4 and MPO4 (M = Mn, Fe) by analyzing high-energy synchrotron-radiation powder-diffraction data…”
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