Search Results - "MISASI, ROBERTA"
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Evidence for the involvement of lipid rafts localized at the ER-mitochondria associated membranes in autophagosome formation
Published in Autophagy (02-06-2016)“…Mitochondria-associated membranes (MAMs) are subdomains of the endoplasmic reticulum (ER) that interact with mitochondria. This membrane scrambling between ER…”
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Different domains of β2-glycoprotein I play a role in autoimmune pathogenesis
Published in Cellular & molecular immunology (01-11-2020)Get full text
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Protein Aggregation Landscape in Neurodegenerative Diseases: Clinical Relevance and Future Applications
Published in International journal of molecular sciences (02-06-2021)“…Intrinsic disorder is a natural feature of polypeptide chains, resulting in the lack of a defined three-dimensional structure. Conformational changes in…”
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Molecular Mechanisms of "Antiphospholipid Antibodies" and Their Paradoxical Role in the Pathogenesis of "Seronegative APS"
Published in International journal of molecular sciences (09-11-2020)“…Antiphospholipid Syndrome (APS) is an autoimmune disease characterized by arterial and/or venous thrombosis and/or pregnancy morbidity, associated with…”
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Evidence for the involvement of GD3 ganglioside in autophagosome formation and maturation
Published in Autophagy (01-05-2014)“…Sphingolipids are structural lipid components of cell membranes, including membrane of organelles, such as mitochondria or endoplasmic reticulum, playing a…”
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The Role of Autophagy as a Trigger of Post-Translational Modifications of Proteins and Extracellular Vesicles in the Pathogenesis of Rheumatoid Arthritis
Published in International journal of molecular sciences (01-08-2023)“…Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease, characterized by persistent joint inflammation, leading to cartilage and bone destruction…”
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Targeting Lipid Rafts as a Strategy Against Coronavirus
Published in Frontiers in cell and developmental biology (04-02-2021)“…Lipid rafts are functional membrane microdomains containing sphingolipids, including gangliosides, and cholesterol. These regions are characterized by highly…”
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Role of mitochondrial raft-like microdomains in the regulation of cell apoptosis
Published in Apoptosis (London) (01-05-2015)“…Lipid rafts are envisaged as lateral assemblies of specific lipids and proteins that dissociate and associate rapidly and form functional clusters in cell…”
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Anti-Inflammatory Activity of a CB2 Selective Cannabinoid Receptor Agonist: Signaling and Cytokines Release in Blood Mononuclear Cells
Published in Molecules (Basel, Switzerland) (23-12-2021)“…The endocannabinoid system (ECS) exerts immunosuppressive effects, which are mostly mediated by cannabinoid receptor 2 (CBR2), whose expression on leukocytes…”
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Autophagy Promotes Enrichment of Raft Components within Extracellular Vesicles Secreted by Human 2FTGH Cells
Published in International journal of molecular sciences (01-06-2024)“…Autophagy plays a key role in removing protein aggregates and damaged organelles. In addition to its conventional degradative functions, autophagy machinery…”
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Anti-Proliferative Properties and Proapoptotic Function of New CB2 Selective Cannabinoid Receptor Agonist in Jurkat Leukemia Cells
Published in International journal of molecular sciences (04-07-2018)“…Several studies demonstrated that cannabinoids reduce tumor growth, inhibit angiogenesis, and decrease cancer cell migration. As these molecules are well…”
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Role of lipid rafts in neuronal differentiation of dental pulp-derived stem cells
Published in Experimental cell research (10-12-2015)“…Human dental pulp-derived stem cells (hDPSCs) are characterized by a typical fibroblast-like morphology. They express specific markers for mesenchymal stem…”
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Editorial for Special Issue: Neuroglobin from Brain Protection to Cancer Progression
Published in Cells (Basel, Switzerland) (13-07-2022)“…Since its discovery in 2000 [...]…”
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Cardiolipin-enriched raft-like microdomains are essential activating platforms for apoptotic signals on mitochondria
Published in FEBS letters (06-08-2009)“…Cardiolipin (CL) has recently been shown to provide an anchor and an essential activating platform for caspase-8 on mitochondria. We hypothesize that these…”
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Relationship Between Gender Differences and Clinical Outcome in Patients With the Antiphospholipid Syndrome
Published in Frontiers in immunology (04-07-2022)“…Antiphospholipid syndrome (APS), characterized by artherial and/or venous thrombosis, pregnancy morbidity and “antiphospholipid” antibodies (aPLs), is more…”
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Signal transduction pathway involved in platelet activation in immune thrombotic thrombocytopenia after COVID-19 vaccination
Published in Haematologica (Roma) (01-01-2022)Get full text
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Proteome data of neuroblastoma cells overexpressing Neuroglobin
Published in Data in brief (01-04-2022)“…In this article, we present data on the proteome of human neuroblastoma cells stably overexpressing Neuroglobin (NGB). The neuroprotective role of NGB is…”
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The Role of Cardiolipin as a Scaffold Mitochondrial Phospholipid in Autophagosome Formation: In Vitro Evidence
Published in Biomolecules (Basel, Switzerland) (05-02-2021)“…Cardiolipin (CL) is a hallmark phospholipid localized within the inner mitochondrial membrane. Upon several mitochondrial stress conditions, CL is translocated…”
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Antiphospholipid antibodies in patients with stroke during COVID-19: A role in the signaling pathway leading to platelet activation
Published in Frontiers in immunology (02-03-2023)“…Several viral and bacterial infections, including COVID-19, may lead to both thrombotic and hemorrhagic complications. Previously, it has been demonstrated an…”
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Role of ERLINs in the Control of Cell Fate through Lipid Rafts
Published in Cells (Basel, Switzerland) (13-09-2021)“…ER lipid raft-associated protein 1 (ERLIN1) and 2 (ERLIN2) are 40 kDa transmembrane glycoproteins belonging to the family of prohibitins, containing a PHB…”
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