Search Results - "MIRSKY, Israel"

Assessment of systolic and diastolic ventricular properties via pressure-volume analysis: a guide for clinical, translational, and basic researchers by Burkhoff, Daniel, Mirsky, Israel, Suga, Hiroyuki

“…Assessment of left ventricular systolic and diastolic pump properties is fundamental to advancing the understanding of cardiovascular pathophysiology and…”
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Effects of cardiac denervation on development of heart failure and catecholamine desensitization by SATO, N, VATNER, S. F, VATNER, D. E, SHEN, Y.-T, KUDEJ, R. K, GHALEH-MARZBAN, B, UECHI, M, ASAI, K, MIRSKY, I, PATRICK, T. A, SHANNON, R. P

“…Two signatures of heart failure are activation of the sympathetic nervous system and catecholamine desensitization. However, whether or not the elimination of…”
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Letter regarding article by Baicu et al, "Left ventricular systolic performance, function, and contractility in patients with diastolic heart failure" by Mirsky, Israel

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A New Approach to Assessing Regional and Global Myocardial Contractility by DOMANSKI, MICHAEL J., FOLLMANN, DEAN, MIRSKY, ISRAEL

“…A number of studies that assessed myocardial contractility by noninvasive means have been conducted in the past. However, many of these studies are limited…”
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Assessment of Passive Elastic Stiffness for Isolated Heart Muscle and the Intact Heart by MIRSKY, ISRAEL, PARMLEY, WILLIAM W

“…A sensitive method was developed for detecting stiffness changes in the left ventricle. Stress-strain relationships (σ— ) were obtained in the form dσ/d = kσ +…”
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Noninvasive Assessment of Regional and Global Myocardial Contractility in Normal Control Subjects and in Patients with Dilated Cardiomyopathies by DOMANSKI, MICHAEL J., FOLLMAN, DEAN, KRAVITZ, MARSHA, MIRSKY, ISRAEL

“…The aim of the present study was to develop a new noninvasive approach for the assessment of regional and global myocardial contractility without the need for…”
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Assessment of left ventricular stiffness in primary myocardial disease and coronary artery disease by Mirsky, I, Cohn, P F, Levine, J A, Gorlin, R, Herman, M V, Kreulen, T H, Sonnenblick, E H

“…Stress-strain relations (σ-ε) were obtained in the form dσ/dε = kσ + c, where k is a stiffness constant. Utilizing the pressure-volume relation dP/dV = αP, the…”
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Clinical assessment of diastolic function by Mirsky, I, Pasipoularides, A

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Hemodynamic mechanisms responsible for reduced subendocardial coronary reserve in dogs with severe left ventricular hypertrophy by HITTINGER, L, MIRSKY, I, YOU-TANG SHEN, PATRICK, T. A, BISHOP, S. P, VATNER, S. F

“…Reduced subendocardial coronary reserve is a hallmark of left ventricular hypertrophy (LVH). The goal of this study was to determine whether hemodynamic, as…”
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Maturation-dependent differences in regulation of sarcoplasmic reticulum Ca(2+) ATPase in sheep myocardium in response to pressure overload: a possible mechanism for maturation-dependent systolic and diastolic dysfunction by Aoyagi, T, Fujii, A M, Flanagan, M F, Arnold, L, Mirsky, I, Izumo, S

“…We have previously demonstrated that pressure-overload hypertrophy in adult sheep is associated with myocardial dysfunction whereas that in young lambs is…”
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Comparison of echocardiography and radionuclide angiography as predictors of mortality in patients with left ventricular dysfunction (studies of left ventricular dysfunction) by Rashid, Haroon, Exner, Derek V, Mirsky, Israel, Cooper, Howard A, Waclawiw, Myron A, Domanski, Michael J

“…Left ventricular (LV) systolic dysfunction, as indicated by a reduced LV ejection fraction (EF) is a potent predictor of cardiovascular mortality. Radionuclide…”
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Myocardial Contractility and Contraction Duration Are Unrelated in the Left Ventricle with Moderate Pressure-Overload Hypertrophy by AOYAGI, Teruhiko, MOMOMURA, Shin-ichi, MATSUI, Hiroshi, SERIZAWA, Takashi, IIZUKA, Masahiko, HIRATA, Yasunobu, SUGIMOTO, Tsuneaki, MIRSKY, Israel

“…Both myocardial contractility and contraction duration were assessed load-independently in isolated hypertrophic and control rat hearts. Hemodynamic parameters…”
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Maturation-dependent differences in regulation of sarcoplasmic reticulum Ca2+ atpase in sheep myocardium in response to pressure overload : A possible mechanism for maturation-dependent systolic and diastolic dysfunction by AOYAGI, Teruhiko, FUJII, Alan M, FLANAGAN, Michael F, ARNOLD, Lucy, MIRSKY, Israel, IZUMO, Seigo

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Application of the Systolic Stiffness Concept to Assess Myocardial Function in Developing Hypertension by AOYAGI, Teruhiko, FUJII, Alan M., GELPI, Ricardo J., HITTINGER, Luc, CROCKER, Valerie M., MIRSKY, Israel

“…The concept of end-systolic myocardial stiffness permits the quantification of preload effects on fiber shortening and changes in the slope (max Eav) of the…”
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Effects of beta-adrenergic stimulation with dobutamine on isovolumic relaxation in the normal and failing human left ventricle by Parker, J D, Landzberg, J S, Bittl, J A, Mirsky, I, Colucci, W S

“…We tested the hypothesis that beta-adrenergic receptor-stimulated acceleration of left ventricular (LV) isovolumic relaxation (i.e., positive lusitropic…”
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An appraisal of ventricular and myocardial function variables based on the elastance concept by Mirsky, Israel

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Preload dependence of fiber shortening rate in conscious dogs with left verntricular hypertrophy by Mirsky, Israel, Aoyagi, Teruhiko, Crocker, Valerie Marion, Fujii, Alan M.

“…Employing the new concept of systolic myocardial stiffness, this study addresses the questions of linearity of the end-systolic stress-strain relations in left…”
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Transition from compensated hypertrophy to intrinsic myocardial dysfunction during development of left ventricular pressure-overload hypertrophy in conscious sheep. Systolic dysfunction precedes diastolic dysfunction by Aoyagi, T, Fujii, A M, Flanagan, M F, Arnold, L W, Brathwaite, K W, Colan, S D, Mirsky, I

“…Patients with aortic stenosis have a period of compensated left ventricular hypertrophy but may eventually develop congestive heart failure. Previous…”
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Regression of Left Ventricular Hypertrophy and Prevention of Left Ventricular Dysfunction by Captopril in the Spontaneously Hypertensive Rat by Pfeffer, Janice M., Pfeffer, Marc A., Mirsky, Israel, Braunwald, Eugene

“…To determine whether chronic antihypertensive therapy prevents the progression of cardiac hypertrophy and the deterioration in cardiac performance observed in…”
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V max as an Index of Contractile State in Man: Reply to Dr. Katz by MIRSKY, ISRAEL

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