Search Results - "MIRSKY, I"

Assessment of diastolic function: suggested methods and future considerations by Mirsky, I

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Exhaustion of Frank-Starling mechanism in conscious dogs with heart failure by Komamura, K, Shannon, R P, Ihara, T, Shen, Y T, Mirsky, I, Bishop, S P, Vatner, S F

“…The goal of this study was to elucidate the ability of the left ventricle to accommodate an increase in preload (Frank-Starling mechanism) in the presence of…”
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Clinical assessment of diastolic function by Mirsky, I, Pasipoularides, A

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The development of the entire end-systolic pressure-volume and ejection fraction-afterload relations: a new concept of systolic myocardial stiffness by MIRSKY, I, TAJIMI, T, PETERSON, K. L

“…In this study we introduce a new concept of systolic myocardial stiffness that extends the Suga-Sagawa maximum ventricular elastance concept to the myocardium…”
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Regression of Left Ventricular Hypertrophy and Prevention of Left Ventricular Dysfunction by Captopril in the Spontaneously Hypertensive Rat by Pfeffer, Janice M., Pfeffer, Marc A., Mirsky, Israel, Braunwald, Eugene

“…To determine whether chronic antihypertensive therapy prevents the progression of cardiac hypertrophy and the deterioration in cardiac performance observed in…”
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Transition from compensated hypertrophy to intrinsic myocardial dysfunction during development of left ventricular pressure-overload hypertrophy in conscious sheep. Systolic dysfunction precedes diastolic dysfunction by Aoyagi, T, Fujii, A M, Flanagan, M F, Arnold, L W, Brathwaite, K W, Colan, S D, Mirsky, I

“…Patients with aortic stenosis have a period of compensated left ventricular hypertrophy but may eventually develop congestive heart failure. Previous…”
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Effects of left ventricular volume overload produced by mitral regurgitation on diastolic function by Zile, M R, Tomita, M, Nakano, K, Mirsky, I, Usher, B, Lindroth, J, Carabello, B A

“…We hypothesized that the left ventricle's ability to compensate for the volume overload produced by mitral regurgitation (MR) depends, at least in part, on…”
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Left ventricular systolic dysfunction precedes diastolic dysfunction during myocardial ischemia in conscious dogs by Ihara, T, Komamura, K, Shen, Y T, Patrick, T A, Mirsky, I, Shannon, R P, Vatner, S F

“…We studied the initial effects of regional and global left ventricular (LV) ischemia induced by left circumflex and left main coronary artery occlusion (CAO),…”
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Assessment of passive elastic stiffness of cardiac muscle: mathematical concepts, physiologic and clinical considerations, directions of future research by Mirsky, I

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Myocardial relaxation and passive diastolic properties in man by PASAPOULARIDES, A, MIRSKY, I, HESS, O. M, GRIMM, J, KRAYENBUEHL, H. P

“…We have developed a model for assessing the influence of the decaying contractile systolic tension on diastolic wall dynamics and the passive properties of…”
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The Contractile State as the Major Determinant in the Evolution of Left Ventricular Dysfunction in the Spontaneously Hypertensive Rat by Mirksy, Israel, Pfeffer, Janice M, Pfeffer, Marc A, Braunwald, Eugene

“…Female spontaneously hypertensive and normotensive rats were studied at 6, 12, 18, and 24 months of age to determine which characteristics of myocardial…”
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Left Ventricular Stresses in the Intact Human Heart by Mirsky, I.

“…A set of stress differential equations of equilibrium is presented for a thick prolate spheroid which is the assumed shape for the left ventricle. An analysis…”
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Ventricular and Arterial Wall Stresses Based on Large Deformation Analyses by Mirsky, I.

“…Assuming a spherical geometry for the left ventricle and a cylindrical geometry for arteries, wall stresses and elastic stiffnesses are evaluated on the basis…”
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Myocardial function in immature and mature sheep with pressure-overload hypertrophy by Aoyagi, T, Mirsky, I, Flanagan, M F, Currier, J J, Colan, S D, Fujii, A M

“…The effect of pressure-overload left ventricular hypertrophy (LVH) on myocardial function is controversial. A major factor in the controversy may be the age at…”
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Different effects of two types of ischemia on myocardial systolic and diastolic function by Paulus, W J, Grossman, W, Serizawa, T, Bourdillon, P D, Pasipoularides, A, Mirsky, I

“…Acute increases in left ventricular (LV) diastolic pressure relative to volume occur during angina in humans and after pacing tachycardia in dogs with coronary…”
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Increased regional myocardial stiffness of the left ventricle during pacing-induced angina in man by Bourdillon, P D, Lorell, B H, Mirsky, I, Paulus, W J, Wynne, J, Grossman, W

“…The left ventricular diastolic pressure-volume relationship shifts upward during angina, but why this happens is not known. To assess regional myocardial…”
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Contractile state is the major determinant of functional outcome in patients with left ventricular dysfunction treated with enalapril by Mirsky, I, Aoyagi, T, Ihara, T, van Eyll, C, Rousseau, M F, Pouleur, H

“…Large-scale drug trials have focused primarily on mortality and morbidity and less on the functional state of the myocardium. A model was developed to assess…”
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Correction for preload in assessment of myocardial contractility in aortic and mitral valve disease: application of the concept of systolic myocardial stiffness by MIRSKY, I, CORIN, W. J, MURAKAMI, T, GRIMM, J, HESS, O. M, KRAYENBUEHL, H. P

“…With single-beat analysis, the new concept of systolic myocardial stiffness is applied to provide a new approach for the assessment of myocardial contractility…”
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The Effects of Geometry, Elasticity, and External Pressures on the Diastolic Pressure-Volume and Stiffness-Stress Relations: How Important is the Pericardium? by MIRSKY, ISRAEL, RANKIN, J SCOTT

“…The concept of an incremental elastic modulus is applied in the quantification of passive elastic stiffness-stress relations of intact heart muscle, and a…”
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Letter: Passive elasticity of the human left ventricle by Mirsky, I

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