Search Results - "MIROWSKI, Marek"

Prognostic Significance of HMGA1 Expression in Lung Cancer Based on Bioinformatics Analysis by Saed, Lias, Jeleń, Agnieszka, Mirowski, Marek, Sałagacka-Kubiak, Aleksandra

“…High-mobility group protein 1 (HMGA1) participates in the processes of DNA transcription, replication, recombination, and repair. The HMGA1 gene is expressed…”
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Anticancer Properties of 3-Dietoxyphosphorylfuroquinoline-4,9-dione by Drogosz-Stachowicz, Joanna, Gach-Janczak, Katarzyna, Mirowski, Marek, Pietrzak, Jacek, Janecki, Tomasz, Janecka, Anna

“…Herein, the antitumor activity of a novel synthetic analog with 5,8-quinolinedione scaffold, diethyl (2-(2-chlorophenyl)-4,9-dioxo-4,9-dihydrofuro [3,2-…”
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The impact of ABCB1 gene polymorphism and its expression on non-small-cell lung cancer development, progression and therapy – preliminary report by Zawadzka, Izabela, Jeleń, Agnieszka, Pietrzak, Jacek, Żebrowska-Nawrocka, Marta, Michalska, Katarzyna, Szmajda-Krygier, Dagmara, Mirowski, Marek, Łochowski, Mariusz, Kozak, Józef, Balcerczak, Ewa

“…The ABCB1 gene belongs to ATP binding cassette (ABC) transporter genes that has been previously implicated in cancer progression and drug response. This study…”
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Natural or Synthetic Emollients? Physicochemical Properties of Body Oils in Relation to Selected Parameters of Epidermal Barrier Function by Ogorzałek, Marta, Klimaszewska, Emilia, Mirowski, Marek, Kulawik-Pióro, Agnieszka, Tomasiuk, Ryszard

“…Emollients are valued ingredients of many cosmetic products and medical devices used to support the treatment and prevention of many skin diseases. Despite the…”
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Changes in the expression of membrane type-matrix metalloproteinases genes (MMP14, MMP15, MMP16, MMP24) during treatment and their potential impact on the survival of patients with non-small cell lung cancer (NSCLC) by Pietrzak, Jacek, Szmajda-Krygier, Dagmara, Wosiak, Agnieszka, Świechowski, Rafał, Michalska, Katarzyna, Mirowski, Marek, Żebrowska-Nawrocka, Marta, Łochowski, Mariusz, Balcerczak, Ewa

“…The analysis concerned the comparison of the expression of membrane type matrix metalloproteinases genes in the blood and tissue of NSCLC patients during the…”
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Synthesis of 2,2,6-Trisubstituted 5-Methylidene-tetrahydropyran-4-ones with Anticancer Activity by Bartosik, Tomasz, Kędzia, Jacek, Drogosz-Stachowicz, Joanna, Janecka, Anna, Krajewska, Urszula, Mirowski, Marek, Janecki, Tomasz

“…In our continuous search for new, relatively simple 2-alkylidene-1-oxoheterocycles as promising anticancer drug candidates, herein we report an efficient…”
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New Uracil Analogs with Exocyclic Methylidene Group as Potential Anticancer Agents by Długosz-Pokorska, Angelika, Drogosz, Joanna, Pięta, Marlena, Janecki, Tomasz, Krajewska, Urszula, Mirowski, Marek, Janecka, Anna

“…Hybrid molecules combining uracil skeleton with methylidene exo-cyclic group were designed in the search for novel anticancer drug candidates. Two series of…”
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Association of ABCB1 T-129C polymorphism and multiple myeloma risk in Polish population by Niebudek, Katarzyna, Balcerczak, Ewa, Mirowski, Marek, Żebrowska, Marta

“…The possible interaction between gene polymorphism and cancer risk development is a very interesting issue. The genetic variants of the ATP-binding cassette…”
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ABCB1/MDR1 gene polymorphisms as a prognostic factor in colorectal cancer by Balcerczak, Ewa, Panczyk, Mariusz, Piaskowski, Sylwester, Pasz-Walczak, Grażyna, Sałagacka, Aleksandra, Mirowski, Marek

“…Objective To analyse the single-nucleotide polymorphisms (SNPs): ABCB1 1236C>T, ABCB1 2677G>T/A, ABCB1 3435C>T and haplotypes in the ABCB1/MDR1 gene, which…”
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Functional C3435T polymorphism of MDR1 gene: an impact on genetic susceptibility and clinical outcome of childhood acute lymphoblastic leukemia by Jamroziak, Krzysztof, Młynarski, Wojciech, Balcerczak, Ewa, Mistygacz, Magda, Treliǹska, Joanna, Mirowski, Marek, Bodalski, Jerzy, Robak, Tadeusz

“…: The significance of genetic background in childhood acute lymphoblastic leukemia (ALL) is not well understood. Polymorphisms of genes encoding for…”
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ABCB1 gene polymorphisms and haplotype analysis in colorectal cancer by Panczyk, Mariusz, Balcerczak, Ewa, Piaskowski, Sylwester, Jamroziak, Krzysztof, Pasz-Walczak, Grażyna, Mirowski, Marek

“…Purpose The aim of this study was to determine the significance of three most common single-nucleotide polymorphisms (SNPs) of ABCB1 gene in the development of…”
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Estimation of CYP3A41B single nucleotide polymorphism in patients with recurrent Major Depressive Disorder by Świechowski, Rafał, Jeleń, Agnieszka, Mirowski, Marek, Talarowska, Monika, Gałecki, Piotr, Pietrzak, Jacek, Wodziński, Damian, Balcerczak, Ewa

“…Background Major depression is the most common mental illness in the world. Failures in treatment may occur due to the presence of a subtype of depression…”
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Investigation of -308G>A and -1031T>C polymorphisms in the TNFA promoter region in Polish peptic ulcer patients by Sałagacka, Aleksandra, Żebrowska, Marta, Jeleń, Agnieszka, Mirowski, Marek, Balcerczak, Ewa

“…Tumor necrosis factor α (TNF-α) encoded by TNFA is a key mediator in inflammation, a precursor condition for peptic ulceration. Promoter polymorphisms of TNFA…”
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CD38 Gene Polymorphisms Contribute to Genetic Susceptibility to B-Cell Chronic Lymphocytic Leukemia: Evidence from Two Case-Control Studies in Polish Caucasians by JAMROZIAK, Krzysztof, SZEMRAJ, Zofia, KOSTYRA, Aleksandra, CALBECKA, Malgorzata, WAWRZYNIAK, Ewa, MIROWSKI, Marek, KORDEK, Radzislaw, ROBAK, Tadeusz, GRZYBOWSKA-IZYDORCZYK, Olga, SZEMRAJ, Janusz, BIENIASZ, Magdalena, CEBULA, Barbara, GIANNOPULOS, Krzysztof, BALCERCZAK, Ewa, JESIONEK-KUPNICKA, Dorota, KOWAL, Malgorzata

“…Given the recent findings on the importance of CD38 signaling in the pathogenesis of B-cell chronic lymphocytic leukemia (B-CLL), we hypothesized that single…”
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Polymorphisms and haplotypes in the multidrug resistance 1 gene ( MDR1 / ABCB1 ) and risk of multiple myeloma by Jamroziak, Krzysztof, Balcerczak, Ewa, Calka, Karolina, Piaskowski, Sylwester, Urbanska-Rys, Halina, Salagacka, Aleksandra, Mirowski, Marek, Robak, Tadeusz

“…Abstract MDR1 ( ABCB1 ) gene encodes for P-glycoprotein (P-gp, MDR1, ABCB1), an ATP-binding cassette superfamily member involved in the transport of…”
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Apoptotic gene expression under influence of fludarabine and cladribine in chronic lymphocytic leukemia-microarray study by Ida, Franiak-Pietryga, Aleksandra, Sałagacka, Henryk, Maciejewski, Jerzy, Z. Błoński, Maciej, Borowiec, Marek, Mirowski, Tadeusz, Robak, Anna, Korycka-Wołowiec

“…Background:A deep insight into gene expression profiling (GEP) is a key to understanding the background of disease. It can lead to identification of diagnostic…”
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Structure-activity relationship, conformation and pharmacology studies of morphiceptin analogues--selective mu-opioid receptor ligands by Janecka, Anna, Fichna, Jakub, Mirowski, Marek, Janecki, Tomasz

“…Morphiceptin (Tyr-Pro-Phe-Pro-NH(2)) is one of the most selective agonists for the mu-opioid receptor. In this review structure-activity relationships of…”
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Historical Perspective and Current Trends in Anticancer Drug Development by Gach-Janczak, Katarzyna, Drogosz-Stachowicz, Joanna, Janecka, Anna, Wtorek, Karol, Mirowski, Marek

“…Cancer is considered one of the leading causes of death in the 21st century. The intensive search for new anticancer drugs has been actively pursued by…”
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Anticancer properties of new synthetic hybrid molecules combining naphtho[2,3-b]furan-4,9-dione or benzo[f]indole-4,9-dione motif with phosphonate subunit by Gach, Katarzyna, Modranka, Jakub, Szymański, Jacek, Pomorska, Dorota, Krajewska, Urszula, Mirowski, Marek, Janecki, Tomasz, Janecka, Anna

“…In this paper we report an efficient and general synthesis of substituted 3-diethoxyphosphorylnaphtho [2,3-b]furan-4,9-diones and 3-diethoxyphosphorylbenzo…”
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The cytotoxic effect of Ru(II) complexes with 5-(2-hydroxyphenyl)-3-methyl-1-(2-pyridyl)-1H-pyrazole-4-carboxylic acid methyl ester: Synthesis, X-ray structure and DNA damage potential by Skoczyńska, Anna, Pasternak, Beata, Małecka, Magdalena, Krajewska, Urszula, Mirowski, Marek, Merecz-Sadowska, Anna, Karwowski, Bolesław T., Kusz, Joachim, Budzisz, Elzbieta

“…Three new arene ruthenium(II) complexes have been obtained. Their cytotoxic studies showed them to display moderate activity, however evaluation of their DNA…”
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