Search Results - "MIRJOLET, Céline"

Ionizing Radiation and the Immune Response - Part A by Galluzzi, Lorenzo, Mirjolet, Celine

“…Ionizing Radiation and the Immune Response, Volume 376, Part A reviews the latest updates on the immune response induced by ionizing radiations. Sections…”
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The radio-induced immune response: ballistics is key by Mirjolet, Céline, Baude, Jérémy

“…Whether the radio-induced immune response found after SRT also occurs after CRT remains unclear. [...]the objective of Tadepalli et al. was to study the…”
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Impact of proton therapy on antitumor immune response by Mirjolet, Céline, Nicol, Anaïs, Limagne, Emeric, Mura, Carole, Richard, Corentin, Morgand, Véronique, Rousseau, Marc, Boidot, Romain, Ghiringhelli, François, Noel, Georges, Burckel, Hélène

“…Radiotherapy delivered using photons induces an immune response that leads to modulation of the tumor microenvironment. Clinical studies are ongoing to…”
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The 6th R of Radiobiology: Reactivation of Anti-Tumor Immune Response by Boustani, Jihane, Grapin, Mathieu, Laurent, Pierre-Antoine, Apetoh, Lionel, Mirjolet, Céline

“…Historically, the 4Rs and then the 5Rs of radiobiology explained the effect of radiation therapy (RT) fractionation on the treatment efficacy. These 5Rs are:…”
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Optimized fractionated radiotherapy with anti-PD-L1 and anti-TIGIT: a promising new combination by Grapin, Mathieu, Richard, Corentin, Limagne, Emeric, Boidot, Romain, Morgand, Véronique, Bertaut, Aurélie, Derangere, Valentin, Laurent, Pierre-Antoine, Thibaudin, Marion, Fumet, Jean David, Crehange, Gilles, Ghiringhelli, François, Mirjolet, Céline

“…Radiotherapy (RT) induces an immunogenic antitumor response, but also some immunosuppressive barriers. It remains unclear how different fractionation protocols…”
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Dual impact of radiation therapy on tumor-targeting immune responses by Mirjolet, Céline, Baude, Jérémy, Galluzzi, Lorenzo

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Challenges in glioblastoma research: focus on the tumor microenvironment by Bikfalvi, Andreas, da Costa, Cristine Alves, Avril, Tony, Barnier, Jean-Vianney, Bauchet, Luc, Brisson, Lucie, Cartron, Pierre Francois, Castel, Hélène, Chevet, Eric, Chneiweiss, Hervé, Clavreul, Anne, Constantin, Bruno, Coronas, Valérie, Daubon, Thomas, Dontenwill, Monique, Ducray, Francois, Enz-Werle, Natacha, Figarella-Branger, Dominique, Fournier, Isabelle, Frenel, Jean-Sébastien, Gabut, Mathieu, Galli, Thierry, Gavard, Julie, Huberfeld, Gilles, Hugnot, Jean-Philippe, Idbaih, Ahmed, Junier, Marie-Pierre, Mathivet, Thomas, Menei, Philippe, Meyronet, David, Mirjolet, Céline, Morin, Fabrice, Mosser, Jean, Moyal, Elisabeth Cohen-Jonathan, Rousseau, Véronique, Salzet, Michel, Sanson, Marc, Seano, Giorgio, Tabouret, Emeline, Tchoghandjian, Aurélie, Turchi, Laurent, Vallette, Francois M, Vats, Somya, Verreault, Maité, Virolle, Thierry

“…Glioblastoma (GBM) is the most deadly type of malignant brain tumor, despite extensive molecular analyses of GBM cells. In recent years, the tumor…”
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Clinical and dosimetric study of radiotherapy for glioblastoma: three-dimensional conformal radiotherapy versus intensity-modulated radiotherapy by Thibouw, David, Truc, Gilles, Bertaut, Aurélie, Chevalier, Cédric, Aubignac, Léone, Mirjolet, Céline

“…Background and purpose We aimed to compare three-dimensional conformal radiotherapy (3D-CRT) with intensity-modulated radiotherapy (IMRT) for the treatment of…”
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HSP110 translocates to the nucleus upon genotoxic chemotherapy and promotes DNA repair in colorectal cancer cells by Causse, Sebastien Z., Marcion, Guillaume, Chanteloup, Gaëtan, Uyanik, Burhan, Boudesco, Christophe, Grigorash, Bogdan B., Douhard, Romain, Dias, Alexandre M. M., Dumetier, Baptiste, Dondaine, Lucile, Gozzi, Gustavo J., Moussay, Etienne, Paggetti, Jérôme, Mirjolet, Céline, de Thonel, Aurélie, Dubrez, Laurence, Demidov, Oleg N., Gobbo, Jessica, Garrido, Carmen

“…A multicenter clinical study demonstrated the presence of a loss-of-function HSP110 mutation in about 15% of colorectal cancers, which resulted from an…”
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Anti-PD-1/Anti-PD-L1 Drugs and Radiation Therapy: Combinations and Optimization Strategies by Boustani, Jihane, Lecoester, Benoît, Baude, Jérémy, Latour, Charlène, Adotevi, Olivier, Mirjolet, Céline, Truc, Gilles

“…Immune checkpoint inhibitors have been associated with long-term complete responses leading to improved overall survival in several cancer types. However,…”
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A phase I study of the combination of atezolizumab, tiragolumab, and stereotactic body radiation therapy in patients with metastatic multiorgan cancer by Roussot, Nicolas, Fumet, Jean-David, Limagne, Emeric, Thibaudin, Marion, Hervieu, Alice, Hennequin, Audrey, Zanetta, Sylvie, Dalens, Lorraine, Fourrier, Théo, Galland, Loick, Jacob, Pierre, Bertaut, Aurélie, Rederstorff, Emilie, Chevalier, Cédric, Ghirardi, Sarah, Gilbert, Elodie, Khoukaz, Azzat, Martin, Etienne, Nicolet, Constance, Quivrin, Magali, Thibouw, David, Vulquin, Noémie, Truc, Gilles, Rouffiac, Magali, Ghiringhelli, Francois, Mirjolet, Céline

“…Abstract Background Immunotherapy targeting the PD-1/PD-L1 pathway is a standard of care in a number of metastatic malignancies, but less than a fifth of…”
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Subcutaneous Administration of a Zwitterionic Chitosan‐Based Hydrogel for Controlled Spatiotemporal Release of Monoclonal Antibodies by Gréa, Thomas, Jacquot, Guillaume, Durand, Arthur, Mathieu, Clélia, Gasser, Adeline, Zhu, Chen, Banerjee, Mainak, Hucteau, Elyse, Mallard, Joris, Lopez Navarro, Pedro, Popescu, Bogdan V., Thomas, Eloise, Kryza, David, Sidi‐Boumedine, Jacqueline, Ferrauto, Giuseppe, Gianolio, Eliana, Fleith, Guillaume, Combet, Jérôme, Brun, Susana, Erb, Stéphane, Cianferani, Sarah, Charbonnière, Loïc J., Fellmann, Lyne, Mirjolet, Céline, David, Laurent, Tillement, Olivier, Lux, François, Harlepp, Sébastien, Pivot, Xavier, Detappe, Alexandre

“…Subcutaneous (SC) administration of monoclonal antibodies (mAbs) is a proven strategy for improving therapeutic outcomes and patient compliance. The current…”
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Treatment related factors associated with the risk of breast radio-induced-sarcoma by Mirjolet, Céline, Diallo, Ibrahima, Bertaut, Aurélie, Veres, Cristina, Sargos, Paul, Helfre, Sylvie, Sunyach, Marie-Pierre, Truc, Gilles, Le Pechoux, Cécile, Paumier, Amaury, Ducassou, Anne, Jolnerovski, Maria, Thariat, Juliette, Lapeyre, Michel, Cordoba, Abel, Mahé, Marc-André, Maingon, Philippe

“…•The RIS development area was almost always in full beam.•Reassuringly, new RT techniques such as VMAT should not have an impact on the incidence of…”
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Cisplatin-based chemoradiation decreases telomerase-specific CD4 TH1 response but increases immune suppressive cells in peripheral blood by Boustani, Jihane, Joseph, Elodie Lauret Marie, Martin, Etienne, Benhmida, Salim, Lecoester, Benoit, Tochet, Florent, Mirjolet, Céline, Chevalier, Cédric, Thibouw, David, Vulquin, Noémie, Servagi, Stéphanie, Sun, Xushan, Adotévi, Olivier

“…The synergistic effect of chemoradiation (CRT) has been previously demonstrated in several cancer types. Here, we investigated the systemic immune effects of…”
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Taxane‐Grafted Metal‐Oxide Nanoparticles as a New Theranostic Tool against Cancer: The Promising Example of Docetaxel‐Functionalized Titanate Nanotubes on Prostate Tumors by Loiseau, Alexis, Boudon, Julien, Mirjolet, Céline, Créhange, Gilles, Millot, Nadine

“…The combination of anticancer drugs and metal oxide nanoparticles is of great interest in cancer nanomedicine. Here, the development of a new nanohybrid,…”
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Titanate Nanotubes Engineered with Gold Nanoparticles and Docetaxel to Enhance Radiotherapy on Xenografted Prostate Tumors by Loiseau, Alexis, Boudon, Julien, Oudot, Alexandra, Moreau, Mathieu, Boidot, Romain, Chassagnon, Rémi, Saïd, Nasser Mohamed, Roux, Stéphane, Mirjolet, Céline, Millot, Nadine

“…Nanohybrids based on titanate nanotubes (TiONts) were developed to fight prostate cancer by intratumoral (IT) injection, and particular attention was paid to…”
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About the Influence of PEG Spacers on the Cytotoxicity of Titanate Nanotubes-Docetaxel Nanohybrids against a Prostate Cancer Cell Line by Loiseau, Alexis, Boudon, Julien, Mirjolet, Céline, Morgand, Véronique, Millot, Nadine

“…The association between chemotherapeutic drugs and metal oxide nanoparticles has sparked a rapidly growing interest in cancer nanomedicine. The elaboration of…”
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The role of telomeres in predicting individual radiosensitivity of patients with cancer in the era of personalized radiotherapy by Mirjolet, Céline, Boidot, Romain, Saliques, Sébastien, Ghiringhelli, François, Maingon, Philippe, Créhange, Gilles

“…Highlights • Telomeres play a role in the era of personalized radiotherapy. • Telomere length of cancer cells may be a reliable marker of radiotherapy…”
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Supramolecular Heterodimer Peptides Assembly for Nanoparticles Functionalization by Mathieu, Clélia, Ghosh, Shayamita, Draussin, Julien, Gasser, Adeline, Jacquot, Guillaume, Banerjee, Mainak, Gupta, Tanushree, Schmutz, Marc, Mirjolet, Céline, Tillement, Olivier, Lux, François, Klymchenko, Andrey S., Donzeau, Mariel, Pivot, Xavier, Harlepp, Sébastien, Detappe, Alexandre

“…Nanoparticle (NP) surface functionalization with proteins, including monoclonal antibodies (mAbs), mAb fragments, and various peptides, has emerged as a…”
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Predicting acute severe toxicity for head and neck squamous cell carcinomas by combining dosimetry with a radiosensitivity biomarker: a pilot study by Deneuve, Sophie, Bastogne, Thierry, Duclos, Mirlande, Mirjolet, Céline, Bois, Pascaline, Bachmann, Patrick, Nokovitch, Lara, Roux, Pierre-Eric, Girodet, Didier, Poupart, Marc, Zrounba, Philippe, Claude, Line, Ferella, Letizia, Iacovelli, Nicola Alessandro, Foray, Nicolas, Rancati, Tiziana, Pereira, Sandrine

“…Objective: Radiotherapy (RT) against head and neck squamous cell carcinomas (HNSCC) may lead to severe toxicity in 30-40% of patients. The normal tissue…”
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