Search Results - "MIODINI, Patrizia"

Analysis of Single Circulating Tumor Cells in Renal Cell Carcinoma Reveals Phenotypic Heterogeneity and Genomic Alterations Related to Progression by Cappelletti, Vera, Verzoni, Elena, Ratta, Raffaele, Vismara, Marta, Silvestri, Marco, Montone, Rosanna, Miodini, Patrizia, Reduzzi, Carolina, Claps, Melanie, Sepe, Pierangela, Daidone, Maria Grazia, Procopio, Giuseppe

“…Circulating tumor cells (CTCs) are promising biomarkers for prognosis, therapeutic response prediction, and treatment monitoring in cancer patients. Despite…”
Get full text

A phase II study evaluating the efficacy of enzalutamide and the role of liquid biopsy for evaluation of ARv7 in mCRPC patients with measurable metastases including visceral disease (Excalibur study) by Sepe, Pierangela, Procopio, Giuseppe, Pircher, Chiara Carlotta, Basso, Umberto, Caffo, Orazio, Cappelletti, Vera, Claps, Melanie, De Giorgi, Ugo, Fratino, Lucia, Guadalupi, Valentina, Miodini, Patrizia, De Marco, Cinzia, Perrucci, Bruno, Mennitto, Alessia, Santini, Daniele, Spina, Francesco, Stellato, Marco, de Braud, Filippo, Verzoni, Elena

“…Up to 30% of patients with metastatic castration-resistant prostate cancer (mCRPC) develop visceral metastases, which are associated with a poor prognosis…”
Get full text

Dissecting Time- from Tumor-Related Gene Expression Variability in Bilateral Breast Cancer by Callari, Maurizio, Dugo, Matteo, Miodini, Patrizia, Veneroni, Silvia, Bianchini, Giampaolo, Daidone, Maria Grazia, Cappelletti, Vera

“…Metachronous (MBC) and synchronous bilateral breast tumors (SBC) are mostly distinct primaries, whereas paired primaries and their local recurrences (LRC)…”
Get full text

Use of formalin-fixed paraffin-embedded samples for gene expression studies in breast cancer patients by Musella, Valeria, Callari, Maurizio, Di Buduo, Eleonora, Scuro, Manuela, Dugo, Matteo, Miodini, Patrizia, Bianchini, Giampaolo, Paolini, Biagio, Gianni, Luca, Daidone, Maria Grazia, Cappelletti, Vera

“…To obtain gene expression profiles from samples collected in clinical trials, we conducted a pilot study to assess feasibility and estimate sample attrition…”
Get full text

Prospective evaluation of estrogen receptor-β in predicting response to neoadjuvant antiestrogen therapy in elderly breast cancer patients by Cappelletti, Vera, Celio, Luigi, Bajetta, Emilio, Allevi, Arianna, Longarini, Raffaella, Miodini, Patrizia, Villa, Raffaella, Fabbri, Alessandra, Mariani, Luigi, Giovanazzi, Riccardo, Galante, Emanuele, Greco, Marco, Grazia Daidone, Maria

“…It has been proposed that knowledge of estrogen receptor β (ER-β) expression may refine estrogen receptor α (ER-α) predictivity of response to endocrine…”
Get full text

Metabolic Footprints and Molecular Subtypes in Breast Cancer by Dugo, Matteo, Silvestri, Marco, Miodini, Patrizia, Iorio, Egidio, Cappelletti, Vera, Daidone, Maria Grazia

“…Cancer treatment options are increasing. However, even among the same tumor histotype, interpatient tumor heterogeneity should be considered for best…”
Get full text

Single-Cell Phenotypic and Molecular Characterization of Circulating Tumor Cells Isolated from Cryopreserved Peripheral Blood Mononuclear Cells of Patients with Lung Cancer and Sarcoma by Vismara, Marta, Reduzzi, Carolina, Silvestri, Marco, Murianni, Fabio, Lo Russo, Giuseppe, Fortunato, Orazio, Motta, Rosita, Lanzoni, Davide, Giovinazzo, Francesca, Miodini, Patrizia, Pasquali, Sandro, Suatoni, Paola, Pastorino, Ugo, Roz, Luca, Sozzi, Gabriella, Cappelletti, Vera, Bertolini, Giulia

“…Abstract Background The isolation of circulating tumor cells (CTCs) requires rapid processing of the collected blood due to their inherent fragility. The…”
Get full text

A phase II study evaluating the efficacy of enzalutamide and the role of ARv7 in metastatic castration-resistant prostate cancer (mCRPC) patients (pts) with visceral disease by Sepe, Pierangela, Procopio, Giuseppe, Basso, Umberto, Caffo, Orazio, Cappelletti, Vera, Claps, Melanie, De Giorgi, Ugo, Fratino, Lucia, Guadalupi, Valentina, Miodini, Patrizia, Perrucci, Bruno, Mennitto, Alessia, Santini, Daniele, Spina, Francesco, Ottini, Arianna, De Braud, Filippo G., Verzoni, Elena

“…Abstract only 5052 Background: Enzalutamide is a second-generation androgen receptor inhibitor that showed to prolong survival in different setting of prostate…”
Get full text

Abstract 1747: A microenvironment gene signature predicts poor outcome in patients with luminal breast cancers subjected to local-regional treatment by Daidone, Maria Grazia, Merlino, Giuseppe, Miodini, Patrizia, Callari, Maurizio, Cappelletti, Vera

“…Abstract Gene expression studies, mainly addressed at the tumor cell compartment of breast cancers (BC) contributed to unravel the molecular heterogeneity…”
Get full text

Gene expression analysis reveals a different transcriptomic landscape in female and male breast cancer by Callari, Maurizio, Cappelletti, Vera, De Cecco, Loris, Musella, Valeria, Miodini, Patrizia, Veneroni, Silvia, Gariboldi, Manuela, Pierotti, Marco Alessandro, Daidone, Maria Grazia

“…Male breast cancer (MBC) is a poorly characterized disease because of its rarity. Clinical management is based on results obtained from randomized trials…”
Get full text

Abstract 1390: Molecular characterization of circulating tumor cells in cholangiocarcinoma patients: A new tool for treatment management by Reduzzi, Carolina, Vismara, Marta, Silvestri, Marco, Niger, Monica, Motta, Rosita, Peverelli, Giorgia, Miodini, Patrizia, Celio, Luigi, Braud, Filippo De, Daidone, Maria G., Cappelletti, Vera

“…Abstract BACKGROUND: Cholangiocarcinoma (CCA) is a highly fatal disease mainly treated with standard chemotherapy, albeit with limited efficacy. New…”
Get full text

Prognostic and functional role of subtype‐specific tumor–stroma interaction in breast cancer by Merlino, Giuseppe, Miodini, Patrizia, Callari, Maurizio, D'Aiuto, Francesca, Cappelletti, Vera, Daidone, Maria Grazia

“…None of the clinically relevant gene expression signatures available for breast cancer were specifically developed to capture the influence of the…”
Get full text

Could Circulating Tumor Cells and ARV7 Detection Improve Clinical Decisions in Metastatic Castration-Resistant Prostate Cancer? The Istituto Nazionale dei Tumori (INT) Experience by Sepe, Pierangela, Verzoni, Elena, Miodini, Patrizia, Claps, Melanie, Ratta, Raffaele, Martinetti, Antonia, Mennitto, Roberta, Sottotetti, Elisa, Procopio, Giuseppe, Cappelletti, Vera, Daidone, Maria Grazia

“…Enzalutamide and abiraterone have been shown to improve progression-free survival (PFS) and overall survival (OS) in metastatic castration-resistant prostate…”
Get full text

Subtype-dependent prognostic relevance of an interferon-induced pathway metagene in node-negative breast cancer by Callari, Maurizio, Musella, Valeria, Di Buduo, Eleonora, Sensi, Marialuisa, Miodini, Patrizia, Dugo, Matteo, Orlandi, Rosaria, Agresti, Roberto, Paolini, Biagio, Carcangiu, Maria Luisa, Cappelletti, Vera, Daidone, Maria Grazia

“…The majority of gene expression signatures developed to predict the likelihood to relapse in breast cancer (BC) patients assigns a high risk score to patients…”
Get full text

Development of a Protocol for Single-Cell Analysis of Circulating Tumor Cells in Patients with Solid Tumors by Reduzzi, Carolina, Motta, Rosita, Bertolini, Giulia, Miodini, Patrizia, Martinetti, Antonia, Sottotetti, Elisa, Daidone, Maria Grazia, Cappelletti, Vera

“…Genomic characterization of circulating tumor cells (CTCs) enables the monitoring of tumor progression and of adaption occurring during treatment. CTC…”
Get more information

Applicability of Under Vacuum Fresh Tissue Sealing and Cooling to Omics Analysis of Tumor Tissues by Veneroni, Silvia, Dugo, Matteo, Daidone, Maria Grazia, Iorio, Egidio, Valeri, Barbara, Pinciroli, Patrizia, De Bortoli, Maida, Marchesi, Edoardo, Miodini, Patrizia, Taverna, Elena, Ricci, Alessandro, Canevari, Silvana, Pelosi, Giuseppe, Bongarzone, Italia

“…Biobanks of frozen human normal and malignant tissues represent a valuable source for "omics" analysis in translational cancer research and molecular…”
Get more information

Proliferation-, estrogen-, and T-cell-related metagenes to predict outcome after adjuvant/neoadjuvant chemotherapy for operable breast cancer in the ECTO trial by Bianchini, Giampaolo, Cappelletti, Vera, Callari, Maurizio, Carcangiu, Maria Luisa, Eiermann, Wolfgang, Semiglazov, Vladimir, Guillem, Vicente, Lluch, Ana, Mansutti, Mauro, Zambetti, Milvia, Mariani, Gabriella, Magazzu, Domenico, Valagussa, Pinuccia, Paolini, Biagio, Musella, Valeria, Di Buduo, Eleonora, Miodini, Patrizia, Scuro, Manuela, Daidone, Maria Grazia, Gianni, Luca

“…Abstract only 1014 Background: Predicting recurrence in operable breast cancer (BC) despite optimal chemotherapy would be relevant to new drug development and…”
Get full text

Clusterin : A potential target for improving response to antiestrogens by TOFFANIN, Sara, GRAZIA DAIDONE, Maria, MIODINI, Patrizia, DE CECCO, Loris, GANDELLINI, Paolo, CAPPELLETTI, Vera

“…Antiestrogens represent the first line of therapy in the treatment of estrogen receptor-positive (ER+) breast cancer patients. Unfortunately, up to 40% of…”
Get full text

Modulation of estrogen receptor-β isoforms by phytoestrogens in breast cancer cells by CAPPELLETTI, Vera, MIODINI, Patrizia, DI FRONZO, Giovanni, DAIDONE, Maria Grazia

“…High consumption of phytoestrogen-rich food correlates with reduced incidence of breast cancer. However, the effect of phytoestrogens on growth of pre-existing…”
Get full text

Use of Formalin-Fixed Paraffin-Embedded Samples for Gene Expression Studies in Breast Cancer Patients: e0123194 by Musella, Valeria, Callari, Maurizio, Buduo, Eleonora Di, Scuro, Manuela, Dugo, Matteo, Miodini, Patrizia, Bianchini, Giampaolo, Paolini, Biagio, Gianni, Luca, Daidone, Maria Grazia

“…To obtain gene expression profiles from samples collected in clinical trials, we conducted a pilot study to assess feasibility and estimate sample attrition…”
Get full text