Search Results - "MINZHOU HUANG"

Adenosine triphosphate-based tumor chemosensitivity assay may predict the clinical outcomes of gastric cancer patients receiving taxane-based post-operative adjuvant chemotherapy by Bian, Yicong, Huang, Minzhou, Ma, Sheng, Liu, Linsheng, Xia, Fan, Chen, Zhiyao, Yu, Di, Huang, Chenrong, Miao, Liyan

“…[4,5] Furthermore, 59 patients who received standard gastrectomy and taxane-based post-operative chemotherapy regimens were followed up to obtain overall…”
Get full text

Dose escalation biodistribution, positron emission tomography/computed tomography imaging and dosimetry of a highly specific radionuclide-labeled non-blocking nanobody by Yang, Yanling, Wang, Chao, Wang, Yan, Sun, Yan, Huang, Xing, Huang, Minzhou, Xu, Hui, Fan, Huaying, Chen, Daquan, Zhao, Feng

“…Background Immunotherapy is a valuable option for cancer treatment, and the curative effect of anti-PD-1/PD-L1 therapy correlates closely with PD-L1 expression…”
Get full text

Role of RhoB in the Regulation of Pulmonary Endothelial and Smooth Muscle Cell Responses to Hypoxia by Wojciak-Stothard, Beata, Zhao, Lan, Oliver, Eduardo, Dubois, Olivier, Wu, Yixing, Kardassis, Dimitris, Vasilaki, Eleftheria, Huang, Minzhou, Mitchell, Jane A, Harrington, Louise S, Prendergast, George C, Wilkins, Martin R

“…RATIONALE:RhoA and Rho kinase contribute to pulmonary vasoconstriction and vascular remodeling in pulmonary hypertension. RhoB, a protein homologous to RhoA…”
Get full text

Therapeutic Characterization of 131I-Labeled Humanized Anti-B7-H3 Antibodies for Radioimmunotherapy for Glioblastoma by Fu, Fengqing, Zheng, Meng, Zhao, Shandong, Wang, Yan, Huang, Minzhou, Chen, Hanqing, Huang, Ziyi, Zhang, Kaijie, Miao, Liyan, Zhang, Xueguang

“…B7 homolog 3 (B7-H3) has attracted much attention in glioblastoma (GBM) radioimmunotherapy (RIT) due to its abnormally high expression on tumor cells. In this…”
Get full text

RhoB Regulates PDGFR-β Trafficking and Signaling in Vascular Smooth Muscle Cells by Huang, Minzhou, DuHadaway, James B, Prendergast, George C, Laury-Kleintop, Lisa D

“…OBJECTIVE—RhoB is a small GTPase localized at the plasma membrane and endosomes that participates in the regulation of endocytic trafficking of the epidermal…”
Get full text

RhoB Differentially Controls Akt Function in Tumor Cells and Stromal Endothelial Cells during Breast Tumorigenesis by KAZEROUNIAN, Shiva, GERALD, Damien, PHUNG, Thuy L, BRAVO-NUEVO, Arturo, SHECHTER, Sharon, MCNAMARA, Stephanie, DUHADAWAY, James B, KOCHER, Olivier N, BROWN, Lawrence F, TOKER, Alex, PRENDERGAST, George C, BENJAMIN, Laura E, MINZHOU HUANG, REBECCA CHIN, Y, UDAYAKUMAR, Durga, NINGNING ZHENG, O'DONNELL, Rebekah K, PERRUZZI, Carole, MANGIANTE, Lee, POURAT, Jacob

“…Tumors are composed of cancer cells but also a larger number of diverse stromal cells in the tumor microenvironment. Stromal cells provide essential supports…”
Get full text

Meglumine exerts protective effects against features of metabolic syndrome and type II diabetes by Bravo-Nuevo, Arturo, Marcy, Alice, Huang, Minzhou, Kappler, Frank, Mulgrew, Jennifer, Laury-Kleintop, Lisa, Reichman, Melvin, Tobia, Annette, Prendergast, George C

“…Metabolic syndrome, diabetes and diabetes complications pose a growing medical challenge worldwide, accentuating the need of safe and effective strategies for…”
Get full text

Mammalian CARMIL Inhibits Actin Filament Capping by Capping Protein by Yang, Changsong, Pring, Martin, Wear, Martin A., Huang, Minzhou, Cooper, John A., Svitkina, Tatyana M., Zigmond, Sally H.

“…Actin polymerization in cells occurs via filament elongation at the barbed end. Proteins that cap the barbed end terminate this elongation. Heterodimeric…”
Get full text

Profilin Enhances Cdc42-Induced Nucleation of Actin Polymerization by Yang, Changsong, Huang, Minzhou, DeBiasio, John, Pring, Martin, Joyce, Michael, Miki, Hiroaki, Takenawa, Tadaomi, Zigmond, Sally H.

“…We find that profilin contributes in several ways to Cdc42-induced nucleation of actin filaments in high speed supernatant of lysed neutrophils. Depletion of…”
Get full text

Bin3 Deletion Causes Cataracts and Increased Susceptibility to Lymphoma during Aging by RAMALINGAM, Arivudainambi, DUHADAWAY, James B, MULLER, Alexander J, DUNCAN, Melinda K, PRENDERGAST, George C, SUTANTO-WARD, Erika, YAN WANG, DINCHUK, Joseph, MINZHOU HUANG, DONOVER, Preston S, BOULDEN, Janette, MCNALLY, Lois M, SOLER, Alejandro P

“…Bin3 encodes an evolutionarily conserved and ubiquitously expressed member of the BAR superfamily of curved membrane and GTPase-binding proteins, which…”
Get full text

Cyclin B1 is a critical target of RhoB in the cell suicide program triggered by farnesyl transferase inhibition by KAMASANI, Uma, MINZHOU HUANG, DUHADAWAY, James B, PROCHOWNIK, Edward V, DONOVER, P. Scott, PRENDERGAST, George C

“…Farnesyl transferase inhibitors (FTIs) have displayed limited efficacy in clinical trials, possibly because of their relatively limited cytotoxic effects…”
Get full text

Pilot study of a novel nanobody 68 Ga-NODAGA-SNA006 for instant PET imaging of CD8+ T cells by Wang, Yan, Wang, Chao, Huang, Minzhou, Qin, Songbing, Zhao, Jun, Sang, Shibiao, Zheng, Meng, Bian, Yicong, Huang, Chenrong, Zhang, Hua, Guo, Lingchuan, Jiang, Jiwei, Xu, Chun, Dai, Na, Zheng, Yushuang, Han, Jiajun, Yang, Min, Xu, Tao, Miao, Liyan

“…Purpose Positron emission tomography (PET) with specific diagnostic probes for quantifying CD8 + T cells has emerged as a powerful technique for monitoring the…”
Get full text

Adenosine triphosphate-based tumor chemosensitivity assay may predict the clinical outcomes of gastric cancer patients receiving taxane-based post-operative adjuvant chemotherapy by Bian, Yicong, Huang, Minzhou, Ma, Sheng, Liu, Linsheng, Xia, Fan, Chen, Zhiyao, Yu, Di, Huang, Chenrong, Miao, Liyan

Get full text

RhoB links PDGF signaling to cell migration by coordinating activation and localization of Cdc42 and Rac by Huang, Minzhou, Satchell, Lauren, DuHadaway, James B., Prendergast, George C., Laury-Kleintop, Lisa D.

“…The small GTPase RhoB regulates endocytic trafficking of receptor tyrosine kinases (RTKs) and the non‐receptor kinases Src and Akt. While receptor‐mediated…”
Get full text

Isolation of a novel IgG from a patient with lung cancer using immunoassays and cloning by Dessain, Scott K., Borghaei, Hossein, Zhang, Jiping, Simon, Paul, Huang, Minzhou, Zhao, Huiwu, Puligedda, Rama Devudu, Murphy, Maureen E.

“…Abstract only e22163 Background: Cancer cells express novel antigens that are characteristic of the transformed state and may engender an immune response (…”
Get full text

Role of RhoB in the regulation of pulmonary endothelial and smooth muscle responses to hypoxia by Wojciak-Stothard, Beata, Yixing, Wu, Kardassis, Dimitris, Vasilaki, Eleftheria, Huang, Minzhou, Prendergast, George

Get full text

Mechanism of Cdc42-Induced Actin Polymerization in Neutrophil Extracts by Zigmond, Sally H., Joyce, Michael, Yang, Changsong, Brown, Kevin, Huang, Minzhou, Pring, Martin

“…Cdc42, activated with GTPγS, induces actin polymerization in supernatants of lysed neutrophils. This polymerization, like that induced by agonists, requires…”
Get full text

Cdc42-induced actin filaments are protected from capping protein by Huang, Minzhou, Yang, Changsong, Schafer, Dorothy A., Cooper, John A., Higgs, Henry N., Zigmond, Sally H.

“…Each actin filament has a pointed and a barbed end, however, filament elongation occurs primarily at the barbed end. Capping proteins, by binding to the barbed…”
Get full text

Presence of a novel inhibitor of capping protein in neutrophil extract by Huang, Minzhou, Pring, Martin, Yang, Changsong, Taoka, Masato, Zigmond, Sally H.

“…Capping of actin filament barbed ends regulates the duration of filament elongation and the steady‐state level of actin polymerization. We find that the…”
Get full text