Search Results - "MINKLER, J. L"

Validation of chromosome painting as a biodosimeter in human peripheral lymphocytes following acute exposure to ionizing radiation in vitro by Tucker, J D, Ramsey, M J, Lee, D A, Minkler, J L

“…Fluorescence in situ hybridization with chromosome-specific composite DNA probes ('chromosome painting') appears to be a useful tool for quantifying…”
Get more information

The development of chromosome-specific composite DNA probes for the mouse and their application to chromosome painting by BRENEMAN, J. W, RAMSEY, M. J, LEE, D. A, EVELETH, G. G, MINKLER, J. L, TUCKER, J. D

“…The speed and ease of human cytogenetic analysis has been greatly enhanced by the technique of fluorescence in situ hybridization (FISH). Non-radioactive…”
Get full text

Sister chromatid exchange as an indicator of mutagenesis by CARRANO, A. V, THOMPSON, L. H, LINDL, P. A, MINKLER, J. L

Get full text

The development of painting probes for dual-color and multiple chromosome analysis in the mouse by Breneman, J W, Swiger, R R, Ramsey, M J, Minkler, J L, Eveleth, J G, Langlois, R A, Tucker, J D

“…The recent development of mouse chromosome painting probes for fluorescence in situ hybridization has extended the use of this common laboratory mammal in…”
Get more information

Biological Effectiveness of Neutrons from Hiroshima Bomb Replica: Results of a Collaborative Cytogenetic Study by Dobson, R. L., Straume, T., Carrano, A. V., Minkler, J. L., Deaven, L. L., Littlefield, L. G., Awa, A. A.

“…The effectiveness of neutrons from a facsimile of the Hiroshima bomb was determined cytogenetically. The "Little-Boy" replica (LBR), assembled at Los Alamos as…”
Get full text

DNA-mediated transfer of a human DNA repair gene that controls sister chromatid exchange by THOMPSON, L. H, BROOKMAN, K. W, MINKLER, J. L, FUSCOE, J. C, HENNING, K. A, CARRANO, A. V

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Metabolic activation and cytogenetic effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) in Chinese hamster ovary cells expressing murine cytochrome P450 IA2 by Buonarati, M H, Tucker, J D, Minkler, J L, Wu, R W, Thompson, L H, Felton, J S

“…We have utilized Chinese hamster ovary cell lines which stably express a murine cytochrome P450IA2 (P(3)450) cDNA to characterize more fully the mechanisms of…”
Get more information

Identification of nucleotide-excision-repair genes on human chromosomes 2 and 13 by functional complementation in hamster-human hybrids by THOMPSON, L. H, CARRANO, A. V, SATO, K, SALAZAR, E. P, WHITE, B. F, STEWART, S. A, MINKLER, J. L, SICILIANO, M. J

“…The CHO UV-sensitive mutants UV24 and UV135 (complementation groups 3 and 5, respectively) are defective in nucleotide excision repair. After fusing each…”
Get full text

Purification of the chromosomes of the Indian muntjac by flow sorting by Carrano, AV, Gray, JW, Moore, DH, 2d, Minkler, JL, Mayall, BH, van Dilla, MA, Mendelsohn, ML

“…Metaphase chromosomes were isolated from a male Indian muntjac cell line, were stained with ethidium bromide and were analyzed by flow microfluorometry to…”
Get full text

Incorporated bromodeoxyuridine enhances the sister-chromatid exchange and chromosomal aberration frequencies in an EMS-sensitive Chinese hamster cell line by Carrano, A V, Minkler, J L, Dillehay, L E, Thompson, L H

“…The mutant Chinese hamster cell line, EM9, is characterized by a high baseline sister-chromatid exchange (SCE) frequency, increased sensitivity to cell…”
Get more information

DNA crosslinking, sister-chromatid exchange and specific-locus mutations by Carrano, A V, Thompson, L H, Stetka, D G, Minkler, J L, Mazrimas, J A, Fong, S

“…Chinese hamster ovary cells were treated with the DNA-crosslinking chemicals, mitomycin C (MMC) and porfiromycin (POR), and their monofunctional derivative…”
Get more information

Variation in the baseline sister chromatid exchange frequency in human lymphocytes by Carrano, A V, Minkler, J L, Stetka, D G, Moore, 2nd, D H

“…The utility of the sister chromatid exchange (SCE) assay for human population studies is potentially limited by the variability associated with individual…”
Get more information

A CHO-cell strain having hypersensitivity to mutagens, a defect in DNA strand-break repair, and an extraordinary baseline frequency of sister-chromatid exchange by Thompson, L H, Brookman, K W, Dillehay, L E, Carrano, A V, Mazrimas, J A, Mooney, C L, Minkler, J L

“…A mutant of CHO cells (strain EM9) previously isolated on the basis of hypersensitivity to killing by ethyl methanesulfonate (EMS) is approx. 10-fold more…”
Get more information

Variation in baseline sister chromatid exchange frequencies in humans by Carrano, A V, Ashworth, L K, Minkler, J L, Moore, 2nd, D H

Get more information

A Specific Common Chromosomal Pathway for the Origin of Human Malignancy-II by Minkler, J L, Gofman, J W, Tandy, R K

“…A consistent chromosome abnormality exists in 17 human cell lines and in 11 fresh cancers, a finding strongly supportive of our original support of Boveri's…”
Get full text

In vivo cytogenetic effects of the cooked-food-related mutagens Trp-P-2 and IQ in mouse bone marrow by Minkler, J L, Carrano, A V

“…Sister-chromatid exchange and chromosomal aberrations were measured in vivo in mouse bone marrow following intraperitoneal injection of the cooked food…”
Get more information

A specific common chromosomal pathway for the origin of human malignancy. II. Evaluation of long-term human hazards of potential environmental carcinogens by Minkler, J L, Gofman, J W, Tandy, R K

Get more information

In vivo exposure to plant flavonols. Influence on frequencies of micronuclei in mouse erythrocytes and sister-chromatid exchange in rabbit lymphocytes by MacGregor, J T, Wehr, C M, Manners, G D, Jurd, L, Minkler, J L, Carrano, A V

“…No consistent increases in the micronucleus frequency were observed in bone marrow or peripheral blood erythrocytes from mice treated with quercetin,…”
Get more information

The relationship between sister-chromatid exchange and perturbations in DNA replication in mutant EM9 and normal CHO cells by Dillehay, L E, Thompson, L H, Minkler, J L, Carrano, A V

“…The majority of the high (12-fold elevated) baseline sister-chromatid exchanges (SCEs) that occur in the CHO mutant line EM9 appear to be a consequence of…”
Get more information

A long-term effect of radiation on chromosomes of cultured human fibroblasts by Minkler, J L, Piluso, D, Gofman, J W, Tandy, R K

Get more information