Search Results - "MING, Marin"
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An in vitro functional assay to measure the biological activity of TB vaccine candidate H4-IC31
Published in Vaccine (16-05-2019)“…•In vitro assay measures biological activity of vaccine in human PBMC.•H4-IC31 stimulates PBMC IFNγ secretion in cells from BCG-immunized individual.•Assay…”
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Epitope Profiling of Diphtheria Toxoid Provides Enhanced Monitoring for Consistency Testing during Manufacturing Process Changes
Published in Vaccines (Basel) (13-05-2022)“…In the vaccine industry, multiple physicochemical, immunological, and analytical methods are applied throughout the manufacturing process to characterize and…”
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Formulation development of a stable influenza recombinant neuraminidase vaccine candidate
Published in Human vaccines & immunotherapeutics (31-12-2024)“…Current influenza vaccines could be augmented by including recombinant neuraminidase (rNA) protein antigen to broaden protective immunity and improve efficacy…”
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Development of an In Vitro Test Method to Replace an Animal-Based Potency Test for Pertactin Antigen in Multivalent Vaccines
Published in Vaccines (Basel) (27-01-2023)“…There is increasing interest to replace animal-based potency assays used routinely to test vaccines, since they are highly variable, are costly, and present…”
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Neutralizing Antibodies Elicited by a Novel Detoxified Pneumolysin Derivative, PlyD1, Provide Protection against Both Pneumococcal Infection and Lung Injury
Published in Infection and Immunity (01-06-2012)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Flow cytometry: An efficient method for antigenicity measurement and particle characterization on an adjuvanted vaccine candidate H4-IC31 for tuberculosis
Published in Journal of immunological methods (01-01-2018)“…We have developed an accurate, precise and stability-indicating flow cytometry (FC) based assay to directly measure antigenicity of H4 protein (also known as…”
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Replacing the in vivo toxin challenge test with an in vitro assay for assessment of potency for diphtheria toxoid containing vaccines
Published in Biologicals (01-11-2020)“…Replacement of the potency tests for diphtheria vaccines is a high priority for the international initiative to reduce, refine, and replace animal use in…”
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Formulation, stability and immunogenicity of a trivalent pneumococcal protein vaccine formulated with aluminum salt adjuvants
Published in Vaccine (19-04-2012)“…Highlights ► We studied the immunogenicity and stability a pneumococcal vaccine in Al adjuvants. ► Immunogenicity was significantly higher in AlO(OH) compared…”
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Induction of CTL responses by plasmid DNA immunization
Published 01-01-1999“…A novel method of vaccination has recently been discovered, and is based on the ability of injected plasmid DNA to be taken up and expressed by cells in situ…”
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Dissertation -
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Passive protection of mice against Streptococcus pneumoniae challenge by naturally occurring and vaccine-induced human anti-PhtD antibodies
Published in Human vaccines & immunotherapeutics (03-07-2015)“…Currently marketed Streptococcus pneumoniae vaccines are based on polysaccharide capsular antigens from the most common strains. Pneumococcal histidine triad…”
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Journal Article