Search Results - "MINE, Yasuhiro"

Investigation of Food Characteristics Modulating Spoon Motions in Skilled Spoon Users: Proposal of a Control Target for the Active Self-feeding Spoon by Yasuda, Toshitaka, Fukiwake, Midori, Shimokasa, Kenji, Mine, Yasuhiro

“…The present study proposes control target for the motion of an active self-feeding spoon by analyzing skilled spoon motions reflecting the grasping actions of…”
Get full text

In vitro antibacterial activity of FK037, a novel parenteral broad-spectrum cephalosporin by Mine, Y, Watanabe, Y, Sakamoto, H, Hatano, K, Kuno, K, Higashi, Y, Kamimura, T, Matsumoto, Y, Tawara, S, Matsumoto, F

“…FK037 is a new parenteral cephalosporin, which offers some advantages over the commercially available parenteral cephalosporins. It demonstrated potent…”
Get more information

Excellent activity of FK037, a novel parenteral broad-spectrum cephalosporin, against methicillin-resistant staphylococci by Mine, Y, Watanabe, Y, Sakamoto, H, Hatano, K, Kuno, K, Kamimura, T, Tawara, S, Matsumoto, Y, Matsumoto, F, Kuwahara, S

“…FK037 exhibits potent in vitro and in vivo antibacterial activity against methicillin-resistant staphylococci. In in vitro studies, FK037 was the most active…”
Get more information

Detection of DNA lesions induced by chemical mutagens by the single cell gel electrophoresis (Comet) assay by Miyamae, Youichi, Zaizen, Kazuyo, Ohara, Kaname, Mine, Yasuhiro, Sasaki, Yu F

Get full text

In vivo antibacterial activity of FK037, a novel parenteral broad-spectrum cephalosporin by Mine, Y, Watanabe, Y, Sakamoto, H, Hatano, K, Wakai, Y, Kamimura, T, Tawara, S, Matsumoto, S, Matsumoto, F, Kuwahara, S

“…FK037 has potent therapeutic activity against lethal systemic infections and experimental local infections due to a wide variety of Gram-positive and…”
Get more information

Animal pharmacokinetics of FK037, a novel parenteral broad-spectrum cephalosporin by Sakamoto, H, Hatano, K, Higashi, Y, Mine, Y, Nakamoto, S, Tawara, S, Kamimura, T, Matsumoto, F, Kuwahara, S

“…Single-dose pharmacokinetics of FK037 has been investigated in laboratory animals. After bolus intravenous dosing with 20 mg/kg, the elimination half-life of…”
Get more information

In vitro antibacterial activity of FK482, a new orally active cephalosporin by Mine, Y, Kamimura, T, Watanabe, Y, Tawara, S, Matsumoto, Y, Shibayama, F, Kikuchi, H, Takaya, T, Kuwahara, S

“…FK482 is a new orally active cephem antibiotic which offers some advantages over the commercially available oral beta-lactam antibiotics. It displayed a broad…”
Get more information

Pharmacokinetics of FK027 in rats and dogs by Sakamoto, H, Hirose, T, Mine, Y

“…The pharmacokinetics of FK027, a new oral cephalosporin, were investigated in rats and dogs and compared with those of cefaclor, cephalexin and amoxicillin…”
Get more information

TACROLIMUS (FK506)-INDUCED NEPHROTOXICITY IN SPONTANEOUS HYPERTENSIVE RATS by MITAMURA, Takashi, YAMADA, Atsushi, ISHIDA, Hisao, FUJIHIRA, Shiro, OHARA, Kaname, NOGUCHI, Hideyo, MINE, Yasuhiro

“…To clarify the profile of the tacrolimus (FK506)-induced nephrotoxicity and its mechanism, 1, 2 and 4 mg/kg/day of tacrolimus was administered intramuscularly…”
Get full text

MECHANISM OF FK506-INDUCED GLUCOSE INTOLERANCE IN RATS by HIRANO, Yuri, MITAMURA, Takashi, TAMURA, Takayuki, OHARA, Kaname, MINE, Yasuhiro, NOGUCHI, Hideyo

“…To clarify the mechanism of glucose intolerance induced by FK506, a novel immunosuppressant, 5 or 10 mg/kg/day of FK506 was dosed orally to rats for 2 weeks,…”
Get full text

Effect of cisplatin on erythropoietin production in rats by UNAMI, Akira, NISHINA, Noriko, TERAI, Takao, SATO, Susumu, TAMURA, Takayuki, NODA, Kohsei, MINE, Yasuhiro

Get full text

Protective effects of immunoactive peptide, FK565 against systemic and local infections with herpes simplex virus and murine cytomegalovirus and respiratory tract infection with influenza virus in mice by Yokota, Y, Watanabe, Y, Wakai, Y, Mine, Y

“…The protective effects of FK565 against systemic infections with herpes simplex virus (HSV) and murine cytomegalovirus (MCMV), respiratory tract infection with…”
Get more information

MUTAGENICITY TESTS OF POLYOXYETHYLENE HYDROGENATED CASTOR OIL 60 (HCO-60) by HIRAI, Osamu, MIYAMAE, Youichi, ZAIZEN, Kazuyo, MIYAMOTO, Astushi, TAKASHIMA, Miyuki, HATTORI, Yuko, OHARA, Kaname, MINE, Yasuhiro

“…The genotoxicity of polyoxyethylene hydrogenated castor oil 60 (HCO-60) was examined in reverse mutation test in bacteria, chromosome aberration test in vitro…”
Get full text

Inhibitory effect of FK-565 alone and in combination with zidovudine on retroviral infection by Friend leukemia virus in mice by Yokota, Y, Wakai, Y, Watanabe, Y, Mine, Y

“…The effects of route and starting time of administration on FK-565 inhibition of splenomegaly by Friend leukemia virus (FLV) were studied in mice, and the…”
Get more information

Pharmacokinetics of FK482, a new orally active cephalosporin, in animals by Sakamoto, H, Hirose, T, Nakamoto, S, Hatano, K, Shibayama, F, Kikuchi, H, Mine, Y, Kuwahara, S

“…The pharmacokinetic profile of FK482 was studied in mice, rats, rabbits and dogs after oral dosing and compared with that of cefixime, cefaclor and cephalexin…”
Get more information

Biphenomycins A and B, novel peptide antibiotics. I. Taxonomy, fermentation, isolation and characterization by Ezaki, M, Iwami, M, Yamashita, M, Hashimoto, S, Komori, T, Umehara, K, Mine, Y, Kohsaka, M, Aoki, H, Imanaka, H

“…Biphenomycin A, C23H28N4O8, and biphenomycin B, C23H28N4O7, were isolated from the cultured broth of Streptomyces griseorubiginosus No. 43708. The antibiotics…”
Get more information

In vitro and in vivo Transferrable β-Lactam Resistance Due to a New Plasmid-Mediated Oxyiminocephalosporinase from a Clinical Isolate of Proteus mirabilis by Watanabe, Yuji, Yokota, Takeshi, Higashi, Yasuyuki, Wakai, Yoshimi, Mine, Yasuhiro

“…A new plasmid-mediated β-lactamase (FPM-1) with an isoelectric point of 7.2 and a molecular weight of 26, 000 was found in a cefuroxime-resistant clinical…”
Get full text

In vivo antibacterial activity of FK482, a new orally active cephalosporin by Mine, Y, Yokota, Y, Wakai, Y, Kamimura, T, Tawara, S, Shibayama, F, Kikuchi, H, Kuwahara, S

“…The therapeutic activities of orally administered FK482 were compared with those of reference antibiotics against systemic and local infections with a variety…”
Get more information

Nature of Monocyclic β-Lactam Antibiotic Nocardicin A to β-Lactamases by Kojo, Hitoshi, Mine, Yasuhiro, Nishida, Minoru, Goto, Sachiko, Kuwahara, Shogo

“…Nocardicin A is the antibiotic which was first found to possess a monocyclic β-lactam ring. This antibiotic was inactivated by the cleavage of its β-lactam…”
Get full text

Synergism of cephalosporins at subinhibitory concentrations and polymorphonuclear leukocytes on phagocytic killing of Escherichia coli and its mode of action by Watanabe, Y, Tawara, S, Mine, Y, Kikuchi, H, Goto, S, Kuwahara, S

“…The interactions between subinhibitory concentrations of cephalosporins and polymorphonuclear leukocytes in the killing of a strain of Escherichia coli are…”
Get more information