Search Results - "MINAMI, KOICHIRO"

Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation by Iske, Jasper, Seyda, Midas, Heinbokel, Timm, Maenosono, Ryoichi, Minami, Koichiro, Nian, Yeqi, Quante, Markus, Falk, Christine S., Azuma, Haruhito, Martin, Friederike, Passos, João F., Niemann, Claus U., Tchkonia, Tamara, Kirkland, James L., Elkhal, Abdallah, Tullius, Stefan G.

“…Older organs represent an untapped potential to close the gap between demand and supply in organ transplantation but are associated with age-specific responses…”
Get full text

MicroRNA‐143/Musashi‐2/KRAS cascade contributes positively to carcinogenesis in human bladder cancer by Tsujino, Takuya, Sugito, Nobuhiko, Taniguchi, Kohei, Honda, Ryo, Komura, Kazumasa, Yoshikawa, Yuki, Takai, Tomoaki, Minami, Koichiro, Kuranaga, Yuki, Shinohara, Haruka, Tokumaru, Yoshihisa, Heishima, Kazuki, Inamoto, Teruo, Azuma, Haruhito, Akao, Yukihiro

“…It has been well established that microRNA (miR)‐143 is downregulated in human bladder cancer (BC). Recent precision medicine has shown that mutations in BC…”
Get full text

microRNA-145 Mediates the Inhibitory Effect of Adipose Tissue-Derived Stromal Cells on Prostate Cancer by Takahara, Kiyoshi, Ii, Masaaki, Inamoto, Teruo, Nakagawa, Takatoshi, Ibuki, Naokazu, Yoshikawa, Yuki, Tsujino, Takuya, Uchimoto, Taizo, Saito, Kenkichi, Takai, Tomoaki, Tanda, Naoki, Minami, Koichiro, Uehara, Hirofumi, Komura, Kazumasa, Hirano, Hajime, Nomi, Hayahito, Kiyama, Satoshi, Asahi, Michio, Azuma, Haruhito

“…Adipose-derived stromal cell (ASC), known as one of the mesenchymal stem cells (MSCs), is a promising tool for regenerative medicine; however, the effect of…”
Get more information

Labeling of target mRNAs using a photo-reactive microRNA probe by Nakamoto, Kosuke, Minami, Koichiro, Akao, Yukihiro, Ueno, Yoshihito

“…To identify target mRNAs of an miRNA, we synthesized photo-reactive miRNA probes, which contained a photo-reactive nucleoside analog,…”
Get more information

Taurodeoxycholic acid and valine reverse obesity‐associated augmented alloimmune responses and prolong allograft survival by Quante, Markus, Iske, Jasper, Uehara, Hirofumi, Minami, Koichiro, Nian, Yeqi, Maenosono, Ryochi, Matsunaga, Tomohisa, Liu, Yang, Azuma, Haruhito, Perkins, David, Alegre, Maria‐Luisa, Zhou, Hao, Elkhal, Abdallah, Tullius, Stefan G.

“…Obesity initiates a chronic inflammatory network linked to perioperative complications and increased acute rejection rates in organ transplantation. Bariatric…”
Get full text

MiR-145 negatively regulates Warburg effect by silencing KLF4 and PTBP1 in bladder cancer cells by Minami, Koichiro, Taniguchi, Kohei, Sugito, Nobuhiko, Kuranaga, Yuki, Inamoto, Teruo, Takahara, Kiyoshi, Takai, Tomoaki, Yoshikawa, Yuki, Kiyama, Satoshi, Akao, Yukihiro, Azuma, Haruhito

“…The Warburg effect is a well-known feature in cancer-specific metabolism. We previously reported on the role of microRNA (miR)-145 as a tumor-suppressor in…”
Get full text

μ-Opioid Receptor Forms a Functional Heterodimer With Cannabinoid CB1 Receptor: Electrophysiological and FRET Assay Analysis by Hojo, Minoru, Sudo, Yuka, Ando, Yuko, Minami, Koichiro, Takada, Masafumi, Matsubara, Takehiro, Kanaide, Masato, Taniyama, Kohtaro, Sumikawa, Koji, Uezono, Yasuhito

“…Interactions between μ-opioid receptor (μOR) and cannabinoid CB1 receptor (CB1R) were examined by morphological and electrophysiological methods. In baby…”
Get full text

C-reactive protein-albumin ratio as a prognostic factor in renal cell carcinoma – A data from multi-institutional study in Japan by Tsujino, Takuya, Komura, Kazumasa, Hashimoto, Takeshi, Muraoka, Ryu, Satake, Naoya, Matsunaga, Tomohisa, Tsutsumi, Takeshi, Yoshikawa, Yuki, Takai, Tomoaki, Minami, Koichiro, Uehara, Hirofumi, Hirano, Hajime, Nomi, Hayahito, Ibuki, Naokazu, Takahara, Kiyoshi, Inamoto, Teruo, Ohno, Yoshio, Azuma, Haruhito

“…•A multi-institutional cohort of 699 patients who underwent nephrectomy was investigated in the study.•The Youden index offered an optimal cut-off value of…”
Get full text

A Novel Combination RNAi toward Warburg Effect by Replacement with miR-145 and Silencing of PTBP1 Induces Apoptotic Cell Death in Bladder Cancer Cells by Takai, Tomoaki, Yoshikawa, Yuki, Inamoto, Teruo, Minami, Koichiro, Taniguchi, Kohei, Sugito, Nobuhiko, Kuranaga, Yuki, Shinohara, Haruka, Kumazaki, Minami, Tsujino, Takuya, Takahara, Kiyoshi, Ito, Yuko, Akao, Yukihiro, Azuma, Haruhito

“…Bladder cancer is one of the most difficult malignancies to control. We explored the use of a novel RNA-interference method for a driver oncogene regulating…”
Get full text

Adipose-derived stromal cells inhibit prostate cancer cell proliferation inducing apoptosis by Takahara, Kiyoshi, Ii, Masaaki, Inamoto, Teruo, Komura, Kazumasa, Ibuki, Naokazu, Minami, Koichiro, Uehara, Hirofumi, Hirano, Hajime, Nomi, Hayahito, Kiyama, Satoshi, Asahi, Michio, Azuma, Haruhito

“…•AdSC transplantation exhibits inhibitory effect on tumor progressions of PCa cells.•AdSC-induced PCa cell apoptosis may occur via the TGF-β signaling…”
Get full text

The CANLPH Score, an Integrative Model of Systemic Inflammation and Nutrition Status (SINS), Predicts Clinical Outcomes After Surgery in Renal Cell Carcinoma: Data From a Multicenter Cohort in Japan by Komura, Kazumasa, Hashimoto, Takeshi, Tsujino, Takuya, Muraoka, Ryu, Tsutsumi, Takeshi, Satake, Naoya, Matsunaga, Tomohisa, Yoshikawa, Yuki, Takai, Tomoaki, Minami, Koichiro, Taniguchi, Kohei, Uehara, Hirofumi, Tanaka, Tomohito, Hirano, Hajime, Nomi, Hayahito, Ibuki, Naokazu, Takahara, Kiyoshi, Inamoto, Teruo, Ohno, Yoshio, Azuma, Haruhito

“…Background A myriad of studies have demonstrated the clinical association of systemic inflammatory and nutrition status (SINS) including C-reactive…”
Get full text

Preoperative Measurement of the Modified Glasgow Prognostic Score Predicts Patient Survival in Non-Metastatic Renal Cell Carcinoma Prior to Nephrectomy by Tsujino, Takuya, Komura, Kazumasa, Matsunaga, Tomohisa, Yoshikawa, Yuki, Takai, Tomoaki, Uchimoto, Taizo, Saito, Kenkichi, Tanda, Naoki, Oide, Rintaro, Minami, Koichiro, Uehara, Hirofumi, Jeong, Seong Ho, Taniguchi, Kohei, Hirano, Hajime, Nomi, Hayahito, Ibuki, Naokazu, Takahara, Kiyoshi, Inamoto, Teruo, Azuma, Haruhito

“…Purpose The modified Glasgow Prognostic Score (mGPS) by measurement of serum C-reactive protein and albumin levels has been shown to provide prognostic value…”
Get full text

Carboplatin Enhances the Activity of Human Transient Receptor Potential Ankyrin 1 through the Cyclic AMP-Protein Kinase A-A-Kinase Anchoring Protein (AKAP) Pathways by Miyano, Kanako, Shiraishi, Seiji, Minami, Koichiro, Sudo, Yuka, Suzuki, Masami, Yokoyama, Toru, Terawaki, Kiyoshi, Nonaka, Miki, Murata, Hiroaki, Higami, Yoshikazu, Uezono, Yasuhito

“…Carboplatin, an anticancer drug, often causes chemotherapy-induced peripheral neuropathy (PN). Transient receptor potential ankyrin 1 (TRPA1), a non-selective…”
Get full text

Distinct effect of body mass index by sex as a prognostic factor in localized renal cell carcinoma treated with nephrectomy ~ data from a multi-institutional study in Japan by Tsutsumi, Takeshi, Komura, Kazumasa, Hashimoto, Takeshi, Muraoka, Ryu, Satake, Naoya, Matsunaga, Tomohisa, Tsujino, Takuya, Yoshikawa, Yuki, Takai, Tomoaki, Minami, Koichiro, Taniguchi, Kohei, Tanaka, Tomohito, Uehara, Hirofumi, Hirano, Hajime, Nomi, Hayahito, Ibuki, Naokazu, Takahara, Kiyoshi, Inamoto, Teruo, Ohno, Yoshio, Azuma, Haruhito

“…We assessed the prognostic value of body mass index (BMI) in Asian patients with localized RCC who underwent nephrectomy. A total of 665 patients who underwent…”
Get full text

Adjuvant chemotherapy improves overall survival in patients with localized upper tract urothelial carcinoma harboring pathologic vascular invasion: a propensity score-matched analysis of multi-institutional cohort by Matsunaga, Tomohisa, Komura, Kazumasa, Hashimoto, Takeshi, Muraoka, Ryu, Satake, Naoya, Tsutsumi, Takeshi, Tsujino, Takuya, Yoshikawa, Yuki, Takai, Tomoaki, Minami, Koichiro, Taniguchi, Kohei, Tanaka, Tomohito, Uehara, Hirofumi, Hirano, Hajime, Nomi, Hayahito, Ibuki, Naokazu, Takahara, Kiyoshi, Inamoto, Teruo, Ohno, Yoshio, Azuma, Haruhito

“…Objective Whether adjuvant chemotherapy (AC) for patients with upper tract urothelial carcinoma (UTUC) offers survival benefit is still controversial. To…”
Get full text

Tetramodal therapy using balloon-occluded arterial infusion of anticancer agents, the Azuma regimen, for lymph node-involved bladder cancer by Azuma, Haruhito, Inamoto, Teruo, Takahara, Kiyoshi, Ibuki, Naokazu, Nomi, Hayahito, Komura, Kazumasa, Uehara, Hirofumi, Minami, Koichiro, Yamamoto, Kazuhiro, Narumi, Yoshifumi

“…Overall, >900 patients have been treated at Osaka Medical College (Takatsuki, Osaka, Japan) using the novel approach of balloon-occluded arterial infusion…”
Get full text

The combination of preoperative platelet count and neutrophil lymphocyte ratio as a prognostic indicator in localized renal cell carcinoma by Tsujino, Takuya, Komura, Kazumasa, Ichihashi, Atsushi, Tsutsumi, Takeshi, Matsunaga, Tomohisa, Yoshikawa, Yuki, Maenosono, Ryoichi, Okita, Kyohei, Takai, Tomoaki, Oide, Rintaro, Minami, Koichiro, Uehara, Hirofumi, Taniguchi, Kohei, Hirano, Hajime, Nomi, Hayahito, Ibuki, Naokazu, Takahara, Kiyoshi, Inamoto, Teruo, Azuma, Haruhito

“…The combination of platelet count and neutrophil to lymphocyte ratio (COP-NLR) has been shown to provide prognostic information in several cancers, whereas its…”
Get full text

Prognostic impact of C-reactive protein-albumin ratio for the lethality in castration-resistant prostate cancer by Uchimoto, Taizo, Komura, Kazumasa, Fujiwara, Yuya, Saito, Kenkichi, Tanda, Naoki, Matsunaga, Tomohisa, Ichihashi, Atsushi, Tsutsumi, Takeshi, Tsujino, Takuya, Yoshikawa, Yuki, Nishimoto, Yudai, Takai, Tomoaki, Minami, Koichiro, Taniguchi, Kohei, Tanaka, Tomohito, Uehara, Hirofumi, Hirano, Hajime, Nomi, Hayahito, Ibuki, Naokazu, Takahara, Kiyoshi, Inamoto, Teruo, Azuma, Haruhito

“…This study aimed to assess the clinical value of C-reactive protein-albumin ratio (CAR) at the initiation of first-line treatment for castration-resistant…”
Get full text

Recipient sex and estradiol levels affect transplant outcomes in an age-specific fashion by Maenosono, Ryoichi, Nian, Yeqi, Iske, Jasper, Liu, Yang, Minami, Koichiro, Rommel, Tabea, Martin, Friederike, Abdi, Reza, Azuma, Haruhito, Rosner, Bernhard A., Zhou, Hao, Milford, Edgar, Elkhal, Abdallah, Tullius, Stefan G.

Get full text

The Anti-Proliferative Effect of Boron Neutron Capture Therapy in a Prostate Cancer Xenograft Model by Takahara, Kiyoshi, Inamoto, Teruo, Minami, Koichiro, Yoshikawa, Yuki, Takai, Tomoaki, Ibuki, Naokazu, Hirano, Hajime, Nomi, Hayahito, Kawabata, Shinji, Kiyama, Satoshi, Miyatake, Shin-Ichi, Kuroiwa, Toshihiko, Suzuki, Minoru, Kirihata, Mitsunori, Azuma, Haruhito

“…Boron neutron capture therapy (BNCT) is a selective radiation treatment for tumors that preferentially accumulate drugs carrying the stable boron isotope, 10B…”
Get full text