Search Results - "MINAMI, AKIHIRO"

Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth by Cox, Andrew G., Hwang, Katie L., Brown, Kristin K., Evason, Kimberley J., Beltz, Sebastian, Tsomides, Allison, O’Connor, Keelin, Galli, Giorgio G., Yimlamai, Dean, Chhangawala, Sagar, Yuan, Min, Lien, Evan C., Wucherpfennig, Julia, Nissim, Sahar, Minami, Akihiro, Cohen, David E., Camargo, Fernando D., Asara, John M., Houvras, Yariv, Stainier, Didier Y. R., Goessling, Wolfram

“…The Hippo pathway is an important regulator of organ size and tumorigenesis. It is unclear, however, how Hippo signalling provides the cellular building blocks…”
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Downregulation of CXCR4 in Metastasized Breast Cancer Cells and Implication in Their Dormancy by Nobutani, Kentaro, Shimono, Yohei, Mizutani, Kiyohito, Ueda, Yuki, Suzuki, Toshihiro, Kitayama, Midori, Minami, Akihiro, Momose, Kenji, Miyawaki, Kohta, Akashi, Koichi, Azuma, Takeshi, Takai, Yoshimi

“…Our understanding of the mechanism of cancer dormancy is emerging, but the underlying mechanisms are not fully understood. Here we analyzed mouse xenograft…”
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Association of adverse childhood experiences and cortical neurite density alterations with posttraumatic stress disorder symptoms in autism spectrum disorder by Kitamura, Soichiro, Matsuoka, Kiwamu, Takahashi, Masato, Yoshikawa, Hiroaki, Minami, Akihiro, Ohnishi, Hiroki, Ishida, Rio, Miyasaka, Toshiteru, Tai, Yumi, Ochi, Tomoko, Tanaka, Toshihiro, Makinodan, Manabu

“…Background Posttraumatic stress disorder (PTSD) can be a source of significant social and daily distress in autism spectrum disorder (ASD). Compared to…”
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Absence of primary cilia in cell cycle‐arrested human breast cancer cells by Nobutani, Kentaro, Shimono, Yohei, Yoshida, Midori, Mizutani, Kiyohito, Minami, Akihiro, Kono, Seishi, Mukohara, Toru, Yamasaki, Takashi, Itoh, Tomoo, Takao, Shintaro, Minami, Hironobu, Azuma, Takeshi, Takai, Yoshimi

“…Previous studies using cultured cells showed that primary cilia are present in quiescent cells, but are absent in proliferating cells. We studied here the…”
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Suppression of the TGF‐β1‐induced protein expression of SNAI1 and N‐cadherin by miR‐199a by Suzuki, Toshihiro, Mizutani, Kiyohito, Minami, Akihiro, Nobutani, Kentaro, Kurita, Souichi, Nagino, Masato, Shimono, Yohei, Takai, Yoshimi

“…MicroRNA miR‐199a is clustered with miR‐214 on chromosome 1 and its expression is up‐regulated by various factors that are associated with…”
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Metabolomics-based search for therapeutic agents for non-alcoholic steatohepatitis by Terashima, Yoshihiko, Nishiumi, Shin, Minami, Akihiro, Kawano, Yuki, Hoshi, Namiko, Azuma, Takeshi, Yoshida, Masaru

“…•We subjected liver of MCD diet-induced steatohepatitis model to metabolome analysis.•Hypotaurine exhibited the greatest decrease in hepatic concentration in…”
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miR‐214 and hypoxia down‐regulate Necl‐2/CADM1 and enhance ErbB2/ErbB3 signaling by Momose, Kenji, Minami, Akihiro, Shimono, Yohei, Mizutani, Kiyohito, Nobutani, Kentaro, Azuma, Takeshi, Takai, Yoshimi

“…Necl‐2/CADM1 is down‐regulated by the promoter hypermethylation and/or the loss of heterozygosity at chromosome 11q23.2 in many types of cancers and serves as…”
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Significance of post‐progression therapy after tyrosine kinase inhibitors for advanced hepatocellular carcinoma by Yano, Yoshihiko, Yamamoto, Atsushi, Minami, Akihiro, Momose, Kenji, Mimura, Takuya, Kim, Soo Ki, Hayashi, Hiroki, Kado, Takuo, Hirano, Hirotaka, Hirohata, Seiya, Yoon, Seitetsu, Nishi, Katsuhisa, Tei, Hiroshi, Tanaka, Hidenori, Oouchi, Sachiko, Matsuura, Takanori, Yasutomi, Eiichiro, Hatazawa, Yuri, Shiomi, Yuuki, Ueda, Yoshihide, Kodama, Yuzo

“…Background and Aim Molecular‐targeted therapies such as sorafenib and lenvatinib have long been used as first‐line treatment for advanced hepatocellular…”
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Factors associated with the response to atezolizumab/bevacizumab combination therapy for hepatocellular carcinoma by Yano, Yoshihiko, Yamamoto, Atsushi, Mimura, Takuya, Kushida, Saeko, Hirohata, Seiya, Yoon, Seitetsu, Hirano, Hirotaka, Kim, Soo Ki, Hatazawa, Yuri, Momose, Kenji, Hayashi, Hiroki, Kado, Takuo, Nishi, Katsuhisa, Tanaka, Hidenori, Matsuura, Takanori, Yoshida, Ryutaro, Asaji, Naoki, Yasutomi, Eiichiro, Shiomi, Yuuki, Minami, Akihiro, Komatsu, Shohei, Fukumoto, Takumi, Ueda, Yoshihide, Kodama, Yuzo

“…Background and Aim The purpose of this study was to analyze factors associated with the overall survival (OS) of atezolizumab/bevacizumab combination therapy…”
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Quasispecies variant of pre-S/S gene in HBV-related hepatocellular carcinoma with HBs antigen positive and occult infection by Hatazawa, Yuri, Yano, Yoshihiko, Okada, Rina, Tanahashi, Toshihito, Hayashi, Hiroki, Hirano, Hirotaka, Minami, Akihiro, Kawano, Yuki, Tanaka, Motofumi, Fukumoto, Takumi, Murakami, Yoshiki, Yoshida, Masaru, Hayashi, Yoshitake

“…Hepatocellular carcinoma (HCC) can develop in patients who are negative for the hepatitis B surface antigen (HBsAg) in serum but positive for hepatitis B virus…”
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Branched-chain Amino Acid Granules Improve the Non-protein Respiratory Quotient after Radiofrequency Ablation by Saito, Masaya, Yano, Yoshihiko, Minami, Akihiro, Hirano, Hirotaka, Momose, Kenji, Sugimoto, Maki, Yoshida, Masaru, Azuma, Takeshi

“…Objective The supplementation of oral branched-chain amino acid (BCAA) granules is known to improve energy metabolism in cirrhotic patients, but not those with…”
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Localization of nectin-free afadin at the leading edge and its involvement in directional cell movement induced by platelet-derived growth factor by Miyata, Muneaki, Ogita, Hisakazu, Komura, Hitomi, Nakata, Shinsuke, Okamoto, Ryoko, Ozaki, Misa, Majima, Takashi, Matsuzawa, Naomi, Kawano, Satoshi, Minami, Akihiro, Waseda, Masumi, Fujita, Naoyuki, Mizutani, Kiyohito, Rikitake, Yoshiyuki, Takai, Yoshimi

“…Afadin is an actin-filament-binding protein that binds to nectin, an immunoglobulin-like cell-cell adhesion molecule, and plays an important role in the…”
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Autoimmune-associated Hemophagocytic Syndrome Originating from Autoimmune Hepatitis with a Successful Response to Therapy by Saito, Masaya, Yano, Yoshihiko, Minami, Akihiro, Momose, Kenji, Hirano, Hirotaka, Yamasaki, Takashi, Itoh, Tomoo, Yoshida, Masaru, Azuma, Takeshi

“…The patient was a 15-year-old girl with severe acute hepatitis. A liver biopsy showed the typical findings of autoimmune hepatitis (AIH). Subsequently, two…”
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Necl‐5/PVR enhances PDGF‐induced attraction of growing microtubules to the plasma membrane of the leading edge of moving NIH3T3 cells by Minami, Akihiro, Mizutani, Kiyohito, Waseda, Masazumi, Kajita, Mihoko, Miyata, Muneaki, Ikeda, Wataru, Takai, Yoshimi

“…Microtubules (MTs) search for and grow toward the leading edge of moving cells, followed by their stabilization at a specific structure at the rear site of the…”
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Mutational diversity of NS5A and NS3 during triple therapy (telaprevir, pegylated-interferon-α 2b and ribavirin) for genotype 1b chronic hepatitis C: The Kobe Hepatitis Therapeutic Group by BAI, FUGUI, YANO, YOSHIHIKO, KIM, SOO-RYANG, SEO, YASUSHI, MIKI, AKIRA, SAITO, MASAYA, HIRANO, HIROTAKA, MOMOSE, KENJI, MINAMI, AKIHIRO, HATAZAWA, YURI, HAYAKUMO, TAKANOBU, WIDASARI, DEWIYANI INDAH, RINONCE, HANGGORO TRI, SUGANO, MASAHIKO, TANI, SATOSHI, YOON, SEITETSU, IMOTO, SUSUMU, AZUMA, TAKESHI, HOTTA, HAK, HAYASHI, YOSHITAKE

“…Telaprevir, a non-structural (NS)3/4A protease inhibitor, is a direct-acting antiviral drug that inhibits viral replication. Triple therapy with telaprevir,…”
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Effects of simulation conditions on evaluation of tool temperature in hot extrusion-forging by Minami, Akihiro, Marumo, Yasuo, Saiki, Hiroyuki, Ruan, Liqun, Shizuma, Osamu

“…High thermal loading causes severe wear and plastic deformation at the tool corners in hot forging. The quick evaluation of temperature in the tool surface…”
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β-hydroxybutyrate protects hepatocytes against endoplasmic reticulum stress in a sirtuin 1-independent manner by Tagawa, Ryoma, Kawano, Yuki, Minami, Akihiro, Nishiumi, Shin, Yano, Yoshihiko, Yoshida, Masaru, Kodama, Yuzo

“…β-hydroxybutyrate (BHB), a major ketone body in mammals, is produced from fatty acids through mitochondrial fatty acid oxidation in hepatocytes. To elucidate…”
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Current Status of Conversion Hepatectomy After Sorafenib and Lenvatinib Treatment for Unresectable Hepatocellular Carcinoma by Komatsu, Shohei, Yano, Yoshihiko, Mimura, Takuya, Minami, Akihiro, Momose, Kenji, Hirano, Hirotaka, Tanaka, Motofumi, Ueda, Yuki, Tai, Kentaro, Yasuhara, Yuki, Nakagawa, Daisuke, Yamamoto, Atsushi, Kido, Masahiro, Ueda, Yoshihide, Kodama, Yuzo, Fukumoto, Takumi

“…Sorafenib and lenvatinib have long been used as a first-line treatment for advanced hepatocellular carcinoma (HCC). Along with the development of systemic…”
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Reduction of the ST6 β-Galactosamide α-2,6-Sialyltransferase 1 (ST6GAL1)-catalyzed Sialylation of Nectin-like Molecule 2/Cell Adhesion Molecule 1 and Enhancement of ErbB2/ErbB3 Signaling by MicroRNA-199a by Minami, Akihiro, Shimono, Yohei, Mizutani, Kiyohito, Nobutani, Kentaro, Momose, Kenji, Azuma, Takeshi, Takai, Yoshimi

“…Nectin-like molecule 2 (Necl-2)/cell adhesion molecule 1 (CADM1) is shown to be down-regulated by the promoter hypermethylation and/or loss of heterozygosity…”
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Survey on Antibody against Parapoxvirus among Cattle in Japan by Sentsui, Hiroshi, Inoshima, Yasuo, Minami, Akihiro, Yamamoto, Yasunori, Murakami, Kenji, Shimizu, Shinya

“…A seroepidemiological survey was performed on antibody against parapoxvirus among cattle in Japan using the agar gel immunodiffusion test and enzyme-linked…”
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