Search Results - "MILLIGAN, PAUL E."

Clinical classification schemes for predicting hemorrhage: Results from the National Registry of Atrial Fibrillation (NRAF) by Gage, Brian F., Yan, Yan, Milligan, Paul E., Waterman, Amy D., Culverhouse, Robert, Rich, Michael W., Radford, Martha J.

“…Although warfarin and other anticoagulants can prevent ischemic events, they can cause hemorrhage. Quantifying the rate of hemorrhage is crucial for…”
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Genetic-based dosing in orthopedic patients beginning warfarin therapy by Millican, Eric A., Lenzini, Petra A., Milligan, Paul E., Grosso, Leonard, Eby, Charles, Deych, Elena, Grice, Gloria, Clohisy, John C., Barrack, Robert L., Burnett, R. Stephen J., Voora, Deepak, Gatchel, Susan, Tiemeier, Amy, Gage, Brian F.

“…High variability in drug response and a narrow therapeutic index complicate warfarin therapy initiation. No existing algorithm provides recommendations on…”
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Use of pharmacogenetics and clinical factors to predict the maintenance dose of warfarin by Gage, Brian F, Eby, Charles, Milligan, Paul E, Banet, Gerald A, Duncan, Jill R, McLeod, Howard L

“…Knowledge of pharmacogenetics may help clinicians predict their patients' therapeutic dose of warfarin, thereby decreasing the risk of bleeding during warfarin…”
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Prospective dosing of warfarin based on cytochrome P-450 2C9 genotype by Voora, Deepak, Eby, Charles, Linder, Mark W, Milligan, Paul E, Bukaveckas, Bonny L, McLeod, Howard L, Maloney, William, Clohisy, John, Burnett, R Steven, Grosso, Leonard, Gatchel, Susan K, Gage, Brian F

“…Cytochrome P-450 2C9 (CYP2C9) polymorphisms (CYP2C9*2 and CYP2C9*3) reduce the clearance of warfarin, increase the risk of bleeding, and prolong the time to…”
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Efficacy and safety of high-dose thromboprophylaxis in morbidly obese inpatients by Wang, Tzu-Fei, Milligan, Paul E, Wong, Catherine A, Deal, Eli N, Thoelke, Mark S, Gage, Brian F

“…Obesity increases the risk for venous thromboembolism (VTE), but whether high-dose thromboprophylaxis is safe and effective in morbidly obese inpatients is…”
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Effect of warfarin nonadherence on control of the International Normalized Ratio by Waterman, AD, Milligan, PE, Bayer, L, Banet, GA, Gatchel, SK, Gage, BF

“…The frequency and causes of ab- errant International Normalized Ratios (INRs) in warfarin recipients and the percentage explainable by warfarin nonadherence…”
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Case Study: Continuous Bedside Capnography Monitoring of High-Risk Patients Receiving Opioids by Milligan, Paul E, Zhang, Yao, Graver, Sally

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Maximal dose-response of vitamin-K2 (menaquinone-4) on undercarboxylated osteocalcin in women with osteoporosis by K Giri, Tusar, Newton, David, Chaudhary, Opal, Deych, Elena, Napoli, Nicola, Villareal, Reina, Diemer, Kathy, E Milligan, Paul, F Gage, Brian

“…Low concentrations of serum vitamin K accompany high concentrations of undercarboxylated osteocalcin (ucOC) and osteoporotic fractures. Although vitamin K2…”
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Warfarin dose reduction vs watchful waiting for mild elevations in the international normalized ratio by Banet, Gerald A, Waterman, Amy D, Milligan, Paul E, Gatchel, Susan K, Gage, Brian F

“…Whether clinicians should decrease the warfarin dose in response to a mild, asymptomatic elevation in the international normalized ratio (INR) is unknown. The…”
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Risk factors for inpatient venous thromboembolism despite thromboprophylaxis by Wang, Tzu-Fei, Wong, Catherine A, Milligan, Paul E, Thoelke, Mark S, Woeltje, Keith F, Gage, Brian F

“…Abstract Introduction Venous thromboembolism (VTE) is the most common preventable cause of morbidity and mortality in the hospital. Adequate thromboprophylaxis…”
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Multifaceted approach to reducing occurrence of severe hypoglycemia in a large healthcare system by Milligan, Paul E, Bocox, Mary C, Pratt, Elizabeth, Hoehner, Christine M, Krettek, John E, Dunagan, Wm Claiborne

“…PURPOSE.Substantial reductions in inpatient episodes of severe hypoglycemia achieved by a large healthcare system through enhanced use of technology and…”
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Optimal Initial Dose Adjustment of Warfarin in Orthopedic Patients by Lenzini, Petra A, Grice, Gloria R, Milligan, Paul E, Gatchel, Susan K, Deych, Elena, Eby, Charles S, Burnett, R Stephen J, Clohisy, John C, Barrack, Robert L, Gage, Brian F

“…Warfarin sodium is commonly prescribed for the prophylaxis and treatment of venous thromboembolism. Dosing algorithms have not been widely adopted because they…”
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Pharmacology and pharmacogenetics of warfarin and other coumarins when used with supplements by Gage, Brian F., Milligan, Paul E.

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Reducing medication prescribing errors in a teaching hospital by Garbutt, Jane, Milligan, Paul E, McNaughton, Candace, Highstein, Gabrielle, Waterman, Brian M, Dunagan, W Claiborne, Fraser, Victoria J

“…Medication errors occur frequently, result in significant morbidity and mortality, and are often preventable. A multifaceted intervention was conducted to…”
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Patient and Physician Satisfaction with a Telephone‐based Anticoagulation Service by Waterman, Amy D., Banet, Gerald, Milligan, Paul E., Frazier, Andrea, Verzino, Ellen, Walton, Brian, Gage, Brian F.

“…OBJECTIVES: To compare the satisfaction and knowledge of patients who have their warfarin managed by their physician or by a multidisciplinary, telephone‐based…”
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Substitution of Generic Warfarin for Coumadin in an HMO Setting by Milligan, Paul E, Banet, Gerald A, Waterman, Amy D, Gatchel, Susan K, Gage, Brian F

“…BACKGROUND: Substitution of generic warfarin for Coumadin presents safety concerns due to warfarin's narrow therapeutic index and because a prior generic…”
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Perioperative reduction of the warfarin dose by Milligan, Paul E, Banet, Gerald A, Gage, Brian F

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Pharmacogenetic dose adjustments in orthopedic patients beginning warfarin therapy by Jacobsen-Lenzini, Petra A., Eby, Charles S., Milligan, Paul E., Grice, Gloria R., Deych, Elena, Grosso, Leonard, Millican, Eric, Gatchel, Susan K., Clohisy, John C., Barrack, Robert L., Gage, Brian F.

“…Issue Title: Special issue on Proceedings of the 9th National Conference on Anticoagulant Therapy. Sponsored by the Anticoagulation Forum…”
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Risk factors for bleeding in patients taking coumarins by Beyth, Rebecca J, Milligan, Paul E, Gage, Brian F

“…Coumarins (e.g., warfarin) are used for the treatment and prophylaxis of venous and arterial thromboembolism. Unfortunately, their use is limited by bleeding…”
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A Practical Approach to Measure the Quality of Handwritten Medication Orders: A Tool for Improvement by Garbutt, Jane, Milligan, Paul E., McNaughton, Candace, Waterman, Brian M., Dunagan, Claiborne, Fraser, Victoria J.

“…Objective: System level solutions to reduce prescribing errors are not yet widely implemented and prescribing errors commonly occur in hand written orders. We…”
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