Search Results - "MILLER, Karen K"
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The endocrine manifestations of anorexia nervosa: mechanisms and management
Published in Nature reviews. Endocrinology (01-03-2017)“…Key Points Anorexia nervosa is associated with endocrine dysregulation, including dysfunction of the hypothalamic–pituitary axis and alterations in adipokines…”
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Sex differences in body composition and association with cardiometabolic risk
Published in Biology of sex differences (27-06-2018)“…Body composition differs between men and women, with women having proportionally more fat mass and men more muscle mass. Although men and women are both…”
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Visceral Fat Is a Negative Predictor of Bone Density Measures in Obese Adolescent Girls
Published in The journal of clinical endocrinology and metabolism (01-03-2010)“…Context: Regional fat is increasingly recognized as a determinant of bone mineral density (BMD), an association that may be mediated by adipokines, such as…”
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Increased Bone Marrow Fat in Anorexia Nervosa
Published in The journal of clinical endocrinology and metabolism (01-06-2009)“…Context: Although women with anorexia nervosa (AN) have severe depletion of body fat, a paradoxical increase in bone marrow fat has been described. Recent data…”
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Effect of Testosterone on Natriuretic Peptide Levels
Published in Journal of the American College of Cardiology (26-03-2019)“…Circulating natriuretic peptide (NP) levels are markedly lower in healthy men than women. A relative NP deficiency in men could contribute to their higher risk…”
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Deficits in volumetric bone mineral density, bone microarchitecture, and estimated bone strength in women with atypical anorexia nervosa compared to healthy controls
Published in The International journal of eating disorders (01-04-2024)“…Objective Anorexia nervosa is associated with low bone mineral density (BMD) and deficits in bone microarchitecture and strength. Low BMD is common in atypical…”
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Influence of Sex and Hormone Status on Circulating Natriuretic Peptides
Published in Journal of the American College of Cardiology (02-08-2011)“…Objectives The aim of this study was to assess the relationship between sex hormones and natriuretic peptide levels in community-based adults. Background Women…”
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Determinants of bone mineral density in obese premenopausal women
Published in Bone (New York, N.Y.) (01-04-2011)“…Abstract Despite being a risk factor for cardiovascular disease and diabetes mellitus, obesity has been thought to protect against osteoporosis. However,…”
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Plasma Free Cortisol in States of Normal and Altered Binding Globulins: Implications for Adrenal Insufficiency Diagnosis
Published in The journal of clinical endocrinology and metabolism (01-10-2019)“…Abstract Context Accurate diagnosis of adrenal insufficiency is critical because there are risks associated with overdiagnosis and underdiagnosis. Data using…”
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Atrial natriuretic peptide is negatively regulated by microRNA-425
Published in The Journal of clinical investigation (01-08-2013)“…Numerous common genetic variants have been linked to blood pressure, but no underlying mechanism has been elucidated. Population studies have revealed that the…”
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Lower Oxytocin Levels Are Associated with Lower Bone Mineral Density and Less Favorable Hip Geometry in Hypopituitary Men
Published in Neuroendocrinology (01-12-2020)“…Hypopituitary patients are at risk for bone loss. Hypothalamic-posterior pituitary hormones oxytocin and vasopressin are anabolic and catabolic, respectively,…”
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Physiologic Transdermal Estradiol Replacement Mimics Effects of Endogenous Estrogen on Bone Outcomes in Hypoestrogenic Women with Anorexia Nervosa
Published in Nutrients (21-06-2022)“…Background: While physiologic estrogen replacement results in increases in areal bone mineral density (aBMD) in hypoestrogenic adolescent girls and young adult…”
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Accuracy of Late-Night Salivary Cortisol in Evaluating Postoperative Remission and Recurrence in Cushing's Disease
Published in The journal of clinical endocrinology and metabolism (01-10-2015)“…Context: Late-night salivary cortisol (LNSC) is well-validated in the diagnosis of Cushing's disease (CD). The accuracy of LNSC during follow-up of patients…”
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Association between muscle mass and diabetes prevalence independent of body fat distribution in adults under 50 years old
Published in Nutrition & diabetes (28-05-2022)“…Background/objectives Although relatively less muscle mass has been associated with greater diabetes prevalence, whether there is an association between muscle…”
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Bone Density, Geometry, Structure and Strength Estimates in Adolescent and Young Adult Women with Atypical Anorexia Nervosa versus Typical Anorexia Nervosa and Normal-Weight Healthy Controls
Published in Nutrients (01-09-2023)“…Our objective was to characterize bone outcomes in adolescent and young adult women with atypical anorexia nervosa (AAN) compared to typical AN and…”
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Fibroblast Growth Factor-21 May Mediate Growth Hormone Resistance in Anorexia Nervosa
Published in The journal of clinical endocrinology and metabolism (01-01-2010)“…Context: Anorexia nervosa (AN), a state of chronic nutritional deprivation, is characterized by GH resistance with elevated GH levels and decreased levels of…”
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Recruitment strategies to increase racial and ethnic diversity in anorexia nervosa clinical research
Published in Journal of eating disorders (15-07-2023)“…Inclusion of underrepresented racial and ethnic groups in eating disorder (ED) research is a critical unmet need, but evidence-based recruitment strategies are…”
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The Upregulation of Molecules Related to Tumor Immune Escape in Human Pituitary Adenomas
Published in Frontiers in endocrinology (Lausanne) (21-10-2021)“…Human pituitary adenomas are one of the most common intracranial neoplasms. Although most of these tumors are benign and can be treated medically or by…”
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Low oxytocin levels are broadly associated with more pronounced psychopathology in anorexia nervosa with primarily restricting but not binge/purge eating behavior
Published in Frontiers in endocrinology (Lausanne) (31-01-2023)“…Anorexia nervosa (AN) is commonly associated with depression, anxiety, and deficits in socioemotional functioning. Basal levels of oxytocin, a neurohormone…”
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