Search Results - "MILLER, Chad"

Homing in: Mechanisms of Substrate Targeting by Protein Kinases by Miller, Chad J., Turk, Benjamin E.

“…Protein phosphorylation is the most common reversible post-translational modification in eukaryotes. Humans have over 500 protein kinases, of which more than a…”
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Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates by Egan, Daniel F., Chun, Matthew G.H., Vamos, Mitchell, Zou, Haixia, Rong, Juan, Miller, Chad J., Lou, Hua Jane, Raveendra-Panickar, Dhanya, Yang, Chih-Cheng, Sheffler, Douglas J., Teriete, Peter, Asara, John M., Turk, Benjamin E., Cosford, Nicholas D.P., Shaw, Reuben J.

“…Many tumors become addicted to autophagy for survival, suggesting inhibition of autophagy as a potential broadly applicable cancer therapy. ULK1/Atg1 is the…”
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Quantitative Determination of Organic Semiconductor Microstructure from the Molecular to Device Scale by Rivnay, Jonathan, Mannsfeld, Stefan C. B, Miller, Chad E, Salleo, Alberto, Toney, Michael F

“…Rivnay et al examine quantitative determination of organic semiconductor microstructure from the molecular to device scale…”
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A Comprehensive Mathematical Model for Three-Body Binding Equilibria by Douglass, Eugene F, Miller, Chad J, Sparer, Gerson, Shapiro, Harold, Spiegel, David A

“…Three-component systems are often more complex than their two-component counterparts. Although the reversible association of three components in solution is…”
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Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling by Creixell, Pau, Schoof, Erwin M., Simpson, Craig D., Longden, James, Miller, Chad J., Lou, Hua Jane, Perryman, Lara, Cox, Thomas R., Zivanovic, Nevena, Palmeri, Antonio, Wesolowska-Andersen, Agata, Helmer-Citterich, Manuela, Ferkinghoff-Borg, Jesper, Itamochi, Hiroaki, Bodenmiller, Bernd, Erler, Janine T., Turk, Benjamin E., Linding, Rune

“…Cancer cells acquire pathological phenotypes through accumulation of mutations that perturb signaling networks. However, global analysis of these events is…”
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Manipulating the Morphology of P3HT–PCBM Bulk Heterojunction Blends with Solvent Vapor Annealing by Verploegen, Eric, Miller, Chad E, Schmidt, Kristin, Bao, Zhenan, Toney, Michael F

“…Using grazing incidence X-ray scattering, we observe the effects of solvent vapors upon the morphology of poly(3-hexylthiophene)–phenyl-C61-butyric acid methyl…”
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Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output by Miller, Chad J, Lou, Hua Jane, Simpson, Craig, van de Kooij, Bert, Ha, Byung Hak, Fisher, Oriana S, Pirman, Natasha L, Boggon, Titus J, Rinehart, Jesse, Yaffe, Michael B, Linding, Rune, Turk, Benjamin E

“…Specificity within protein kinase signaling cascades is determined by direct and indirect interactions between kinases and their substrates. While the impact…”
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Unmasking Determinants of Specificity in the Human Kinome by Creixell, Pau, Palmeri, Antonio, Miller, Chad J., Lou, Hua Jane, Santini, Cristina C., Nielsen, Morten, Turk, Benjamin E., Linding, Rune

“…Protein kinases control cellular responses to environmental cues by swift and accurate signal processing. Breakdowns in this high-fidelity capability are a…”
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Military Transportation in State Freight and Defense Community Plans by Miller, Chad R.

“…The US Department of Defense (DoD) makes extensive use of the US multimodal transportation network to move material for operational support, keep facilities…”
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Impact of Infection on Stroke Morbidity and Outcomes by Miller, Chad M., Behrouz, Réza

“…Each year, millions of persons worldwide are disabled by stroke. The burden of stroke is expected to increase as a consequence of growth in our elderly…”
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LI-RADS Treatment Response Algorithm: Performance and Diagnostic Accuracy by Shropshire, Erin L, Chaudhry, Mohammad, Miller, Chad M, Allen, Brian C, Bozdogan, Erol, Cardona, Diana M, King, Lindsay Y, Janas, Gemini L, Do, Richard K, Kim, Charles Y, Ronald, James, Bashir, Mustafa R

“…Background In 2017, the Liver Imaging Reporting and Data System (LI-RADS) included an algorithm for the assessment of hepatocellular carcinoma (HCC) treated…”
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Is LGBT Progress Seen as an Attack on Christians?: Examining Christian/Sexual Orientation Zero-Sum Beliefs by Wilkins, Clara L., Wellman, Joseph D., Toosi, Negin R., Miller, Chad A., Lisnek, Jaclyn A., Martin, Lerone A.

“…As social policies have changed to grant more rights to lesbian, gay, bisexual, and transgender (LGBT) individuals, some Christians in the United States have…”
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Impact of biophilic design on college student perception of mental health and environmental benefits: A dose-response study by Li, Kaigang, Perrault, Ashley, DeYoung, Wendy A., Cameron, Emma, Miller, Chad T., O'Connor, Alison S., Gu, Mengmeng, Braun, Barry

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Tuning the Properties of Polymer Bulk Heterojunction Solar Cells by Adjusting Fullerene Size to Control Intercalation by Cates, Nichole C, Gysel, Roman, Beiley, Zach, Miller, Chad E, Toney, Michael F, Heeney, Martin, McCulloch, Iain, McGehee, Michael D

“…We demonstrate that intercalation of fullerene derivatives between the side chains of conjugated polymers can be controlled by adjusting the fullerene size and…”
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White by Another Name? Can Anti-Christian Bias Claims Serve as a Racial Dog Whistle? by Al-Kire, Rosemary L., Miller, Chad A., Pasek, Michael H., Perry, Samuel L., Wilkins, Clara L.

“…Four preregistered experiments (N = 4,307) explored whether anti-Christian bias claims can discreetly signal White allyship among Christian American adults. In…”
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Computational design of a synthetic PD-1 agonist by Bryan, Cassie M., Rocklin, Gabriel J., Bick, Matthew J., Ford, Alex, Majri-Morrison, Sonia, Kroll, Ashley V., Miller, Chad J., Carter, Lauren, Goreshnik, Inna, Kang, Alex, DiMaio, Frank, Tarbell, Kristin V., Baker, David

“…Programmed cell death protein-1 (PD-1) expressed on activated T cells inhibits T cell function and proliferation to prevent an excessive immune response, and…”
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Safety and tolerability of transition from inhaled treprostinil to oral selexipag in pulmonary arterial hypertension: Results from the TRANSIT-1 study by Frost, Adaani, Janmohamed, Munir, Fritz, Jason S., McConnell, John W., Poch, David, Fortin, Terry Ann, Miller, Chad E., Chin, Kelly M., Fisher, Micah, Eggert, Michael, McEvoy, Colleen, Benza, Raymond L., Farber, Harrison W., Kim, Nick H., Pfister, Thomas, Shiraga, Yoko, McLaughlin, Vallerie

“…A long-term trial showed that the oral prostacyclin (PGl2) receptor (IP) agonist, selexipag, delayed disease progression in patients with pulmonary arterial…”
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CT in the Emergency Department: A Real-Time Study of Changes in Physician Decision Making by Pandharipande, Pari V, Reisner, Andrew T, Binder, William D, Zaheer, Atif, Gunn, Martin L, Linnau, Ken F, Miller, Chad M, Avery, Laura L, Herring, Maurice S, Tramontano, Angela C, Dowling, Emily C, Abujudeh, Hani H, Eisenberg, Jonathan D, Halpern, Elkan F, Donelan, Karen, Gazelle, G Scott

“…To determine how physicians' diagnoses, diagnostic uncertainty, and management decisions are affected by the results of computed tomography (CT) in emergency…”
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Automated selection of abdominal MRI series using a DICOM metadata classifier and selective use of a pixel-based classifier by Miller, Chad M., Zhu, Zhe, Mazurowski, Maciej A., Bashir, Mustafa R., Wiggins, Walter F.

“…Accurate, automated MRI series identification is important for many applications, including display (“hanging”) protocols, machine learning, and radiomics. The…”
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Consensus summary statement of the International Multidisciplinary Consensus Conference on Multimodality Monitoring in Neurocritical Care by Le Roux, Peter, Menon, David K, Citerio, Giuseppe, Vespa, Paul, Bader, Mary Kay, Brophy, Gretchen M, Diringer, Michael N

“…Neurocritical care depends, in part, on careful patient monitoring but as yet there are little data on what processes are the most important to monitor, how…”
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