Search Results - "MILLAY, Meredith"
-
1
Sonic Hedgehog–Modified Human CD34+ Cells Preserve Cardiac Function After Acute Myocardial Infarction
Published in Circulation research (20-07-2012)“…RATIONALE:Ischemic cardiovascular disease represents one of the largest epidemics currently facing the aging population. Current literature has illustrated the…”
Get full text
Journal Article -
2
A Randomized, Controlled Pilot Study of Autologous CD34+ Cell Therapy for Critical Limb Ischemia
Published in Circulation. Cardiovascular interventions (01-12-2012)“…Critical limb ischemia portends a risk of major amputation of 25% to 35% within 1 year of diagnosis. Preclinical studies provide evidence that intramuscular…”
Get full text
Journal Article -
3
Generation of conditional alleles for Foxc1 and Foxc2 in mice
Published in Genesis (New York, N.Y. : 2000) (01-10-2012)“…The Forkhead box transcription factors, Foxc1 and Foxc2, are crucial for development of the eye, cardiovascular network, and other physiological systems, but…”
Get full text
Journal Article -
4
Enhanced potency of cell-based therapy for ischemic tissue repair using an injectable bioactive epitope presenting nanofiber support matrix
Published in Journal of molecular and cellular cardiology (01-09-2014)“…Abstract The translation of cell-based therapies for ischemic tissue repair remains limited by several factors, including poor cell survival and limited target…”
Get full text
Journal Article -
5
Exosomes From Human CD34+ Stem Cells Mediate Their Proangiogenic Paracrine Activity
Published in Circulation research (16-09-2011)“…RATIONALE:Transplantation of human CD34 stem cells to ischemic tissues has been associated with reduced angina, improved exercise time, and reduced amputation…”
Get full text
Journal Article -
6
Foxc1 and Foxc2 deletion causes abnormal lymphangiogenesis and correlates with ERK hyperactivation
Published in The Journal of clinical investigation (01-07-2016)“…The lymphatic vasculature is essential for maintaining interstitial fluid homeostasis, and dysfunctional lymphangiogenesis contributes to various pathological…”
Get full text
Journal Article -
7
CXCR4 Antagonist AMD3100 Accelerates Impaired Wound Healing in Diabetic Mice
Published in Journal of investigative dermatology (01-03-2012)“…The antagonism of CXC-chemokine receptor 4 (CXCR4) with AMD3100 improves cardiac performance after myocardial infarction by augmenting the recruitment of…”
Get full text
Journal Article -
8
The Hedgehog Transcription Factor Gli3 Modulates Angiogenesis
Published in Circulation research (09-10-2009)“…RATIONALE:The Gli transcription factors are mediators of Hedgehog (Hh) signaling and have been shown to play critical roles during embryogenesis. Previously,…”
Get full text
Journal Article -
9
Abstract 18384: Hypoxia-Induced FOXC2 Expression in Human Endothelial Cells is Dependent on the MEK and PI3K Pathways
Published in Circulation (New York, N.Y.) (26-11-2013)“…Abstract only FoxC2, a member of the Forkhead box (Fox) transcription factor family, is critical for vascular formation during embryonic development and tumor…”
Get full text
Journal Article -
10
Abstract P019: Exosomes from Human CD34+ Cells: Critical Mediators of Proangiogenic Paracrine Effect of EPCs
Published in Circulation research (09-12-2011)“…Abstract only Local transplantation of human CD34+ hematopoietic stem cells has been shown to promote neovascularization in pre-clinical studies in models of…”
Get full text
Journal Article -
11
Sonic Hedgehog Modified Human CD34+ Cells Preserve Cardiac Function Following Acute Myocardial Infarction
Published in Circulation research (10-05-2012)Get full text
Journal Article -
12
Exosomes from Human CD34+ Stem Cells Mediate their Pro-angiogenic Paracrine Activity
Published in Circulation research (11-08-2011)Get full text
Journal Article -
13
Abstract 5445: Gli2 and Gli3 Are Over-expressed in the Ischemic Tissue and Participate in Ischemia-induced Angiogenesis and Myogenesis
Published in Circulation (New York, N.Y.) (28-10-2008)“…Abstract only Gli transcription factors are mediators of hedgehog signaling and have been shown to be critical in several steps during development. In…”
Get full text
Journal Article -
14
Abstract 5278: The Sonic Hedgehog Transcription Factor Gli3 Modulates Ischemia-induced Angiogenesis
Published in Circulation (New York, N.Y.) (28-10-2008)“…Abstract only Gli transcription factors are mediators of hedgehog signaling and have been shown to be critical in several steps during development. We have…”
Get full text
Journal Article