Search Results - "MILHAS, D"

Microenvironment mesenchymal cells protect ovarian cancer cell lines from apoptosis by inhibiting XIAP inactivation by Castells, M, Milhas, D, Gandy, C, Thibault, B, Rafii, A, Delord, J-P, Couderc, B

“…Epithelial ovarian carcinoma is characterized by high frequency of recurrence (70% of patients) and carboplatin resistance acquisition. Carcinoma-associated…”
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Caspase-mediated inhibition of sphingomyelin synthesis is involved in FasL-triggered cell death by Lafont, E, Milhas, D, Carpentier, S, Garcia, V, Jin, Z-X, Umehara, H, Okazaki, T, Schulze-Osthoff, K, Levade, T, Benoist, H, Ségui, B

“…Ceramide can be converted into sphingomyelin by sphingomyelin synthases (SMS) 1 and 2. In this study, we show that in human leukemia Jurkat cells, which…”
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Caspase-dependent and -independent cell death of Jurkat human leukemia cells induced by novel synthetic ceramide analogs by GRANOT, T, MILHAS, D, CARPENTIER, S, DAGAN, A, SEGUI, B, GATT, S, LEVADE, T

“…Ceramide metabolism has emerged as a potential target for anticancer therapy. Here, the potential usefulness of two novel synthetic ceramide analogs as…”
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The adipose tissue that surrounds the prostate gland exhibits traits of hypoxic state that could contribute to its role in prostate cancer progression by Roumiguie, M., Manceau, C., Estève, D., Belles, C., Gilleron, J., Bouloumié, A., Malavaud, B., Milhas, D., Muller, C.

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The tricyclodecan-9-yl-xanthogenate D609 triggers ceramide increase and enhances FasL-induced caspase-dependent and -independent cell death in T lymphocytes by Milhas, Delphine, Andrieu-Abadie, Nathalie, Levade, Thierry, Benoist, Hervé, Ségui, Bruno

“…D609 is known to modulate death receptor-induced ceramide generation and cell death. We show that in Jurkat cells, non-toxic D609 concentrations inhibit…”
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Caspase-10 Triggers Bid Cleavage and Caspase Cascade Activation in FasL-induced Apoptosis by Milhas, Delphine, Cuvillier, Olivier, Therville, Nicole, Clavé, Patricia, Thomsen, Mogens, Levade, Thierry, Benoist, Hervé, Ségui, Bruno

“…In contrast to caspase-8, controversy exists as to the ability of caspase-10 to mediate apoptosis in response to FasL. Herein, we have shown activation of…”
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The adipose tissue that surrounds the prostate gland exhibits traits of hypoxic state that could contribute to its role in prostate cancer progression by Roumiguie, M., Toulet, A., Estève, D., Belles, C., Gilleron, J., Chaoui, K., Ducoux-Petit, M., Burlet-Schiltz, O., Bouloumié, A., Malavaud, B., Milhas, D., Muller, C.

“…Introduction & Objectives: The prostate gland is surrounded by periprostatic adipose tissue (PPAT), whose role in prostate cancer (PCa)progression has been…”
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O05 - The adipose tissue that surrounds the prostate gland exhibits traits of hypoxic state that could contribute to its role in prostate cancer progression by Roumiguie, M., Toulet, A., Estève, D., Belles, C., Gilleron, J., Chaoui, K., Ducoux-Petit, M., Burlet-Schiltz, O., Bouloumié, A., Malavaud, B., Milhas, D., Muller, C.

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