Search Results - "MILANI, DANIELA"
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Sex/Gender-Specific Imbalance in CVD: Could Physical Activity Help to Improve Clinical Outcome Targeting CVD Molecular Mechanisms in Women?
Published in International journal of molecular sciences (21-02-2020)“…In the last two decades, new insights have been gained regarding sex/gender-related differences in cardiovascular disease (CVD). CVD represents the leading…”
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Purinergic Signaling in Controlling Macrophage and T Cell Functions During Atherosclerosis Development
Published in Frontiers in immunology (16-02-2021)“…Atherosclerosis is a hardening and narrowing of arteries causing a reduction of blood flow. It is a leading cause of death in industrialized countries as it…”
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p53/NF-kB Balance in SARS-CoV-2 Infection: From OMICs, Genomics and Pharmacogenomics Insights to Tailored Therapeutic Perspectives (COVIDomics)
Published in Frontiers in pharmacology (27-05-2022)“…SARS-CoV-2 infection affects different organs and tissues, including the upper and lower airways, the lung, the gut, the olfactory system and the eye, which…”
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Classical and Innovative Evidence for Therapeutic Strategies in Retinal Dysfunctions
Published in International journal of molecular sciences (01-02-2024)“…The human retina is a complex anatomical structure that has no regenerative capacity. The pathogenesis of most retinopathies can be attributed to inflammation,…”
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miRNAs as Influencers of Cell-Cell Communication in Tumor Microenvironment
Published in Cells (Basel, Switzerland) (15-01-2020)“…microRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the posttranscriptional level, inducing the degradation of the target mRNA or…”
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Fluorescent Water-Soluble Polycationic Chitosan Polymers as Markers for Biological 3D Imaging
Published in Chemical & biomedical imaging (28-10-2024)“…Over the last decades, various tissue-clearing techniques have broken the ground for the optical imaging of whole organs and whole-organisms, providing…”
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F13A1 Gene Variant (V34L) and Residual Circulating FXIIIA Levels Predict Short- and Long-Term Mortality in Acute Myocardial Infarction after Coronary Angioplasty
Published in International journal of molecular sciences (14-09-2018)“…Factor XIIIA (FXIIIA) levels are independent predictors of early prognosis after acute myocardial infarction (AMI) and the Valine-to-Leucine (V34L) single…”
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Overcoming of Microenvironment Protection on Primary Chronic Lymphocytic Leukemia Cells after Treatment with BTK and MDM2 Pharmacological Inhibitors
Published in Current oncology (Toronto) (01-07-2021)“…In B-chronic lymphocytic leukemia (B-CLL), the interaction between leukemic cells and the microenvironment promotes tumor cell survival. The Bruton's tyrosine…”
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TRAIL promotes the survival and proliferation of primary human vascular endothelial cells by activating the Akt and ERK pathways
Published in Circulation (New York, N.Y.) (06-05-2003)“…TRAIL protein is expressed in the medial smooth cell layer of aorta and pulmonary artery, whereas endothelial cells express all TRAIL receptors (TRAIL-Rs). The…”
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Two-dimensional gel electrophoresis analysis of the leiomyoma interstitial fluid reveals altered protein expression with a possible involvement in pathogenesis
Published in Oncology reports (01-05-2015)“…Uterine leiomyoma is the most common smooth benign neoplasm. In the present study, we analyzed the global interstitial fluid (IF) profile of leiomyoma vs…”
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Reversal of the glycolytic phenotype of primary effusion lymphoma cells by combined targeting of cellular metabolism and PI3K/Akt/ mTOR signaling
Published in Oncotarget (02-02-2016)“…PEL is a B-cell non-Hodgkin lymphoma, occurring predominantly as a lymphomatous effusion in body cavities, characterized by aggressive clinical course, with no…”
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Crosstalk Between Adipokines and Paraoxonase 1: A New Potential Axis Linking Oxidative Stress and Inflammation
Published in Antioxidants (06-08-2019)“…Paraoxonase 1 (PON1) is a high-density lipoprotein (HDL)-associated protein that endows its carrier with (lipo-)lactonase-dependent antioxidative features. Low…”
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TRAIL as biomarker and potential therapeutic tool for cardiovascular diseases
Published in Current drug targets (01-08-2012)“…This review focuses on TNF-related apoptosis-inducing ligand (TRAIL), also called Apo2 ligand, a protein belonging to the TNF superfamily. TRAIL can be found…”
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Validation of the Informal Caregiver Burden Assessment Questionnaire for Brazil – short version
Published in Revista Brasileira de Enfermagem (01-01-2022)“…ABSTRACT Objectives: to cross-culturally adapt the short version of the Informal Caregiver Burden Assessment Questionnaire to the Brazilian culture and test…”
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Kinetic Profiles of Inflammatory Mediators in the Conjunctival Sac Fluid of Patients upon Photorefractive Keratectomy
Published in Mediators of Inflammation (01-01-2015)“…Photorefractive keratectomy (PRK) represents a therapeutic option to remodel corneal stroma and to compensate refractive errors, which involves inflammatory…”
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Upregulation of SOCS-1 by Nutlin-3 in acute myeloid leukemia cells but not in primary normal cells
Published in Clinics (São Paulo, Brazil) (01-01-2014)“…It has been shown that SOCS-1 plays an important role in the proper control of cytokine/growth factor responses and acts as a tumor suppressor in acute myeloid…”
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Literacia em saúde: tradução e validação de instrumento para pesquisa em promoção da saúde no Brasil
Published in Cadernos de saúde pública (2017)“…Resumo: O objetivo do trabalho foi traduzir, adaptar culturalmente e testar o desempenho psicométrico de um questionário para avaliar a literacia em saúde…”
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The MDM-2 Antagonist Nutlin-3 Promotes the Maturation of Acute Myeloid Leukemic Blasts
Published in Neoplasia (New York, N.Y.) (01-10-2007)“…The small-molecule inhibitor of murine double minute (MDM-2), Nutlin-3, induced variable apoptosis in primary acute myeloid leukemia (AML) blasts, promoted…”
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Variability and Reliability of single Serum IGF-I Measurements: Impact on Determining Predictability of Risk Ratios in Disease Development
Published in The journal of clinical endocrinology and metabolism (01-05-2004)“…In recent years, a number of investigators have studied the relationship between IGF-I and risk of developing cancer, diabetes or cardiovascular disease. Upper…”
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Tumor necrosis factor–related apoptosis-inducing ligand induces monocytic maturation of leukemic and normal myeloid precursors through a caspase-dependent pathway
Published in Blood (01-10-2002)“…Treatment of the human HL-60 cell line with tumor necrosis factor (TNF)–related apoptosis-inducing ligand (TRAIL) resulted in rapid (6-24 hours) cytotoxicity…”
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