Search Results - "MIKULA, M."

Photoprotective efficacy and photostability of fifteen sunscreen products having the same label SPF subjected to natural sunlight by Hojerová, J., Medovcíková, A., Mikula, M.

“…The first objective of this study is to show how different can be photoprotection by sunscreens with an identical SPF given on the packaging, when subjected to…”
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Segmental isotopic labeling of a single‐domain globular protein without any refolding step by an asparaginyl endopeptidase by Mikula, Kornelia M., Tascón, Igor, Tommila, Jenni J., Iwaï, Hideo

“…Asparaginyl endopeptidases (AEPs) catalyze head‐to‐tail backbone cyclization of naturally occurring cyclic peptides such as cyclotides, and have become an…”
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The transcription factor ZEB1 ( EF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity by AIGNER, K, DAMPIER, B, SOMMERGRUBER, W, SCHWEIFER, N, WERNITZNIG, A, BEUG, H, FOISNER, R, EGER, A, DESCOVICH, L, MIKULA, M, SULTAN, A, SCHREIBER, M, MIKULITS, W, BRABLETZ, T, STRAND, D, OBRIST, P

“…Epithelial to mesenchymal transition (EMT) is implicated in the progression of primary tumours towards metastasis and is likely caused by a pathological…”
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Segmental isotopic labeling by asparaginyl endopeptidase-mediated protein ligation by Mikula, Kornelia M., Krumwiede, Luisa, Plückthun, Andreas, Iwaï, Hideo

“…Segmental isotopic labeling can facilitate NMR studies of large proteins, multi-domain proteins, and proteins with repetitive sequences by alleviating NMR…”
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Fast highly-sensitive room-temperature semiconductor gas sensor based on the nanoscale Pt–TiO2–Pt sandwich by Plecenik, T., Moško, M., Haidry, A.A., Ďurina, P., Truchlý, M., Grančič, B., Gregor, M., Roch, T., Satrapinskyy, L., Mošková, A., Mikula, M., Kúš, P., Plecenik, A.

“…•Hydrogen gas sensor based on the nanoscale Pt–TiO2–Pt sandwich is presented.•The sensor exhibits high sensitivity and fast reaction time at room…”
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DNA methylation status is more reliable than gene expression at detecting cancer in prostate biopsy by Paziewska, A, Dabrowska, M, Goryca, K, Antoniewicz, A, Dobruch, J, Mikula, M, Jarosz, D, Zapala, L, Borowka, A, Ostrowski, J

“…Background: We analysed critically the potential usefulness of RNA- and DNA-based biomarkers in supporting conventional histological diagnostic tests for…”
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Biosynthesis of the Bis-Prenylated Alkaloids Muscoride A and B by Mattila, Antti, Andsten, Rose-Marie, Jumppanen, Mikael, Assante, Michele, Jokela, Jouni, Wahlsten, Matti, Mikula, Kornelia M, Sigindere, Cihad, Kwak, Daniel H, Gugger, Muriel, Koskela, Harri, Sivonen, Kaarina, Liu, Xinyu, Yli-Kauhaluoma, Jari, Iwaï, Hideo, Fewer, David P

“…Prenylation is a common step in the biosynthesis of many natural products and plays an important role in increasing their structural diversity and enhancing…”
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Effect of reflected Ar neutrals on tantalum diboride coatings prepared by direct current magnetron sputtering by Viskupová, K., Grančič, B., Roch, T., Satrapinskyy, L., Truchlý, M., Mikula, M., Šroba, V., Ďurina, P., Kúš, P.

“…The magnetron sputtered tantalum diboride (TaBy) coatings from stoichiometric TaB2 target are often reported to be deposited in broad B/Ta interval with…”
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Nanohardness and tribological properties of nc-TiB2 coatings by Lofaj, F., Moskalewicz, T., Cempura, G., Mikula, M., Dusza, J., Czyrska-Filemonowicz, A.

“…The work is devoted to the investigation of nanohardness and tribological properties in TiB2 coatings deposited on austenitic steel substrates using an…”
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Yersinia infection tools-characterization of structure and function of adhesins by Mikula, Kornelia M, Kolodziejczyk, Robert, Goldman, Adrian

“…Among the seventeen species of the Gram-negative genus Yersinia, three have been shown to be virulent and pathogenic to humans and animals-Y. enterocolitica,…”
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ILEI requires oncogenic Ras for the epithelial to mesenchymal transition of hepatocytes and liver carcinoma progression by Lahsnig, C, Mikula, M, Petz, M, Zulehner, G, Schneller, D, van Zijl, F, Huber, H, Csiszar, A, Beug, H, Mikulits, W

“…In human hepatocellular carcinoma (HCC), epithelial to mesenchymal transition (EMT) correlates with aggressiveness of tumors and poor survival. We employed a…”
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Crystal structure of a tripartite complex between C3dg, C-terminal domains of factor H and OspE of Borrelia burgdorferi by Kolodziejczyk, Robert, Mikula, Kornelia M, Kotila, Tommi, Postis, Vincent L G, Jokiranta, T Sakari, Goldman, Adrian, Meri, Taru

“…Complement is an important part of innate immunity. The alternative pathway of complement is activated when the main opsonin, C3b coats non-protected surfaces…”
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PDGF essentially links TGF-β signaling to nuclear β-catenin accumulation in hepatocellular carcinoma progression by FISCHER, A. N. M, FUCHS, E, MIKULA, M, HUBER, H, BEUG, H, MIKULITS, W

“…The cooperation of Ras - extracellular signal-regulated kinase/mitogen-activated protein kinase and transforming growth factor (TGF)-beta signaling provokes an…”
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The Convergence of the Hedgehog/Intein Fold in Different Protein Splicing Mechanisms by Beyer, Hannes M, Virtanen, Salla I, Aranko, A Sesilja, Mikula, Kornelia M, Lountos, George T, Wlodawer, Alexander, Ollila, O H Samuli, Iwaï, Hideo

“…Protein splicing catalyzed by inteins utilizes many different combinations of amino-acid types at active sites. Inteins have been classified into three classes…”
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Genome-wide co-localization of active EGFR and downstream ERK pathway kinases mirrors mitogen-inducible RNA polymerase 2 genomic occupancy by Mikula, M, Skrzypczak, M, Goryca, K, Paczkowska, K, Ledwon, J K, Statkiewicz, M, Kulecka, M, Grzelak, M, Dabrowska, M, Kuklinska, U, Karczmarski, J, Rumienczyk, I, Jastrzebski, K, Miaczynska, M, Ginalski, K, Bomsztyk, K, Ostrowski, J

“…Genome-wide mechanisms that coordinate expression of subsets of functionally related genes are largely unknown. Recent studies show that receptor tyrosine…”
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FT IR spectroscopy of silicon oxide layers prepared with perchloric acid by Kopani, M., Mikula, M., Takahashi, M., Rusnák, J., Pinčík, E.

“…► Formation of stoichiometric SiO2 layer with lowest density after chlorine oxidation ► KCN/HCN passivation contributes to formation of SiN, SiO and SiOH bonds…”
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A crucial function of PDGF in TGF-β-mediated cancer progression of hepatocytes by GOTZMANN, J, FISCHER, A. N. M, MIKULITS, W, ZOJER, M, MIKULA, M, PROELL, V, HUBER, H, JECHLINGER, M, WAERNER, T, WEITH, A, BEUG, H

“…Polarized hepatocytes expressing hyperactive Ha-Ras adopt an invasive and metastatic phenotype in cooperation with transforming growth factor (TGF)-beta. This…”
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Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene by Mikula, Mario, Schreiber, Martin, Husak, Zvenislava, Kucerova, Lucia, Rüth, Jochen, Wieser, Rotraud, Zatloukal, Kurt, Beug, Hartmut, Wagner, Erwin F., Baccarini, Manuela

“…The Raf kinases play a key role in relaying signals elicited by mitogens or oncogenes. Here, we report that c‐raf‐1−/− embryos are growth retarded and die at…”
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FT IR spectroscopy of nitric acid oxidation of silicon with hafnium oxide very thin layer by Kopani, M., Mikula, M., Pinčík, E., Kobayashi, H., Takahashi, M.

“…•Low temperature oxidation method with very thin hafnium oxide for improve electrical characteristics was used.•We investigated the influence of…”
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Stoichiometry, structure and mechanical properties of co-sputtered Ti1-xTaxB2±Δ coatings by Grančič, B., Pleva, M., Mikula, M., Čaplovičová, M., Satrapinskyy, L., Roch, T., Truchlý, M., Sahul, M., Gregor, M., Švec, P., Zahoran, M., Kúš, P.

“…Magnetron co-sputtering from TiB2 and TaB2 stoichiometric targets is used to prepare AlB2-prototype ternary Ti1-xTaxB2±Δ solid solution, with x in the range…”
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