Search Results - "MIKKAT, Stefan"
-
1
Ethanol, glycogen and glucosylglycerol represent competing carbon pools in ethanol-producing cells of Synechocystis sp. PCC 6803 under high-salt conditions
Published in Microbiology (Society for General Microbiology) (01-03-2017)“…Cyanobacteria are photoautotrophic micro-organisms, which are increasingly being used as microbial cell factories to produce, for example, ethanol directly…”
Get full text
Journal Article -
2
The cyanobacterial hepatotoxin microcystin binds to proteins and increases the fitness of microcystis under oxidative stress conditions
Published in PloS one (18-03-2011)“…Microcystins are cyanobacterial toxins that represent a serious threat to drinking water and recreational lakes worldwide. Here, we show that microcystin…”
Get full text
Journal Article -
3
Integrative analysis of the salt stress response in cyanobacteria
Published in Biology direct (14-12-2021)“…Microorganisms evolved specific acclimation strategies to thrive in environments of high or fluctuating salinities. Here, salt acclimation in the model…”
Get full text
Journal Article -
4
Lysine Phoshoglycerylation Is Widespread in Bacteria and Overlaps with Acylation
Published in Microorganisms (Basel) (30-07-2024)“…Phosphoglycerylation is a non-enzymatic protein modification in which a phosphoglyceryl moiety is covalently bound to the ε-amino group of lysine. It is…”
Get full text
Journal Article -
5
Dynamic Protein Phosphorylation in Streptococcus pyogenes during Growth, Stationary Phase, and Starvation
Published in Microorganisms (Basel) (20-03-2024)“…Phosphorylation of proteins at serine, threonine, and tyrosine residues plays an important role in physiological processes of bacteria, such as cell cycle,…”
Get full text
Journal Article -
6
A 2D gel electrophoresis-based snapshot of the phosphoproteome in the cyanobacterium Synechocystis sp. strain PCC 6803
Published in Microbiology (Society for General Microbiology) (01-02-2014)“…Cyanobacteria are photoautotrophic prokaryotes that occur in highly variable environments. Protein phosphorylation is one of the most widespread means to…”
Get full text
Journal Article -
7
Immunogenicity and contraceptive efficacy of plant-produced putative mouse-specific contraceptive peptides
Published in Frontiers in plant science (28-06-2023)“…Rodent population control through contraception requires species-specific oral contraceptive vaccines. Therefore, in this study, we produced putative…”
Get full text
Journal Article -
8
Periodontal pathogens alter the synovial proteome. Periodontal pathogens do not exacerbate macroscopic arthritis but alter the synovial proteome in mice
Published in PloS one (31-12-2020)“…Rheumatoid arthritis (RA) and periodontitis (PD) are chronic inflammatory diseases that appear to occur in tandem. However, the mutual impact PD exerts on RA…”
Get full text
Journal Article -
9
Synthetic mRNA delivered to human cells leads to expression of Cpl-1 bacteriophage-endolysin with activity against Streptococcus pneumoniae
Published in Molecular therapy. Nucleic acids (12-03-2024)“…Endolysins are bacteriophage-encoded hydrolases that show high antibacterial activity and a narrow substrate spectrum. We hypothesize that an mRNA-based…”
Get full text
Journal Article -
10
Cytosine N4-Methylation via M.Ssp6803II Is Involved in the Regulation of Transcription, Fine- Tuning of DNA Replication and DNA Repair in the Cyanobacterium Synechocystis sp. PCC 6803
Published in Frontiers in microbiology (05-06-2019)“…DNA methylation plays a crucial role for gene regulation among eukaryotes, but its regulatory function is less documented in bacteria. In the cyanobacterium…”
Get full text
Journal Article -
11
The Regulatory Small RNA MarS Supports Virulence of Streptococcus pyogenes
Published in Scientific reports (25-09-2017)“…Small regulatory RNAs (sRNAs) play a role in the control of bacterial virulence gene expression. In this study, we investigated an sRNA that was identified in…”
Get full text
Journal Article -
12
The contact system proteases play disparate roles in streptococcal sepsis
Published in Haematologica (Roma) (01-05-2020)“…Sepsis causes an activation of the human contact system, an inflammatory response mechanism against foreign surfaces, proteins and pathogens. The serine…”
Get full text
Journal Article -
13
Immune Evasion of the Human Pathogen Pseudomonas aeruginosa: Elongation Factor Tuf Is a Factor H and Plasminogen Binding Protein
Published in Journal of Immunology (01-09-2007)“…Pseudomonas aeruginosa is an opportunistic human pathogen that can cause a wide range of clinical symptoms and infections that are frequent in…”
Get full text
Journal Article -
14
Memory-Enhancing Effects of Origanum majorana Essential Oil in an Alzheimer’s Amyloid beta1-42 Rat Model: A Molecular and Behavioral Study
Published in Antioxidants (01-10-2020)“…Origanum L. (Lamiaceae) is an important genus of medicinal and aromatic plants used in traditional medicine since ancient times as culinary herbs and remedies…”
Get full text
Journal Article -
15
Deletion of the L-Lactate Dehydrogenase Gene ldh in Streptococcus pyogenes Leads to a Loss of SpeB Activity and a Hypovirulent Phenotype
Published in Frontiers in microbiology (21-09-2017)“…uses lactic acid fermentation for the generation of ATP. Here, we analyzed the impact of a deletion of the L-lactate dehydrogenase gene on the virulence of…”
Get full text
Journal Article -
16
Kininogen supports inflammation and bacterial spreading during Streptococccus Pyogenes Sepsis
Published in EBioMedicine (01-08-2020)“…High-molecular-weight kininogen is a cofactor of the human contact system, an inflammatory response mechanism that is activated during sepsis. It has been…”
Get full text
Journal Article -
17
Membrane Protein Identification in Rodent Brain Tissue Samples and Acute Brain Slices
Published in Cells (Basel, Switzerland) (08-05-2019)“…Acute brain slices are a sample format for electrophysiology, disease modeling, and organotypic cultures. Proteome analyses based on mass spectrometric…”
Get full text
Journal Article -
18
An Extracellular Glycoprotein Is Implicated in Cell-Cell Contacts in the Toxic Cyanobacterium Microcystis aeruginosa PCC 7806
Published in Journal of Bacteriology (01-04-2008)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
19
CIN85 Interacting Proteins in B Cells-Specific Role for SHIP-1
Published in Molecular & cellular proteomics (01-10-2011)“…The Cbl-interacting 85-kDa protein (CIN85) plays an important role as a negative regulator of signaling pathways induced by receptor tyrosine kinases. By…”
Get full text
Journal Article -
20
2-DE proteome analysis of a proliferating and differentiating human neuronal stem cell line (ReNcell VM)
Published in Proteomics (Weinheim) (01-03-2006)“…The proteome of a proliferating human stem cell line was analyzed and then utilized to detect stem cell differentiation‐associated changes in the protein…”
Get full text
Journal Article