Search Results - "MIELE, E."

Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia by Kumar, V, Palermo, R, Talora, C, Campese, A F, Checquolo, S, Bellavia, D, Tottone, L, Testa, G, Miele, E, Indraccolo, S, Amadori, A, Ferretti, E, Gulino, A, Vacca, A, Screpanti, I

“…Notch signaling deregulation is linked to the onset of several tumors including T-cell acute lymphoblastic leukemia (T-ALL). Deregulated microRNA (miRNA)…”
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Thioredoxin reductase and its inhibitors by Saccoccia, Fulvio, Angelucci, Francesco, Boumis, Giovanna, Carotti, Daniela, Desiato, Gianni, Miele, Adriana E, Bellelli, Andrea

“…Thioredoxin plays a crucial role in a wide number of physiological processes, which span from reduction of nucleotides to deoxyriboucleotides to the…”
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Noncanonical GLI1 signaling promotes stemness features and in vivo growth in lung adenocarcinoma by Po, A, Silvano, M, Miele, E, Capalbo, C, Eramo, A, Salvati, V, Todaro, M, Besharat, Z M, Catanzaro, G, Cucchi, D, Coni, S, Di Marcotullio, L, Canettieri, G, Vacca, A, Stassi, G, De Smaele, E, Tartaglia, M, Screpanti, I, De Maria, R, Ferretti, E

“…Aberrant Hedgehog/GLI signaling has been implicated in a diverse spectrum of human cancers, but its role in lung adenocarcinoma (LAC) is still under debate. We…”
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A Systematic Review and Meta-analysis of Paediatric Inflammatory Bowel Disease Incidence and Prevalence Across Europe by Roberts, S E, Thorne, K, Thapar, N, Broekaert, I, Benninga, M A, Dolinsek, J, Mas, E, Miele, E, Orel, R, Pienar, C, Ribes-Koninckx, C, Thomson, M, Tzivinikos, C, Morrison-Rees, S, John, A, Williams, J G

“…Abstract Background and Aims Inflammatory bowel disease [IBD] is often one of the most devastating and debilitating chronic gastrointestinal disorders in…”
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An ESPGHAN Position Paper on the Use of Low‐FODMAP Diet in Pediatric Gastroenterology by Thomassen, R.A., Luque, V., Assa, A., Borrelli, O., Broekaert, I., Dolinsek, J., Martin‐de‐Carpi, J., Mas, E., Miele, E., Norsa, L., Ribes‐Koninckx, C., Saccomani, M. Deganello, Thomson, M., Tzivinikos, C., Verduci, E., Bronsky, J., Haiden, N., Köglmeier, J., Koning, B., Benninga, M.A.

“…Excluding oligo‐, di‐, monosaccharides and polyols (FODMAPs) from the diet is increasingly being used to treat children with gastrointestinal complaints. The…”
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Delivery of Brain-Derived Neurotrophic Factor by 3D Biocompatible Polymeric Scaffolds for Neural Tissue Engineering and Neuronal Regeneration by Limongi, T., Rocchi, A., Cesca, F., Tan, H., Miele, E., Giugni, A., Orlando, M., Perrone Donnorso, M., Perozziello, G., Benfenati, Fabio, Di Fabrizio, Enzo

“…Biopolymers are increasingly employed for neuroscience applications as scaffolds to drive and promote neural regrowth, thanks to their ability to mediate the…”
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Mapping the Catalytic Cycle of Schistosoma mansoni Thioredoxin Glutathione Reductase by X-ray Crystallography by Angelucci, Francesco, Dimastrogiovanni, Daniela, Boumis, Giovanna, Brunori, Maurizio, Miele, Adriana E., Saccoccia, Fulvio, Bellelli, Andrea

“…Schistosomiasis is the second most widespread human parasitic disease. It is principally treated with one drug, praziquantel, that is administered to 100…”
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The miR‐139‐5p regulates proliferation of supratentorial paediatric low‐grade gliomas by targeting the PI3K/AKT/mTORC1 signalling by Catanzaro, G., Besharat, Z. M., Miele, E., Chiacchiarini, M., Po, A., Carai, A., Marras, C. E., Antonelli, M., Badiali, M., Raso, A., Mascelli, S., Schrimpf, D., Stichel, D., Tartaglia, M., Capper, D., Deimling, A., Giangaspero, F., Mastronuzzi, A., Locatelli, F., Ferretti, E.

“…Aims Paediatric low‐grade gliomas (pLGGs) are a heterogeneous group of brain tumours associated with a high overall survival: however, they are prone to recur…”
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Efficacy of a standardized extract of Matricariae chamomilla L., Melissa officinalis L. and tyndallized Lactobacillus acidophilus (HA122) in infantile colic: An open randomized controlled trial by Martinelli, M., Ummarino, D., Giugliano, F. P., Sciorio, E., Tortora, C., Bruzzese, D., De Giovanni, D., Rutigliano, I., Valenti, S., Romano, C., Campanozzi, A., Miele, E., Staiano, A.

“…Background Infant colic (IC) is a prevalent physiological event of infants, which can disrupt the child's home environment. We aimed to investigate the…”
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Estrogen, neuroinflammation and neuroprotection in Parkinson’s disease: Glia dictates resistance versus vulnerability to neurodegeneration by Morale, M.C., Serra, P.A., L’Episcopo, F., Tirolo, C., Caniglia, S., Testa, N., Gennuso, F., Giaquinta, G., Rocchitta, G., Desole, M.S., Miele, E., Marchetti, B.

“…Post-menopausal estrogen deficiency is recognized to play a pivotal role in the pathogenesis of a number of age-related diseases in women, such as…”
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Proton pump inhibitors as a risk factor for paediatric Clostridium difficile infection by TURCO, R., MARTINELLI, M., MIELE, E., ROSCETTO, E., DEL PEZZO, M., GRECO, L., STAIANO, A.

“…Aliment Pharmacol Ther 31, 754–759 Summary Background  Proton pump inhibitors (PPIs) and H2 receptor antagonists (H2RAs) may play an important role on the…”
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Improvement of body composition and bone mineral density after enteral nutrition in pediatric Crohn disease by Strisciuglio, C., Scarpato, E., Cenni, S., Serra, M.R., Giugliano, F.P., Mainolfi, C.G., Dolce, P., Martinelli, M., Staiano, A., Miele, E.

“…: The relationship between exclusive enteral nutrition (EEN) and bone status is poorly defined in pediatric Crohn disease (CD). : The aim of this study was to…”
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Complex Landscape of Protein Structural Dynamics Unveiled by Nanosecond Laue Crystallography by Bourgeois, Dominique, Vallone, Beatrice, Schotte, Friedrich, Arcovito, Alessandro, Miele, Adriana E., Sciara, Giuliano, Wulff, Michael, Anfinrud, Philip, Brunori, Maurizio

“…Although conformational changes are essential for the function of proteins, little is known about their structural dynamics at atomic level resolution…”
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Pattern of cavities in globins: The case of human hemoglobin by Savino, Carmelinda, Miele, Adriana E., Draghi, Federica, Johnson, Kenneth A., Sciara, Giuliano, Brunori, Maurizio, Vallone, Beatrice

“…Our aim is to shed light on the conservation of potential ligand docking sites that play an important role in ligand dynamics of globins by using the technique…”
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Selenocysteine robustness versus cysteine versatility: a hypothesis on the evolution of the moonlighting behaviour of peroxiredoxins by Saccoccia, Fulvio, Angelucci, Francesco, Boumis, Giovanna, Desiato, Gianni, Miele, Adriana E, Bellelli, Andrea

“…Peroxiredoxins (Prxs) and glutathione peroxidases (Gpxs) provide the majority of peroxides reducing activity in the cytoplasm. Both are peroxidases but…”
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Disease Activity Patterns in the First 5 Years After Diagnosis in Children With Ulcerative Colitis: A Population-Based Study by Aloi, M, Bramuzzo, M, Norsa, L, Arrigo, S, Distante, M, Miele, E, Romano, C, Giobbi, C, Panceri, R, Cucchiara, S, Alvisi, P

“…Abstract Background The aim of this study was to define clusters of activity in a population-based cohort during the first 5 years after diagnosis in children…”
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Faecal calprotectin as reliable non-invasive marker to assess the severity of mucosal inflammation in children with inflammatory bowel disease by Berni Canani, R, Terrin, G, Rapacciuolo, L, Miele, E, Siani, M.C, Puzone, C, Cosenza, L, Staiano, A, Troncone, R

“…Abstract Background An accurate monitoring of mucosal inflammation is important for an effective management of patients with inflammatory bowel disease…”
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A case of cap polyposis masquerading as inflammatory bowel disease by Chiatto, F, Martinelli, M, Strisciuglio, C, Staiano, A, Miele, E

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High resolution anorectal manometry in children with functional constipation with or without fecal incontinence by Turco, R, Alessandrella, A, Pozziello, A, Miele, E, Staiano, A

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Intestinal anti‐tissue transglutaminase antibodies in potential coeliac disease by Tosco, A., Aitoro, R., Auricchio, R., Ponticelli, D., Miele, E., Paparo, F., Greco, L., Troncone, R., Maglio, M.

“…Summary Anti‐tissue transglutaminase 2 (anti‐TG2) antibodies are present in the serum of the great majority of untreated coeliac disease (CD) patients. They…”
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