Search Results - "MIEDEMA, Frank"

Assessing scientists for hiring, promotion, and tenure by Moher, David, Naudet, Florian, Cristea, Ioana A, Miedema, Frank, Ioannidis, John P A, Goodman, Steven N

“…Assessment of researchers is necessary for decisions of hiring, promotion, and tenure. A burgeoning number of scientific leaders believe the current system of…”
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Sparse production but preferential incorporation of recently produced naïve T cells in the human peripheral pool by Vrisekoop, Nienke, den Braber, Ineke, de Boer, Anne Bregje, Ruiter, An F.C, Ackermans, Mariëtte T, van der Crabben, Saskia N, Schrijver, Elise H.R, Spierenburg, Gerrit, Sauerwein, Hans P, Hazenberg, Mette D, de Boer, Rob J, Miedema, Frank, Borghans, José A.M, Tesselaar, Kiki

“…In mice, recent thymic emigrants (RTEs) make up a large part of the naïve T cell pool and have been suggested to be a distinct short-lived pool. In humans,…”
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Toll-like receptor 7-adapter complex modulates interferon-α production in HIV-stimulated plasmacytoid dendritic cells by Patamawenu, Andy A, Wright, Nathaniel E, Shofner, Tulley, Evans, Sean, Manion, Maura M, Doria-Rose, Nicole, Migueles, Stephen A, Mendoza, Daniel, Peterson, Bennett, Wilhelm, Christopher, Rood, Julia, Berkley, Amy, Cogliano, Nancy A, Liang, C Jason, Tesselaar, Kiki, Miedema, Frank, Bess, Jr, Julian, Lifson, Jeffrey, Connors, Mark

“…Plasmacytoid dendritic cells (PDCs) and their production of interferon-alpha (IFN-α) are believed to play an important role in human immunodeficiency virus,…”
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Viral Replication Capacity as a Correlate of HLA B57/B5801-Associated Nonprogressive HIV-1 Infection by Navis, Marjon, Schellens, Ingrid, van Baarle, Debbie, Borghans, Jose, van Swieten, Peter, Miedema, Frank, Kootstra, Neeltje, Schuitemaker, Hanneke

“…HLA B57 and the closely related HLA B5801 are over-represented among HIV-1 infected long-term nonprogressors (LTNPs). It has been suggested that this…”
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Low Immune Activation despite High Levels of Pathogenic Human Immunodeficiency Virus Type 1 Results in Long-Term Asymptomatic Disease by CHOUDHARY, Shailesh K, VRISEKOOP, Nienke, JANSEN, Christine A, OTTO, Sigrid A, SCHUITEMAKER, Hanneke, MIEDEMA, Frank, CAMERMI, David

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Selective Decrease in Circulating Vα24+Vβ11+ NKT Cells During HIV Type 1 Infection by van der Vliet, Hans J. J., von Blomberg, B. Mary E., Hazenberg, Mette D., Nishi, Nobusuke, Otto, Sigrid A., van Benthem, Birgit H., Prins, Maria, Claessen, Frans A., van den Eertwegh, Alfons J. M., Giaccone, Giuseppe, Miedema, Frank, Scheper, Rik J., Pinedo, Herbert M.

“…Abstract CD1d-restricted NKT cells express an invariant TCR and have been demonstrated to play an important regulatory role in a variety of immune responses…”
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Longitudinal Phenotypic Analysis of Human Immunodeficiency Virus Type 1-Specific Cytotoxic T Lymphocytes: Correlation with Disease Progression by Ogg, G S, Kostense, S, Klein, M R, Jurriaans, S, Hamann, D, McMichael, A J, Miedema, F

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Abundance of early functional HIV-specific CD8+ T cells does not predict AIDS-free survival time by Schellens, Ingrid M M, Borghans, José A M, Jansen, Christine A, De Cuyper, Iris M, Geskus, Ronald B, van Baarle, Debbie, Miedema, Frank

“…T-cell immunity is thought to play an important role in controlling HIV infection, and is a main target for HIV vaccine development. HIV-specific central…”
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The HIV RNA setpoint theory revisited by Geskus, Ronald B, Prins, Maria, Hubert, Jean-Baptiste, Miedema, Frank, Berkhout, Ben, Rouzioux, Christine, Delfraissy, Jean-Francois, Meyer, Laurence

“…The evolution of plasma viral load after HIV infection has been described as reaching a setpoint, only to start rising again shortly before AIDS diagnosis. In…”
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Evidence that human CD8+CD45RA+CD27– cells are induced by antigen and evolve through extensive rounds of division by Hamann, Dörte, Kostense, Stefan, Wolthers, Katja C., Otto, Sigrid A., Baars, Paul A., Miedema, Frank, van Lier, René A. W.

“…We recently showed that circulating human CD8+ effector cells have a CD45RA+CD27– membrane phenotype. In itself this phenotype appeared to pose a paradox:…”
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Immunopathology as a result of highly active antiretroviral therapy in HIV-1-infected patients by FOUDRAINE, N. A, HOVENKAMP, E, NOTERMANS, D. W, MEENHORST, P. L, KLEIN, M. R, LANGE, J. M. A, MIEDEMA, F, REISS, P

“…Unusual clinical inflammatory syndromes associated with underlying previously unrecognized opportunistic infections are increasingly being noted shortly after…”
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Immunophenotyping of blood lymphocytes at birth, during childhood, and during adulthood in HIV-1-uninfected Ethiopians by Tsegaye, Aster, Wolday, Dawit, Otto, Sigrid, Petros, Beyene, Assefa, Tsehai, Alebachew, Tsegaye, Hailu, Ermias, Adugna, Fekadu, Measho, Worku, Dorigo, Wendelien, Fontanet, Arnaud L, Baarle, Debbie van, Miedema, Frank

“…To obtain more insight into blood lymphocyte subpopulations of Ethiopians, we studied the immunologic profile of children and neonates and compared these data…”
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Tuberculin Skin Test Conversion and Reactivity Rates among Adults with and without Human Immunodeficiency Virus in Urban Settings in Ethiopia by Tegbaru, Belete, Wolday, Dawit, Messele, Tsehaynesh, Legesse, Mengistu, Mekonnen, Yared, Miedema, Frank, van Baarle, Debbie

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Immune Reconstitution after 2 Years of Successful Potent Antiretroviral Therapy in Previously Untreated Human Immunodeficiency Virus Type 1-Infected Adults by Notermans, Daan W., Pakker, Nadine G., Hamann, Dörte, Foudraine, Norbert A., Kauffmann, Robert H., Meenhorst, Pieter L., Goudsmit, Jaap, Roos, Marijke T. L., Schellekens, Peter T. A., Miedema, Frank, Danner, Sven A.

“…Today's antiretroviral combination regimens can induce significant and sustained decreases in human immunodeficiency virus (HIV)-RNA levels, allowing the…”
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Prepare PhD holders for different career tracks by van den Broek, Theo, Prakken, Berent, Miedema, Frank

“…Letter to the Editor…”
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Fewer numbers, better science by Benedictus, Rinze, Miedema, Frank, Ferguson, Mark W. J.

“…Scientific quality is hard to define, and numbers are easy to look at. But bibliometrics are warping science — encouraging quantity over quality. Leaders at…”
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Prediction of Residual Time to AIDS and Death Based on Markers and Cofactors by Geskus, Ronald B, Miedema, Frank A, Goudsmit, Jaap, Reiss, Peter, Schuitemaker, Hanneke, Coutinho, Roel A

“…A model was constructed that estimates the probability of an HIV-infected individual developing AIDS or dying within a certain time span if left untreated,…”
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A brief history of HIV vaccine research : stepping back to the drawing board? by MIEDEMA, Frank

“…In September 2007, it was announced that the most promising HIV vaccine trial had to be stopped because it had failed to show the protection that was hoped…”
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Nonradioactive techniques for measurement of in vitro T-cell proliferation: alternatives to the [(3)H]thymidine incorporation assay by Messele, T, Roos, M T, Hamann, D, Koot, M, Fontanet, A L, Miedema, F, Schellekens, P T, Rinke de Wit, T F

“…T-cell proliferation is an important in vitro parameter of in vivo immune function and has been used as a prognostic marker of human immunodeficiency virus…”
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Maintenance of Peripheral Naive T Cells Is Sustained by Thymus Output in Mice but Not Humans by den Braber, Ineke, Mugwagwa, Tendai, Vrisekoop, Nienke, Westera, Liset, Mögling, Ramona, Bregje de Boer, Anne, Willems, Neeltje, Schrijver, Elise H.R., Spierenburg, Gerrit, Gaiser, Koos, Mul, Erik, Otto, Sigrid A., Ruiter, An F.C., Ackermans, Mariette T., Miedema, Frank, Borghans, José A.M., de Boer, Rob J., Tesselaar, Kiki

“…Parallels between T cell kinetics in mice and men have fueled the idea that a young mouse is a good model system for a young human, and an old mouse, for an…”
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