Search Results - "MIDDELKOOP, ESTHER"

Antibacterial and safety tests of a flexible cold atmospheric plasma device for the stimulation of wound healing by Boekema, Bouke, Stoop, Matthea, Vlig, Marcel, van Liempt, Jos, Sobota, Ana, Ulrich, Magda, Middelkoop, Esther

“…Cold atmospheric plasma (CAP) devices generate an ionized gas with highly reactive species and electric fields at ambient air pressure and temperature. A…”
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Review: Lessons Learned From Clinical Trials Using Antimicrobial Peptides (AMPs) by Dijksteel, Gabrielle S, Ulrich, Magda M W, Middelkoop, Esther, Boekema, Bouke K H L

“…Antimicrobial peptides (AMPs) or host defense peptides protect the host against various pathogens such as yeast, fungi, viruses and bacteria. AMPs also display…”
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Updated Scar Management Practical Guidelines: Non-invasive and invasive measures by Monstrey, Stan, Middelkoop, Esther, Vranckx, Jan Jeroen, Bassetto, Franco, Ziegler, Ulrich E, Meaume, Sylvie, Téot, Luc

“…Summary Hypertrophic scars and keloids can be aesthetically displeasing and lead to severe psychosocial impairment. Many invasive and non-invasive options are…”
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Characteristics, treatments and outcomes in patients with severe burn wounds; a 10 year cohort study on acute and reconstructive treatment by Smit, Lucindi, Pijpe, Anouk, Nguyen, Cindy, Hartsuiker, Tara, Stoop, Matthea, Anouk van Heel, Bosma, Eelke, Cornelis H. van der Vlies, Paul P. M. van Zuijlen, van Baar, Margriet E, Middelkoop, Esther, Dutch Burn Repository group

“…Reports on treatment characteristics and long term outcomes for severe burns are scarce, while the need to compare outcomes of novel treatment modalities to…”
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Activation, function and content of platelets in burn patients by Marck, Roos E., van der Bijl, Ivo, Korsten, Herbert, Lorinser, Jos, de Korte, Dirk, Middelkoop, Esther

“…Burn injury has severe impact on the physiologic homeostasis. Platelet counts show a distinct course post-burn injury, with a nadir at day 3 followed by a…”
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Impact of facial burns: relationship between depressive symptoms, self-esteem and scar severity by Hoogewerf, Cornelis Johannes, MS.c, van Baar, Margriet Elisabeth, Ph.D, Middelkoop, Esther, Ph.D, van Loey, Nancy Elisa, Ph.D

“…Abstract Objective This study assessed the role of self-reported facial scar severity as a possible influencing factor on self-esteem and depressive symptoms…”
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Growth Factor Quantification of Platelet-Rich Plasma in Burn Patients Compared to Matched Healthy Volunteers by Marck, Roos E, Gardien, Kim L M, Vlig, Marcel, Breederveld, Roelf S, Middelkoop, Esther

“…Platelet rich plasma (PRP) is blood plasma with a platelet concentration above baseline. When activated, PRP releases growth factors involved in all stages of…”
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An objective device for measuring surface roughness of skin and scars by Bloemen, Monica C.T., MD, van Gerven, Maaike S., MS, van der Wal, Martijn B.A., MD, Verhaegen, Pauline D.H.M., MD, Middelkoop, Esther, PhD

“…Background Scar formation remains a major clinical problem; therefore, various therapies have been developed to improve scar quality. To evaluate the…”
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Outcome of Burns Treated With Autologous Cultured Proliferating Epidermal Cells: A Prospective Randomized Multicenter Intrapatient Comparative Trial by Gardien, Kim L M, Marck, Roos E, Bloemen, Monica C T, Waaijman, Taco, Gibbs, Sue, Ulrich, Magda M W, Middelkoop, Esther

“…Standard treatment for large burns is transplantation with meshed split skin autografts (SSGs). A disadvantage of this treatment is that healing is accompanied…”
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Short- and Long-term Outcomes of an Acellular Dermal Substitute versus Standard of Care in Burns and Reconstructions: A Phase I/II Intrapatient Randomized Controlled Trial by Gardien, Kim L. M., Pijpe, Anouk, Brouwer, Katrien M., Stoop, Matthea, Singh, Simarjeet K., Timmermans, Floyd W., Vlig, Marcel, van Zuijlen, Paul P. M., Middelkoop, Esther

“…OBJECTIVEDermal substitutes promote dermal regeneration and improve scar quality, but knowledge gaps remain regarding their efficacy and indications for use…”
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Differences in collagen architecture between keloid, hypertrophic scar, normotrophic scar, and normal skin: An objective histopathological analysis by Verhaegen, Pauline D. H. M., Van Zuijlen, Paul P. M., Pennings, Noor M., Van Marle, Jan, Niessen, Frank B., Van Der Horst, Chantal M. A. M., Middelkoop, Esther

“…ABSTRACT Normotrophic, hypertrophic, and keloidal scars are different types of scar formation, which all need a different approach in treatment. Therefore, it…”
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Monocytes and T cells incorporated in full skin equivalents to study innate or adaptive immune reactions after burn injury by Mulder, Patrick P.G., Vlig, Marcel, Elgersma, Anouk, Rozemeijer, Lotte, Mastenbroek, Leonore S., Middelkoop, Esther, Joosten, Irma, Koenen, Hans J.P.M., Boekema, Bouke K.H.L.

“…IntroductionThermal injury often leads to prolonged and excessive inflammation, which hinders the recovery of patients. There is a notable absence of suitable…”
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Safety and bactericidal efficacy of cold atmospheric plasma generated by a flexible surface Dielectric Barrier Discharge device against Pseudomonas aeruginosa in vitro and in vivo by Dijksteel, Gabrielle S, Ulrich, Magda M W, Vlig, Marcel, Sobota, Ana, Middelkoop, Esther, Boekema, Bouke K H L

“…Cold atmospheric plasma (CAP), which is ionized gas produced at atmospheric pressure, could be a novel and potent antimicrobial therapy for the treatment of…”
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Improved and standardized method for assessing years lived with disability after burns and its application to estimate the non-fatal burden of disease of burn injuries in Australia, New Zealand and the Netherlands by Spronk, Inge, Edgar, Dale W, van Baar, Margriet E, Wood, Fiona M, Van Loey, Nancy E E, Middelkoop, Esther, Renneberg, Babette, Öster, Caisa, Orwelius, Lotti, Moi, Asgjerd L, Nieuwenhuis, Marianne, van der Vlies, Cornelis H, Polinder, Suzanne, Haagsma, Juanita A

“…Burden of disease estimates are an important resource in public health. Currently, robust estimates are not available for the burn population. Our objectives…”
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Biological background of dermal substitutes by van der Veen, Vincent C, van der Wal, Martijn B.A, van Leeuwen, Michiel C.E, Ulrich, Magda M.W, Middelkoop, Esther

“…Abstract Dermal substitutes are of major importance in treating full thickness skin defects, both in acute and chronic wounds. In this review we will outline…”
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Prevention and curative management of hypertrophic scar formation by Bloemen, Monica C.T, van der Veer, Willem M, Ulrich, Magda M.W, van Zuijlen, Paul P.M, Niessen, Frank B, Middelkoop, Esther

“…Abstract Although hypertrophic scarring commonly occurs following burns, many aspects such as incidence of and optimal treatment for scar hypertrophy remain…”
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Outcome after burns: An observational study on burn scar maturation and predictors for severe scarring by van der Wal, Martijn B. A., Vloemans, Jos F. P. M., Tuinebreijer, Wim E., van de Ven, Peter, van Unen, Ella, van Zuijlen, Paul P. M., Middelkoop, Esther

“…Long‐term outcome of burn scars as well as the relation with clinically relevant parameters has not been studied quantitatively. Therefore, we conducted a…”
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Adaptation of the dermal collagen structure of human skin and scar tissue in response to stretch: An experimental study by Verhaegen, Pauline D., Schouten, Hennie J., Tigchelaar-Gutter, Wikky, van Marle, Jan, van Noorden, Cornelis J., Middelkoop, Esther, van Zuijlen, Paul P.

“…Surgeons are often faced with large defects that are difficult to close. Stretching adjacent skin can facilitate wound closure. In clinical practice,…”
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An in silico modeling approach to understanding the dynamics of the post-burn immune response by Korkmaz, H Ibrahim, Sheraton, Vivek M, Bumbuc, Roland V, Li, Meifang, Pijpe, Anouk, Mulder, Patrick P G, Boekema, Bouke K H L, de Jong, Evelien, Papendorp, Stephan G F, Brands, Ruud, Middelkoop, Esther, Sloot, Peter M A, van Zuijlen, Paul P M

“…Burns are characterized by a massive and prolonged acute inflammation, which persists for up to months after the initial trauma. Due to the complexity of the…”
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SPS-neutralization in tissue samples for efficacy testing of antimicrobial peptides by Dijksteel, Gabrielle Sherella, Nibbering, Peter H, Ulrich, Magda M W, Middelkoop, Esther, Boekema, Bouke K H L

“…Accurate determination of the efficacy of antimicrobial agents requires neutralization of residual antimicrobial activity in the samples before microbiological…”
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