Search Results - "MIDDELDORP, Jaap M"

Nontemplated Nucleotide Additions Distinguish the Small RNA Composition in Cells from Exosomes by Koppers-Lalic, Danijela, Hackenberg, Michael, Bijnsdorp, Irene V., van Eijndhoven, Monique A.J., Sadek, Payman, Sie, Daud, Zini, Nicoletta, Middeldorp, Jaap M., Ylstra, Bauke, de Menezes, Renee X., Würdinger, Thomas, Meijer, Gerrit A., Pegtel, D. Michiel

“…Functional biomolecules, including small noncoding RNAs (ncRNAs), are released and transmitted between mammalian cells via extracellular vesicles (EVs),…”
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Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling by Verweij, Frederik Johannes, Bebelman, Maarten P, Jimenez, Connie R, Garcia-Vallejo, Juan J, Janssen, Hans, Neefjes, Jacques, Knol, Jaco C, de Goeij-de Haas, Richard, Piersma, Sander R, Baglio, S Rubina, Verhage, Matthijs, Middeldorp, Jaap M, Zomer, Anoek, van Rheenen, Jacco, Coppolino, Marc G, Hurbain, Ilse, Raposo, Graça, Smit, Martine J, Toonen, Ruud F G, van Niel, Guillaume, Pegtel, D Michiel

“…Exosomes are small endosome-derived extracellular vesicles implicated in cell-cell communication and are secreted by living cells when multivesicular bodies…”
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Functional delivery of viral miRNAs via exosomes by Pegtel, D. Michiel, Cosmopoulos, Katherine, Thorley-Lawson, David A, van Eijndhoven, Monique A.J, Hopmans, Erik S, Lindenberg, Jelle L, de Gruijl, Tanja D, Würdinger, Thomas, Middeldorp, Jaap M

“…Noncoding regulatory microRNAs (miRNAs) of cellular and viral origin control gene expression by repressing the translation of mRNAs into protein…”
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Sequence Variation of Epstein-Barr Virus: Viral Types, Geography, Codon Usage, and Diseases by Correia, Samantha, Bridges, Ray, Wegner, Fanny, Venturini, Cristina, Palser, Anne, Middeldorp, Jaap M, Cohen, Jeffrey I, Lorenzetti, Mario A, Bassano, Irene, White, Robert E, Kellam, Paul, Breuer, Judith, Farrell, Paul J

“…One hundred thirty-eight new Epstein-Barr virus (EBV) genome sequences have been determined. One hundred twenty-five of these and 116 from previous reports…”
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Vesicle‐bound EBV‐BART13‐3p miRNA in circulation distinguishes nasopharyngeal from other head and neck cancer and asymptomatic EBV‐infections by Ramayanti, Octavia, Verkuijlen, Sandra A.W.M., Novianti, Putri, Scheepbouwer, Chantal, Misovic, Branislav, Koppers‐Lalic, Danijela, Weering, Jan, Beckers, Lisa, Adham, Marlinda, Martorelli, Debora, Middeldorp, Jaap M., Pegtel, Dirk Michiel

“…Cell‐free microRNA (miRNA) in biofluids released by tumors in either protein or vesicle‐bound form, represent promising minimally‐invasive cancer biomarkers…”
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Natural Variation of Epstein-Barr Virus Genes, Proteins, and Primary MicroRNA by Correia, Samantha, Palser, Anne, Elgueta Karstegl, Claudio, Middeldorp, Jaap M, Ramayanti, Octavia, Cohen, Jeffrey I, Hildesheim, Allan, Fellner, Maria Dolores, Wiels, Joelle, White, Robert E, Kellam, Paul, Farrell, Paul J

“…Viral gene sequences from an enlarged set of about 200 Epstein-Barr virus (EBV) strains, including many primary isolates, have been used to investigate…”
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The Epstein-Barr Virus BART miRNA Cluster of the M81 Strain Modulates Multiple Functions in Primary B Cells by Lin, Xiaochen, Tsai, Ming-Han, Shumilov, Anatoliy, Poirey, Remy, Bannert, Helmut, Middeldorp, Jaap M, Feederle, Regina, Delecluse, Henri-Jacques

“…The Epstein-Barr virus (EBV) is a B lymphotropic virus that infects the majority of the human population. All EBV strains transform B lymphocytes, but some…”
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Evolution of functional antibodies following acute Epstein-Barr virus infection by Karsten, Christina B, Bartsch, Yannic C, Shin, Sally A, Slein, Matthew D, Heller, Howard M, Kolandaivelu, Kumaran, Middeldorp, Jaap M, Alter, Galit, Julg, Boris

“…While Epstein-Barr virus causes mostly asymptomatic infection, associated malignancies, and autoimmune and lymphoproliferative diseases occur. To dissect the…”
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Epstein-Barr Virus-Encoded BARF1 Promotes Proliferation of Gastric Carcinoma Cells through Regulation of NF-κB by Chang, Mee Soo, Kim, Dong Ha, Roh, Jin Kyung, Middeldorp, Jaap M, Kim, Yang Soo, Kim, Sunghan, Han, Seungbong, Kim, Chul Woo, Lee, Byung Lan, Kim, Woo Ho, Woo, Jun Hee

“…OA  Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+…”
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Epstein-barr virus latency in B cells leads to epigenetic repression and CpG methylation of the tumour suppressor gene Bim by Paschos, Kostas, Smith, Paul, Anderton, Emma, Middeldorp, Jaap M, White, Robert E, Allday, Martin J

“…In human B cells infected with Epstein-Barr virus (EBV), latency-associated virus gene products inhibit expression of the pro-apoptotic Bcl-2-family member Bim…”
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Viral miRNAs exploiting the endosomal–exosomal pathway for intercellular cross-talk and immune evasion by Pegtel, D. Michiel, van de Garde, Martijn D.B., Middeldorp, Jaap M.

“…The class of persistent gamma-herpesviruses has developed a variety of strategies that exploit host-cell regulatory pathways to ensure a long-lasting,…”
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Epstein-Barr Virus Serology as a Potential Screening Marker for Nasopharyngeal Carcinoma among High-Risk Individuals from Multiplex Families in Taiwan by COGHILL, Anna E, HSU, Wan-Lun, HILDESHEIM, Allan, PFEIFFER, Ruth M, JUWANA, Hedy, YU, Kelly J, LOU, Pei-Jen, WANG, Cheng-Ping, CHEN, Jen-Yang, CHEN, Chien-Jen, MIDDELDORP, Jaap M

“…Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV)-associated cancer that is highly treatable when diagnosed early, with 5-year disease-free…”
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Activation of lytic cycle of Epstein-Barr virus by suberoylanilide hydroxamic acid leads to apoptosis and tumor growth suppression of nasopharyngeal carcinoma by Hui, K.F., Ho, Dona N., Tsang, C.M., Middeldorp, Jaap M., Tsao, George S.W., Chiang, Alan K.S.

“…Nasopharyngeal carcinoma (NPC) is strongly associated with Epstein‐Barr virus (EBV). We reported that suberoylanilide hydroxamic acid (SAHA) induced EBV lytic…”
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Seroprevalence of IgA anti Epstein-Barr virus is high among family members of nasopharyngeal cancer patients and individuals presenting with chronic complaints in head and neck area by Hutajulu, Susanna Hilda, Fachiroh, Jajah, Argy, Gabriella, Indrasari, Sagung Rai, Indrawati, Luh Putu Lusy, Paramita, Dewi Kartikawati, Jati, Theodola Baning Rahayu, Middeldorp, Jaap M

“…Epstein-Barr (EBV) infection and presence of a nasopharyngeal cancer (NPC) case in the family increases the risk of developing NPC. Aberrant anti-EBV…”
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Epstein‐Barr virus infection in immortalized nasopharyngeal epithelial cells: Regulation of infection and phenotypic characterization by Tsang, Chi Man, Zhang, Guitao, Seto, Eri, Takada, Kenzo, Deng, Wen, Yip, Yim Ling, Man, Cornelia, Hau, Pok Man, Chen, Honglin, Cao, Ya, Lo, Kwok Wai, Middeldorp, Jaap M., Cheung, Annie Lai Man, Tsao, Sai Wah

“…Epstein‐Barr virus (EBV) infection has been postulated to be an early event involved in the pathogenesis of nasopharyngeal carcinomas (NPC). The lack of…”
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Impact of Epstein-Barr virus co-infection on natural acquired Plasmodium vivax antibody response by Dias, Michelle H. F., Guimarães, Luiz F. F., Barcelos, Matheus G., Moreira, Eduardo U. M., do Nascimento, Maria F. A., de Souza, Taís N., Pires, Camilla V., Monteiro, Talita A. F., Middeldorp, Jaap M., Soares, Irene S., Fontes, Cor J. F., Ntumngia, Francis B., Adams, John H., Kano, Flora S., Carvalho, Luzia H.

“…Background The simultaneous infection of Plasmodium falciparum and Epstein-Barr virus (EBV) could promote the development of the aggressive endemic Burkitt’s…”
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BamHI-A rightward frame 1, an Epstein-Barr virus-encoded oncogene and immune modulator by Hoebe, Eveline K., Le Large, Tessa Y. S., Greijer, Astrid E., Middeldorp, Jaap M.

“…SUMMARY Epstein–Barr virus (EBV) causes several benign and malignant disorders of lymphoid and epithelial origin. EBV‐related tumors display distinct patterns…”
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Epstein-Barr Virus DNA Load in Nasopharyngeal Brushings and Whole Blood in Nasopharyngeal Carcinoma Patients before and after Treatment by ADHAM, Marlinda, GREIJER, Astrid E, ATMAKUSUMAH, Djumhana, STEVENS, Servi J. C, HERMANI, Bambang, BING TAN, I, MIDDELDORP, Jaap M, VERKUIJLEN, Sandra A. W. M, JUWANA, Hedy, FLEIG, Sabine, RACHMADI, Lisnawati, MALIK, Octavia, KURNIAWAN, A. N, ROEZIN, Averdi, GONDHOWIARDJO, Soehartati

“…Nasopharyngeal carcinoma (NPC) is consistently associated with Epstein-Barr virus (EBV) and highly prevalent in Indonesia. EBV-DNA load can be used for early…”
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Demonstration of the Burkitt's Lymphoma Epstein-Barr Virus Phenotype in Dividing Latently Infected Memory Cells in vivo by Hochberg, Donna, Middeldorp, Jaap M., Catalina, Michelle, Sullivan, John L., Luzuriaga, Katherine, Thorley-Lawson, David A.

“…Epstein-Barr virus (EBV) is a herpesvirus that establishes a lifelong, persistent infection. It was first discovered in the tumor Burkitt's lymphoma (BL)…”
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High Levels of EBV-Encoded RNA 1 (EBER1) Trigger Interferon and Inflammation-Related Genes in Keratinocytes Expressing HPV16 E6/E7 by Aromseree, Sirinart, Middeldorp, Jaap M, Pientong, Chamsai, van Eijndhoven, Monique, Ramayanti, Octavia, Lougheed, Sinéad M, Pegtel, D Michiel, Steenbergen, Renske D M, Ekalaksananan, Tipaya

“…Different types of cells infected with Epstein-Barr virus (EBV) can release exosomes containing viral components that functionally affect neighboring cells…”
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