Search Results - "MICHAËLSSON, Jakob"

Emerging insights into natural killer cells in human peripheral tissues by Björkström, Niklas K., Ljunggren, Hans-Gustaf, Michaëlsson, Jakob

“…Key Points Natural killer (NK) cells are present in most human tissues. A high frequency of NK cells can be found in peripheral blood, the lungs, the uterus…”
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Distinct Alterations in the Composition of Mucosal Innate Lymphoid Cells in Newly Diagnosed and Established Crohn’s Disease and Ulcerative Colitis by Forkel, Marianne, van Tol, Sophie, Höög, Charlotte, Michaëlsson, Jakob, Almer, Sven, Mjösberg, Jenny

“…Abstract Background and Aims Innate lymphoid cells [ILC] have been suggested to play a role in inflammatory bowel disease [IBD]. Here, we investigated the ILC…”
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Education of human natural killer cells by activating killer cell immunoglobulin-like receptors by Fauriat, Cyril, Ivarsson, Martin A., Ljunggren, Hans-Gustaf, Malmberg, Karl-Johan, Michaëlsson, Jakob

“…Expression of inhibitory killer cell immunoglobulin-like receptors (KIRs) specific for self–major histocompatibility complex (MHC) class I molecules provides…”
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Human lung natural killer cells are predominantly comprised of highly differentiated hypofunctional CD69− CD56dim cells by Marquardt, Nicole, PhD, Kekäläinen, Eliisa, MD, PhD, Chen, Puran, MD, Kvedaraite, Egle, MD, Wilson, Jennifer N., BSc, Ivarsson, Martin A., PhD, Mjösberg, Jenny, PhD, Berglin, Lena, PhD, Säfholm, Jesper, PhD, Manson, Martijn L., PharmD, PhD, Adner, Mikael, PhD, Al-Ameri, Mamdoh, MD, Bergman, Per, MD, PhD, Orre, Ann-Charlotte, MD, Svensson, Mattias, PhD, Dahlén, Barbro, MD, PhD, Dahlén, Sven-Erik, MD, PhD, Ljunggren, Hans-Gustaf, MD, PhD, Michaëlsson, Jakob, PhD

“…Background In contrast to the extensive knowledge about human natural killer (NK) cells in peripheral blood, relatively little is known about NK cells in the…”
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Regulation of T Cell Responses in the Developing Human Fetus by Michaelsson, Jakob, Mold, Jeff E, McCune, Joseph M, Nixon, Douglas F

“…Although human T cells enter the peripheral lymphoid tissues early during fetal development, the adaptive immune system in the fetus has largely been regarded…”
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Analysis of allelic expression patterns in clonal somatic cells by single-cell RNA–seq by Reinius, Björn, Mold, Jeff E, Ramsköld, Daniel, Deng, Qiaolin, Johnsson, Per, Michaëlsson, Jakob, Frisén, Jonas, Sandberg, Rickard

“…Rickard Sandberg and colleagues use allele-sensitive single-cell RNA–seq on primary mouse fibroblasts and human T cells to study clonal and dynamic monoallelic…”
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Human CD4+ CD25+ Regulatory T Cells Control T-Cell Responses to Human Immunodeficiency Virus and Cytomegalovirus Antigens by AANDAHL, Einar M, MICHAËLSSON, Jakob, MORETTO, Walter J, HECHT, Frederick M, NIXON, Douglas F

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Activating killer cell Ig-like receptors in health and disease by Ivarsson, Martin A, Michaëlsson, Jakob, Fauriat, Cyril

“…Expression of non-rearranged HLA class I-binding receptors characterizes human and mouse NK cells. The postulation of the missing-self hypothesis some 30 years…”
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The inflammatory milieu in the rheumatic joint reduces regulatory T‐cell function by Herrath, Jessica, Müller, Malin, Amoudruz, Petra, Janson, Peter, Michaëlsson, Jakob, Larsson, Per T., Trollmo, Christina, Raghavan, Sukanya, Malmström, Vivianne

“…Regulatory T cells (Tregs) are important for maintaining immune homeostasis, but many studies suggest that Tregs are functionally impaired in autoimmune and…”
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Human Immunodeficiency Virus Type 1 (HIV-1)-Specific CD8 + T EMRA Cells in Early Infection Are Linked to Control of HIV-1 Viremia and Predict the Subsequent Viral Load Set Point by Northfield, John W., Loo, Christopher P., Barbour, Jason D., Spotts, Gerald, Hecht, Frederick M., Klenerman, Paul, Nixon, Douglas F., Michaëlsson, Jakob

“…CD8 + T cells are believed to play an important role in the control of human immunodeficiency virus type 1 (HIV-1) infection. However, despite intensive…”
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A signal peptide derived from hsp60 binds HLA-E and interferes with CD94/NKG2A recognition by Michaëlsson, Jakob, Teixeira de Matos, Cristina, Achour, Adnane, Lanier, Lewis L, Kärre, Klas, Söderström, Kalle

“…Human histocompatibility leukocyte antigen (HLA)-E is a nonclassical major histocompatibility complex (MHC) class I molecule which presents a restricted set of…”
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Human lung natural killer cells are predominantly comprised of highly differentiated hypofunctional CD69 - CD56 dim cells by Marquardt, Nicole, Kekäläinen, Eliisa, Chen, Puran, Kvedaraite, Egle, Wilson, Jennifer N, Ivarsson, Martin A, Mjösberg, Jenny, Berglin, Lena, Säfholm, Jesper, Manson, Martijn L, Adner, Mikael, Al-Ameri, Mamdoh, Bergman, Per, Orre, Ann-Charlotte, Svensson, Mattias, Dahlén, Barbro, Dahlén, Sven-Erik, Ljunggren, Hans-Gustaf, Michaëlsson, Jakob

“…In contrast to the extensive knowledge about human natural killer (NK) cells in peripheral blood, relatively little is known about NK cells in the human lung…”
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Activating and inhibitory receptors on synovial fluid natural killer cells of arthritis patients: role of CD94/NKG2A in control of cytokine secretion by de Matos, Cristina Teixeira, Berg, Louise, Michaëlsson, Jakob, Felländer-Tsai, Li, Kärre, Klas, Söderström, Kalle

“…Natural killer (NK) cells are activated early during inflammatory events and contribute to the shaping of the ensuing adaptive immune response. To further…”
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Expansion of CD56− NK cells in chronic HCV/HIV-1 co-infection: Reversion by antiviral treatment with pegylated IFNα and ribavirin by Gonzalez, Veronica D, Falconer, Karolin, Michaëlsson, Jakob, Moll, Markus, Reichard, Olle, Alaeus, Annette, Sandberg, Johan K

“…Abstract Co-infection with HCV and HIV-1 is a problem of increasing importance and the role of innate cellular immunity in this co-infection is incompletely…”
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Distinct developmental pathways from blood monocytes generate human lung macrophage diversity by Evren, Elza, Ringqvist, Emma, Tripathi, Kumar Parijat, Sleiers, Natalie, Rives, Inés Có, Alisjahbana, Arlisa, Gao, Yu, Sarhan, Dhifaf, Halle, Tor, Sorini, Chiara, Lepzien, Rico, Marquardt, Nicole, Michaëlsson, Jakob, Smed-Sörensen, Anna, Botling, Johan, Karlsson, Mikael C.I., Villablanca, Eduardo J., Willinger, Tim

“…The study of human macrophages and their ontogeny is an important unresolved issue. Here, we use a humanized mouse model expressing human cytokines to dissect…”
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Killer Cell Immunoglobulin-like Receptor Workshop: Insights into Evolution, Genetics, Function, and Translation by Malmberg, Karl-Johan, Michaëlsson, Jakob, Parham, Peter, Ljunggren, Hans-Gustaf

“…The seventh killer cell immunoglobulin-like receptor (KIR) workshop was held at Tammsvik, Stockholm, Sweden, in the summer of 2011. This intimate and isolated…”
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Identification of a Human Natural Killer Cell Lineage-Restricted Progenitor in Fetal and Adult Tissues by Renoux, Virginie M., Zriwil, Alya, Peitzsch, Claudia, Michaëlsson, Jakob, Friberg, Danielle, Soneji, Shamit, Sitnicka, Ewa

“…Natural killer (NK) cells are cytotoxic lymphocytes and play a vital role in controlling viral infections and cancer. In contrast to B and T lymphopoiesis…”
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Unique transcriptional and protein-expression signature in human lung tissue-resident NK cells by Marquardt, Nicole, Kekäläinen, Eliisa, Chen, Puran, Lourda, Magda, Wilson, Jennifer N., Scharenberg, Marlena, Bergman, Per, Al-Ameri, Mamdoh, Hård, Joanna, Mold, Jeffrey E., Ljunggren, Hans-Gustaf, Michaëlsson, Jakob

“…Human lung tissue-resident NK cells (trNK cells) are likely to play an important role in host responses towards viral infections, inflammatory conditions and…”
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T-bet and Eomes are differentially linked to the exhausted phenotype of CD8+ T cells in HIV infection by Buggert, Marcus, Tauriainen, Johanna, Yamamoto, Takuya, Frederiksen, Juliet, Ivarsson, Martin A, Michaëlsson, Jakob, Lund, Ole, Hejdeman, Bo, Jansson, Marianne, Sönnerborg, Anders, Koup, Richard A, Betts, Michael R, Karlsson, Annika C

“…CD8(+) T cell exhaustion represents a major hallmark of chronic HIV infection. Two key transcription factors governing CD8(+) T cell differentiation, T-bet and…”
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NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs by Béziat, Vivien, Liu, Lisa L., Malmberg, Jenny-Ann, Ivarsson, Martin A., Sohlberg, Ebba, Björklund, Andreas T., Retière, Christelle, Sverremark-Ekström, Eva, Traherne, James, Ljungman, Per, Schaffer, Marie, Price, David A., Trowsdale, John, Michaëlsson, Jakob, Ljunggren, Hans-Gustaf, Malmberg, Karl-Johan

“…Human natural killer (NK) cells are functionally regulated by killer cell immunoglobulin-like receptors (KIRs) and their interactions with HLA class I…”
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