Search Results - "MEURS, K. M"

Prevalence of an angiotensin-converting enzyme gene variant in dogs by Adin, D. B, Atkins, C. E, Friedenberg, S. G, Stern, J. A, Meurs, K. M

“…Abstract Background Genetic heterogeneity of the canine angiotensin converting enzyme (ACE) gene is functionally important because the degree of aldosterone…”
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Identification of PDE5A:E90K: A Polymorphism in the Canine Phosphodiesterase 5A Gene Affecting Basal cGMP Concentrations of Healthy Dogs by Stern, J. A, Reina‐Doreste, Y, Chdid, L, Meurs, K. M

“…BACKGROUND: Cyclic guanosine monophosphate (cGMP)‐specific phosphodiesterase (PDE5A) is the target of phosphodiesterase inhibitors such as sildenafil…”
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Genotype imputation in the domestic dog by Friedenberg, S. G., Meurs, K. M.

“…Application of imputation methods to accurately predict a dense array of SNP genotypes in the dog could provide an important supplement to current analyses of…”
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Identification of DNA variants in the canine beta-1 adrenergic receptor gene by Maran, B.A., Mealey, K.L., Lahmers, S.M., Nelson, O.L., Meurs, K.M.

“…Beta-adrenergic receptor antagonists are utilized for the management of several cardiac diseases in the dog. In humans the beneficial effects of…”
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Clinical outcome of idiopathic juvenile ventricular arrhythmias in 25 dogs by Reuter, A., DeFrancesco, T.C., Robertson, J.B., Meurs, K.M.

“…Juvenile ventricular arrhythmias in the absence of structural heart disease have been characterized in a small number of canine breeds with limited long-term…”
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Familial hypertrophic cardiomyopathy in Maine coon cats : An animal model of human disease by KITTLESON, M. D, MEURS, K. M, MUNRO, M. J, KITTLESON, J. A, LIU, S.-K, PION, P. D, TOWBIN, J. A

“…A naturally occurring animal model of familial hypertrophic cardiomyopathy (FHCM) is lacking. We identified a family of Maine coon cats with HCM and developed…”
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The role of vector-borne pathogens and cardiac Striatin genotype on survival in boxer dogs with arrhythmogenic right ventricular cardiomyopathy by Ditzler, B., Lashnits, E., Meurs, K.M., Maggi, R.G., Yata, M., Neupane, P., Breitschwerdt, E.B.

“…Risk factors for severe disease in boxer dogs with arrhythmogenic right ventricular cardiomyopathy (ARVC) are not well understood. This study's objective was…”
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Absence of known feline MYH7 and MYBPC3 variants in a diverse cohort of cats with hypertrophic cardiomyopathy by O'Donnell, K., Adin, D., Atkins, C. E., DeFrancesco, T., Keene, B. W., Tou, S., Meurs, K. M.

“…Summary Hypertrophic cardiomyopathy (HCM) is the most common cause of heart disease in the domestic cat with a genetic predisposition in a few breeds. In the…”
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Association of diet with clinical outcomes in dogs with dilated cardiomyopathy and congestive heart failure by Walker, A.L., DeFrancesco, T.C., Bonagura, J.D., Keene, B.W., Meurs, K.M., Tou, S.P., Kurtz, K., Aona, B., Barron, L., McManamey, A., Robertson, J., Adin, D.B.

“…Dilated cardiomyopathy (DCM) in dogs has been associated with feeding of grain-free (GF), legume-rich diets. Some dogs with presumed diet-associated DCM have…”
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Lymphocyte Subsets in the Adrenal Glands of Dogs With Primary Hypoadrenocorticism by Friedenberg, S. G., Brown, D. L., Meurs, K. M., Law, J. McHugh

“…Primary hypoadrenocorticism, or Addison’s disease, is an autoimmune condition common in certain dog breeds that leads to the destruction of the adrenal cortex…”
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Sudden Death Associated with QT Interval Prolongation and KCNQ1 Gene Mutation in a Family of English Springer Spaniels by Ware, W.A., Reina‐Doreste, Y., Stern, J.A., Meurs, K.M.

“…Background A 5‐year‐old, healthy English Springer Spaniel died suddenly 4 months after delivering a litter of 7 puppies. Within 4 months of the dam's death, 3…”
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Evaluation of genes associated with human myxomatous mitral valve disease in dogs with familial myxomatous mitral valve degeneration by Meurs, K.M., Friedenberg, S.G., Williams, B., Keene, B.W., Atkins, C.E., Adin, D., Aona, B., DeFrancesco, T., Tou, S., Mackay, T.

“…•We hypothesized that a mutation associated with human mitral valve disease (MMVD) is associated with canine disease.•Sequenced DNA of MMVD Cavalier King…”
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A review of the underlying genetics and emerging therapies for canine cardiomyopathies by Shen, L., Estrada, A.H., Meurs, K.M., Sleeper, M., Vulpe, C., Martyniuk, C.J., Pacak, C.A.

“…Cardiomyopathies such as dilated cardiomyopathy and arrhythmogenic right ventricular cardiomyopathy are common in large breed dogs and carry an overall poor…”
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Natural History of Arrhythmogenic Right Ventricular Cardiomyopathy in the Boxer Dog: A Prospective Study by Meurs, K.M, Stern, J.A, Reina‐Doreste, Y, Spier, A.W, Koplitz, S.L, Baumwart, R.D

“…BACKGROUND: Boxer arrhythmogenic right ventricular cardiomyopathy (ARVC) is a disease that may result in sudden death or heart failure. HYPOTHESIS/OBJECTIVES:…”
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Myxomatous mitral valve disease in the miniature poodle: A retrospective study by Meurs, K.M., Adin, D., O’Donnell, K., Keene, B.W., Atkins, C.E., DeFrancesco, T., Tou, S.

“…•Mxyomatous mitral valve degeneration (MMVD) in the miniature poodle was characterized.•Medical records from 32 miniature poodles with MMVD diagnosed at a…”
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Association of Dilated Cardiomyopathy with the Striatin Mutation Genotype in Boxer Dogs by Meurs, K.M., Stern, J.A., Sisson, D.D., Kittleson, M.D., Cunningham, S.M., Ames, M.K., Atkins, C.E., DeFrancesco, T., Hodge, T.E., Keene, B.W., Reina Doreste, Y., Leuthy, M., Motsinger-Reif, A.A., Tou, S.P.

“…BACKGROUND: Myocardial disease in the Boxer dog is characterized by 1 of 2 clinical presentations, dilated cardiomyopathy (DCM) characterized by ventricular…”
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Prevalence of the Myosin-Binding Protein C Mutation in Maine Coon Cats by Fries, R., Heaney, A.M., Meurs, K.M.

“…Background: An autosomal dominant mutation has been identified in the myosin‐binding protein C (MYBPC3) gene of Maine Coon cats. This mutation changes a…”
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Analysis of 8 Sarcomeric Candidate Genes for Feline Hypertrophic Cardiomyopathy Mutations in Cats with Hypertrophic Cardiomyopathy by Meurs, K.M, Norgard, M.M, Kuan, M, Haggstrom, J, Kittleson, M

“…Background: Hypertrophic cardiomyopathy (HCM) is the most common heart disease in cats. Causative mutations have been identified in the Maine Coon (MC) and…”
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Arrhythmogenic right ventricular cardiomyopathy causing sudden cardiac death in boxer dogs: A new animal model of human disease by BASSO, Cristina, FOX, Philip R, MEURS, Kathryn M, TOWBIN, Jeffrey A, SPIER, Alan W, CALABRESE, Fiorella, MARON, Barry J, THIENE, Gaetano

“…Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a primary familial heart muscle disease associated with substantial cardiovascular morbidity and risk…”
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Familial subvalvular aortic stenosis in golden retrievers: inheritance and echocardiographic findings by Stern, J. A., Meurs, K. M., Nelson, O. L., Lahmers, S. M., Lehmkuhl, L. B.

“…Objectives: To describe the echocardiographic findings and pedigree analysis of golden retrievers with subvalvular aortic stenosis. Methods: Seventy‐three…”
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