Search Results - "METZGER, Ralf"

MALAT-1, a novel noncoding RNA, and thymosin β4 predict metastasis and survival in early-stage non-small cell lung cancer by PING JI, DIEDERICHS, Sven, THOMAS, Michael, BERDEL, Wolfgang E, SERVE, Hubert, MÜLLER-TIDOW, Carsten, WENBING WANG, BÖING, Sebastian, METZGER, Ralf, SCHNEIDER, Paul M, TIDOW, Nicola, BRANDT, Burkhard, BUERGER, Horst, BULK, Etmar

“…Early-stage non-small cell lung cancer (NSCLC) can be cured by surgical resection, but a substantial fraction of patients ultimately dies due to distant…”
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Diagnostic marker signature for esophageal cancer from transcriptome analysis by Warnecke-Eberz, Ute, Metzger, Ralf, Hölscher, Arnulf H., Drebber, Uta, Bollschweiler, Elfriede

“…Esophageal cancer is often diagnosed at an advanced stage. Diagnostic markers are needed for achieving a cure in esophageal cancer detecting and treating tumor…”
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[18F]-Fluorodeoxyglucose-Positron Emission Tomography for the Assessment of Histopathologic Response and Prognosis After Completion of Neoadjuvant Chemoradiation in Esophageal Cancer by VALLBÖHMER, Daniel, HÖLSCHER, Arnulf H, DIETLEIN, Markus, BOLLSCHWEILER, Elfriede, BALDUS, Stephan E, MÖNIG, Stefan P, METZGER, Ralf, SCHICHA, Harald, SCHMIDT, Matthias

“…To evaluate the potential of [(18)F]-fluorodeoxyglucose-positron emission tomography (FDG-PET) after the completion of neoadjuvant chemoradiation for the…”
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Prognostic Significance of a New Grading System of Lymph Node Morphology After Neoadjuvant Radiochemotherapy for Esophageal Cancer by Bollschweiler, Elfriede, MD, PhD, Hölscher, Arnulf H., MD, Metzger, Ralf, MD, Besch, Sarah, MD, Mönig, Stefan P., MD, Baldus, Stephan E., MD, Drebber, Uta, MD

“…Background Along with primary tumor response, lymph node (LN) status after radiochemotherapy is one of the most important prognostic factors for advanced…”
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High Expression of HIF1a Is a Predictor of Clinical Outcome in Patients with Pancreatic Ductal Adenocarcinomas and Correlated to PDGFA, VEGF, and bFGF by Hoffmann, Andreas-Claudius, Mori, Ryutaro, Vallbohmer, Daniel, Brabender, Jan, Klein, Ellen, Drebber, Uta, Baldus, Stephan E., Cooc, Janine, Azuma, Mizutomo, Metzger, Ralf, Hoelscher, Arnulf H., Danenberg, Kathleen D., Prenzel, Klaus L, Danenberg, Peter V.

“…PURPOSE: Pancreatic cancer still has one of the worst prognoses in gastrointestinal cancers with a 5-year survival rate of 5%, making it necessary to find…”
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Epidermal Growth Factor Receptor and HER2-neu mRNA Expression in Non-Small Cell Lung Cancer Is Correlated with Survival by Brabender, J, Danenberg, K D, Metzger, R, Schneider, P M, Park, J, Salonga, D, Hölscher, A H, Danenberg, P V

“…The prognostic role of epidermal growth factor receptor (EGFR) and HER2-neu remains controversial in patients with non-small cell lung cancer (NSCLC). We…”
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Colorectal Tumors Responding to 5-Fluorouracil Have Low Gene Expression Levels of Dihydropyrimidine Dehydrogenase, Thymidylate Synthase, and Thymidine Phosphorylase by SALONGA, D, DANENBERG, K. D, DANENBERG, P. V, JOHNSON, M, METZGER, R, GROSHEN, S, TSAO-WEI, D. D, LENZ, H.-J, LEICHMAN, C. G, LEICHMAN, L, DIASIO, R. B

“…We had previously shown that high gene expressions (mRNA levels) of thymidylate synthase ( TS ; Leichman et al. , J. Clin. Oncol., 15: 3223–3229, 1997) and…”
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Influence of Neoadjuvant Chemoradiation on the Number and Size of Analyzed Lymph Nodes in Esophageal Cancer by Bollschweiler, Elfriede, Besch, Sarah, Drebber, Uta, Schröder, Wolfgang, Mönig, Stefan P., Vallböhmer, Daniel, Baldus, Stephan E., Metzger, Ralf, Hölscher, Arnulf H.

“…Background Studies have shown that along with primary tumor response, lymph node status after RTx/CTx is one of the most important prognostic factors for…”
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Prognostic Impact of Protein Overexpression of the Proto-oncogene PIM-1 in Gastric Cancer by Warnecke-Eberz, Ute, Bollschweiler, Elfriede, Drebber, Uta, Metzger, Ralf, Baldus, Stephan E, Hölscher, Arnulf H, Mönig, Stefan

“…Background: PIM kinases are mediators of cytokine signalling pathways in hematopoietic cells and contribute to the progression of certain types of leukemia and…”
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S100 family members and trypsinogens are predictors of distant metastasis and survival in early-stage non-small cell lung cancer by DIEDERICHS, Sven, BULK, Etmar, THOMAS, Michael, BERDEL, Wolfgang E, SERVE, Hubert, MÜLLER-TIDOW, Carsten, STEFFEN, Björn, PING JI, TICKENBROCK, Lara, LANG, Kerstin, ZÄNKER, Kurt S, METZGER, Ralf, SCHNEIDER, Paul M, GERKE, Volker

“…Distant metastasis is the predominant cause of death in early-stage non-small cell lung cancer (NSCLC). Currently, it is impossible to predict the occurrence…”
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Neoadjuvant chemoradiotherapy for esophageal cancer:Impact on extracapsular lymph node involvement by Metzger, Ralf

“…AIM:To assess the effects of neoadjuvant chemoradiotherapy(CRT) on the presence of extracapsular lymph node involvement(LNI) and its prognostic value in…”
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Identification of metastasis-associated receptor tyrosine kinases in non-small cell lung cancer by MÜLLER-TIDOW, Carsten, DIEDERICHS, Sven, BRANDTS, Christian H, BERDEL, Wolfgang E, SERVE, Hubert, BULK, Etmar, POHLE, Thorsten, STEFFEN, Björn, SCHWÄBLE, Joachim, PLEWKA, Sylvia, THOMAS, Michael, METZGER, Ralf, SCHNEIDER, Paul M

“…Development of distant metastasis after tumor resection is the leading cause of death in early-stage non-small cell lung cancer (NSCLC). Receptor tyrosine…”
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ERCC1: impact in multimodality treatment of upper gastrointestinal cancer by Metzger, Ralf, Bollschweiler, Elfriede, Hölscher, Arnulf H, Warnecke-Eberz, Ute

“…Platinum-based drugs and radiation are key elements of multimodality treatment in a wide variety of solid tumors and especially tumors of the upper…”
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pT2 Adenocarcinoma of the Esophagus: Early or Advanced Cancer? by Metzger, Ralf, MD, Lorenz, Dietmar, MD, Gockel, Ines, MD, Origer, Judith, MD, Plum, Patrick S., MD, Junginger, Theodor, MD, Drebber, Uta, MD, Hansen, Torsten, MD, Krümpelmann, Kristina, MD, Fisseler-Eckhoff, Annette, MD, Lang, Hauke, MD, Hölscher, Arnulf H., MD, Bollschweiler, Elfriede, MD, PhD

“…Background There is an increasing trend to include patients with esophageal carcinoma invading the muscularis propria (pT2) in neoadjuvant therapy regimens…”
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High Specificity of Quantitative Excision Repair Cross-Complementing 1 Messenger RNA Expression for Prediction of Minor Histopathological Response to Neoadjuvant Radiochemotherapy in Esophageal Cancer by WARNECKE-EBERZ, Ute, METZGER, Ralf, MUELLER, Rolf P, DANENBERG, Peter V, HOELSCHER, Arnulf H, SCHNEIDER, Paul M, MIYAZONO, Futoshi, BALDUS, Stephan E, NEISS, Susanne, BRABENDER, Jan, SCHAEFER, Hartmut, DOERFLER, Walter, BOLLSCHWEILER, Elfriede, DIENES, Hans P

“…Purpose: The excision repair cross-complementing 1 ( ERCC1 ) gene is coding for a nucleotide excision repair protein involved in the repair of radiation- and…”
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Roles of thymidylate synthase and dihydropyrimidine dehydrogenase expression in blood as predictors of response to multimodal therapy in esophageal cancer by Brabender, Jan, MD, Metzger, Ralf, MD, Vallböhmer, Daniel, MD, Ling, Frederike, MD, Neiss, Susanne, MTA, Bollschweiler, Elfriede, MD, Schneider, Paul M., MD, Hölscher, Arnulf H., MD, Grimminger, Peter P., MD

“…Background Thymidylate synthetase (TS) and dihydropyrimidine dehydrogenase (DPD) RNA expression in peripheral blood was examined as a noninvasive molecular…”
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Association of the GNAS1 T393C polymorphism with tumor stage and survival in gastric cancer by Alakus, Hakan, Mönig, Stefan P, Warnecke-Eberz, Ute, Alakus, Gül, Winde, Günther, Drebber, Uta, Schmitz, Klaus J, Schmid, Kurt W, Riemann, Kathrin, Siffert, Winfried, Bollschweiler, Elfriede, Hölscher, Arnulf H, Metzger, Ralf

“…AIM： To analyze the impact of the GNAS1 T393C polymorphism on prognosis and histopathology of gastric cancer. METHODS： Genomic DNA was extracted from…”
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High-Throughput Analysis of Genome-Wide Receptor Tyrosine Kinase Expression in Human Cancers Identifies Potential Novel Drug Targets by MÜLLER-TIDOW, Carsten, SCHWÄBLE, Joachim, SCHNEIDER, Paul M, BÜCHNER, Thomas, BRANDTS, Christian, BERDEL, Wolfgang E, SERVE, Hubert, STEFFEN, Björn, TIDOW, Nicola, BRANDT, Burkhardt, BECKER, Kerstin, SCHULZE-BAHR, Eric, HALFTER, Hartmut, VOGT, Ulf, METZGER, Ralf

“…Novel high-throughput analyses in molecular biology allow sensitive and rapid identification of disease-related genes and drug targets. We have used…”
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High Cyclooxygenase-2 Expression Following Neoadjuvant Radiochemotherapy Is Associated with Minor Histopathologic Response and Poor Prognosis in Esophageal Cancer by Xi, Huan, Baldus, Stephan E, Warnecke-Eberz, Ute, Brabender, Jan, Neiss, Susanne, Metzger, Ralf, Ling, Frederike C, Dienes, Hans P, Bollschweiler, Elfriede, Moenig, Stefan, Mueller, Rolf P, Hoelscher, Arnulf H, Schneider, Paul M

“…Purpose: High expression of cyclooxygenase-2 (COX-2) was shown to inhibit chemotherapy- and radiotherapy-induced apoptosis. We analyzed the association of…”
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XRCC1 Gene Polymorphism for Prediction of Response and Prognosis in the Multimodality Therapy of Patients with Locally Advanced Rectal Cancer by Grimminger, Peter P., M.D, Brabender, Jan, M.D, Warnecke-Eberz, Ute, Ph.D, Narumiya, Kosuke, M.D, Wandhöfer, Christoph, M.D, Drebber, Uta, M.D, Bollschweiler, Elfriede, M.D, Hölscher, Arnulf H., M.D., F.R.C.S., F.A.C.S, Metzger, Ralf, M.D, Vallböhmer, Daniel, M.D

“…Background Neoadjuvant treatment strategies have been developed to improve survival of patients with locally advanced rectal cancer. Since mainly patients with…”
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