Search Results - "MESSAOUDI, Samir"

Sulfinate derivatives: dual and versatile partners in organic synthesis by Aziz, Jessy, Messaoudi, Samir, Alami, Mouad, Hamze, Abdallah

“…Sulfinic acids and their salts have recently emerged as versatile coupling partners to efficiently access a wide variety of hetero- and carbocyclic compounds,…”
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Palladium‐Mediated Labeling of Nucleic Acids by Defrancq, Eric, Messaoudi, Samir

“…New applications of Pd‐catalyzed coupling reactions (Suzuki–Miyaura, Sonogashira, and Stille–Migita coupling) for post‐conjugation of nucleic acids have been…”
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Ni/Photoredox-Dual-Catalyzed Functionalization of 1‑Thiosugars by Zhu, Mingxiang, Dagousset, Guillaume, Alami, Mouad, Magnier, Emmanuel, Messaoudi, Samir

“…A general protocol for functionalization of glycosyl thiols has been reported. This protocol is based on a single-electron Ni/photoredox dual-catalyzed cross…”
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Room-Temperature Pd-Catalyzed Synthesis of 1‑(Hetero)aryl Selenoglycosides by Zhu, Mingxiang, Alami, Mouad, Messaoudi, Samir

“…A general protocol for functionalization of an anomeric selonate anion at room temperature has been reported. By using the PdG3 XantPhos catalyst, the…”
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Emerging Organometallic Methods for the Synthesis of C‐Branched (Hetero)aryl, Alkenyl, and Alkyl Glycosides: C−H Functionalization and Dual Photoredox Approaches by Ghouilem, Juba, Robichon, Morgane, Le Bideau, Franck, Ferry, Angélique, Messaoudi, Samir

“…Transition‐metal‐catalyzed C−H functionalization and photoredox nickel dual catalysis have emerged as innovative and powerful avenues for the synthesis of…”
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Transition-Metal-Catalyzed Direct C-H Alkenylation, Alkynylation, Benzylation, and Alkylation of (Hetero)arenes by Messaoudi, Samir, Brion, Jean-Daniel, Alami, Mouâd

“…Direct functionalization of (hetero)aromatic C–H bonds has recently emerged as a powerful tool for the functionalization of organic molecules. In the past…”
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Efficient Buchwald–Hartwig–Migita Cross‐Coupling for DNA Thioglycoconjugation by Probst, Nicolas, Lartia, Rémy, Théry, Océane, Alami, Mouâd, Defrancq, Eric, Messaoudi, Samir

“…An efficient method for the thioglycoconjugation of iodinated oligonucleotides by Buchwald–Hartwig–Migita cross‐coupling under mild conditions is reported. The…”
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Stereoretentive Palladium-Catalyzed Arylation, Alkenylation, and Alkynylation of 1-Thiosugars and Thiols Using Aminobiphenyl Palladacycle Precatalyst at Room Temperature by Bruneau, Alexandre, Roche, Maxime, Hamze, Abdallah, Brion, Jean-Daniel, Alami, Mouad, Messaoudi, Samir

“…A general and efficient protocol for the palladium‐catalyzed functionalization of mono‐ and polyglycosyl thiols by using the palladacycle precatalyst…”
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Nickel-Catalyzed Arylation, Alkenylation, and Alkynylation of Unprotected Thioglycosides at Room Temperature by Brachet, Etienne, Brion, Jean-Daniel, Alami, Mouad, Messaoudi, Samir

“…Unprotected thioglycosides were effective nucleophiles for Ni0‐catalyzed CS bond‐forming reaction with functionalized (hetero)aryl, alkenyl, and alkynyl…”
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Synthesis and Biological Activity of 3-(Heteroaryl)quinolin-2(1 H )-ones Bis-Heterocycles as Potential Inhibitors of the Protein Folding Machinery Hsp90 by Larghi, Enrique L, Bruneau, Alexandre, Sauvage, Félix, Alami, Mouad, Vergnaud-Gauduchon, Juliette, Messaoudi, Samir

“…In the context of our SAR study concerning 6BrCaQ analogues as C-terminal Hsp90 inhibitors, we designed and synthesized a novel series of…”
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Stereoretentive Copper-Catalyzed Directed Thioglycosylation of C(sp2)−H Bonds of Benzamides by Chabrier, Amélie, Bruneau, Alexandre, Benmahdjoub, Sara, Benmerad, Belkacem, Belaid, Sabrina, Brion, Jean-Daniel, Alami, Mouâd, Messaoudi, Samir

“…An efficient thioglycosylation of C(sp2)−H bonds with thiosugars has been established for the first time. Using only Cu(OAc)2⋅H2O as a catalyst and Ag2CO3 as…”
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Convergent Synthesis of N,S-bis Glycosylquinolin-2-ones via a Pd-G3-XantPhos Precatalyst Catalysis by Redjdal, Wafa, Ibrahim, Nada, Benmerad, Belkacem, Alami, Mouad, Messaoudi, Samir

“…Buchwald-Hartwig-Migita cross-coupling of 1-thiosugars with α- or β-3-iodo-N-glycosylquinolin-2-ones has been accomplished under mild and operationally simple…”
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Isocombretastatins A versus Combretastatins A: The Forgotten isoCA-4 Isomer as a Highly Promising Cytotoxic and Antitubulin Agent by Messaoudi, Samir, Tréguier, Bret, Hamze, Abdallah, Provot, Olivier, Peyrat, Jean-François, De Losada, Jordi Rodrigo, Liu, Jian-Miao, Bignon, Jérôme, Wdzieczak-Bakala, Joanna, Thoret, Sylviane, Dubois, Joëlle, Brion, Jean-Daniel, Alami, Mouâd

“…Herein is reported a convergent synthesis of isocombretastatins A, a novel class of potent antitubulin agents. These compounds having a 1,1-diarylethylene…”
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Conversion of 3‑Bromo‑2H‑coumarins to 3‑(Benzofuran-2-yl)‑2H‑coumarins under Palladium Catalysis: Synthesis and Photophysical Properties Study by Galvani, Gilles, Vardhan Reddy, K. Harsha, Beauvineau, Claire, Ghermani, NourEddine, Mahuteau-Betzer, Florence, Alami, Mouad, Messaoudi, Samir

“…An intriguing conversion of 3-bromo-2H-coumarins to 3-(benzofuran-2-yl)-2H-coumarins under palladium catalysis is reported. The process involves, from only one…”
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Palladium-Catalyzed Chemoselective and Biocompatible Functionalization of Cysteine-Containing Molecules at Room Temperature by Al-Shuaeeb, Riyadh Ahmed Atto, Kolodych, Sergii, Koniev, Oleksandr, Delacroix, Sébastien, Erb, Stéphane, Nicolaÿ, Stéphanie, Cintrat, Jean-Christophe, Brion, Jean-Daniel, Cianférani, Sarah, Alami, Mouâd, Wagner, Alain, Messaoudi, Samir

“…The third generation of aminobiphenyl palladacycle pre‐catalyst “G3‐Xantphos” enables functionalization of peptides containing cysteine in high yields. The…”
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Photoswitchable glycoligands targeting Pseudomonas aeruginosa LecA by Fan, Yu, El Rhaz, Ahmed, Maisonneuve, Stéphane, Gillon, Emilie, Fatthalla, Maha, Le Bideau, Franck, Laurent, Guillaume, Messaoudi, Samir, Imberty, Anne, Xie, Juan

“…Biofilm formation is one of main causes of bacterial antimicrobial resistance infections. It is known that the soluble lectins LecA and LecB, produced by ,…”
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Antitumor activity of nanoliposomes encapsulating the novobiocin analog 6BrCaQ in a triple-negative breast cancer model in mice by Sauvage, Félix, Fattal, Elias, Al-Shaer, Walhan, Denis, Stéphanie, Brotin, Emilie, Denoyelle, Christophe, Blanc-Fournier, Cécile, Toussaint, Balthazar, Messaoudi, Samir, Alami, Mouad, Barratt, Gillian, Vergnaud-Gauduchon, Juliette

“…In this study, we investigated the anticancer efficacy of pegylated liposomes containing 6BrCaQ, an hsp90 inhibitor derived from novobiocin. 6BrCaQ has been…”
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Stereoselective Palladium-Catalyzed Alkenylation and Alkynylation of Thioglycosides by Brachet, Etienne, Brion, Jean-Daniel, Alami, Mouad, Messaoudi, Samir

“…An efficient and unprecedented palladium‐catalyzed S‐glycosylation reaction of a range of alkenyl and alkynyl halides by using thiosugars as nucleophile…”
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Discovery of azaisoerianin derivatives as potential antitumors agents by Soussi, Mohamed Ali, Provot, Olivier, Bernadat, Guillaume, Bignon, Jérome, Wdzieczak-Bakala, Joanna, Desravines, Déborah, Dubois, Joëlle, Brion, Jean-Daniel, Messaoudi, Samir, Alami, Mouad

“…A series of N-methyl-diarylamines 2 was designed and synthesized as a novel class of CA-4 and isoCA-4 analogues. Compounds 2b and 2m showed excellent…”
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Palladium-catalyzed selective N-(hetero)arylation or N,N′-di(hetero)arylation of 1-aminoindoles by Messaoudi, Samir, Brion, Jean-Daniel, Alami, Mouâd

“…The selective synthesis of N-(hetero)aryl-1-aminoindoles 3 from the corresponding N-aminoindoles and (hetero)aryl halides using a catalyst combination of Pd…”
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