Search Results - "MESKER, W"
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Scoring the tumor-stroma ratio in colon cancer: procedure and recommendations
Published in Virchows Archiv : an international journal of pathology (01-10-2018)“…The tumor-stroma ratio (TSR) has been reported as a strong, independent prognostic parameter in colon cancer as well as in other epithelial cancer types, and…”
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The prognostic value of tumour–stroma ratio in primary breast cancer with special attention to triple-negative tumours: a review
Published in Breast cancer research and treatment (01-01-2019)“…Purpose There is a strong need to improve the prognostication of breast cancer patients in order to prevent over- and undertreatment, especially when…”
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The proportion of tumor-stroma as a strong prognosticator for stage II and III colon cancer patients: validation in the VICTOR trial
Published in Annals of oncology (01-01-2013)“…The intra-tumor stroma percentage in colon cancer (CC) patients has previously been reported by our group as a strong independent prognostic parameter…”
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Prognostic significance of the tumor-stroma ratio: validation study in node-negative premenopausal breast cancer patients from the EORTC perioperative chemotherapy (POP) trial (10854)
Published in Breast cancer research and treatment (01-06-2013)“…The tumor-stroma ratio has previously been shown to be prognostic for patients with invasive breast cancer. We present a validation study to assess the…”
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Interaction with colon cancer cells hyperactivates TGF-β signaling in cancer-associated fibroblasts
Published in Oncogene (02-01-2014)“…The interaction between epithelial cancer cells and cancer-associated fibroblasts (CAFs) has a major role in cancer progression and eventually in metastasis…”
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The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC
Published in British journal of cancer (06-01-2015)“…Background: Constitutive Wnt activation is essential for colorectal cancer (CRC) initiation but also underlies the cancer stem cell phenotype, metastasis and…”
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Prognostic value of tumor–stroma ratio combined with the immune status of tumors in invasive breast carcinoma
Published in Breast cancer research and treatment (01-04-2018)“…Purpose Complex interactions occur between cancer cells and cells in the tumor microenvironment. In this study, the prognostic value of the interplay between…”
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Outcomes following pancreatic surgery using three different thromboprophylaxis regimens
Published in British journal of surgery (01-05-2019)“…Background Postpancreatectomy haemorrhage (PPH) and venous thromboembolism (VTE) are serious complications following pancreatic surgery. The aim was to assess…”
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Reliability of core needle biopsy for determining ER and HER2 status in breast cancer
Published in Annals of oncology (01-04-2013)“…Several studies have assessed the concordance of estrogen receptor (ER) and human epidermal growth factor receptor 2 (HER2) status between core needle biopsy…”
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The prognostic role of TGF-β signaling pathway in breast cancer patients
Published in Annals of oncology (01-02-2013)“…The transforming growth factor-β (TGF-β) pathway has dual effects on tumor growth. Seemingly, discordant results have been published on the relation between…”
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Association Between the Most Frequent Complications After Surgery for Stage I–III Colon Cancer and Short-Term Survival, Long-Term Survival, and Recurrences
Published in Annals of surgical oncology (01-09-2016)“…Background The purpose of this study was to identify the ten most frequent complications after surgery for stage I–III colon cancer and to assess the…”
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A high tumour-stroma ratio (TSR) in colon tumours and its metastatic lymph nodes predicts poor cancer-free survival and chemo resistance
Published in Clinical & translational oncology (01-06-2022)“…Purpose Despite known high-risk features, accurate identification of patients at high risk of cancer recurrence in colon cancer remains a challenge. As tumour…”
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Longitudinal changes of serum protein N-Glycan levels for earlier detection of pancreatic cancer in high-risk individuals
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01-05-2022)“…Surveillance of individuals at risk of developing pancreatic ductal adenocarcinoma (PDAC) has the potential to improve survival, yet early detection based on…”
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Quality assessment of estrogen receptor and progesterone receptor testing in breast cancer using a tissue microarray-based approach
Published in Breast cancer research and treatment (01-07-2015)“…Assessing hormone receptor status is an essential part of the breast cancer diagnosis, as this biomarker greatly predicts response to hormonal treatment…”
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Quantitative assessment of lymph vascular space invasion (LVSI) provides important prognostic information in node-negative breast cancer
Published in Annals of oncology (01-12-2013)“…Some studies investigating the prognostic value of lymph vascular space invasion (LVSI) have shown an association between LVSI and disease-free survival…”
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Comment on: The prognostic significance of tumour-stroma ratio in oestrogen receptor-positive breast cancer
Published in British journal of cancer (26-05-2015)Get full text
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Results from the UNITED study: a multicenter study validating the prognostic effect of the tumor–stroma ratio in colon cancer
Published in ESMO open (01-04-2024)“…The TNM (tumor–node–metastasis) Evaluation Committee of Union for International Cancer Control (UICC) and College of American Pathologists (CAP) recommended to…”
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The value of tumor-stroma ratio as predictor of pathologic response after neoadjuvant chemoradiotherapy in esophageal cancer
Published in Clinical and translational radiation oncology (01-01-2020)“…•Scoring the tumor-stroma ratio is a simple and reproducible method.•Tumor-stroma ratio and response to neoadjuvant chemoradiotherapy are…”
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