Search Results - "MESHKI, John"

Neurokinin 1 Receptor Mediates Membrane Blebbing in HEK293 Cells through a Rho/Rho-associated Coiled-coil Kinase-dependent Mechanism by Meshki, John, Douglas, Steven D., Lai, Jian-Ping, Schwartz, Lynnae, Kilpatrick, Laurie E., Tuluc, Florin

“…We have investigated the effect of neurokinin 1 receptor (NK1R) agonists on HEK293 cells transfected with the NK1R receptor. The NK1R receptor mediates…”
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Substance P induces rapid and transient membrane blebbing in U373MG cells in a p21-activated kinase-dependent manner by Meshki, John, Douglas, Steven D, Hu, Mingyue, Leeman, Susan E, Tuluc, Florin

“…U373MG astrocytoma cells endogenously express the full-length neurokinin 1 receptor (NK1R). Substance P (SP), the natural ligand for NK1R, triggers rapid and…”
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Neurokinin 1 receptor mediates membrane blebbing and sheer stress-induced microparticle formation in HEK293 cells by Chen, Panpan, Douglas, Steven D, Meshki, John, Tuluc, Florin

“…Cell-derived microparticles participate in intercellular communication similar to the classical messenger systems of small and macro-molecules that bind to…”
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Molecular mechanism of nucleotide-induced primary granule release in human neutrophils: role for the P2Y2 receptor by Meshki, John, Tuluc, Florin, Bredetean, Ovidiu, Ding, Zhongren, Kunapuli, Satya P

“…Nucleotides are released during vascular injury from activated platelets and broken cells, which could stimulate human neutrophils. In this study, we…”
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Molecular mechanisms of protein kinase C-induced apoptosis in prostate cancer cells by Gonzalez-Guerrico, Anatilde M, Meshki, John, Xiao, Liqing, Benavides, Fernando, Conti, Claudio J, Kazanietz, Marcelo G

“…Protein kinase C (PKC) isozymes, a family of serine-threonine kinases, are important regulators of cell proliferation and malignant transformation. Phorbol…”
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Substance P–mediated chemokine production promotes monocyte migration by Spitsin, Sergei, Meshki, John, Winters, Angela, Tuluc, Florin, Benton, Tami D., Douglas, Steven D.

“…Exposure of human PBMC to substance P results in production of chemokines, including MCP‐1, which increases migration of human monocytes. The neuropeptide SP…”
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HIV infection of macrophages is enhanced in the presence of increased expression of CD163 induced by substance P by Tuluc, Florin, Meshki, John, Spitsin, Sergei, Douglas, Steven D.

“…HIV infection in macrophages is enhanced by substance P through a mechanism dependent on the haptoglobinhemoglobin scavenger receptor CD163. Activation of NK1R…”
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Regulation of Prostate Cancer Cell Survival by Protein Kinase Cε Involves Bad Phosphorylation and Modulation of the TNFα/JNK Pathway by Meshki, John, Caino, M. Cecilia, von Burstin, Vivian A, Griner, Erin, Kazanietz, Marcelo G

“…Protein kinase Cε (PKCε), a diacyglycerol- and phorbol ester-responsive serine-threonine kinase, has been implicated in mitogenic and survival control, and it…”
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Hallmarks for senescence in carcinogenesis: novel signaling players by Caino, M. Cecilia, Meshki, John, Kazanietz, Marcelo G

“…Cellular senescence is a potent anti-cancer mechanism controlled by tumor suppressor genes, particularly p53 and pRb, which is characterized by the…”
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Anti-HIV-1 activity of the neurokinin-1 receptor antagonist aprepitant and synergistic interactions with other antiretrovirals by MANAK, Mark M, MOSHKOFF, Dmitry A, NGUYEN, LequanT, MESHKI, John, TEBAS, Pablo, TULUC, Florin, DOUGLAS, Steven D

“…Neurokinin-1 receptor (NK1R) antagonists interfere with binding of neuropeptide substance P to NK1R and exhibit novel anti-HIV-1 activities. Since NK1R…”
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Regulation of Prostate Cancer Cell Survival by Protein Kinase C∈ Involves Bad Phosphorylation and Modulation of the TNFα/JNK Pathway by Meshki, John, Caino, M. Cecilia, von Burstin, Vivian A., Griner, Erin, Kazanietz, Marcelo G.

“…Protein kinase C∈ (PKC∈), a diacyglycerol- and phorbol ester-responsive serine-threonine kinase, has been implicated in mitogenic and survival control, and it…”
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Substance P enhances HIV-1 infection in human fetal brain cell cultures expressing full-length neurokinin-1 receptor by Schwartz, Lynnae, Spitsin, Sergei V., Meshki, John, Tuluc, Florin, Douglas, Steven D., Wolfe, John H.

“…The associations between the neurokinin-1 receptor (NK-1R), substance P (SP), and HIV-1 were investigated in neurosphere-derived cultures of…”
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Analog of somatostatin vapreotide exhibits biological effects in vitro via interaction with neurokinin-1 receptor by Spitsin, Sergei, Tuluc, Florin, Meshki, John, Ping Lai, Jian, Tustin Iii, Richard, Douglas, Steven D

“…Vapreotide, a synthetic analog of somatostatin, has analgesic activity most likely mediated through the blockade of neurokinin-1 receptor (NK1R), the substance…”
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Neurokinin 1 Receptor Mediates Membrane Blebbing in HEK293 Cells through a Rho/Rho-associated Coiled-coil Kinase-dependent MechanismS by Meshki, John, Douglas, Steven D., Lai, Jian-Ping, Schwartz, Lynnae, Kilpatrick, Laurie E., Tuluc, Florin

“…We have investigated the effect of neurokinin 1 receptor (NK1R) agonists on HEK293 cells transfected with the NK1R receptor. The NK1R receptor mediates…”
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PII: S1567-5769(05)00245-6 by Tuluc, Florin, Meshki, John, Kunapuli, Satya P.

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Reply to letter to the editor by Tuluc, Florin, Meshki, John, Kunapuli, Satya P.

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Primary granule release from human neutrophils is potentiated by soluble fibrinogen through a mechanism depending on multiple intracellular signaling pathways by Tuluc, Florin, Garcia, Analia, Bredetean, Ovidiu, Meshki, John, Kunapuli, Satya P

“…N-Formyl-methionyl-leucyl-phenylalanine (fMLP) is a potent activator of neutrophil degranulation. The intracellular signaling mechanisms involved in the…”
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Membrane lipid microdomains differentially regulate intracellular signaling events in human neutrophils by Tuluc, Florin, Meshki, John, Kunapuli, Satya P.

“…The integrity of lipid microdomains is disrupted after cell treatment with cholesterol-depleting reagents, such as methyl-β-cyclodextrin (MCD). We investigated…”
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Extracellular Nucleotide UTP Regulate Lipopolisaccharide-Induced Cytokine Production in Human Neutrophils by Garcia, Analia E., Tuluc, Florin, Meshki, John, Bredetean, Ovidiu, Kunapuli, Satya P.

“…Extracellular nucleotides can function as paracrine and autocrine mediators that signal through P2Y nucleotide receptors. Human polymorphonuclear (PMN) cells…”
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Signaling pathways downstream of P2 receptors in human neutrophils by Meshki, John, Tuluc, Florin, Bredetean, Ovidiu, Garcia, Analia, Kunapuli, Satya P

“…Extracellular nucleotides stimulate human neutrophils by activating the purinergic P2Y(2) receptor. However, it is not completely understood which types of G…”
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