Search Results - "MERTELSMANN, R. H"

Haploidentical 'megadose' stem cell transplantation in acute leukemia: Recommendations for a protocol agreed upon at the perugia and chicago meetings by CHAMPLIN, R, HESDORFFER, C, LOWENBERG, B, MARTELLI, M. F, MERTELSMANN, R. H, REISNER, Y, SCHMITZ, N

“…Leukemia (2002) 16, 427-428. DOI: 10.1038/sj/leu/2402386…”
Get full text

Participation of the cytokines interleukin 6, tumor necrosis factor-alpha, and interleukin 1-beta secreted by acute myelogenous leukemia blasts in autocrine and paracrine leukemia growth control by OSTER, W, CICCO, N. A, KLEIN, H, HIRANO, T, KISHIMOTO, T, LINDEMANN, A, MERTELSMANN, R. H, HERRMANN, F

“…Autonomous in vitro growth of myeloid leukemic colony-forming cells may in part result from autocrine production of colony-stimulating factors (CSF). Some…”
Get full text

Granulocyte/macrophage colony-stimulating factor induces interleukin 1 production by human polymorphonuclear neutrophils by Lindemann, A, Riedel, D, Oster, W, Meuer, SC, Blohm, D, Mertelsmann, RH, Herrmann, F

“…The purpose of this study was to determine whether human polymorphonuclear neutrophils (PMN), which share a common cell lineage with macrophages, could produce…”
Get full text

Interleukin 1 stimulates T lymphocytes to produce granulocyte-monocyte colony-stimulating factor by HERRMANN, F, OSTER, W, MEUER, S. C, LINDEMANN, A, MERTELSMANN, R. H

“…T lymphocytes are thought to cooperatively interact with monocytes to produce colony-stimulating factors (CSF). However, little is known about…”
Get full text

Functional consequences of monocyte IL-2 receptor expression. Induction of IL-1 beta secretion by IFN gamma and IL-2 by Herrmann, F, Cannistra, SA, Lindemann, A, Blohm, D, Rambaldi, A, Mertelsmann, RH, Griffin, JD

“…The generation of an immune response involves the interaction of monocytes and T cells, but the events which regulate this interaction are not well understood…”
Get full text

Interleukin 2 and interferon alpha-2a do not improve anti-tumour activity of 5-fluorouracil in advanced colorectal cancer by GOEY, S. H, GRATAMA, J. W, PRIMROSE, J. N, WARD, U, MERTELSMANN, R. H, OSTERWALDER, B, VERWEIJ, J, STOTER, G

“…Treatment using a combination of 5-fluorouracil (5-FU), interferon-alpha (IFN alpha-2a) and interleukin 2 (IL-2) has been shown to mediate disease regression…”
Get full text

Interferon-gamma interrupts autocrine growth mediated by endogenous interleukin-6 in renal-cell carcinoma by Gruss, H J, Brach, M A, Mertelsmann, R H, Herrmann, F

“…Cells of the renal-cell carcinoma line ACHN constitutively produce IL-6, express the IL-6 receptor and use IL-6 in an autocrine fashion to augment their…”
Get more information

Regulation of gene expression of macrophage-colony stimulating factor in human fibroblasts by the acute phase response mediators interleukin (IL)-1β, tumor necrosis factor-α and IL-6 by Mantovani, Luisa, Henschler, Reinhard, Brach, Marion A., Mertelsmann, Roland H., Herrmann, Friedhelm

“…Fibroblasts constitute a major element of the bone marrow stroma. They play a pivotal role in blood cell development by providing the scaffolding required for…”
Get full text

Synergistic effect of recombinant human leukemia inhibitory factor (LIF) and 1-beta-D-arabinofuranosylcytosine (Ara-C) on proto-oncogene expression and induction of differentiation in human U 937 cells by Brach, M A, Riedel, D, Mertelsmann, R H, Herrmann, F

“…The in vitro action of recombinant human leukemia inhibitory factor (LIF) and 1-beta-D arabinofuranosylcytosine (ara-C) was studied on the human leukemia cell…”
Get more information

Functional Expression of c-kit by Acute Myelogenous Leukemia Blasts Is Enhanced by Tumor Necrosis Factor-α Through Posttranscriptional mRNA Stabilization by a Labile Protein by Brach, Marion A., Bühring, Hans-Jörg, Gruβ, Hans-Jürgen, Ashman, Leonie K., Ludwig, Wolf-Dieter, Mertelsmann, Roland H., Herrmann, Friedhelm

“…The c-kit proto-oncogene encodes a transmembrane glycoprotein identical to the receptor for the recently cloned stem cell factor (SCF). The present study…”
Get full text

Synthesis of granulocyte colony-stimulating factor and its requirement for terminal divisions in chronic myelogenous leukemia by KLEIN, H, BECHER, R, LUÊBBERT, M, OSTER, W, SCHLEIERMACHER, E, BRACH, M. A, SOUZA, L, LINDEMANN, A, MERTELSMANN, R. H, HERRMANN, F

“…In this paper we demonstrate that maturing neoplastic cells from patients with chronic myelogenous leukemia (CML) constitutively produce G-CSF and are also…”
Get full text

Medullary histiocytosis following treatment of severe aplastic anemia with recombinant human interleukin-3 in combination with antilymphocyte globulin, cyclosporin A, and methylprednisolone by HERRMANN, F, LINDEMANN, A, LANGE, W, KOCHLING, G, RAGHAVACHAR, A, SCHREZENMEIER, H, FRICKHOFEN, N, MERTELSMANN, R. H

“…This case report describes the clinical use of recombinant human interleukin-3 as adjunct to immunosuppressive therapy with antilymphocyte globulin,…”
Get full text

Human B cell-inducing factor(s) for production of IgM, IgG and IgA: independence from IL 2 by Ralph, P, Welte, K, Levi, E, Nakoinz, I, Litcofsky, PB, Mertelsmann, RH, Moore, MA

“…Human peripheral blood B cells are stimulated into proliferation by killed Staphylococcus aureus bacteria strain Cowan I (Sac). T lymphocytes in the presence…”
Get full text

Differential regulation of interleukin-6 expression in human fibroblasts by tumor necrosis factor-α and lymphotoxin by Mantovani, Luisa, Henschler, Reinhard, Brach, Marion A., Wieser, Raimund, Lübbert, Michael, Lindemann, Albrecht, Mertelsmann, Roland H., Herrmann, Friedhelm

“…The treatment of human diploid fibroblasts with tumor necrosis factor (TNP)-α and with lymphotoxin (LT) is associated with induction of interleuk-in-6 (IL-6)…”
Get full text

Hematopoietins in combination with 1-beta-D-arabinofuranosylcytosine: a possible strategy for improved treatment of myeloid disorders by Brach, M A, Mertelsmann, R H, Herrmann, F

“…Inhibitors of DNA synthesis, such as 1-beta-D-arabinofuranosylcytosine, have been proven useful in the management of acute myelogenous leukemia. Despite…”
Get more information

Rescue of anti-influenza A virus cytotoxic T-lymphocyte responses in chemotherapy-suppressed mice by MERLUZI, V. J, WELTE, K, MERTELSMANN, R. H, SOUZA, L, BOONE, T, LAST-BARNEY, K

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Prognostic Significance of Receptors for the Third Component of Complement and Heavy Chain Phenotype in Diffuse B-Cell Lymphomas by Gold, Edward J., Mertelsmann, Roland H., Filippa, Daniel A., Szatrowski, Ted H., Koziner, Benjamin, Clarkson, Bayard

“…As part of a larger study to determine the prognostic significance of cell marker phenotype in diffuse lymphomas, 51 patients with monoclonal B-cell lymphoma…”
Get full text

Raf-1 is a necessary component of the mitogenic response of the human megakaryoblastic leukemia cell line MO7 to human stem cell factor, granulocyte-macrophage colony-stimulating factor, interleukin 3, and interleukin 9 by BRENNSCHEIDT, U, RIEDEL, D, KÖLCH, W, BONIFER, R, BRACH, M. A, AHLERS, A, MERTELSMANN, R. H, HERRMANN, F

“…We have examined the role of Raf-1 in the mitogenic response of the factor-deprived human megakaryoblastic leukemia cell line MO7 to recombinant human…”
Get full text

Expression of cytokine genes, cytokine receptor genes, and transcription factors in cultured hodgkin and Reed-Sternberg cells by GRUSS, H.-J, BRACH, M. A, DREXLER, H.-G, BONIFER, R, MERELSMANN, R. H, HERRMANN, F

“…In the present study, we show by Northern blot analysis and enzyme linked immunosorbent assay that the Hodgkin's disease (HD)-derived cell lines HDLM-2 and…”
Get full text

Mechanisms of p53 alteration in acute leukemias by Schottelius, A, Brennscheidt, U, Ludwig, W D, Mertelsmann, R H, Herrmann, F, Lübbert, M

“…Disruption of normal p53 expression is the most frequent genetic change occurring in various human solid tumors; it is mostly due to sequence alterations of…”
Get more information