Search Results - "MERLINO, Giuseppe"
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Two-Stage vs Single-Stage Thermophilic Anaerobic Digestion: Comparison of Energy Production and Biodegradation Efficiencies
Published in Environmental science & technology (07-08-2012)“…Two-stage anaerobic digestion (AD) for integrated biohydrogen and biomethane production from organic materials has been reported to promise higher process…”
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Consistent bacterial selection by date palm root system across heterogeneous desert oasis agroecosystems
Published in Scientific reports (11-03-2019)“…Highly productive conventional agroecosystems are spatially embedded in resource-homogeneous systems and count on generally nutrient-rich soils. On the…”
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Rhizosheath microbial community assembly of sympatric desert speargrasses is independent of the plant host
Published in Microbiome (04-12-2018)“…The rhizosheath-root system is an adaptive trait of sandy-desert speargrasses in response to unfavourable moisture and nutritional conditions. Under the…”
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4
Electricity generation using white and red wine lees in air cathode microbial fuel cells
Published in Journal of power sources (15-01-2015)“…Microbial fuel cell (MFC) is a useful biotechnology to produce electrical energy from different organic substrates. This work reports for the first time…”
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Using olive mill wastewater to improve performance in producing electricity from domestic wastewater by using single-chamber microbial fuel cell
Published in Bioresource technology (01-11-2013)“…•Olive mill wastewater (OMW) represents a problem for its disposal and treatment.•Single-chamber MFC was used to produce electricity from OMW and wastewater…”
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Fine-scale metabolic discontinuity in a stratified prokaryote microbiome of a Red Sea deep halocline
Published in The ISME Journal (01-08-2021)“…Deep-sea hypersaline anoxic basins are polyextreme environments in the ocean’s interior characterized by the high density of brines that prevents mixing with…”
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Insights Into the Cultivable Bacterial Fraction of Sediments From the Red Sea Mangroves and Physiological, Chemotaxonomic, and Genomic Characterization of Mangrovibacillus cuniculi gen. nov., sp. nov., a Novel Member of the Bacillaceae Family
Published in Frontiers in microbiology (18-02-2022)“…Mangrove forests are dynamic and productive ecosystems rich in microbial diversity; it has been estimated that microbial cells in the mangrove sediments…”
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Model‐based prediction of effective target exposure for MEN1611 in combination with trastuzumab in HER2‐positive advanced or metastatic breast cancer patients
Published in CPT: pharmacometrics and systems pharmacology (01-11-2023)“…MEN1611 is a novel orally bioavailable PI3K inhibitor currently in clinical development for patients with HER2‐positive (HER2+) PI3KCA mutated…”
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Discovery of Afifi, the shallowest and southernmost brine pool reported in the Red Sea
Published in Scientific reports (22-01-2020)“…The previously uncharted Afifi brine pool was discovered in the eastern shelf of the southern Red Sea. It is the shallowest brine basin yet reported in the Red…”
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The identification of the new species Nitratireductor thuwali sp. nov. reveals the untapped diversity of hydrocarbon-degrading culturable bacteria from the arid mangrove sediments of the Red Sea
Published in Frontiers in microbiology (02-05-2023)“…The geological isolation, lack of freshwater inputs and specific internal water circulations make the Red Sea one of the most extreme-and unique-oceans on the…”
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Targeting CD205 with the antibody drug conjugate MEN1309/OBT076 is an active new therapeutic strategy in lymphoma models
Published in Haematologica (Roma) (01-11-2020)“…Antibody drug conjugates represent an important class of anti-cancer drugs in both solid tumors and hematological cancers. Here, we report preclinical data on…”
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Bioturbation Intensity Modifies the Sediment Microbiome and Biochemistry and Supports Plant Growth in an Arid Mangrove System
Published in Microbiology spectrum (01-06-2022)“…In intertidal systems, the type and role of interactions among sediment microorganisms, animals, plants and abiotic factors are complex and not well…”
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Comparative Magnetic Resonance Imaging and Histopathological Correlates in Two SOD1 Transgenic Mouse Models of Amyotrophic Lateral Sclerosis
Published in PloS one (01-07-2015)“…Amyotrophic Lateral Sclerosis (ALS) is a progressive and fatal disease due to motoneuron degeneration. Magnetic resonance imaging (MRI) is becoming a promising…”
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The activity of a PI3K δ-sparing inhibitor, MEN1611, in non-small cell lung cancer cells with constitutive activation of the PI3K/AKT/mTOR pathway
Published in Frontiers in oncology (14-11-2023)“…Background Lung cancer remains the leading cause of cancer-related death worldwide. Targeted therapies with tyrosine kinase inhibitors (TKIs) result in…”
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Tumor Growth in the High Frequency Medulloblastoma Mouse Model Ptch1+/−/Tis21KO Has a Specific Activation Signature of the PI3K/AKT/mTOR Pathway and Is Counteracted by the PI3K Inhibitor MEN1611
Published in Frontiers in oncology (30-07-2021)“…We have previously generated a mouse model ( Ptch1 +/− /Tis21 KO ), which displays high frequency spontaneous medulloblastoma, a pediatric tumor of the…”
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MEN1309/OBT076, a First-In-Class Antibody-Drug Conjugate Targeting CD205 in Solid Tumors
Published in Molecular cancer therapeutics (01-09-2019)“…CD205 is a type I transmembrane glycoprotein and is a member of the C-type lectin receptor family. Analysis by mass spectrometry revealed that CD205 was…”
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Autogenous Regulation of Escherichia coli Polynucleotide Phosphorylase Expression Revisited
Published in Journal of Bacteriology (01-03-2009)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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In-depth characterization of breast cancer tumor-promoting cell transcriptome by RNA sequencing and microarrays
Published in Oncotarget (05-01-2016)“…Numerous studies have reported the existence of tumor-promoting cells (TPC) with self-renewal potential and a relevant role in drug resistance. However,…”
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Tumor-extracellular matrix interactions: Identification of tools associated with breast cancer progression
Published in Seminars in cancer biology (01-12-2015)“…Abstract Several evidences support the concept that cancer development and progression are not entirely cancer cell-autonomous processes, but may be…”
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Complexity in the tumour microenvironment: Cancer associated fibroblast gene expression patterns identify both common and unique features of tumour-stroma crosstalk across cancer types
Published in Seminars in cancer biology (01-12-2015)“…Abstract Cancer is a complex disease, driven by the accumulation of several somatic aberrations but fostered by a two-way interaction between tumour cells and…”
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