Search Results - "MEREDITH, P. A"

Do inhibitors of angiotensin-I-converting enzyme protect against risk of cancer? by Lever, Anthony F, Hole, David J, Gillis, Charles R, McCallum, Iain R, McInnes, Gordon T, MacKinnon, Pauline L, Meredith, Peter A, Murray, Lilian S, Reid, John L, Robertson, James WK

“…Previous studies have reported an increased risk of cancer with calcium-channel blockers in man. Other work in animals suggests that inhibitors of…”
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Comments on systematic review of clinical- and cost-effectiveness of candesartan and losartan in hypertension and heart failure by Meredith, P A, Jarvis, S C

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Comparison of the efficacy of candesartan and losartan: a meta-analysis of trials in the treatment of hypertension by Meredith, P A, Murray, L S, McInnes, G T

“…Informed by the findings from prospective observational studies and randomized outcome trials, guidelines for the management of hypertension acknowledge that…”
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Preferential benefits of nifedipine GITS in systolic hypertension and in combination with RAS blockade: further analysis of the 'ACTION' database in patients with angina by Elliott, H L, Meredith, P A

“…A retrospective analysis of the database from A Coronary Disease Trial Investigating Outcome with Nifedipine (ACTION) evaluated the effectiveness of nifedipine…”
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ACE (I/D) genotype as a predictor of the magnitude and duration of the response to an ACE inhibitor drug (Enalaprilat) in humans by UEDA, S, MEREDITH, P. A, MORTON, J. J, CONNELL, J. M. C, ELLIOTT, H. L

“…We have investigated the possible effects of contrasting ACE (I/D) genotypes on the responses to the ACE inhibitor enalaprilat in normotensive men. Subjects…”
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Clinical pharmacokinetics of amlodipine by MEREDITH, P. A, ELLIOTT, H. L

“…Amlodipine is a dihydropyridine calcium antagonist drug with distinctive pharmacokinetic characteristics which appear to be attributable to a high degree of…”
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Generic drugs : Therapeutic equivalence by MEREDITH, P. A

“…For economic reasons, the use of generic substitution is increasingly being supported by health authorities. Potentially, this may be problematic for drugs…”
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Therapeutic implications of drug ‘holidays’ by Meredith, P A

“…While a patient may appear to be fully compliant with respect to quantity of medication ingested, the timing of doses can vary considerably. This may introduce…”
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Blood pressure variability and its implications for antihypertensive therapy by Meredith, P A, Perloff, D, Mancia, G, Pickering, T

“…Although it is clear that antihypertensive treatment is beneficial in reducing stroke morbidity and mortality, the results of the major outcome studies show…”
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Trough/peak ratios for antihypertensive agents : the issues in perspective by MEREDITH, P. A

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Importance of trough : peak ratios in treatment of blood pressure in post-myocardial infarction and heart failure settings by MEREDITH, P. A

“…Hypertension increases the risk of reinfarction and sudden death in the post-myocardial infarction patient, and the same also applies to the co-existing left…”
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Thrombosis of internal jugular vein associated with acute parotitis by Hadjihannas, E, Kesse, K W, d'E Meredith, A P

“…We report a case of thrombosis of the right internal jugular vein associated with right parotitis. The literature is briefly reviewed…”
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Cancer risk of hypertensive patients taking calcium antagonists by Hole, David J, Gillis, Charles R, McCallum, Iain R, McInnes, Gordon T, MacKinnon, Pauline L, Meredith, Peter A, Murray, Lilian S, Robertson, James W.K, Lever, Anthony F

“…OBJECTIVETo measure rates of incident and fatal cancer in hypertensive patients taking calcium antagonists and to compare these with rates in three control…”
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Differential effects of a missed dose of trandolapril and enalapril on blood pressure control in hypertensive patients by Vaur, L, Dutrey-Dupagne, C, Boussac, J, Genes, N, Bouvier d'Yvoire, M, Elkik, F, Meredith, P A

“…A double blind randomised comparison of two angiotensin-converting enzyme (ACE) inhibitors was made in a study in which ambulatory blood pressure was monitored…”
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The Importance of Sustained Blood Pressure Control by Meredith, Peter A

“…The case for antihypertensive drug regimens that produce consistent 24-h blood pressure control has largely been founded upon a series of epidemiological…”
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Dose-Ranging Study of the Angiotensin II Receptor Antagonist Irbesartan (SR 47436/BMS-186295) on Blood Pressure and Neurohormonal Effects in Salt-Deplete Men by McIntyre, M, MacFadyen, R J, Meredith, P A, Brouard, R, Reid, J L

“…SUMMARYWe characterised the blood pressure (BP) and hormonal responses to the oral angiotensin II (Ang II) receptor antagonist irbesartan (SR47436/BMS-186295)…”
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Evaluation of an Antihypertensive Therapy Utilising Meta-analysis of a Clinical Trial Database by Meredith, Peter A

“…The emphasis on evidence-based medicine and the use of safe, cost-effective therapeutic strategies demands that management decisions be based upon evidence…”
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A comparative assessment of amlodipine and felodipine ER : pharmacokinetic and pharmacodynamic indices by BAINBRIDGE, A. D, HERLIHY, O, MEREDITH, P. A, ELLIOTT, H. L

“…This study investigated potential therapeutic differences between Amlodipine 5 mg and Felodipine ER 10 mg in 12 normotensive/borderline hypertensive subjects…”
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Trough: peak ratio: clinically useful or practically irrelevant? by Elliott, H L, Meredith, P A

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Clinical Outcomes According to Baseline Blood Pressure in Patients With a Low Ejection Fraction in the CHARM (Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity) Program by Meredith, Peter A., PhD, Östergren, Jan, MD, Anand, Inder, MD, Puu, Margareta, PhD, Solomon, Scott D., MD, Michelson, Eric L., MD, Olofsson, Bertil, PhD, Granger, Christopher B., MD, Yusuf, Salim, MB, BS, DPhil, Swedberg, Karl, MD, PhD, Pfeffer, Marc A., MD, PhD, McMurray, John J.V., MD

“…Objectives This study sought to investigate the efficacy and tolerability of candesartan, according to baseline blood pressure (BP), in the 4,576 patients with…”
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