Search Results - "MERCURIO, M"

VEGF/Neuropilin Signaling in Cancer Stem Cells by Mercurio, Arthur M

“…The function of vascular endothelial growth factor (VEGF) in cancer extends beyond angiogenesis and vascular permeability. Specifically, VEGF-mediated…”
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Prominin2 Drives Ferroptosis Resistance by Stimulating Iron Export by Brown, Caitlin W., Amante, John J., Chhoy, Peter, Elaimy, Ameer L., Liu, Haibo, Zhu, Lihua Julie, Baer, Christina E., Dixon, Scott J., Mercurio, Arthur M.

“…Ferroptosis, regulated cell death characterized by the iron-dependent accumulation of lethal lipid reactive oxygen species, contributes to tissue homeostasis…”
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Convergence of VEGF and YAP/TAZ signaling: Implications for angiogenesis and cancer biology by Elaimy, Ameer L, Mercurio, Arthur M

“…Vascular endothelial growth factor (VEGF) stimulates endothelial cells to promote both developmental and pathological angiogenesis. VEGF also directly affects…”
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The α6β4 integrin promotes resistance to ferroptosis by Brown, Caitlin W, Amante, John J, Goel, Hira Lal, Mercurio, Arthur M

“…Increases in lipid peroxidation can cause ferroptosis, a form of cell death triggered by inhibition of glutathione peroxidase 4 (GPX4), which catalyzes the…”
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CD44 splice isoform switching determines breast cancer stem cell state by Zhang, Honghong, Brown, Rhonda L, Wei, Yong, Zhao, Pu, Liu, Sali, Liu, Xuan, Deng, Yu, Hu, Xiaohui, Zhang, Jing, Gao, Xin D, Kang, Yibin, Mercurio, Arthur M, Goel, Hira Lal, Cheng, Chonghui

“…Although changes in alternative splicing have been observed in cancer, their functional contributions still remain largely unclear. Here we report that splice…”
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THE APPLICABILITY OF LOW-COST MULTI-FREQUENCY MULTI-GNSS RECEIVERS FOR GEODETIC CONTROL SURVEYING by Mercurio, M., Reyes, R.

“…In geodetic surveys, survey-grade receivers are conventionally used due to their accuracy. However, expensive survey-grade receivers deter users from…”
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Tead and AP1 Coordinate Transcription and Motility by Liu, Xiangfan, Li, Huapeng, Rajurkar, Mihir, Li, Qi, Cotton, Jennifer L., Ou, Jianhong, Zhu, Lihua J., Goel, Hira L., Mercurio, Arthur M., Park, Joo-Seop, Davis, Roger J., Mao, Junhao

“…The Tead family transcription factors are the major intracellular mediators of the Hippo-Yap pathway. Despite the importance of Hippo signaling in…”
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Targeting prominin2 transcription to overcome ferroptosis resistance in cancer by Brown, Caitlin W, Chhoy, Peter, Mukhopadhyay, Dimpi, Karner, Emmet R, Mercurio, Arthur M

“…Understanding how cancer cells resist ferroptosis is a significant problem that impacts ongoing efforts to stimulate ferroptosis as a therapeutic strategy. We…”
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Bullying, Discrimination, Harassment, Sexual Harassment, and the Fear of Retaliation During Surgical Residency Training: A Systematic Review by Gianakos, Arianna L., Freischlag, Julie A., Mercurio, Angela M., Haring, R. Sterling, LaPorte, Dawn M., Mulcahey, Mary K., Cannada, Lisa K., Kennedy, John G.

“…Background The negative effects of bullying, discrimination, harassment, and sexual harassment (BDHS) on well-being and productivity of surgical residents in…”
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Transcriptional regulation of VEGF-A by the unfolded protein response pathway by Ghosh, Rajarshi, Lipson, Kathryn L, Sargent, Karen E, Mercurio, Arthur M, Hunt, Joan S, Ron, David, Urano, Fumihiko

“…Angiogenesis is crucial to many physiological and pathological processes including development and cancer cell survival. Vascular endothelial growth factor-A…”
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A laminin 511 matrix is regulated by TAZ and functions as the ligand for the α6Bβ1 integrin to sustain breast cancer stem cells by Chang, Cheng, Goel, Hira Lal, Gao, Huijie, Pursell, Bryan, Shultz, Leonard D, Greiner, Dale L, Ingerpuu, Sulev, Patarroyo, Manuel, Cao, Shiliang, Lim, Elgene, Mao, Junhao, McKee, Karen Kulju, Yurchenco, Peter D, Mercurio, Arthur M

“…Understanding how the extracellular matrix impacts the function of cancer stem cells (CSCs) is a significant but poorly understood problem. We report that…”
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Regulated Splicing of the α6 Integrin Cytoplasmic Domain Determines the Fate of Breast Cancer Stem Cells by Goel, Hira Lal, Gritsko, Tatiana, Pursell, Bryan, Chang, Cheng, Shultz, Leonard D., Greiner, Dale L., Norum, Jens Henrik, Toftgard, Rune, Shaw, Leslie M., Mercurio, Arthur M.

“…Although the α6β1 integrin has been implicated in the function of breast and other cancer stem cells (CSCs), little is known about its regulation and…”
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The VEGF receptor neuropilin 2 promotes homologous recombination by stimulating YAP/TAZ-mediated Rad51 expression by Elaimy, Ameer L., Amante, John J., Zhu, Lihua Julie, Wang, Mengdie, Walmsley, Charlotte S., FitzGerald, Thomas J., Goel, Hira Lal, Mercurio, Arthur M.

“…Vascular endothelial growth factor (VEGF) signaling in tumor cells mediated by neuropilins (NRPs) contributes to the aggressive nature of several cancers,…”
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Illuminating the Hierarchical Segmentation of Faults Through an Unsupervised Learning Approach Applied to Clouds of Earthquake Hypocenters by Piegari, E., Camanni, G., Mercurio, M., Marzocchi, W.

“…We propose a workflow for the recognition of the hierarchical segmentation of faults through earthquake hypocenter clustering without prior information. Our…”
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No evidence of increased risk for Coronavirus Disease 2019 (COVID‐19) in patients treated with Dupilumab for atopic dermatitis in a high‐epidemic area – Bergamo, Lombardy, Italy by Carugno, A., Raponi, F., Locatelli, A.G., Vezzoli, P., Gambini, D.M., Di Mercurio, M., Robustelli Test, E., Sena, P.

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Inequalities in access to biological treatments for psoriasis: results from the Italian Psocare registry by Naldi, L., Cazzaniga, S., Di Mercurio, M., Grossi, E., Addis, A.

“…Summary Background Limited evidence is available on the impact of socioeconomic factors on drug prescriptions for psoriasis. Objectives To investigate factors…”
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Investigating strontium isotope linkage between biominerals (uroliths), drinking water and environmental matrices by Izzo, F., Di Renzo, V., Langella, A., D'Antonio, M., Tranfa, P., Widory, D., Salzano, L., Germinario, C., Grifa, C., Varricchio, E., Mercurio, M.

“…This study presents the mineralogy and strontium isotope ratio (87Sr/86Sr) of 21 pathological biominerals (bladder and kidney stones) collected from patients…”
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Regulation of IMP3 by EGFR signaling and repression by ERβ: implications for triple-negative breast cancer by Samanta, S, Sharma, V M, Khan, A, Mercurio, A M

“…Insulin-like growth factor II (IGF-II) mRNA-binding protein 3 (IMP3) is emerging as a useful indicator of the progression and outcome of several cancers. IMP3…”
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P-Rex1 Promotes Resistance to VEGF/VEGFR-Targeted Therapy in Prostate Cancer by Goel, Hira Lal, Pursell, Bryan, Shultz, Leonard D., Greiner, Dale L., Brekken, Rolf A., Vander Kooi, Craig W., Mercurio, Arthur M.

“…Autocrine VEGF signaling is critical for sustaining prostate and other cancer stem cells (CSCs), and it is a potential therapeutic target, but we observed that…”
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The calcium channel TRPC6 promotes chemotherapy-induced persistence by regulating integrin α6 mRNA splicing by Mukhopadhyay, Dimpi, Goel, Hira Lal, Xiong, Choua, Goel, Shivam, Kumar, Ayush, Li, Rui, Zhu, Lihua Julie, Clark, Jennifer L., Brehm, Michael A., Mercurio, Arthur M.

“…Understanding the cell biological mechanisms that enable tumor cells to persist after therapy is necessary to improve the treatment of recurrent disease. Here,…”
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