Search Results - "MERCHANT, R. E"

A review of recent clinical trials of the nutritional supplement Chlorella pyrenoidosa in the treatment of fibromyalgia, hypertension, and ulcerative colitis by Merchant, R E, Andre, C A

“…It has been suggested that the consumption of natural "whole foods" rich in macronutrients has many healthful benefits for those who otherwise ingest a normal,…”
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Molecular detection of tumor-associated antigens shared by human cutaneous melanomas and gliomas by Chi, DD, Merchant, RE, Rand, R, Conrad, AJ, Garrison, D, Turner, R, Morton, DL, Hoon, DS

“…Both melanocytes and glial cells are derived embryologically from the neural ectoderm. Their malignant transformed counterparts, melanoma and glioma cells,…”
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A Double-Blind, Placebo-Controlled Study of the Safety, Tolerability and Pharmacokinetics of CP-101,606 in Patients with a Mild or Moderate Traumatic Brain Injury by MERCHANT, RANDALL E., BULLOCK, M. ROSS, CARMACK, CYNTHIA A., SHAH, AJIT K., WILNER, KEITH D., KO, GRANT, WILLIAMS, STEPHEN A.

“…CP‐101,606 is a postsynaptic antagonist of the glutamate‐mediated NR2B subunit of the N‐methyl‐d‐aspartate (NMDA) receptor. When administered intravenously…”
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An Open-Label Study of CP-101,606 in Subjects with a Severe Traumatic Head Injury or Spontaneous Intracerebral Hemorrhage by BULLOCK, M. ROSS, MERCHANT, RANDALL E., CARMACK, CYNTHIA A., DOPPENBERG, EGON, SHAH, AJIT K., WILNER, KEITH D., KO, GRANT, WILLIAMS, STEPHEN A.

“…CP‐101,606 is a postsynaptic antagonist of N‐methyl‐d‐aspartate (NMDA) receptors bearing the NR2B subunit. When administered intravenously (i.v.), it decreases…”
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Interleukin-6 transduction of a rat T9 glioma clone results in attenuated tumorigenicity and induces glioma immunity in Fischer F344 rats by GRAF, M. R, MERCHANT, R. E

“…We transduced a highly tumorigenic T9 clone (T9.F), isolated from the rat T9 glioblastoma cell line, with a retroviral expression vector containing the human…”
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Blood-brain barrier changes following intracerebral injection of human recombinant tumor necrosis factor-α in the rat by WRIGHT, J. L, MERCHANT, R. E

“…Human recombinant tumor necrosis factor-alpha (rTNF-alpha) was administered to normal Fischer 344 rats by stereotaxic intracerebral (IC) injection. Animals…”
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Effects of an intratumoral injection of human recombinant tumor necrosis factor-α on cerebrovascular permeability and leukocytic infiltration in a rat glioma model by WRIGHT, J. L, MERCHANT, R. E

“…The pro-inflammatory and blood-brain barrier (BBB) effects of intratumoral (IT) injection of human recombinant tumor necrosis factor-alpha (rTNF-alpha) were…”
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IL-6 Secretion by a Rat T9 Glioma Clone Induces a Neutrophil-Dependent Antitumor Response with Resultant Cellular, Antiglioma Immunity by Graf, Martin R, Prins, Robert M, Merchant, Randall E

“…Previously, we reported that IL-6 transduction attenuates tumor formation of a rat T9 glioma clone (termed T9.F). This study focuses on the mechanisms of the…”
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In vitro analysis of the proliferative potential of T cells from patients with brain tumor : glioma-associated immunosuppression unrelated to intrinsic cellular defect by MCVICAR, D. W, DAVIS, D. F, MERCHANT, R. E

“…Patients harboring a malignant brain tumor have been described as being highly immunosuppressed, as evidenced by reduced numbers of T cells and the decreased…”
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Adoptive immunotherapy for recurrent glioblastoma multiforme using lymphokine activated killer cells and recombinant interleukin-2 by Merchant, R E, Grant, A J, Merchant, L H, Young, H F

“…Thirteen patients with recurrent glioblastoma were treated with adoptively transferred autologous lymphokine activated killer (LAK) cells and recombinant…”
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Glioma Proliferation Modulated in Vitro by Isothermal Radiofrequency Radiation Exposure by Cleary, Stephen F., Liu, Li-Ming, Merchant, Randall E.

“…Isothermal (37 ± 0.2°C) exposure of glioma cells (LN71) for 2 h to 27 or 2450 MHz continuous-wave radiofrequency (RF) radiation in vitro modulated the rates of…”
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Treatment of recurrent malignant glioma by repeated intracerebral injections of human recombinant interleukin-2 alone or combination with systemic interferon-α. Results of a phase I clinical trial by MERCHANT, R. E, MCVICAR, D. W, MERCHANT, L. H, YOUNG, H. F

“…Nine patients with a recurrent malignant glioma were treated with repeated intracavitary or intracerebroventricular injections of human recombinant…”
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Appearance of cytokine-associated central nervous system myelin damage coincides temporally with serum tumor necrosis factor induction after recombinant interleukin-2 infusion in rats by Ellison, M D, Merchant, R E

“…Endogenous tumor necrosis factor (TNF) activity, assessed by L-929 fibroblast bioassay, was determined in serum samples from rats infused intravenously with…”
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Blood-brain barrier dysfunction in cats following recombinant interleukin-2 infusion by ELLISON, M. D, POVLISHOCK, J. T, MERCHANT, R. E

“…The effects of systemic human recombinant interleukin-2 (rIL-2) infusion upon blood-brain barrier status and cerebral vascular ultrastructure were examined in…”
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Histopathological effects of intracerebral injections of human recombinant tumor necrosis factor-α in the rat by WRIGHT, J. L, MERCHANT, R. E

“…Human recombinant tumor necrosis factor-alpha (rTNF-alpha) was administered to normal Fischer 344 rats by stereotaxic intracerebral (IC) injection. Animals…”
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Interleukin-2 modulates the expression of lymphocyte function-associated antigen-one (LFA-1) and p150,95 during the generation of lymphokine-activated killer (LAK) cells by GRANT, A. J, MERCHANT, R. E, HALL, R. E

“…Lymphocyte function-associated antigen-one (LFA-1), Mac1 and p150,95 represent a family of heterodimeric cell surface molecules with a common beta subunit and…”
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Cardiopulmonary effects of recombinant interleukin-2 infusion in sheep by Glauser, F L, DeBlois, G G, Bechard, D E, Merchant, R E, Grant, A J, Fowler, A A, Fairman, R P

“…The systemic administration of recombinant interleukin-2 (rIL-2) with or without lymphokine-activated killer (LAK) cells, a new treatment for patients with…”
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Systemic treatment with murine recombinant interleukin-1β inhibits the growth and progression of malignant glioma in the rat by RICE, C. D, MERCHANT, R. E

“…We investigated the effects of daily subcutaneous (SC) injections of 100, 200, or 400 micrograms/kg murine recombinant interleukin-1 beta (rIL-1 beta) or its…”
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Acute effects of human recombinant tumor necrosis factor-α on the cerebral vasculature of the rat in both normal brain and in an experimental glioma model by KIDO, G, WRIGHT, J. L, MERCHANT, R. E

“…The effects of intravenous (IV) infusion of human recombinant tumor necrosis factor-alpha (rTNF-alpha, Cetus) on normal brain and malignant glioma in rats were…”
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Low-abundance 32-kilodalton nuclear protein specifically enriched in the central nervous system by Shelton, K R, Cunningham, J G, Klann, E, Merchant, R E, Egle, P M, Bigbee, J W

“…Recently, a low-abundance nuclear protein, p32/6.3, has been identified in brain tissue (Egle and Shelton: Journal of Biological Chemistry 261:2294-2298,…”
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