Search Results - "MENTEN, Björn"

Chromosomal mosaicism in human blastocysts: the ultimate diagnostic dilemma by Popovic, Mina, Dhaenens, Lien, Boel, Annekatrien, Menten, Björn, Heindryckx, Björn

“…Abstract BACKGROUND Trophectoderm (TE) biopsy and next generation sequencing (NGS) are currently the preferred techniques for preimplantation genetic testing…”
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LNCipedia: a database for annotated human lncRNA transcript sequences and structures by Volders, Pieter-Jan, Helsens, Kenny, Wang, Xiaowei, Menten, Björn, Martens, Lennart, Gevaert, Kris, Vandesompele, Jo, Mestdagh, Pieter

“…Here, we present LNCipedia (http://www.lncipedia.org), a novel database for human long non-coding RNA (lncRNA) transcripts and genes. LncRNAs constitute a…”
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Shallow Whole Genome Sequencing on Circulating Cell-Free DNA Allows Reliable Noninvasive Copy-Number Profiling in Neuroblastoma Patients by Van Roy, Nadine, Van Der Linden, Malaïka, Menten, Björn, Dheedene, Annelies, Vandeputte, Charlotte, Van Dorpe, Jo, Laureys, Geneviève, Renard, Marleen, Sante, Tom, Lammens, Tim, De Wilde, Bram, Speleman, Frank, De Preter, Katleen

“…Neuroblastoma (NB) is a heterogeneous disease characterized by distinct clinical features and by the presence of typical copy-number alterations (CNAs). Given…”
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WisecondorX: improved copy number detection for routine shallow whole-genome sequencing by Raman, Lennart, Dheedene, Annelies, De Smet, Matthias, Van Dorpe, Jo, Menten, Björn

“…Abstract Shallow whole-genome sequencing to infer copy number alterations (CNAs) in the human genome is rapidly becoming the method par excellence for routine…”
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A link between host plant adaptation and pesticide resistance in the polyphagous spider mite Tetranychus urticae by Dermauw, Wannes, Wybouw, Nicky, Rombauts, Stephane, Menten, Björn, Vontas, John, Grbic, Miodrag, Clark, Richard M, Feyereisen, René, Van Leeuwen, Thomas

“…Plants produce a wide range of allelochemicals to defend against herbivore attack, and generalist herbivores have evolved mechanisms to avoid, sequester, or…”
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Myxoid pleomorphic liposarcoma—a clinicopathologic, immunohistochemical, molecular genetic and epigenetic study of 12 cases, suggesting a possible relationship with conventional pleomorphic liposarcoma by Creytens, David, Folpe, Andrew L., Koelsche, Christian, Mentzel, Thomas, Ferdinande, Liesbeth, van Gorp, Joost M., Van der Linden, Malaïka, Raman, Lennart, Menten, Björn, Fritchie, Karen, von Deimling, Andreas, Van Dorpe, Jo, Flucke, Uta

“…Myxoid pleomorphic liposarcoma is a recently defined subtype of liposarcoma, which preferentially involves the mediastinum of young patients and shows mixed…”
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BATCH-GE: Batch analysis of Next-Generation Sequencing data for genome editing assessment by Boel, Annekatrien, Steyaert, Woutert, De Rocker, Nina, Menten, Björn, Callewaert, Bert, De Paepe, Anne, Coucke, Paul, Willaert, Andy

“…Targeted mutagenesis by the CRISPR/Cas9 system is currently revolutionizing genetics. The ease of this technique has enabled genome engineering in-vitro and in…”
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Alternative Routes to Induce Naïve Pluripotency in Human Embryonic Stem Cells by Duggal, Galbha, Warrier, Sharat, Ghimire, Sabitri, Broekaert, Dorien, Van der Jeught, Margot, Lierman, Sylvie, Deroo, Tom, Peelman, Luc, Van Soom, Ann, Cornelissen, Ria, Menten, Björn, Mestdagh, Pieter, Vandesompele, Jo, Roost, Matthias, Slieker, Roderick C., Heijmans, Bastiaan T., Deforce, Dieter, De Sutter, Petra, De Sousa Lopes, Susana Chuva, Heindryckx, Björn

“…Human embryonic stem cells (hESCs) closely resemble mouse epiblast stem cells exhibiting primed pluripotency unlike mouse ESCs (mESCs), which acquire a naïve…”
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Low feasibility of in vitro matured oocytes originating from cumulus complexes found during ovarian tissue preparation at the moment of gender confirmation surgery and during testosterone treatment for fertility preservation in transgender men by Lierman, Sylvie, Tolpe, Annelies, De Croo, Ilse, De Gheselle, Stefanie, Defreyne, Justine, Baetens, Machteld, Dheedene, Annelies, Colman, Roos, Menten, Björn, T’Sjoen, Guy, De Sutter, Petra, Tilleman, Kelly

“…To study the feasibility of in vitro maturation of ovarian tissue oocytes for fertility preservation in transgender men on testosterone treatment…”
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Phenotypic and Molecular Heterogeneity in Mandibulofacial Dysostoses: A Case Series From India by Shenoy, Rathika D., Shetty, Vikram, Dheedene, Annelies, Menten, Björn, Pandyanda Nanjappa, Dechamma, Chakraborty, Gunimala, Sips, Patrick, de Paepe, Anne, Callewaert, Bert, Chakraborty, Anirban

“…Objective Facial dysostosis is a group of rare craniofacial congenital disabilities requiring multidisciplinary long-term care. This report presents the…”
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Shallow-depth sequencing of cell-free DNA for Hodgkin and diffuse large B-cell lymphoma (differential) diagnosis: a standardized approach with underappreciated potential by Raman, Lennart, Van der Linden, Malaïka, De Vriendt, Ciel, Van den Broeck, Bliede, Muylle, Kristoff, Deeren, Dries, Dedeurwaerdere, Franceska, Verbeke, Sofie, Dendooven, Amélie, De Grove, Katrien, Baert, Saskia, Claes, Kathleen, Menten, Björn, Offner, Fritz, Van Dorpe, Jo

“…Shallow-depth sequencing of cell-free DNA, a cheap and standardized approach to obtain molecular information on tumors non-invasively, is insufficiently…”
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Identification of long non-coding RNAs involved in neuronal development and intellectual disability by D’haene, Eva, Jacobs, Eva Z., Volders, Pieter-Jan, De Meyer, Tim, Menten, Björn, Vergult, Sarah

“…Recently, exome sequencing led to the identification of causal mutations in 16–31% of patients with intellectual disability (ID), leaving the underlying cause…”
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Shallow whole genome sequencing is well suited for the detection of chromosomal aberrations in human blastocysts by Deleye, Lieselot, M.Sc, Dheedene, Annelies, M.Sc, De Coninck, Dieter, Ph.D, Sante, Tom, M.Sc, Christodoulou, Christodoulos, M.Sc, Heindryckx, Björn, Ph.D, Van den Abbeel, Etienne, Ph.D, De Sutter, Petra, Ph.D, Deforce, Dieter, Ph.D, Menten, Björn, Ph.D, Van Nieuwerburgh, Filip, Ph.D

“…Objective To add evidence that massive parallel sequencing (MPS) is a valuable substitute for array comparative genomic hybridization (arrayCGH) with a…”
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Outcome of publicly funded nationwide first-tier noninvasive prenatal screening by Van Den Bogaert, Kris, Lannoo, Lore, Brison, Nathalie, Gatinois, Vincent, Baetens, Machteld, Blaumeiser, Bettina, Boemer, François, Bourlard, Laura, Bours, Vincent, De Leener, Anne, De Rademaeker, Marjan, Désir, Julie, Dheedene, Annelies, Duquenne, Armelle, Fieremans, Nathalie, Fieuw, Annelies, Gatot, Jean-Stéphane, Grisart, Bernard, Janssens, Katrien, Janssens, Sandra, Lederer, Damien, Marichal, Axel, Menten, Björn, Meunier, Colombine, Palmeira, Leonor, Pichon, Bruno, Sammels, Eva, Smits, Guillaume, Sznajer, Yves, Vantroys, Elise, Devriendt, Koenraad, Vermeesch, Joris Robert

“…Noninvasive prenatal screening (NIPS) using cell-free DNA has transformed prenatal care. Belgium was the first country to implement and fully reimburse NIPS as…”
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Comparative analysis of naive, primed and ground state pluripotency in mouse embryonic stem cells originating from the same genetic background by Ghimire, Sabitri, Van der Jeught, Margot, Neupane, Jitesh, Roost, Matthias S., Anckaert, Jasper, Popovic, Mina, Van Nieuwerburgh, Filip, Mestdagh, Pieter, Vandesompele, Jo, Deforce, Dieter, Menten, Björn, Chuva de Sousa Lopes, Susana, De Sutter, Petra, Heindryckx, Björn

“…Mouse embryonic stem cells (mESCs) exist in a naive, primed and ground state of pluripotency. While comparative analyses of these pluripotency states have been…”
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Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage by Billiet, Lore, De Cock, Laurenz, Sanchez Sanchez, Guillem, Mayer, Rupert L, Goetgeluk, Glenn, De Munter, Stijn, Pille, Melissa, Ingels, Joline, Jansen, Hanne, Weening, Karin, Pascal, Eva, Raes, Killian, Bonte, Sarah, Kerre, Tessa, Vandamme, Niels, Seurinck, Ruth, Roels, Jana, Lavaert, Marieke, Van Nieuwerburgh, Filip, Leclercq, Georges, Taghon, Tom, Impens, Francis, Menten, Björn, Vermijlen, David, Vandekerckhove, Bart

“…In the human thymus, a CD10+ PD-1+ TCRαβ+ differentiation pathway diverges from the conventional single positive T cell lineages at the early double-positive…”
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Human germline nuclear transfer to overcome mitochondrial disease and failed fertilization after ICSI by Tang, Maoxing, Boel, Annekatrien, Castelluccio, Noemi, Cardona Barberán, Arantxa, Christodoulaki, Antonia, Bekaert, Bieke, Popovic, Mina, Vanden Meerschaut, Frauke, De Sutter, Petra, Menten, Björn, Symoens, Sofie, Vanlander, Arnaud V., Stoop, Dominic, Coucke, Paul J., Heindryckx, Björn

“…Purpose Providing additional insights on the efficacy of human nuclear transfer (NT). Here, and earlier, NT has been applied to minimize transmission risk of…”
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PREFACE: In silico pipeline for accurate cell‐free fetal DNA fraction prediction by Raman, Lennart, Baetens, Machteld, De Smet, Matthias, Dheedene, Annelies, Van Dorpe, Jo, Menten, Björn

“…Objective During routine noninvasive prenatal testing (NIPT), cell‐free fetal DNA fraction is ideally derived from shallow‐depth whole‐genome sequencing data,…”
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ViVar: a comprehensive platform for the analysis and visualization of structural genomic variation by Sante, Tom, Vergult, Sarah, Volders, Pieter-Jan, Kloosterman, Wigard P, Trooskens, Geert, De Preter, Katleen, Dheedene, Annelies, Speleman, Frank, De Meyer, Tim, Menten, Björn

“…Structural genomic variations play an important role in human disease and phenotypic diversity. With the rise of high-throughput sequencing tools,…”
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Implicit bias in diagnosing mosaicism amongst preimplantation genetic testing providers: results from a multicenter study of 36 395 blastocysts by Popovic, Mina, Borot, Lorena, Lorenzon, Aline R, Lopes, Ana Luiza Rossi de Castro, Sakkas, Denny, Lledó, Belén, Morales, Ruth, Ortiz, José Antonio, Polyzos, Nikolaos P, Parriego, Mónica, Azpiroz, Felicitas, Galain, Micaela, Pujol, Aïda, Menten, Björn, Dhaenens, Lien, Vanden Meerschaut, Frauke, Stoop, Dominic, Rodriguez, Maria, de la Blanca, Enrique Pérez, Rodríguez, Amelia, Vassena, Rita

“…Does the diagnosis of mosaicism affect ploidy rates across different providers offering preimplantation genetic testing for aneuploidies (PGT-A)? Our analysis…”
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