Search Results - "MENG, XIANZHONG"

Risk factors for surgical site infections following spinal surgery by Meng, Fei, Cao, Junming, Meng, Xianzhong

“…Highlights • We identified risk factors for surgical site infection after spinal surgery. • Smoking, diabetes obesity urinary track infection, hypertension,…”
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Human myocardium releases heat shock protein 27 (HSP27) after global ischemia: the proinflammatory effect of extracellular HSP27 through toll-like receptor (TLR)-2 and TLR4 by Jin, Chunhua, Cleveland, Joseph C, Ao, Lihua, Li, Jilin, Zeng, Qingchun, Fullerton, David A, Meng, Xianzhong

“…The myocardial inflammatory response contributes to cardiac functional injury associated with heart surgery obligating global ischemia/reperfusion (I/R)…”
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Biomechanical Evaluation of Oblique Lumbar Interbody Fusion with Various Fixation Options: A Finite Element Analysis by Song, Chengjie, Chang, Hengrui, Zhang, Di, Zhang, Yingze, Shi, Mingxin, Meng, Xianzhong

“…Objective The aim of the present study was to clarify the biomechanical properties of oblique lumbar interbody fusion (OLIF) using different fixation methods…”
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Pro-inflammatory mediators released by activated monocytes promote aortic valve fibrocalcific activity by Zhang, Peijian, The, Erlinda, Luo, Zichao, Zhai, Yufeng, Yao, Qingzhou, Ao, Lihua, Fullerton, David A, Xu, Dingli, Meng, Xianzhong

“…Calcific aortic valve disease (CAVD) is the most prevalent heart valve disorder in the elderly. Valvular fibrocalcification is a characteristic pathological…”
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Pro-Osteogenic Phenotype of Human Aortic Valve Interstitial Cells Is Associated With Higher Levels of Toll-Like Receptors 2 and 4 and Enhanced Expression of Bone Morphogenetic Protein 2 by Yang, Xiaoping, PhD, Fullerton, David A., MD, Su, Xin, MD, Ao, Lihua, BS, Cleveland, Joseph C., MD, Meng, Xianzhong, MD, PhD

“…Objectives Our aim was to determine whether aortic valve interstitial cells (AVICs) and pulmonary valve interstitial cells (PVICs) differ in expression of…”
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Toll-like Receptor 4 Mediates Oxidized LDL-Induced Macrophage Differentiation to Foam Cells by Howell, Kenneth W., B.A, Meng, Xianzhong, M.D., Ph.D, Fullerton, David A., M.D, Jin, Chunhua, Ph.D, Reece, T. Brett, M.D, Cleveland, Joseph C., M.D

“…Background Macrophage foam cells are central in the development of atherosclerosis, but the mechanism of foam cell formation is unclear. Toll-like receptor 4…”
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Toll-Like Receptor-4 Is a Mediator of Proliferation in Esophageal Adenocarcinoma by Kohtz, Patrick D., Halpern, Alison L., Eldeiry, Mohamed A., Hazel, Kweku, Kalatardi, Shana, Ao, Lihua, Meng, Xianzhong, Reece, T. Brett, Fullerton, David A., Weyant, Michael J.

“…Chronic inflammation from reflux disease has been implicated as part of the development of esophageal adenocarcinoma. Toll-like receptors (TLRs), a component…”
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Klotho suppresses the inflammatory responses and ameliorates cardiac dysfunction in aging endotoxemic mice by Hui, Haipeng, Zhai, Yufeng, Ao, Lihua, Cleveland, Jr, Joseph C, Liu, Hongbin, Fullerton, David A, Meng, Xianzhong

“…Aging augments endotoxemic cardiac dysfunction, but the mechanism remains unclear. Anti-aging protein Klotho has been found to modulate tissue inflammatory…”
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Simvastatin down-regulates osteogenic response in cultured human aortic valve interstitial cells by Jarrett, Michael J., Yao, Qingzhou, Venardos, Neil, Weyant, Michael J., Reece, T. Brett, Meng, Xianzhong, Fullerton, David A.

“…Aortic valve interstitial cells have been implicated in the pathogenesis of aortic stenosis. In response to proinflammatory stimuli, aortic valve interstitial…”
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Biglycan Induces the Expression of Osteogenic Factors in Human Aortic Valve Interstitial Cells via Toll-Like Receptor-2 by Song, Rui, Zeng, Qingchun, Ao, Lihua, Yu, Jessica A, Cleveland, Joseph C, Zhao, Ke-seng, Fullerton, David A, Meng, Xianzhong

“…OBJECTIVE—Although biglycan (BGN) and oxidized low-density lipoprotein (oxLDL) accumulation has been observed in calcific, stenotic aortic valves, their role…”
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Toll-Like Receptor 4–Dependent Microglial Activation Mediates Spinal Cord Ischemia–Reperfusion Injury by Bell, Marshall T., Puskas, Ferenc, Agoston, Viktor A., Cleveland, Joseph C., Freeman, Kirsten A., Gamboni, Fabia, Herson, Paco S., Meng, Xianzhong, Smith, Phillip D., Weyant, Michael J., Fullerton, David A., Reece, T. Brett

“…BACKGROUND—Paraplegia continues to complicate thoracoabdominal aortic interventions. The elusive mechanism of spinal cord ischemia–reperfusion injury has…”
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Oxidized Low Density Lipoprotein Induces Bone Morphogenetic Protein-2 in Coronary Artery Endothelial Cells via Toll-like Receptors 2 and 4 by Su, Xin, Ao, Lihua, Shi, Yi, Johnson, Thomas R., Fullerton, David A., Meng, Xianzhong

“…Vascular calcification is a common complication in atherosclerosis. Bone morphogenetic protein-2 (BMP-2) plays an important role in atherosclerotic vascular…”
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Elevated Expression of TLR2 in Aging Hearts Exacerbates Cardiac Inflammatory Response and Adverse Remodeling Following Ischemia and Reperfusion Injury by Zhai, Yufeng, Ao, Lihua, Yao, Qingzhou, The, Erlinda, Fullerton, David A, Meng, Xianzhong

“…This study tested the hypothesis that Toll-like receptor 2 (TLR2) augments the inflammatory responses and adverse remodeling in aging hearts to exacerbate…”
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Interleukin 37 Suppresses M1 Macrophage Polarization Through Inhibition of the Notch1 and Nuclear Factor Kappa B Pathways by Zhou, Peitao, Li, Qianqin, Su, Shuwen, Dong, Wenhui, Zong, Suyu, Ma, Qiong, Yang, Xi, Zuo, Daming, Zheng, Shaoyi, Meng, Xianzhong, Xu, Dingli, Zeng, Qingchun

“…Macrophage-orchestrated chronic inflammation plays an important role in cardiovascular disease, including accelerating the development of calcific aortic valve…”
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Knockdown of secretory phospholipase A2 IIa reduces lung cancer growth in vitro and in vivo by Yu, Jessica A., MD, Mauchley, David, MD, Li, Howard, MD, Meng, Xianzhong, MD, PhD, Nemenoff, Raphael A., PhD, Fullerton, David A., MD, Weyant, Michael J., MD

“…Objective Group IIa secretory phospholipase A2 (sPLA2 IIa) plays a role in the malignant potential of several epithelial cancers. Nuclear factor kappa B…”
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Bone morphogenic protein 2 induces Runx2 and osteopontin expression in human aortic valve interstitial cells: Role of Smad1 and extracellular signal-regulated kinase 1/2 by Yang, Xiaoping, PhD, Meng, Xianzhong, MD, PhD, Su, Xin, MD, Mauchley, David C., MD, Ao, Lihua, BS, Cleveland, Joseph C., MD, Fullerton, David A., MD

“…Objective Bone morphogenic protein 2 is found in calcified areas of stenotic aortic valves, and prolonged stimulation of aortic valve interstitial cells with…”
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Secretory Phospholipase A2 IIa Mediates Expression of Growth Factor Receptors in Esophageal Adenocarcinoma by Halpern, Alison L., Kohtz, Patrick D., White, Allana M., Houk, Anna K., Rehring, Jacob F., Hanson, Levent, McCarter, Martin. D., Joshi, Molishree, Meng, Xianzhong, Fullerton, David A., Weyant, Michael J.

“…Background Receptor tyrosine kinases of the epidermal growth factor receptor (EGFR) family such as human epidermal receptor-2 (HER2) are involved in the…”
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Biomechanical Analysis of Double‐Level Oblique Lumbar Fusion with Different Types of Fixation: A Finite Element‐Based Study by Fan, Kaibin, Zhang, Di, Xue, Rui, Chen, Wei, Hou, Zhiyong, Zhang, Yingze, Meng, Xianzhong

“…Objective One well‐liked less invasive procedure is oblique lumbar interbody fusion (OLIF). The biomechanical characteristics of double‐level oblique lumbar…”
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TLR4 Stimulation Promotes Human AVIC Fibrogenic Activity through Upregulation of Neurotrophin 3 Production by Yao, Qingzhou, The, Erlinda, Ao, Lihua, Zhai, Yufeng, Osterholt, Maren K, Fullerton, David A, Meng, Xianzhong

“…Calcific aortic valve disease (CAVD) is a chronic inflammatory disease that manifests as progressive valvular fibrosis and calcification. An inflammatory…”
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Cross-Talk Between the Toll-Like Receptor 4 and Notch1 Pathways Augments the Inflammatory Response in the Interstitial Cells of Stenotic Human Aortic Valves by QINGCHUN ZENG, CHUNHUA JIN, LIHUA AO, CLEVELAND, Joseph C, RUI SONG, DINGLI XU, FULLERTON, David A, XIANZHONG MENG

“…Calcific aortic stenosis is a chronic inflammatory disease, and aortic valve interstitial cells (AVIC) play an important role in valvular inflammation. Whereas…”
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