Search Results - "MENDLEWICZ, Julien"

Sleep disturbances: Core symptoms of major depressive disorder rather than associated or comorbid disorders by Mendlewicz, Julien

“…Depression is increasingly prevalent in Western countries. It has severe consequences and is associated with increased rates of disability, morbidity, and…”
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European Group for the Study of Resistant Depression (GSRD) — Where have we gone so far: Review of clinical and genetic findings by Schosser, Alexandra, Serretti, Alessandro, Souery, Daniel, Mendlewicz, Julien, Zohar, Joseph, Montgomery, Stuart, Kasper, Siegfried

“…Abstract The primary objective of this review is to give an overview of the main findings of the European multicenter project “Patterns of Treatment Resistance…”
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The sociodemographic and clinical profile of patients with major depressive disorder receiving SSRIs as first-line antidepressant treatment in European countries by Fugger, Gernot, Bartova, Lucie, Fabbri, Chiara, Fanelli, Giuseppe, Dold, Markus, Swoboda, Marleen Margret Mignon, Kautzky, Alexander, Zohar, Joseph, Souery, Daniel, Mendlewicz, Julien, Montgomery, Stuart, Rujescu, Dan, Serretti, Alessandro, Kasper, Siegfried

“…Introduction Due to favorable antidepressant (AD) efficacy and tolerability, selective-serotonin reuptake inhibitors (SSRIs) are consistently recommended as…”
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Age as a moderating factor of treatment resistance in depression by Kautzky, Alexander, Bartova, Lucie, Fugger, Gernot, Dold, Markus, Souery, Daniel, Montgomery, Stuart, Zohar, Joseph, Mendlewicz, Julien, Fabbri, Chiara, Serretti, Alessandro, Rujescu, Dan, Kasper, Siegfried

“…Treatment-resistant depression (TRD) is an important clinical challenge and may present differently between age groups. A total of 893 depressed patients…”
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Major Depression and Comorbid Diabetes - Findings from the European Group for the Study of Resistant Depression by Fugger, Gernot, Dold, Markus, Bartova, Lucie, Kautzky, Alexander, Souery, Daniel, Mendlewicz, Julien, Serretti, Alessandro, Zohar, Joseph, Montgomery, Stuart, Frey, Richard, Kasper, Siegfried

“…The major aim of this multicenter study of the European Group for the Study of Resistant Depression (GSRD) was to elucidate associations between major…”
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A polygenic predictor of treatment-resistant depression using whole exome sequencing and genome-wide genotyping by Fabbri, Chiara, Kasper, Siegfried, Kautzky, Alexander, Zohar, Joseph, Souery, Daniel, Montgomery, Stuart, Albani, Diego, Forloni, Gianluigi, Ferentinos, Panagiotis, Rujescu, Dan, Mendlewicz, Julien, Uher, Rudolf, Lewis, Cathryn M., Serretti, Alessandro

“…Treatment-resistant depression (TRD) occurs in ~30% of patients with major depressive disorder (MDD) but the genetics of TRD was previously poorly…”
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Working memory-related functional brain patterns in never medicated children with ADHD by Massat, Isabelle, Slama, Hichem, Kavec, Martin, Linotte, Sylvie, Mary, Alison, Baleriaux, Daniele, Metens, Thierry, Mendlewicz, Julien, Peigneux, Philippe

“…Attention Deficit/Hyperactivity Disorder (ADHD) is a pervasive neurodevelopmental disorder characterized by 3 clusters of age-inappropriate cardinal symptoms:…”
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Temperament and character profiles in bipolar I, bipolar II and major depressive disorder: Impact over illness course, comorbidity pattern and psychopathological features of depression by Zaninotto, Leonardo, Souery, Daniel, Calati, Raffaella, Di Nicola, Marco, Montgomery, Stuart, Kasper, Siegfried, Zohar, Joseph, Mendlewicz, Julien, Robert Cloninger, C, Serretti, Alessandro, Janiri, Luigi

“…Abstract Background Studies comparing temperament and character traits between patients with mood disorders and healthy individuals have yielded variable…”
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Genetics of schizophrenia: A consensus paper of the WFSBP Task Force on Genetics by Giegling, Ina, Hosak, Ladislav, Mössner, Rainald, Serretti, Alessandro, Bellivier, Frank, Claes, Stephan, Collier, David A., Corrales, Alejo, DeLisi, Lynn E., Gallo, Carla, Gill, Michael, Kennedy, James L., Leboyer, Marion, Maier, Wolfgang, Marquez, Miguel, Massat, Isabelle, Mors, Ole, Muglia, Pierandrea, Nöthen, Markus M., Ospina-Duque, Jorge, Owen, Michael J., Propping, Peter, Shi, YongYong, St Clair, David, Thibaut, Florence, Cichon, Sven, Mendlewicz, Julien, O'Donovan, Michael C., Rujescu, Dan

“…Objectives: Schizophrenia is a severe psychiatric disease affecting about 1% of the general population. The relative contribution of genetic factors has been…”
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Time-dependent effects of escitalopram on brain derived neurotrophic factor (BDNF) and neuroplasticity related targets in the central nervous system of rats by Alboni, Silvia, Benatti, Cristina, Capone, Giacomo, Corsini, Daniela, Caggia, Federica, Tascedda, Fabio, Mendlewicz, Julien, Brunello, Nicoletta

“…Chronic treatment with antidepressants affects several proteins linked to neuroplasticity, particularly brain derived neurotrophic factor (BDNF): this leads…”
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Shortened onset of action of antidepressants in major depression using acetylsalicylic acid augmentation: a pilot open-label study by Mendlewicz, Julien, Kriwin, Philippe, Oswald, Pierre, Souery, Daniel, Alboni, Silvia, Brunello, Nicoletta

“…Based on our preclinical data showing a potential accelerating effect of acetylsalicylic acid (ASA) in combination with fluoxetine in an animal model of…”
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Possible Modulatory Role of ARC Gene Variants in Mood Disorders by Crisafulli, Concetta, Calabrò, Marco, Mandelli, Laura, Wang, Sheng-Min, Lee, Soo-Jung, Han, Changsu, Patkar, Ashwin, Masand, Prakash, Pae, Chi-Un, Souery, Daniel, Mendlewicz, Julien, Serretti, Alessandro

“…The genetic background of mood disorders is gradually emerging through the use of large multicenter samples but a detailed phenotyping is complementary in…”
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CYP2C19 genotype predicts steady state escitalopram concentration in GENDEP by Huezo-Diaz, Patricia, Perroud, Nader, Spencer, Edgar P, Smith, Rebecca, Sim, Sarah, Virding, Susanne, Uher, Rudolf, Gunasinghe, Cerisse, Gray, Jo, Campbell, Desmond, Hauser, Joanna, Maier, Wolfgang, Marusic, Andrej, Rietschel, Marcella, Perez, Jorge, Giovannini, Caterina, Mors, Ole, Mendlewicz, Julien, McGuffin, Peter, Farmer, Anne E, Ingelman-Sundberg, Magnus, Craig, Ian W, Aitchison, Katherine J

“…In vitro work shows CYP2C19 and CYP2D6 contribute to the metabolism of escitalopram to its primary metabolite, N-desmethylescitalopram. We report the effect of…”
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Transcriptional profiles underlying vulnerability and resilience in rats exposed to an acute unavoidable stress by Benatti, Cristina, Valensisi, Cristina, Blom, Joan M.C., Alboni, Silvia, Montanari, Claudia, Ferrari, Francesco, Tagliafico, Enrico, Mendlewicz, Julien, Brunello, Nicoletta, Tascedda, Fabio

“…A complex interplay between gene and environment influences the vulnerability or the resilience to stressful events. In the acute escape deficit (AED)…”
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Acetylsalicylic acid accelerates the antidepressant effect of fluoxetine in the chronic escape deficit model of depression by Brunello, Nicoletta, Alboni, Silvia, Capone, Giacomo, Benatti, Cristina, Blom, Joan M.C, Tascedda, Fabio, Kriwin, Philippe, Mendlewicz, Julien

“…Evidence has accumulated suggesting that major depression is associated with dysfunction of inflammatory mediators. Moreover, antidepressants show an…”
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Identification of a CACNA2D4 deletion in late onset bipolar disorder patients and implications for the involvement of voltage-dependent calcium channels in psychiatric disorders by Van Den Bossche, Maarten J., Strazisar, Mojca, De Bruyne, Stephan, Bervoets, Chris, Lenaerts, An-Sofie, De Zutter, Sonia, Nordin, Annelie, Norrback, Karl-Fredrik, Goossens, Dirk, De Rijk, Peter, Green, Elaine K., Grozeva, Detelina, Mendlewicz, Julien, Craddock, Nick, Sabbe, Bernard G., Adolfsson, Rolf, Souery, Daniel, Del-Favero, Jurgen

“…The GWAS‐based association of CACNA1C with bipolar disorder (BPD) is one of the strongest genetic findings to date. CACNA1C belongs to the family of CACN genes…”
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Disruption of the Circadian Timing Systems: Molecular Mechanisms in Mood Disorders by Mendlewicz, Julien

“…Depression is one of the leading causes of morbidity worldwide and represents a huge burden to society. As with many other psychiatric disorders, a genetic…”
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Dimensions of Delusions in Major Depression: Socio-demographic and Clinical Correlates in an Unipolar-Bipolar Sample by Zaninotto, Leonardo, Souery, Daniel, Calati, Raffaella, Camardese, Giovanni, Janiri, Luigi, Montgomery, Stuart, Kasper, Siegfried, Zohar, Joseph, De Ronchi, Diana, Mendlewicz, Julien, Serretti, Alessandro

“…The present study aims at exploring associations between a continuous measure of distorted thought contents and a set of demographic and clinical features in a…”
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Posttraumatic stress disorder: diagnosis and epidemiology, comorbidity and social consequences, biology and treatment by Brunello, N, Davidson, J R, Deahl, M, Kessler, R C, Mendlewicz, J, Racagni, G, Shalev, A Y, Zohar, J

“…Epidemiological studies clearly indicate that posttraumatic stress disorder (PTSD) is becoming a major health concern worldwide even if still poorly recognized…”
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Noradrenaline in mood and anxiety disorders: basic and clinical studies by Brunello, Nicoletta, Blier, Pier, Judd, Lewis L, Mendlewicz, Julien, Nelson, Craig J, Souery, Daniel, Zohar, Joseph, Racagni, Giorgio

“…The neurotransmitter noradrenaline is known to be involved in a range of physiological and psychological processes, and dysfunctions of this neurotransmitter…”
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